Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Amy R Bentley"'
Autor:
Karlijn A. C. Meeks, Amy R. Bentley, Ayo P. Doumatey, Adebowale A. Adeyemo, Charles N. Rotimi
Publikováno v:
Scientific reports. 12(1)
Adiponectin has been associated with cardiometabolic traits in observational studies across populations, yet it is unclear if these associations are causal. We performed Mendelian randomization (MR) analysis to assess the relationship between adipone
Autor:
Reem Kais Jan, Daniel L. Kastner, Francesco Boin, Chris T. Derk, Kathleen D. Kolstad, Vivien Hsu, Heather Gladue, Virginia D. Steen, Avram Goldberg, Paula S. Ramos, Victoria K. Shanmugam, Dinesh Khanna, Lorinda Chung, Ayo P. Doumatey, Richard M. Silver, Elana J. Bernstein, Amy R. Bentley, Pravitt Gourh, Nadia D. Morgan, Ami A. Shah, Maureen D. Mayes, Lesley Ann Saketkoo, Fredrick M. Wigley, Steven E. Boyden, Brynn Kron, Elena Schiopu, Benjamin D. Korman, Lindsey A. Criswell, Peter J. Steinbach, S. Louis Bridges, Suzanne Kafaja, Thomas A. Medsger, Daniel Shriner, James C. Mullikin, Settara C. Chandrasekharappa, Jessica K. Gordon, Robyn T. Domsic, Elaine F. Remmers, John Varga, Adebowale Adeyemo, Sarah A. Safran, Theresa Alexander, Marcin Trojanowski, Charles N. Rotimi
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, vol 117, iss 1
Proceedings of the National Academy of Sciences of the United States of America, vol 117, iss 1
Significance HLA alleles have previously been implicated with scleroderma risk, but, in this study, using a European American ancestral cohort and a newly recruited large cohort of African Americans, we comprehensively define the HLA alleles and amin
Autor:
Sina A. Gharib, Kenneth Rice, Donna K. Arnett, Tõnu Esko, Annemarie I. Luik, Niki Dimou, Dabeeru C. Rao, Pamela J. Schreiner, Melissa A. Richard, Reedik Mägi, Nicholette D. Palmer, Stefan Weiss, Han Chen, Solomon K. Musani, W. James Gauderman, Christian Gieger, Kari E. North, Salman M. Tajuddin, Diana van Heemst, Rainer Rauramaa, Stephen B. Kritchevsky, Henry Völzke, Minjung Kho, Michele K. Evans, Ruth J. F. Loos, Correa Adolfo, Pedro Marques-Vidal, Diane M. Becker, Claude Bouchard, José Haba-Rubio, Georg Homuth, Kurt Lohman, Nora Franceschini, Caizheng Yu, Peter Vollenweider, Ervin F. Fox, Thomas Meitinger, Karen Schwander, Heming Wang, Morris A. Swertz, Aldi T. Kraja, José Eduardo Krieger, Xiuqing Guo, Tangchun Wu, Raymond Noordam, Yongmei Liu, Michael R. Brown, Patrick C.N. Rensen, Annette Peters, Jingmin Liu, Tuomo Rankinen, Robert B. Wallance, Timo A. Lakka, Stephen S. Rich, Yun Ju Sung, Meian He, Till Roenneberg, Wanqing Wen, Dennis O. Mook-Kanamori, M. A. Province, Evangelos Evangelou, L. Adrienne Cupples, Maxime M Bos, Paul S. de Vries, Hans J. Grabe, Lisa R. Yanek, Jiwon Lee, Mario Sims, Bruce M. Psaty, Treva Rice, Tanika N. Kelly, Brenda W.J.H. Penninx, Brigitte Kühnel, Maria E. Graff, Alexandre C. Pereira, Daniel J. Gottlieb, Charles N. Rotimi, Lynne E. Wagenknecht, Ashley van der Spek, Lisa W. Martin, Jeffrey R. O'Connell, Changwei Li, James E. Hixson, Chuan Gao, Alisa K. Manning, Sharon L.R. Kardia, Stella Aslibekyan, Andres Metspalu, Sami Heikkinen, Maris Alver, Xiao-Ou Shu, Amy R. Bentley, Susan Redline, Konstantin Strauch, Tamara B. Harris, Yuri Milaneschi, L.F. Bielak, Marjan Ilkov, Myriam Fornage, Ilja M. Nolte, André G. Uitterlinden, Dina Vojinovic, Hugues Aschard, Paul Elliott, Kent D. Taylor, Najaf Amin, James M. Shikany, Yong-Bing Xiang, Jerome I. Rotter, Vilmundur Gudnason, Cornelia M. van Duijn, Ko Willems van Dijk, Andrea R. V. R. Horimoto, Jonathan Marten, Olli T. Raitakari, Vincent Laville, Pirjo Komulainen, Zhe Wang, Traci M. Bartz, Mary F. Feitosa, Mike A. Nalls, Eric Boerwinkle, Alanna C. Morrison, Melanie Waldenberger, Alexander P. Reiner, Christie M. Ballantyne, Wei Zheng, Raphael Heinzer, M. Arfan Ikram, Colleen M. Sitlani, Lisa de las Fuentes, Patricia B. Munroe, Patricia A. Peyser, Brian E. Cade, Tamar Sofer, Xiaofeng Zhu, Nienke R. Biermasz, Harold Snieder, Elise Lim, Tuomas O. Kilpeläinen, Ching-Ti Liu, Terho Lehtimäki, Thomas W. Winkler, Leo-Pekka Lyytikäinen, Gudny Eiriksdottir, Stephen Sidney, Alan B. Zonderman, Charles Kooperberg
