Zobrazeno 1 - 10
of 58
pro vyhledávání: '"Aviv Regev"'
Autor:
Charles R. Vanderburg, Evan Z. Macosko, Aviv Regev, Velina Kozareva, Wade G. Regehr, Chong Guo, Stephanie Rudolph, Tomas Osorno, Naeem Nadaf, Caroline Martin
Publikováno v:
Nature
The cerebellar cortex is a well-studied brain structure with diverse roles in motor learning, coordination, cognition and autonomic regulation. However, a complete inventory of cerebellar cell types is currently lacking. Here, using recent advances i
Autor:
Orit Rozenblatt-Rosen, Markus A. Schramm, Aviv Regev, Marcin Tabaka, Ana C. Anderson, Karen O. Dixon, Ruihan Tang, Vijay K. Kuchroo, Danielle Dionne, Sheng Xiao
Publikováno v:
Nature
T cell immunoglobulin and mucin-containing molecule 3 (TIM-3), first identified as a molecule expressed on interferon-γ producing T cells1, is emerging as an important immune-checkpoint molecule, with therapeutic blockade of TIM-3 being investigated
Autor:
Himisha Beltran, David Liu, Kelly P. Burke, Sébastien Vigneau, Amalia R. Sweet, Parin Shah, Natalie I. Vokes, Zhenwei Zhang, Keyan Salari, Abhay Kanodia, Laura DelloStritto, Christopher Rodman, Orit Rozenblatt-Rosen, Rebecca Silver, Xin Yuan, Sabrina Y. Camp, Sheng-Yu Ku, Meng Xiao He, Mary-Ellen Taplin, Lawrence Fong, Nathan C Walk, Kevin Bi, John A. Steinharter, Steven P. Balk, Eliezer M. Van Allen, Asaf Rotem, Aviv Regev, Alok K. Tewari, Maria Mica Garcia, Jihye Park, Mei-Ju Su, Benjamin Izar, Jett Crowdis, Ziad Bakouny, Alice Bosma-Moody, Joshua W. Russo, Michael S. Cuoco
Publikováno v:
Nature Medicine
Metastatic castration-resistant prostate cancer is typically lethal, exhibiting intrinsic or acquired resistance to second-generation androgen-targeting therapies and minimal response to immune checkpoint inhibitors1. Cellular programs driving resist
Autor:
Aviv Regev, Eugene Drokhlyansky, Jozef Ukropec, Christian Wolfrum, Lucia Balazova, Gottfried Rudofsky, Wenfei Sun, Antonio Giordano, Lianggong Ding, Miroslav Balaz, Anna Sofie Husted, Patrik Stefanicka, Georgia Colleluori, Michal Slyper, Saverio Cinti, Zuzana Kovanicova, Thue W. Schwartz, Hua Dong
Publikováno v:
Cell Metab
Adipose tissue is usually classified on the basis of its function as white, brown or beige (brite)1. It is an important regulator of systemic metabolism, as shown by the fact that dysfunctional adipose tissue in obesity leads to a variety of secondar
Autor:
Vamsi K. Mootha, Amel Karaa, Caleb A. Lareau, Leif S. Ludwig, Vijay G. Sankaran, Aviv Regev, Melissa A. Walker
Publikováno v:
N Engl J Med
Many mitochondrial diseases are caused by mutations in mitochondrial DNA (mtDNA). Patients' cells contain a mixture of mutant and nonmutant mtDNA (a phenomenon called heteroplasmy). The proportion of mutant mtDNA varies across patients and among tiss
Autor:
Moshe Biton, Mesruh Turkekul, Charles L. Sawyers, Anuradha Gopalan, Matan Hofree, Alborz Bejnood, Vincent P. Laudone, Wassim Abida, Katia Manova, Ignas Masilionis, Eliot Linton, Ojasvi Chaudhary, Linas Mazutis, Tianhao Xu, Wouter R. Karthaus, Brett S. Carver, Dana Pe'er, Danielle Choi, Aviv Regev
Publikováno v:
Science. 368:497-505
