Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Laurent Becquemont"'
Autor:
A. Rigal, Severine Martin, Philippe Chanson, Céline Verstuyft, Florence Gressier, E. Loeb, K. El Asmar, Emmanuelle Corruble, Romain Colle, Bruno Fève, Laurent Becquemont, Séverine Trabado
Publikováno v:
Psychological Medicine. 52:80-89
BackgroundNitric oxide synthase (NOS) activity, an enzyme potentially involved in the major depressive episodes (MDE), could be indirectly measured by the L-Citrulline/L-Arginine ratio (L-Cit/L-Arg). The aim of this study was: (1) to compare the NOS
Autor:
Céline Verstuyft, Elise Lebigot, Bruno Fève, Pierre Mesdom, Eric Deflesselle, Laurent Becquemont, Romain Colle, Séverine Trabado, Emmanuelle Corruble
Publikováno v:
Current Neuropharmacology
Background:Human dermal fibroblasts (HDF) can be used as a cellular model relatively easily and without genetic engineering. Therefore, HDF represent an interesting tool to study several human diseases including psychiatric disorders. Despite major d
Autor:
Vianney Poinsignon, Romain Colle, Khalil El Asmar, Indira Mendez-David, Denis J David, Abd El Kader Ait Tayeb, Kenneth Chappell, Florence Gressier, Hugo Herrero, Bruno Fève, Laurent Becquemont, Emmanuelle Corruble, Céline Verstuyft
Publikováno v:
Journal of Affective Disorders
Journal of Affective Disorders, 2022, 299 (S1), pp.335-343. ⟨10.1016/j.jad.2021.12.012⟩
Journal of Affective Disorders, 2022, 299 (S1), pp.335-343. ⟨10.1016/j.jad.2021.12.012⟩
International audience; Background: Pharmacological studies have yielded valuable insights into the role of the serotonin 4 receptor (HTR4) in major depressive episodes (MDE) and response to antidepressant drugs (AD). A genetic association has been s
Autor:
Khalil El Asmar, Céline Verstuyft, Bruno Fève, Emmanuel Haffen, Mircea Polosan, Emmanuelle Corruble, Bruno Falissard, Florian Ferreri, Séverine Trabado, Florence Gressier, Philippe Chanson, Romain Colle, Laurent Becquemont, Albane Vievard
Publikováno v:
Journal of Psychiatric Research. 107:120-127
Background Metabolic syndrome (MetS) is a major public health issue. We assessed whether early weight gain predicts later MetS in depressed patients treated with antidepressants. Methods In the 6-month prospective METADAP cohort, 260 non-overweight p
Autor:
Mircea Polosan, Florian Ferreri, Emmanuelle Corruble, Séverine Trabado, Philippe Chanson, Khalil El Asmar, Albane Vievard, Laurent Becquemont, Bruno Falissard, Romain Colle, Bruno Fève, Emmanuel Haffen, Céline Verstuyft, Florence Gressier
Publikováno v:
Journal of Affective Disorders. 241:22-28
Background Weight gain is a major side effect of antidepressant (AD) drugs. We assessed whether early weight gain is a predictor for long term weight gain in depressed patients treated with antidepressants. Methods In the six month prospective METADA
Autor:
Laurent Becquemont, Séverine Trabado, Emmanuelle Corruble, Bruno Fève, Emmanuel Haffen, Emanuel Loeb, Céline Verstuyft, Florian Ferreri, Mircea Polosan, Jean-François Costemale-Lacoste, Romain Colle, Séverine Martin, Khalil El Asmar
Publikováno v:
Journal of Affective Disorders. 240:230-236
Background 80–90% of patients with Major Depressive Episode (MDE) experience insomnia and up-to 50% severe insomnia. Glycogen Synthase Kinase-3β (GSK3B) is involved both in mood regulation and circadian rhythm. Since GSK3B polymorphisms could affe
Autor:
Séverine Martin, Bruno Fève, Delphine de Larminat, Emmanuelle Corruble, Emanuel Loeb, Khalil El Asmar, Laurent Becquemont, Eric Deflesselle, Adrien Rigal, Romain Colle, Séverine Trabado, Jean-François Costemale-Lacoste, Florence Gressier, Walid Choucha, Philippe Chanson, Céline Verstuyft
Publikováno v:
The Australian and New Zealand journal of psychiatry. 54(4)
Objective: Vascular endothelial growth factor A is a growth factor with pro-angiogenic and neurotrophic properties. Anti-vascular endothelial growth factor A treatments, used to treat cancers and opthalmic diseases, are known to induce depressive sym
Autor:
Bruno Fève, Laurent Becquemont, Florence Gressier, Romain Colle, Emmanuelle Corruble, Séverine Trabado, Kaïna Mahmoudi, Céline Verstuyft, Khalil El-Asmar, Abd El Kader Ait Tayeb
Publikováno v:
Basicclinical pharmacologytoxicologyREFERENCES. 126(3)
Two thirds of patients suffering from a major depressive episode (MDE) do not reach a complete response with antidepressant drugs. This lack of response is due to several factors, including genetic determinants. Since major depressive disorder is ass
Autor:
B. Feve, Denis J. David, Emmanuelle Corruble, Céline Verstuyft, Anne-Cécile Petit, Laurent Becquemont, Khalil El Asmar, Alain M. Gardier
Publikováno v:
Progress in Neuro-Psychopharmacology and Biological Psychiatry. 81:74-79
The study of genetic polymorphisms involved in antidepressants (AD) response is essential to provide a personalized medicine approach in the field of depression. β-arrestin 2 (ARRB2) is a candidate gene in the pharmacogenetics of AD as it is involve
Autor:
Céline Verstuyft, Khalil El Asmar, Albane Vievard, Emmanuelle Corruble, Bruno Fève, Laurent Becquemont, Romain Colle, Séverine Martin, Adrien Rigal
Publikováno v:
Psychological medicine. 49(14)
BackgroundThe brain-derived neurotrophic factor (BDNF) Val66Met polymorphism is associated with response to antidepressant drugs in depressed patients and with metabolic side effects after antipsychotic treatment. This study aims to assess the associ