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Nature Communications
Nature Communications, 2019, 10 (1), pp.5121. ⟨10.1038/s41467-019-12958-0⟩
Nature Communications, 10. NATURE PUBLISHING GROUP
Nature Communications, 10:5121. Nature Publishing Group
Nature Communications, 10(1):5121. Nature Publishing Group
Nature Communications, 10(1):5121. Nature Publishing Group UK
Noordam, R, Bos, M M, Wang, H, Winkler, T W, Bentley, A R, Kilpeläinen, T O, de Vries, P S, Sung, Y J, Schwander, K, Cade, B E, Manning, A, Aschard, H, Brown, M R, Chen, H, Franceschini, N, Musani, S K, Richard, M, Vojinovic, D, Aslibekyan, S, Bartz, T M, de las Fuentes, L, Feitosa, M, Horimoto, A R, Ilkov, M, Kho, M, Kraja, A, Li, C, Lim, E, Liu, Y, Mook-Kanamori, D O, Rankinen, T, Tajuddin, S M, van der Spek, A, Wang, Z, Marten, J, Laville, V, Alver, M, Evangelou, E, Graff, M E, He, M, Kühnel, B, Lyytikäinen, L P, Marques-Vidal, P, Nolte, I M, Palmer, N D, Rauramaa, R, Shu, X O, Snieder, H, Weiss, S & Penninx, B W J H 2019, ' Multi-ancestry sleep-by-SNP interaction analysis in 126,926 individuals reveals lipid loci stratified by sleep duration ', Nature Communications, vol. 10, no. 1, 5121 . https://doi.org/10.1038/s41467-019-12958-0
Nature Communications, Nature Publishing Group, 2019, 10 (1), pp.5121. ⟨10.1038/s41467-019-12958-0⟩
Noordam, R, Bos, M M, Wang, H, Winkler, T W, Bentley, A R, Kilpeläinen, T O, de Vries, P S, Sung, Y J, Schwander, K, Cade, B E, Manning, A, Aschard, H, Brown, M R, Chen, H, Franceschini, N, Musani, S K, Richard, M, Vojinovic, D, Aslibekyan, S, Bartz, T M, de Las Fuentes, L, Feitosa, M, Horimoto, A R, Ilkov, M, Kho, M, Kraja, A, Li, C, Lim, E, Liu, Y, Mook-Kanamori, D O, Rankinen, T, Tajuddin, S M, van der Spek, A, Wang, Z, Marten, J, Laville, V, Alver, M, Evangelou, E, Graff, M E, He, M, Kühnel, B, Lyytikäinen, L-P, Marques-Vidal, P, Nolte, I M, Palmer, N D, Rauramaa, R, Shu, X-O, Snieder, H, Weiss, S, Wen, W, Yanek, L R, Adolfo, C, Ballantyne, C, Bielak, L, Biermasz, N R, Boerwinkle, E, Dimou, N, Eiriksdottir, G, Gao, C, Gharib, S A, Gottlieb, D J, Haba-Rubio, J, Harris, T B, Heikkinen, S, Heinzer, R, Hixson, J E, Homuth, G, Ikram, M A, Komulainen, P, Krieger, J E, Lee, J, Liu, J, Lohman, K K, Luik, A I, Mägi, R, Martin, L W, Meitinger, T, Metspalu, A, Milaneschi, Y, Nalls, M A, O'Connell, J, Peters, A, Peyser, P, Raitakari, O T, Reiner, A P, Rensen, P C N, Rice, T K, Rich, S S, Roenneberg, T, Rotter, J I, Schreiner, P J, Shikany, J, Sidney, S S, Sims, M, Sitlani, C M, Sofer, T, Strauch, K, Swertz, M A, Taylor, K D, Uitterlinden, A G, van Duijn, C M, Völzke, H, Waldenberger, M, Wallance, R B, van Dijk, K W, Yu, C, Zonderman, A B, Becker, D M, Elliott, P, Esko, T, Gieger, C, Grabe, H J, Lakka, T A, Lehtimäki, T, North, K E, Penninx, B W J H, Vollenweider, P, Wagenknecht, L E, Wu, T, Xiang, Y-B, Zheng, W, Arnett, D K, Bouchard, C, Evans, M K, Gudnason, V, Kardia, S, Kelly, T N, Kritchevsky, S B, Loos, R J F, Pereira, A C, Province, M, Psaty, B M, Rotimi, C, Zhu, X, Amin, N, Cupples, L A, Fornage, M, Fox, E F, Guo, X, Gauderman, W J, Rice, K, Kooperberg, C, Munroe, P B, Liu, C-T, Morrison, A C, Rao, D C, van Heemst, D & Redline, S 2019, ' Multi-ancestry sleep-by-SNP interaction analysis in 126,926 individuals reveals lipid loci stratified by sleep duration ', Nature Communications, vol. 10, no. 1, 5121 . https://doi.org/10.1038/s41467-019-12958-0
