Zobrazeno 1 - 10
of 41
pro vyhledávání: '"ZHAO LI"'
Autor:
Jin Yan, Yuan Zhang, Lin Wang, Zhao Li, Shuang Tang, Yingwen Wang, Nina Gu, Xiaochuan Sun, Lin Li
Publikováno v:
Journal of Neuroinflammation. 19
Background Neuroinflammation is one of the most important processes in secondary injury after traumatic brain injury (TBI). Triggering receptor expressed on myeloid cells 2 (TREM2) has been proven to exert neuroprotective effects in neurodegenerative
Autor:
Aie Xu, Yangyang Ma, Mengyan Zhu, Jiaqi Wang, Wenzhong Yu, Yongping Xu, Xiaoyan Zhang, Ping Wang, Yong Li, Zhao Li
Publikováno v:
Journal of Investigative Dermatology. 141:374-384
Ubiquitin-conjugating enzyme E2S (UBE2S) is involved in protein degradation and signal transduction, but its function in the development of melanoma is unclear. We focused on the role of UBE2S in melanoma development both in vitro and in vivo. UBE2S
Autor:
Ping, Zhan, Xue, Lu, Zhao, Li, Wen-Jing, Wang, Kun, Peng, Nan-Nan, Liang, Yan, Wang, Jian, Li, Lin, Fu, Hui, Zhao, De-Xiang, Xu, Zhu-Xia, Tan
Publikováno v:
International Immunopharmacology. 113:109359
Numerous studies demonstrated that bleomycin (BLM) caused acute lung injury (ALI). This study explored the role of mitochondrial reactive oxygen species (ROS) on BLM-induced ALI and pulmonary epithelial ferroptosis. Male C57BL/6J mice were intratrach
Intestinal Flora Composition Determines Microglia Activation and Improves Epileptic Episode Progress
Autor:
Ding, Xiaomi, Zhou, Jing, Zhao, Li, Chen, Mingyue, Wang, Shenglin, Zhang, Ming, Zhang, Xiaodong, Jiang, Guohui
Publikováno v:
Frontiers in cellular and infection microbiology. 12
In response to environmental stimuli, immune memory mediates the plasticity of myeloid cells. Immune training and immune tolerance are two aspects of plasticity. Microglia that are immunologically trained or immunologically tolerant are endowed with
Publikováno v:
Brain, Behavior, and Immunity. 81:509-522
ATP-sensitive potassium (K-ATP) channels, coupling cell metabolism to cell membrane potential, are involved in brain diseases, including Parkinson's disease (PD). Kir6.1, a pore-forming subunit of K-ATP channel, is prominently expressed in astrocytes
Publikováno v:
Frontiers in Immunology
Frontiers in Immunology, Vol 12 (2021)
Frontiers in Immunology, Vol 12 (2021)
RationaleDisruption of intracellular calcium (Ca2+) homeostasis is implicated in inflammatory responses. Here we investigated endoplasmic reticulum (ER) Ca2+ efflux through the Inositol 1,4,5-trisphosphate receptor (IP3R) as a potential mechanism of
Autor:
Xuemei Deng, Yong-Xing He, Weifan Jiang, Tao Shi, Zhen Wang, Hanzhong Feng, Dan Liu, Honghua Zhang, Yingmei Lu, Yiyue Feng, Jian Zhang, Junfang Li, Zhao Li
Publikováno v:
European journal of medicinal chemistry. 227
Although gastric cancer has become a major public health problem, oral agents applied in clinics for gastric cancer therapy are scarce. Therefore, to explore new oral chemical entities with high efficiency and low toxicity, 41 o-aminobenzamide deriva
Publikováno v:
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 1179
The root and rhizome of Sophora tonkinensis Gagnep. (ST) are widely used for the treatment of tonsillitis, sore throats, and heat-evil-induced diseases in traditional Chinese medicine. However, the clinical application of ST is relatively limited due
Autor:
Gui-Ying Wang, Xiuli Wang, Wen-Jie Cheng, Cai-Zhen Yan, Yue-Xian Guo, Peng Liu, Zhao Li, Shuang Zhao
Publikováno v:
Mediators of Inflammation, Vol 2021 (2021)
Mediators of Inflammation
Mediators of Inflammation
Background and Objectives. Tourniquet-induced ischemia/reperfusion (I/R) injury is a common clinical problem for patients receiving surgery. The objective of this study is to determine if oxycodone (Oxy) reduces skeletal muscle I/R damage induced by
Autor:
Siyi Wu, Zhao Li, Mengling Ye, Chunxia Liu, Hao Liu, Xiaojing He, Yi Qin, Fangte Liang, Linghui Pan, Fei Lin
Publikováno v:
BioMed Research International, Vol 2021 (2021)
BioMed Research International
BioMed Research International
Lung ischemia reperfusion injury (LIRI) is a complex pathophysiological process with high morbidity and mortality. An important pathophysiological characteristic of LIRI is endothelial barrier dysfunction, although the mechanism involved in this proc