Equal opportunity tissue regeneration Tissue regeneration is thought to be driven primarily by rare stem cells with distinctive properties. Single-cell RNA sequencing allows rigorous testing of this hypothesis. Karthaus et al. examined the regenerati
Autor:
Jonathan Y. Kim, Michael E. Birnbaum, Patricia Rogers, Olivia Smith, Tyler Jacks, Celeste Dang, Arjun Bhutkar, Aviv Regev, Jason M. Schenkel, Michelle Hillman, Amy Li, David Canner, Livnat Jerby-Arnon, Le Cong, Orit Rozenblatt-Rosen, Rebecca H. Herbst, C. Garrett Rappazzo, Michael S. Cuoco
Publikováno v:
Cell Reports, Vol 29, Iss 10, Pp 2998-3008.e8 (2019)
Summary: Regulatory T cells (Tregs) can impair anti-tumor immune responses and are associated with poor prognosis in multiple cancer types. Tregs in human tumors span diverse transcriptional states distinct from those of peripheral Tregs, but their c
Autor:
Sangeeta S. Chavan, Coco Chu, Aviv Regev, Conor Liston, David Artis, Lei Zhou, Frank C. Schroeder, Meghan E. Addorisio, Saya Moriyama, Anfei Li, Tae Hyung Won, Ruirong Yang, Mitchell H. Murdock, Heidi C. Meyer, Fei Teng, Gregory G. Putzel, Adam M. Kressel, Kevin J. Tracey, Nicholas J. Bessman, Deqiang Jing, Hattie Chung, Christopher N. Parkhurst, Tea Tsaava, Francis S. Lee
Publikováno v:
Nature
Multicellular organisms have co-evolved with complex consortia of viruses, bacteria, fungi and parasites, collectively referred to as the microbiota1. In mammals, changes in the composition of the microbiota can influence many physiologic processes (
Autor:
William J. Greenleaf, Sarah A. Teichmann, Margaret Vella, Ajay Pillai, Aviv Regev, Ananda L. Roy, Kristin E. Burnum-Johnson, Cole Trapnell, Yiing Lin, Marda Jorgensen, Gloria S. Pryhuber, Leslie Gaffney, Ken S. Lau, Kimberly Robasky, Jeffrey M. Spraggins, Chuck McCallum, Stavros Michailidis, Randy Heiland, Orit Rozenblatt-Rosen, Allyson Ricarte, Xin bSun, Kevin J. Otto, Amir Bahmani, Zorina S. Galis, James S. Hagood, Monica Nagendran, Gökcen Eraslan, Robin M. Scibek, Jocelyn Y. Kishi, Jay Mulye, Maria Keays, Griffin M. Weber, Caltech-UW Tmc, Charles Ansong, Nicholas A. Nystrom, Vishal G. Venkataraaman, Vladimir Yu. Kiselev, Ucsd Tmc, Ellen M. Quardokus, Tushar bDesai, Bruce Herr, Engagement Component, James E. Anderson, Shin Lin, Lisel Record, Peter V. Kharchenko, Robert F. dMurphy, Stanford-WashU Tmc, Yu Wang, Jian Ma, Sergio Maffioletti, Sarah Black, Matthew Ruffalo, Salvatore Sechi, John C. Marioni, Ziv Bar-Joseph, Richard M. Caprioli, Stanford Ttd, Garry P. Nolan, Marishka Brown, Elizabeth L. Wilder, Maigan A. Brusko, Peter Chou, Tommaso Biancalani, Christian Martijn Schuerch, Julia Laskin, Richard Conroy, Jonathan C. Silverstein, Paula M. Mabee, Dena Procaccini, Pehr B. Harbury, Michael Snyder, Pothur Srinivas, Jennifer Rood, Dana Jackson, Sanjay Jain, Katy Börner, Visualization HuBMAP Integration, William E. Shirey, Sinem K. Saka, James P. Sluka, Agnes B. Fogo, Isabel Goldaracena, Sushma A. Akoju, Raymond C. Harris, Rahul Satija, Sylvia K. Plevritis, Tim Stuart, Shila Ghazanfar, Peng Yin, Harvard Ttd, Aaron M. Horning, Ed Esplin, Amanda Posgai, Michael J. Clare-Salzler, Raf Van de Plas, Aaron Pawlyk, Guo-Cheng Yuan, Benedict aten, DongHye Ye, Hayan