Nature communications, vol. 10, no. 1, pp. 5121
Nature Communications
Nature Communications, 2019, 10 (1), pp.5121. ⟨10.1038/s41467-019-12958-0⟩
Nature Communications, 10. NATURE PUBLISHING GROUP
Nature Communications, 10:5121. Nature Publishing Group
Nature Communications, 10(1):5121. Nature Publishing Group
Nature Communications, 10(1):5121. Nature Publishing Group UK
Noordam, R, Bos, M M, Wang, H, Winkler, T W, Bentley, A R, Kilpeläinen, T O, de Vries, P S, Sung, Y J, Schwander, K, Cade, B E, Manning, A, Aschard, H, Brown, M R, Chen, H, Franceschini, N, Musani, S K, Richard, M, Vojinovic, D, Aslibekyan, S, Bartz, T M, de las Fuentes, L, Feitosa, M, Horimoto, A R, Ilkov, M, Kho, M, Kraja, A, Li, C, Lim, E, Liu, Y, Mook-Kanamori, D O, Rankinen, T, Tajuddin, S M, van der Spek, A, Wang, Z, Marten, J, Laville, V, Alver, M, Evangelou, E, Graff, M E, He, M, Kühnel, B, Lyytikäinen, L P, Marques-Vidal, P, Nolte, I M, Palmer, N D, Rauramaa, R, Shu, X O, Snieder, H, Weiss, S & Penninx, B W J H 2019, ' Multi-ancestry sleep-by-SNP interaction analysis in 126,926 individuals reveals lipid loci stratified by sleep duration ', Nature Communications, vol. 10, no. 1, 5121 . https://doi.org/10.1038/s41467-019-12958-0
Nature Communications, Nature Publishing Group, 2019, 10 (1), pp.5121. ⟨10.1038/s41467-019-12958-0⟩
Noordam, R, Bos, M M, Wang, H, Winkler, T W, Bentley, A R, Kilpeläinen, T O, de Vries, P S, Sung, Y J, Schwander, K, Cade, B E, Manning, A, Aschard, H, Brown, M R, Chen, H, Franceschini, N, Musani, S K, Richard, M, Vojinovic, D, Aslibekyan, S, Bartz, T M, de Las Fuentes, L, Feitosa, M, Horimoto, A R, Ilkov, M, Kho, M, Kraja, A, Li, C, Lim, E, Liu, Y, Mook-Kanamori, D O, Rankinen, T, Tajuddin, S M, van der Spek, A, Wang, Z, Marten, J, Laville, V, Alver, M, Evangelou, E, Graff, M E, He, M, Kühnel, B, Lyytikäinen, L-P, Marques-Vidal, P, Nolte, I M, Palmer, N D, Rauramaa, R, Shu, X-O, Snieder, H, Weiss, S, Wen, W, Yanek, L R, Adolfo, C, Ballantyne, C, Bielak, L, Biermasz, N R, Boerwinkle, E, Dimou, N, Eiriksdottir, G, Gao, C, Gharib, S A, Gottlieb, D J, Haba-Rubio, J, Harris, T B, Heikkinen, S, Heinzer, R, Hixson, J E, Homuth, G, Ikram, M A, Komulainen, P, Krieger, J E, Lee, J, Liu, J, Lohman, K K, Luik, A I, Mägi, R, Martin, L W, Meitinger, T, Metspalu, A, Milaneschi, Y, Nalls, M A, O'Connell, J, Peters, A, Peyser, P, Raitakari, O T, Reiner, A P, Rensen, P C N, Rice, T K, Rich, S S, Roenneberg, T, Rotter, J I, Schreiner, P J, Shikany, J, Sidney, S S, Sims, M, Sitlani, C M, Sofer, T, Strauch, K, Swertz, M A, Taylor, K D, Uitterlinden, A G, van Duijn, C M, Völzke, H, Waldenberger, M, Wallance, R B, van Dijk, K W, Yu, C, Zonderman, A B, Becker, D M, Elliott, P, Esko, T, Gieger, C, Grabe, H J, Lakka, T A, Lehtimäki, T, North, K E, Penninx, B W J H, Vollenweider, P, Wagenknecht, L E, Wu, T, Xiang, Y-B, Zheng, W, Arnett, D K, Bouchard, C, Evans, M K, Gudnason, V, Kardia, S, Kelly, T N, Kritchevsky, S B, Loos, R J F, Pereira, A C, Province, M, Psaty, B M, Rotimi, C, Zhu, X, Amin, N, Cupples, L A, Fornage, M, Fox, E F, Guo, X, Gauderman, W J, Rice, K, Kooperberg, C, Munroe, P B, Liu, C-T, Morrison, A C, Rao, D C, van Heemst, D & Redline, S 2019, ' Multi-ancestry sleep-by-SNP interaction analysis in 126,926 individuals reveals lipid loci stratified by sleep duration ', Nature Communications, vol. 10, no. 1, 5121 . https://doi.org/10.1038/s41467-019-12958-0
Nature communications, vol. 10, no. 1, pp. 5121
Publisher's version (útgefin grein).
