Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Xinxin Ding"'
Publikováno v:
Toxicol Sci
Previous studies have established that cytochrome P450 enzymes (CYPs) in both liver and lung are capable of bioactivating naphthalene (NA), an omnipresent air pollutant and possible human carcinogen, in vitro and in vivo. The aim of this study was to
Publikováno v:
Drug Metabolism and Disposition. 47:1469-1478
Previous studies using Cyp2abfgs-null (lacking all genes of the Cyp2a, 2b, 2f, 2g, and 2s subfamilies), CYP2A13/2F1-humanized, and liver-Cpr-null (LCN) mice showed that although hepatic cytochrome P450 (P450) enzymes are essential for systemic cleara
Autor:
Oliver Fiehn, Nathanial C. Stevens, Laura S. Van Winkle, Xinxin Ding, Lisa M. Tran, Patricia C. Edwards
Publikováno v:
Toxicological sciences : an official journal of the Society of Toxicology, vol 184, iss 2
Toxicol Sci
Toxicol Sci
Naphthalene is a ubiquitous environmental contaminant produced by combustion of fossil fuels and is a primary constituent of both mainstream and side stream tobacco smoke. Naphthalene elicits region-specific toxicity in airway club cells through cyto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9612ae4e68d4da297608a647dbc7e51
https://escholarship.org/uc/item/7n94c2cv
https://escholarship.org/uc/item/7n94c2cv
Publikováno v:
Drug Metab Dispos
Previous studies using Cyp2abfgs-null (lacking all genes of the Cyp2a, 2b, 2f, 2g, and 2s subfamilies), CYP2A13/2F1-humanized, and liver-Cpr-null (LCN) mice showed that although hepatic cytochrome P450 (P450) enzymes are essential for systemic cleara
Autor:
Xinxin Ding, Laura S. Van Winkle, Nicole M. Collette, Matthew Hartog, Bruce A. Buchholz, Edward A. Kuhn, Sarah A. Carratt
Publikováno v:
Toxicol Lett
Naphthalene (NA) is a ubiquitous environmental pollutant and possible human carcinogen that forms tumors in rodents with tissue/regional and species selectivity. This study seeks to determine whether NA is able to directly adduct DNA in an ex vivo cu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9122f9d767a96dbb5f24e9787e252ade
https://escholarship.org/uc/item/7w25m74s
https://escholarship.org/uc/item/7w25m74s
Publikováno v:
Toxicol Sci
Human exposure to naphthalene (NA), an acute lung toxicant and possible human carcinogen, is primarily through inhalation. Acute lung toxicity and carcinogenesis are thought to be related because the target sites for both are similar. To understand s
Autor:
Bruce A. Buchholz, Laura S. Van Winkle, Edward A. Kuhn, Sarah A. Carratt, Nicole M. Collette, Xinxin Ding
Naphthalene (NA) is a respiratory toxicant and possible human carcinogen. NA is a ubiquitous combustion product and significant component of jet fuel. The National Toxicology Program found that NA forms tumors in two species, in rats (nose) and mice
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d8fa403ab0c68f96df154124aa75106
https://escholarship.org/uc/item/90d4189p
https://escholarship.org/uc/item/90d4189p
Autor:
Laura S. Van Winkle, Liang Ding, Qing Yu Zhang, Weiguo Han, Pengfei Liu, Weizhu Yang, Nataliia Kovalchuk, Xinxin Ding
Publikováno v:
The FASEB Journal. 34:1-1
Publikováno v:
The FASEB Journal. 32
Publikováno v:
The FASEB Journal. 32