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Autor:
Guy Garty, Oscar A. Padilla, Robyn D. Gartrell, Andrea Webster-Carrion, Masih Tazhibi, Hong-Jian Wei, Vilas Menon, Hanna Minns, Xu Zhang, Jovana Pavisic, Luca Szalontay, Peter Canoll, Marta Olah, Zhiguo Zhang, Raul Rabadan, Nicholas McQuillan, Stergios Zacharoulis, Claire Vanpouille-Box, Cheng-Chia Wu
Publikováno v:
Journal for ImmunoTherapy of Cancer. 9:A100-A100
BackgroundDiffuse intrinsic pontine gliomas (DIPG’s) are immunologically inert tumors with a median survival of 9–15 months. Radiation therapy (RT) is the mainstay treatment for DIPG but is associated with immunodepletion of the tumor microenviro