Both short and long sleep are associated with an adverse lipid profile, likely through different biological pathways. To elucidate the biology of sleep-associated adverse lipid profile, we conduct multi-ance
Both short and long sleep are associated with an adverse lipid profile, likely through different biological pathways. To elucidate the biology of sleep-associated adverse lipid profile, we conduct multi-ance
Autor:
Michèle Ramsay, Mahtaab Hayat, Robyn Kerr, Frederick J. Raal, Amy R. Bentley, Charles N. Rotimi
Publikováno v:
PLoS ONE
PLoS ONE, Vol 15, Iss 2, p e0229098 (2020)
PLoS ONE, Vol 16, Iss 3, p e0249478 (2021)
PLoS ONE, Vol 15, Iss 2, p e0229098 (2020)
PLoS ONE, Vol 16, Iss 3, p e0249478 (2021)
Non-communicable diseases, including cardiovascular diseases (CVDs), are increasing in African populations. High serum low density lipoprotein cholesterol (LDL-cholesterol) levels are a known risk factor for CVDs in European populations, but the link
Autor:
Alexandre C. Pereira, Jie Yao, Makoto Hirata, Ozren Polasek, Dragana Vuckovic, Mariaelisa Graff, Jing Hua Zhao, Michael R. Brown, Xuan Deng, Barbara V. Howard, Vilmundur Gudnason, Tuomo Rankinen, Yuan Shi, Timo A. Lakka, Ulrich Broeckel, Anuradhani Kasturiratne, Eric Boerwinkle, Charles Kooperberg, Hugues Aschard, Stephen S. Rich, Pamela J. Schreiner, Dan E. Arking, Hans J. Grabe, Ilaria Gandin, Mario Sims, Carl D. Langefeld, Yii-Der Ida Chen, Meian He, W. James Gauderman, Bruce M. Psaty, Kent D. Taylor, Tõnu Esko, Olli T. Raitakari, Saima Afaq, Maik Pietzner, Federica Laguzzi, Dennis O. Mook-Kanamori, Gregory P. Wilson, Xiuqing Guo, Jaspal S. Kooner, David R. Jacobs, Yajuan Wang, Raha Pazoki, Wei Zhao, Andres Metspalu, Mary F. Feitosa, Jost B. Jonas, Tin Aung, Tamara B. Harris, Karin Leander, Nancy L. Pedersen, Charles B. Eaton, Sharon L.R. Kardia, Bernardo L. Horta, Candace M. Kammerer, Terrence Forrester, Alexander P. Reiner, Paul W. Franks, Tanika N. Kelly, Igor Rudan, Ruben N. Eppinga, Melissa A. Richard, Colin A. McKenzie, Christine Williams, Christian Gieger, Joseph H. Lee, Brigitte Kühnel, Christopher P. Nelson, Wen Bin Wei, Antonietta Robino, Anne U. Jackson, E. Shyong Tai, Alisa K. Manning, Lisa R. Yanek, Paul Elliott, Lynne E. Wagenknecht, Ananda R. Wickremasinghe, José Eduardo Krieger, Peter S. Sever, Nora Franceschini, André G. Uitterlinden, Paul M. Ridker, Yun J. Sung, Karen L. Mohlke, Thomas H. Mosley, Nilesh J. Samani, Patricia B. Munroe, Jennifer A. Smith, John M. C. Connell, H. Janaka de Silva, Nicholas Y. Q. Tan, Jian'an Luan, Jennifer E. Huffman, Anna F. Dominiczak, Carsten Oliver Schmidt, Christie M. Ballantyne, Peter J. van der Most, Anuj Goel, Jerome I. Rotter, Amy R. Bentley, Lihua Wang, Rajkumar Dorajoo, Lenore J. Launer, Yechiel Friedlander, Mickaël Canouil, Traci M. Bartz, Thomas Meitinger, Robert A. Scott, Mike A. Nalls, Xueling Sim, Sarah E. Harris, Michael A. Province, Chew-Kiat Heng, Zhe Wang, Norihiro Kato, Evangelos Evangelou, Philippe Froguel, Virginia Fisher, Leslie J. Raffel, Renée de Mutsert, Michele K. Evans, Brenda W.J.H. Penninx, Yih Chung Tham, Tin Louie, Nana Matoba, Lawrence F. Bielak, Andrea R. V. R. Horimoto, Jingmin Liu, Lynda M. Rose, Nona Sotoodehnia, Daniel I. Chasman, Jasmin Divers, John M. Starr, Patricia A. Peyser, Ervin R. Fox, Barry I. Freedman, Megan L. Grove, Jeffrey R. O'Connell, Rob M. van Dam, Michiaki Kubo, Jessica D. Faul, Fang-Chi Hsu, Yize Li, Ilja