Lee, Eyal Fisher, Jay Shendure, Long Cai, Danielle cGutierrez, Carl Kingsford, Ruben Dries, Sara Ahadi, Paul D. Piehowski, Bernd bBodenmiller, Purdue Ttd, Stephanie A. Nevins, Philip D. Blood, Andrew Butler, W. Christopher Lenhardt, Ying Zhu, Alexander J. Ropelewski, Harry S. Nick, Nathan Heath Patterson, Elizabeth K. Neumann, Anna Hupalowska, Samuel H. Friedman, Clive hWasserfall, Qian Zhu, Mark P. deCaestecker, Leonard E. Cross, Mark A. Atkinson, Paul Macklin, Todd M. Brusko, Eeshit Dhaval Vaishnav, Nils Gehlenborg, Kun Zhang
Publikováno v:
Nature
Transformative technologies are enabling the construction of three-dimensional maps of tissues with unprecedented spatial and molecular resolution. Over the next seven years, the NIH Common Fund Human Biomolecular Atlas Program (HuBMAP) intends to de
Autor:
Owen White, Kimberly A. Smith, Brian D. Aevermann, William J. Romanow, Joseph R. Ecker, Michael Tieu, Michael Hawrylycz, Sheng-Yong Niu, Brian R. Herb, Jacinta Lucero, Sten Linnarsson, Tanya L. Daigle, Christine S. Liu, Ed S. Lein, Boudewijn P. F. Lelieveldt, Zizhen Yao, Yang Eric Li, Stephan Fischer, Trygve E. Bakken, Jeremy A. Miller, C. Dirk Keene, Scott F. Owen, Wei Tian, Joshua Orvis, Nongluk Plongthongkum, Rosa Castanon, Megan Crow, Thomas Höllt, Bing Ren, Darren Bertagnolli, Weixiu Dong, Herman Tung, Baldur van Lew, Delissa McMillen, Bosiljka Tasic, Angeline Rivkin, Eran A. Mukamel, Nora Reed, Alexander Dobin, Chongyuan Luo, Patrick R. Hof, Nick Dee, Rongxin Fang, Kirsten Crichton, M. Margarita Behrens, Anna Bartlett, Renee Zhang, Olivier Poirion, Josef Sulc, Philip R. Nicovich, Rebecca D. Hodge, Evan Z. Macosko, Staci A. Sorensen, Dinh Diep, Thanh Pham, Songlin Ding, Richard H. Scheuermann, Jayaram Kancherla, Jeroen Eggermont, Seth A. Ament, Ronna Hertzano, Jeff Goldy, Christine Rimorin, Julia K. Osteen, Kimberly Siletti, Steven A. McCarroll, Hanqing Liu, C. Palmer, Saroja Somasundaram, Jonathan T. Ting, Jerold Chun, Xiaomeng Hou, Guoping Feng, Kun Zhang, Fenna M. Krienen, Blue B. Lake, Amy Torkelson, Hongkui Zeng, Sebastian Preissl, Christof Koch, Nikolas L. Jorstad, Andrew L. Ko, Héctor Corrada Bravo, Aviv Regev, Nikolai C. Dembrow, Kanan Lathia, Antonio Pinto-Duarte, Xinxin Wang, Lucas T. Graybuck, Melissa Goldman, Marmar Moussa, William J. Spain, Peter V. Kharchenko, Qiwen Hu, Adriana E. Sedeno-Cortes, Gregory D. Horwitz, Rachel A. Dalley, Anup Mahurkar, Brian E. Kalmbach, Andrew Aldridge, Jesse Gillis, Anna Marie Yanny, Joseph R. Nery, Tamara Casper, Fangming Xie, Matthew Kroll
Publikováno v:
Nature, 598(7879), 111-119. NATURE PORTFOLIO
Nature
Nature: international weekly journal of science, 598(7879)
Nature
Nature: international weekly journal of science, 598(7879)
The primary motor cortex (M1) is essential for voluntary fine-motor control and is functionally conserved across mammals1. Here, using high-throughput transcriptomic and epigenomic profiling of more than 450,000 single nuclei in humans, marmoset monk
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec172c4ec74873eefac841febd1a5574
https://www.nature.com/articles/s41586-021-03465-8.pdf
https://www.nature.com/articles/s41586-021-03465-8.pdf