Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Madeleine Ennis"'
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 293:L69-L76
Proliferation of bronchial epithelial cells is an important biological process in physiological conditions and various lung diseases. The objective of this study was to determine how bronchial fibroblasts influence bronchial epithelial cell prolifera
Publikováno v:
Downey, D G, Brockbank, S, Martin, L, Ennis, M & Elborn, J 2007, ' The effect of treatment of cystic fibrosis pulmonary exacerbations on airways and systemic inflammation ' Pediatric Pulmonology, vol 42, no. 8, pp. 729-735 . DOI: 10.1002/ppul.20646
Background: Chronic infection in cystic fibrosis (CF) and airway inflammation leads to progressive lung injury Neutrophils are considered to be responsible for the onset and promotion of the inflammatory response within the CF lung. The relationship
Autor:
Alex Horsley, Stephen Rowan, J. Stuart Elborn, Madeleine Ennis, Ian Bradbury, T. Lynch, Per E. Gustafsson, Judy Bradley, Katherine O'Neill, John Lawson
Publikováno v:
American journal of respiratory and critical care medicine. 189(5)
In bronchiectasis there is a need for improved markers of lung function to determine disease severity and response to therapy.To assess whether the lung clearance index is a repeatable and more sensitive indicator of computed tomography (CT) scan abn
Autor:
Madeleine Ennis, Richard C. Boucher, J. Stuart Elborn, Lan Wei, Erich Klem, Gisli G. Einarsson, Matthew C. Wolfgang, Maire Drain, Christopher Cardwell, Michael M. Tunney
Publikováno v:
American journal of respiratory and critical care medicine. 187(10)
Characterization of bacterial populations in infectious respiratory diseases will provide improved understanding of the relationship between the lung microbiota, disease pathogenesis, and treatment outcomes.To comprehensively define lung microbiota c
Publikováno v:
Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society. 11(4)
Background Neutrophil elastase (NE)-mediated inflammation contributes to lung damage in cystic fibrosis (CF). We investigated if DX-890, a small-protein NE inhibitor, could reduce neutrophil trans-epithelial migration and reduce activity released fro
Autor:
Ian Bradbury, Joseph Elborn, Richard I. Davis, Dean Andrew Fennell, Peter W. Hamilton, Madeleine Ennis, Nicholas David Magee, James Beattie, Chris Carland, John J. McGarvey, Kieran McManus
Publikováno v:
Journal of biomedical optics. 15(2)
The main curative therapy for patients with nonsmall cell lung cancer is surgery. Despite this, the survival rate is only 50%, therefore it is important to more efficiently diagnose and predict prognosis for lung cancer patients. Raman spectroscopy i
Publikováno v:
Journal of Applied Physiology. 71:2499-2506
Intravascular application of goat anti-rabbit immunoglobulin E (IgE) was used to stimulate parenchymal mast cells in situ in perfused rabbit lungs. Sustained pulmonary arterial pressure rise was evoked in the absence of lung vascular permeability inc
Publikováno v:
International Archives of Allergy and Immunology. 92:203-208
Intravascular application of radiographic contrast media (RCM) can cause adverse allergic/pseudoallergic reactions in certain individuals. In view of the increased risk for the reactions associated with cardiovascular diseases, we have investigated h
Autor:
Bettina C. Schock, John J. McGarvey, Fred Possmayer, Lindsay J. Barrett, Madeleine Ennis, S. Gilchrist, J. Renwick Beattie, J. Stuart Elborn, Carroll E. Cross, Ciaran Maguire, W. James Curry
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 21(3)
Alpha-tocopherol (aT), the predominant form of vitamin E in mammals, is thought to prevent oxidation of polyunsaturated fatty acids. In the lung, aT is perceived to be accumulated in alveolar type II cells and secreted together with surfactant into t
Publikováno v:
Inflammation Research. 53
Drug-induced adverse reactions can be allergic or pseudoallergic in nature, in this study the histamine releasing ability of 4 radiographic contrast media and 2 opioid analgesics was tested on a variety of mast cell containing cell suspensions.Mast c