M. Nolte, Caroline Hayward, Paolo Gasparini, Chiea Chuen Khor, Changwei Li, Xu Chen, James E. Hixson, Patrik K. E. Magnusson, John C. Chambers, Yoichiro Kamatani, Sami Heikkinen, M. Abdullah Said, Martin Farrall, Alena Stančáková, Konstantin Strauch, Albert V. Smith, Yik Ying Teo, Bamidele O. Tayo, Tamar Sofer, Caizheng Yu, Maris Alver, Oscar H. Franco, Yongmei Liu, Ioanna Ntalla, Myriam Fornage, W. Craig Johnson, Dina Vojinovic, William R. Scott, David R. Weir, Yanick Hagemeijer, Raymond Noordam, Mathilde Boissel, Cornelia M. van Duijn, Karen Schwander, Jingzhong Ding, James Scott, Diana van Heemst, Ching-Yu Cheng, Woon-Puay Koh, Jianjun Liu, Kenneth J. Mukamal, Blair H. Smith, Claude Bouchard, Claudia Langenberg, Jingjing Liang, Wei Zheng, Najaf Amin, Ulf de Faire, Bing Yu, Archie Campbell, Kari E. North, Salman M. Tajuddin, Fernando Pires Hartwig, Steve B. Kritchevsky, Tibor V. Varga, Pirjo Komulainen, Hugh Watkins, Johanna Kuusisto, Kurt Lohman, Rozenn N. Lemaitre, Ani Manichaikul, Dabeeru C. Rao, Kenneth Rice, Weihua Zhang, Franco Giulianini, Reedik Mägi, Solomon K. Musani, Wanqing Wen, Nicholas J. Wareham, Charles N. Rotimi, Marzyeh Amini, Rainer Rauramaa, Nicholette D. Palmer, Annette Peters, Neil R Poulter, Benjamin Lehne, Matthias Nauck, Harold Snieder, Donald W. Bowden, M. Arfan Ikram, Lisa de las Fuentes, C. Charles Gu, Xiaofeng Zhu, Markku Laakso, Tuomas O. Kilpeläinen, Ching-Ti Liu, Michael Boehnke, Jin-Fang Chai, Lili Milani, L. Adrienne Cupples, Yuri Milaneschi, Kiang Liu, Stephen Sidney, Alan B. Zonderman, Thomas W. Winkler, Ian J. Deary, Fumihiko Takeuchi, Mary K. Wojczynski, Pim van der Harst, Leo-Pekka Lyytikäinen, Jennifer G. Robinson, Chuan Gao, Xiao-Ou Shu, Diane M. Becker, Mohsen Ghanbari, Alanna C. Morrison, Jian-Min Yuan, Tomohiro Katsuya, Ivana Kolcic, Melanie Waldenberger, Terho Lehtimäki, Heikki A. Koistinen, Erin B. Ware, Ya Xing Wang, Marie Loh, Treva Rice, Qing Duan, Aldi T. Kraja, Sabanayagam Charumathi, Tien Yin Wong, Paul S. de Vries, Yujie Wang, Muhammad Riaz
Publikováno v:
American Journal of Epidemiology, 188(6), 1033-1054. Oxford University Press
American Journal of Epidemiology, 188(6), 1033-1054. OXFORD UNIV PRESS INC
American Journal of Epidemiology
American Journal of Epidemiology, 2019, 188 (6), pp.1033-1054. ⟨10.1093/aje/kwz005⟩
American Journal of Epidemiology, Oxford University Press (OUP), 2019, 188 (6), pp.1033-1054. ⟨10.1093/aje/kwz005⟩
2019, ' Multi-Ancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions ', American Journal of Epidemiology . https://doi.org/10.1093/aje/kwz005
American journal of epidemiology, vol 188, iss 6
De Vries, P S, Lifelines Cohort Study, Brown, M R, Bentley, A R, Sung, Y J, Winkler, T W, Ntalla, I, Schwander, K, Kraja, A T, Guo, X, Franceschini, N, Cheng, C Y, Sim, X, Vojinovic, D, Huffman, J E, Musani, S K, Li, C, Feitosa, M F, Richard, M A, Noordam, R, Aschard, H, Bartz, T M, Bielak, L F, Deng, X, Dorajoo, R, Lohman, K K, Manning, A K, Rankinen, T, Smith, A V, Tajuddin, S M, Evangelou, E, Graff, M, Alver, M, Boissel, M, Chai, J F, Chen, X, Divers, J, Gandin, I, Gao, C, Goel, A, Hagemeijer, Y, Harris, S E, Hartwig, F P, He, M, Horimoto, A R V R, Hsu, F C, Jackson, A U, Kasturiratne, A, Komulainen, P, Kühnel, B, Laguzzi, F, Penninx, BWJH & Lifelines Cohort 2019, ' Multiancestry Genome-Wide Association study of lipid levels incorporating gene-alcohol interactions ', American Journal of Epidemiology, vol. 188, no. 6, pp. 1033-1054 . https://doi.org/10.1093/aje/kwz005
