Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Ayaka Ito"'
Autor:
Aldons J. Lusis, Antonio Castrillo, Xiaohui Wu, Jaspreet S. Sandhu, Bence Daniel, Xin Liu, Kevin Qian, Zhengyi Zhang, Brandon J. Thomas, Stephen T. Smale, Prashant Rajbhandari, Marius Jones, David Salisbury, Julian P. Whitelegge, Cynthia Hong, Ascia Eskin, Laszlo Nagy, Tamer Sallam, Ayaka Ito, David Casero, Peter Tontonoz, Thomas Gilliland, Mete Civelek
Publikováno v:
Nature medicine, vol 24, iss 3
Digital.CSIC. Repositorio Institucional del CSIC
instname
Digital.CSIC. Repositorio Institucional del CSIC
instname
Nuclear receptors regulate gene expression in response to environmental cues, but the molecular events governing the cell-type specificity of nuclear receptors remain poorly understood. Here we outline a role for a non-coding RNA in modulating the ce
Autor:
Anna Wilkinson, Yoko Shimizu, Jianjia Fan, Edie Dullaghan, Liisa A.M. Galea, Ayaka Ito, Cheryl L. Wellington, Jeniffer Chan, Peter Tontonoz, Tom A. Pfeifer
Publikováno v:
Journal of Lipid Research, Vol 54, Iss 11, Pp 3139-3150 (2013)
Journal of lipid research, vol 54, iss 11
Journal of lipid research, vol 54, iss 11
Apolipoprotein E (apoE) is the major lipid carrier in the central nervous system. As apoE plays a major role in the pathogenesis of Alzheimer disease (AD) and also mediates repair pathways after several forms of acute brain injury, modulating the exp
Autor:
Ayaka, Ito, Cynthia, Hong, Kazuhiro, Oka, Jon V, Salazar, Cody, Diehl, Joseph L, Witztum, Mercedes, Diaz, Antonio, Castrillo, Steven J, Bensinger, Lawrence, Chan, Peter, Tontonoz
Publikováno v:
Immunity. 45(6)
Liver X receptors (LXRs) are regulators of cholesterol metabolism that also modulate immune responses. Inactivation of LXR α and β in mice leads to autoimmunity; however, how the regulation of cholesterol metabolism contributes to autoimmunity is u
Autor:
Antonio Castrillo, Peter Tontonoz, Mercedes Diaz, Steven J. Bensinger, Joseph L. Witztum, Ayaka Ito, Kazuhiro Oka, Cody J. Diehl, Cynthia Hong, Lawrence Chan, Jon Salazar
Publikováno v:
Immunity, vol 45, iss 6
Digital.CSIC. Repositorio Institucional del CSIC
instname
Digital.CSIC. Repositorio Institucional del CSIC
instname
Liver X receptors (LXRs) are regulators of cholesterol metabolism that also modulate immune responses. Inactivation of LXR α and β in mice leads to autoimmunity; however, how the regulation of cholesterol metabolism contributes to autoimmunity is u
Autor:
Per Niklas Hedde, Enrico Gratton, Ayaka Ito, Xuewei Zhu, Peter Tontonoz, Elizabeth J. Tarling, Cynthia Hong, Xin Rong, John S. Parks
Publikováno v:
eLife
Ito, A; Hong, C; Rong, X; Zhu, X; Tarling, EJ; Hedde, PN; et al.(2015). LXRs link metabolism to inflammation through Abca1-dependent regulation of membrane composition and TLR signaling. eLife, 4(JULY 2015). doi: 10.7554/eLife.08009. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/7nv0d563
eLife, Vol 4 (2015)
Ito, A; Hong, C; Rong, X; Zhu, X; Tarling, EJ; Hedde, PN; et al.(2015). LXRs link metabolism to inflammation through Abca1-dependent regulation of membrane composition and TLR signaling. eLife, 4(JULY 2015). doi: 10.7554/eLife.08009. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/7nv0d563
eLife, Vol 4 (2015)
The liver X receptors (LXRs) are transcriptional regulators of lipid homeostasis that also have potent anti-inflammatory effects. The molecular basis for their anti-inflammatory effects is incompletely understood, but has been proposed to involve the
Autor:
Xin Rong, Michael E. Jung, Caroline M. W. van Stijn, Grace L. Su, Jason K. Kim, Marius Jones, Tamer Sallam, Cynthia Hong, Ayaka Ito, Thomas Gilliland, Xiaohui Wu, Lily C. Chao, Brian T. Chamberlain, Rajendra K. Tangirala, Peter Tontonoz
Publikováno v:
Journal of lipid research, vol 55, iss 6
Journal of Lipid Research, Vol 55, Iss 6, Pp 1120-1130 (2014)
Journal of Lipid Research, Vol 55, Iss 6, Pp 1120-1130 (2014)
The liver X receptors (LXRs) are members of the nuclear receptor superfamily that regulate sterol metabolism and inflammation. We sought to identify previously unknown genes regulated by LXRs in macrophages and to determine their contribution to athe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11553028366aa10722f6f7a3fd72a772
https://europepmc.org/articles/PMC4031943/
https://europepmc.org/articles/PMC4031943/
Autor:
Michael E. Jung, Xin Rong, David A. Ford, Elizabeth J. Tarling, Peter A. Edwards, Carolyn J. Albert, Bo Wang, Cynthia Hong, Ayaka Ito, Peter Tontonoz, Brian T. Chamberlain, Mark A. Duerr, Jie Gao
Publikováno v:
Cell metabolism, vol 18, iss 5
SummaryThe fatty acyl composition of phospholipids determines the biophysical character of membranes and impacts the function of membrane proteins. Here, we define a nuclear receptor pathway for the dynamic modulation of membrane composition in respo
Autor:
Steven J. Bensinger, Peter Tontonoz, Xin Rong, Tram Phung, Katrin Ericson, Philip L. Cohen, Cynthia Hong, Ayaka Ito, Lloyd S. Miller, Hanna K. A. Mikkola, Wen-Hai Shao, Noelia A-Gonzalez, Yoko Kidani, Antonio Castrillo, Simon W. Beaven
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
instname
et al.
The most abundant immune cell type is the neutrophil, a key first responder after pathogen invasion. Neutrophil numbers in the periphery are tightly regulated to prevent opportunistic infections and aberrant inflammation. In healthy indiv
The most abundant immune cell type is the neutrophil, a key first responder after pathogen invasion. Neutrophil numbers in the periphery are tightly regulated to prevent opportunistic infections and aberrant inflammation. In healthy indiv