Zobrazeno 1 - 10
of 28
pro vyhledávání: 'Lüllmann-Rauch, Renate'
Autor:
Bernd Knöll, Renate Lüllmann-Rauch, Paul Saftig, Christian Haass, Yasuo Uchiyama, Wolfgang Wurst, Renate Wanner, Anja Capell, Rudi D'Hooge, Georg Werner, Stijn Stroobants, Patrick Lüningschrör, Benedikt Wefers, Daniela Sinske, Soichiro Kakuta, Michael Sendtner, Benjamin Dombert, Markus Damme
Publikováno v:
Cell Reports, Vol 30, Iss 10, Pp 3506-3519.e6 (2020)
Cell reports 30(10), 3506-3519.e6 (2020). doi:10.1016/j.celrep.2020.02.060
Cell reports 30(10), 3506-3519.e6 (2020). doi:10.1016/j.celrep.2020.02.060
Summary: Genetic variations in TMEM106B, coding for a lysosomal membrane protein, affect frontotemporal lobar degeneration (FTLD) in GRN- (coding for progranulin) and C9orf72-expansion carriers and might play a role in aging. To determine the physiol
Autor:
Julia Bär, Renate Lüllmann-Rauch, Mahmoud Bassal, André R. A. Marques, Lina Schmidt, Markus Damme, Markus Glatzel, Marina Mikhaylova, Niklas Thießen, Steffen E. Storck, Alessandro Di Spiezio, Udo Bartsch, Jens Fogh, Joachim Grötzinger, Paul Saftig, Claus U. Pietrzik
Publikováno v:
Autophagy
CTSD (cathepsin D) is one of the major lysosomal proteases indispensable for the maintenance of cellular proteostasis by turning over substrates of endocytosis, phagocytosis and autophagy. Consequently, CTSD deficiency leads to a strong impairment of
Autor:
Paul Saftig, Sönke Rudnik, Irm Hermans-Borgmeyer, Markus Glatzel, Thuy Linh Nguyen, Christian Bernreuther, Janna Schneppenheim, Bernd Schröder, Renate Lüllmann-Rauch
Publikováno v:
Oncotarget
// Thuy Linh Nguyen 1 , Janna Schneppenheim 2 , Sonke Rudnik 1 , Renate Lullmann-Rauch 2 , Christian Bernreuther 3 , Irm Hermans-Borgmeyer 4 , Markus Glatzel 3 , Paul Saftig 1 and Bernd Schroder 1 1 Biochemical Institute, Christian Albrechts Universi
Autor:
Marques, André R. A., Di Spiezio, Alessandro, Thießen, Niklas, Schmidt, Lina, Grötzinger, Joachim, Lüllmann-Rauch, Renate, Damme, Markus, Storck, Steffen E., Pietrzik, Claus U., Fogh, Jens, Bär, Julia, Mikhaylova, Marina, Glatzel, Markus, Bassal, Mahmoud, Bartsch, Udo, Saftig, Paul
Publikováno v:
Autophagy; May2020, Vol. 16 Issue 5, p811-825, 15p
Autor:
Sandra Kissing, Renate Lüllmann-Rauch, Albert Haas, Uwe Kornak, Eeva-Liisa Eskelinen, Paul Saftig, Sabrina Jabs, Jef K. De Brabander, Atsuhiro Ichihara, Sönke Rudnik, Jörg Heeren, Markus Damme
Publikováno v:
Autophagy, 13(4):670-685
The vacuolar-type H+-translocating ATPase (v-H+-ATPase) has been implicated in the amino acid-dependent activation of the mechanistic target of rapamycin complex 1 (MTORC1), an important regulator of macroautophagy. To reveal the mechanistic links be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb2812e53387bd2777d9f343a01c0fab
Autor:
Sandra Kissing, Bernd Schröder, Paul Saftig, Christian Grimm, Franz Bracher, Renate Lüllmann-Rauch, Oliver Griesbeck, Christian Wahl-Schott, Martin Biel, Markus Moser, Saskia Spahn, Simone Jörs, Bernd H. Northoff, Daniel Teupser, Jan Castonguay, Christian A. Luber, Christoph Müller, Cheng-Chang Chen, Hartmut Cuny, Lesca M. Holdt, Matthias Mann, Sami Hassan, Albert Haas, Christina Fendel, Norbert Klugbauer, Elisabeth Butz
Publikováno v:
Nature Communications. 5
Endolysosomal organelles play a key role in trafficking, breakdown and receptor-mediated recycling of different macromolecules such as low-density lipoprotein (LDL)-cholesterol, epithelial growth factor (EGF) or transferrin. Here we examine the role
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Publikováno v:
Graefe's Archive for Clinical and Experimental Ophthalmology. 239:788-793
A series of dicationic amphiphilic drugs, most of them immunomodulatory agents, are known to induce generalised lysosomal storage of sulphated glycosaminoglycans (GAGs) in rats and in cultured cells of several species including man. The present study
Publikováno v:
General Pharmacology: The Vascular System. 27:1317-1324
1. Certain compounds (e.g., the immunomodulator tilorone and congeners) are able to induce lysosomal storage of sulphated glycosaminoglycans (GAG), thus, producing cytological and biochemical alterations reminiscent of the inherited mucopolysaccharid