Am J Epidemiol
American journal of epidemiology, 188(6), 1033-1054. Oxford University Press
American Journal of Epidemiology, 188(6), 1033-1054. OXFORD UNIV PRESS INC
American Journal of Epidemiology
American Journal of Epidemiology, 2019, 188 (6), pp.1033-1054. ⟨10.1093/aje/kwz005⟩
American Journal of Epidemiology, Oxford University Press (OUP), 2019, 188 (6), pp.1033-1054. ⟨10.1093/aje/kwz005⟩
2019, ' Multi-Ancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions ', American Journal of Epidemiology . https://doi.org/10.1093/aje/kwz005
American journal of epidemiology, vol 188, iss 6
De Vries, P S, Lifelines Cohort Study, Brown, M R, Bentley, A R, Sung, Y J, Winkler, T W, Ntalla, I, Schwander, K, Kraja, A T, Guo, X, Franceschini, N, Cheng, C Y, Sim, X, Vojinovic, D, Huffman, J E, Musani, S K, Li, C, Feitosa, M F, Richard, M A, Noordam, R, Aschard, H, Bartz, T M, Bielak, L F, Deng, X, Dorajoo, R, Lohman, K K, Manning, A K, Rankinen, T, Smith, A V, Tajuddin, S M, Evangelou, E, Graff, M, Alver, M, Boissel, M, Chai, J F, Chen, X, Divers, J, Gandin, I, Gao, C, Goel, A, Hagemeijer, Y, Harris, S E, Hartwig, F P, He, M, Horimoto, A R V R, Hsu, F C, Jackson, A U, Kasturiratne, A, Komulainen, P, Kühnel, B, Laguzzi, F, Penninx, BWJH & Lifelines Cohort 2019, ' Multiancestry Genome-Wide Association study of lipid levels incorporating gene-alcohol interactions ', American Journal of Epidemiology, vol. 188, no. 6, pp. 1033-1054 . https://doi.org/10.1093/aje/kwz005
Am J Epidemiol
American journal of epidemiology, 188(6), 1033-1054. Oxford University Press
© The Author(s) 2019. A person's lipid profile is influenced by genetic variants and alcohol consumption, but the contribution of interactions between these exposures has not been studied. We therefore incorporated gene-Alcohol interactions into a m
Autor:
Guanjie Chen, Eduardo Tarazona-Santos, Eleanor M. Simonsick, Mateus H. Gouveia, Charles N. Rotimi, Karlijn Meeks, Daniel Shriner, Maria Fernanda Lima-Costa, Mike A. Nalls, Kenneth Ekoru, Adebowale Adeyemo, Hampton L. Leonard, Amy R. Bentley
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Scientific Reports
Scientific Reports
Genome-wide association studies (GWAS) have identified thousands of genetic loci associated with cross-sectional blood pressure (BP) traits; however, GWAS based on longitudinal BP have been underexplored. We performed ethnic-specific and trans-ethnic
Autor:
Lin Lei, Jie Zhou, Karlijn Meeks, Ayo P. Doumatey, Charles N. Rotimi, Mateus H. Gouveia, Amy R. Bentley, Adebowale Adeyemo, Guanjie Chen
Publikováno v:
Circulation. Genomic and precision medicine. 13(5)
Background - Resistin, a protein linked with inflammation and cardiometabolic diseases, is one of few proteins for which GWAS consistently report variants within and near the coding gene ( RETN ). Here, we took advantage of the reduced linkage disequ
Autor:
Kenneth Ekoru, Charles N. Rotimi, Guanjie Chen, Ayo P. Doumatey, Amy R. Bentley, Adebowale Adeyemo, Daniel Shriner, Jie Zhou
Publikováno v:
eLife, Vol 9 (2020)
eLife
eLife
Given a lifetime risk of ~90% by the ninth decade of life, it is unknown if there are true controls for hypertension in epidemiological and genetic studies. Here, we use the Bayesian framework to compare logistic and time-to-event approaches to model
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f4204c9dd6a55b2b21bc2930cd2cc27
Autor:
Jie Zhou, Guanjie Chen, Amy R. Bentley, Daniel Shriner, Ayo P. Doumatey, Adebowale Adeyemo, Lin Lei, Charles N. Rotimi
Publikováno v:
Hum Mol Genet
ObjectiveSerum uric acid is the end-product of purine metabolism and at high levels is a risk factor for several human diseases including gout and cardiovascular disease. Heritability estimates range from 0.32 to 0.63. Genome-wide association studies
Autor:
Bamidele O. Tayo, RJ Waken, Mario Sims, Diane M. Becker, Tõnu Esko, Yingchang Lu, Pamela J. Schreiner, Antonietta Robino, Anne U. Jackson, H. Janaka de Silva, Peter J. van der Most, Archie Campbell, Ozren Polasek, Salman M. Tajuddin, Jing Hua Zhao, Barbara V. Howard, Saima Afaq, Vilmundur Gudnason, Lynda M. Rose, Francis S. Collins, Massimiliano Cocca, Ruth J. F. Loos, Yii-Der Ida Chen, W. James Gauderman, Jaspal S. Kooner, Lawrence F. Bielak, Ulrich Broeckel, Anuradhani Kasturiratne, Melissa A. Richard, Tomohiro Katsuya, Nicola D. Kerrison, Tin Aung, Lisa de las Fuentes, Lynne E. Wagenknecht, Oscar H. Franco, Yongmei Liu, Eric Boerwinkle, Nana Matoba, Saskia P. Hagenaars, Rob M. van Dam, Tibor V. Varga, Nilesh J. Samani, Tangchun Wu, Thomas H. Mosley, Caroline Hayward, Joseph H. Lee, Frida Renström, Tamara B. Harris, Alena Stančáková, Adesola Ogunniyi, Wen Bin Wei, Lenore J. Launer, Marcus Dörr, Xiuqing Guo, Jennifer A. Smith, Terho Lehtimäki, Dan E. Arking, Fang-Chi Hsu, Karin Leander, Martin Farrall, Konstantin Strauch, Albert V. Smith, Richard S. Cooper, Chiea Chuen Khor, Changwei Li, James E. Hixson, Sami Heikkinen, David R. Weir, Pirjo Komulainen, Renée de Mutsert, Raymond Noordam, Ubaydah Nasri, Paul M. Ridker, C. Charles Gu, Tamuno Alfred, Jerome I. Rotter, Nora Franceschini, Nita G. Forouhi, Lihua Wang, Alanna C. Morrison, Jian-Min Yuan, Ching-Yu Cheng, Peter S. Braund, Paul Elliott, Gregory P. Wilson, Jianjun Liu, Xiaofeng Zhu, Markku Laakso, Christian Gieger, Yukihide Momozawa, Rainer Rettig, Carsten Oliver Schmidt, Amy R. Bentley, Wei Zhao, Ioanna Ntalla, Kenneth Rice, Yoichiro Kamatani, Andres Metspalu, Helen R. Warren, Yechiel Friedlander, Susan Redline, Kurt Lohman, Cornelia M. van Duijn, Aravinda Chakravarti, Traci M. Bartz, Sarah E. Harris, Yih Chung Tham, He Gao, Mike A. Nalls, Mathilde Boissel, Donna K. Arnett, Harold Snieder, James S. Pankow, Babatunde L. Salako, Laura J. Bierut, Tin Louie, Albertine J. Oldehinkel, Xueling Sim, Thomas Meitinger, Maris Alver, Claudia Langenberg, Stephen B. Kritchevsky, Norihiro Kato, Evangelos Evangelou, Philippe Froguel, Alexandre C. Pereira, Michael R. Brown, Karen Schwander, Charles Kooperberg, Blair H. Smith, Annette Peters, Fernando Pires Hartwig, Yanhua Zhou, Jie Yao, Alisa K. Manning, Keng-Hung Lin, Dennis O. Mook-Kanamori, Ervin R. Fox, Tuomo Rankinen, Timo A. Lakka, Charles N. Rotimi, Nicholette D. Palmer, Jiang He, Nicholas J. Wareham, Jingmin Liu, Yun Ju Sung, Cathy C. Laurie, Donald W. Bowden, Yong-Bing Xiang, Lisa R. Yanek, B. Kuhnel, Nancy L. Pedersen, Yajuan Wang, Ananda R. Wickremasinghe, Jonathan Marten, Yi-Jen Hung, Dabeeru C. Rao, Bernardo L. Horta, Joel D. Kaufman, Barry I. Freedman, Chuan Gao, Olli T. Raitakari, Reedik Mägi, Solomon K. Musani, Albert Hofman, Wanqing Wen, Heming Wang, Xiao-Ou Shu, Y Liu, Mark J. Caulfield, Meian He, Daniel I. Chasman, Carl D. Langefeld, Charumathi Sabanayagam, Bruce M. Psaty, Jasmin Divers, R. Graham Barr, Chew-Kiat Heng, Stella Aslibekyan, John M. Starr, Stefan Weiss, Anuj Goel, Tuomas O. Kilpeläinen, Terrence Forrester, Mary F. Feitosa, Jost B. Jonas, Kae-Woei Liang, Colleen M. Sitlani, Daniel Levy, Marie Loh, Qing Duan, Aldi T. Kraja, Tien Yin Wong, Myriam Fornage, Andrea R. V. R. Horimoto, Michele K. Evans, David J. Porteous, Dina Vojinovic, Hua Tang, Michael A. Province, Ching-Ti Liu, Rainer Rauramaa, William R. Scott, Cora E. Lewis, Charles B. Eaton, Sharon L.R. Kardia, Michael Boehnke, James Scott, Colin A McKenzie, Jin-Fang Chai, Woon-Puay Koh, Yucheng Jia, Claude Bouchard, Peter S. Sever, Koichi Matsuda, Najaf Amin, Ulf de Faire, Walter Palmas, André G. Uitterlinden, Thomas T. Perls, Erin B. Ware, Wayne Huey-Herng Sheu, Michiaki Kubo, Ya Xing Wang, Hugh Watkins, Steven C. Hunt, Weihua Zhang, Johanna Kuusisto, Lili Milani, Rajkumar Dorajoo, Georg Ehret, L. Adrienne Cupples, Franco Giulianini, Zoltán Kutalik, Jose E Krieger, Kevin Sandow, Bruna Gigante, Alexander P. Reiner, Preeti Gupta, Heikki A. Koistinen, Treva Rice, Patricia B. Munroe, Wen-Jane Lee, Jennifer A. Brody, Paolo Gasparini, Paul W. Franks, Yik Ying Teo, Leo-Pekka Lyytikäinen, Thomas W. Winkler, Patricia A. Peyser, Ian J. Deary, Jessica D. Faul, Sing Hui Lim, Fumihiko Takeuchi, Xu Chen, Brian E. Cade, Patrik K. E. Magnusson, John C. Chambers, Tamar Sofer, E. Shyong Tai, Candace M Kammerer, Mary K. Wojczynski, Pim van der Harst, Marzyeh Amini, Jennifer G. Robinson, Erwin P. Bottinger, Alan B. Zonderman, Benjamin Lehne, M. Waldenberger, Jeffrey R. O'Connell, Hugues Aschard, Ilaria Gandin, Kent D. Taylor, Igor Rudan, Christopher P. Nelson, John M. C. Connell, Jian'an Luan, Mickaël Canouil, Robert A. Scott, Yize Li, Marguerite R. Irvin
Publikováno v:
Hum Mol Genet
Human Molecular Genetics
Human Molecular Genetics, Oxford University Press (OUP), 2019, 28 (15), pp.2615-2633. ⟨10.1093/hmg/ddz070⟩
Human Molecular Genetics, 2019, 28 (15), pp.2615-2633. ⟨10.1093/hmg/ddz070⟩
Human Molecular Genetics, 28(15), 2615-2633. Oxford University Press
Human Molecular Genetics, 28(15), 2615-2633. OXFORD UNIV PRESS
2019, ' A multi-ancestry genome-wide study incorporating gene-smoking interactions identifies multiple new loci for pulse pressure and mean arterial pressure ', Human Molecular Genetics . https://doi.org/10.1093/hmg/ddz070
Human Molecular Genetics, Vol. 28, No 15 (2019) pp. 2615-2633
Human Molecular Genetics
Human Molecular Genetics, Oxford University Press (OUP), 2019, 28 (15), pp.2615-2633. ⟨10.1093/hmg/ddz070⟩
Human Molecular Genetics, 2019, 28 (15), pp.2615-2633. ⟨10.1093/hmg/ddz070⟩
Human Molecular Genetics, 28(15), 2615-2633. Oxford University Press
Human Molecular Genetics, 28(15), 2615-2633. OXFORD UNIV PRESS
2019, ' A multi-ancestry genome-wide study incorporating gene-smoking interactions identifies multiple new loci for pulse pressure and mean arterial pressure ', Human Molecular Genetics . https://doi.org/10.1093/hmg/ddz070
Human Molecular Genetics, Vol. 28, No 15 (2019) pp. 2615-2633
Elevated blood pressure (BP), a leading cause of global morbidity and mortality, is influenced by both genetic and lifestyle factors. Cigarette smoking is one such lifestyle factor. Across five ancestries, we performed a genome-wide gene–smoking in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5654ae9b91f97c8df58b8fa976a56c73
https://europepmc.org/articles/PMC6644157/
https://europepmc.org/articles/PMC6644157/