Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Anna Mae Diehl"'
Autor:
Arun J. Sanyal, Stephen A. Williams, Joel E. Lavine, Brent A. Neuschwander-Tetri, Leigh Alexander, Rachel Ostroff, Hannah Biegel, Kris V. Kowdley, Naga Chalasani, Srinivasan Dasarathy, Anna Mae Diehl, Rohit Loomba, Bilal Hameed, Cynthia Behling, David E. Kleiner, Saul J. Karpen, Jessica Williams, Yi Jia, Katherine P. Yates, James Tonascia
Publikováno v:
Journal of hepatology, vol 78, iss 4
J Hepatol
J Hepatol
There is an unmet need for development of non-invasive tests for the diagnostic assessment and monitoring of nonalcoholic fatty liver disease (NAFLD).Using modified-aptamer proteomics, we assayed 5220 proteins in each of 2852 single serum samples fro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b98d930021ee18e344ed6b8fc32118b5
https://escholarship.org/uc/item/0d9809np
https://escholarship.org/uc/item/0d9809np
Autor:
Tianyi Chen, Jeongeun Hyun, Ali Ahmadi, Hidekazu Tsukamoto, Zhaoli Sun, Kuo Du, Ullas V. Chembazhi, Anna Mae Diehl, Ivan Rusyn, Sushant Bangru, Auinash Kalsotra
Publikováno v:
J Clin Invest
Severe alcoholic hepatitis (SAH) is a deadly liver disease without an effective medical therapy. Although SAH mortality is known to correlate with hepatic accumulation of immature liver cells, why this occurs and how it causes death are unclear. Here
Publikováno v:
Nature Metabolism. 1:1027-1029
Nonalcoholic fatty liver disease (NAFLD) has emerged as the most prevalent liver disease worldwide, mainly because of the massive parallel global increase in obesity. Extensive public-health and political efforts will be needed in the near future to
Autor:
Anna Mae Diehl, Nezam H. Afdhal, Andrew J. Muir, Jaime Bosch, G. Mani Subramanian, Zachary Goodman, Raul Aguilar Schall, Arun J. Sanyal, Stephen A. Harrison, Stephen H. Caldwell, B. Mccolgan, Maria Stepanova, Manal F. Abdelmalek, Robert P. Myers, Vlad Ratziu, Zobair M. Younossi, Mitchell L. Shiffman
Publikováno v:
Journal of Hepatology. 69:1365-1370
Although patients with cryptogenic cirrhosis have historically been considered as having "burnt-out" non-alcoholic steatohepatitis (NASH), some controversy remains. The aim of this study was to compare outcomes of patients with cryptogenic cirrhosis
Autor:
Cynthia D. Guy, Claire Faulkner, Manal F. Abdelmalek, Larry Mimms, Ranjan Sudan, Anna Mae Diehl, Anjali Jain, Xiao-jun Li, Lauren Okada, Dana Portenier, S Singh, Lisa Richards, Rohit Loomba, Kelly D. Hester
Publikováno v:
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, vol 17, iss 9
Background & Aims We analyzed markers of fibrosis in serum samples from patients with nonalcoholic fatty liver disease (NAFLD), assessed by liver biopsy. We used serum levels of markers to develop an algorithm to discriminate patients with advanced f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b31f3804628ef5863ad3bbb749e54907
https://escholarship.org/uc/item/0b04137v
https://escholarship.org/uc/item/0b04137v
Publikováno v:
Critical Reviews in Biochemistry and Molecular Biology. 53:264-278
Nonalcoholic fatty liver disease (NAFLD) encompasses a spectrum of obesity-associated liver diseases and it has become the major cause of cirrhosis in the Western world. The high prevalence of NAFLD-associated advanced liver disease reflects both the
Publikováno v:
Journal of Hepatology. 68:550-562
Liver disease remains a leading cause of mortality worldwide despite recent successes in the field of viral hepatitis, because increases in alcohol consumption and obesity are fuelling an epidemic of chronic fatty liver disease for which there are cu
Autor:
Hays Arnold, Robert P. Myers, Saumya Jayakumar, C. Stephen Djedjos, Michael Charlton, Michael S. Middleton, Magdy Elkhashab, Manal F. Abdelmalek, Parvez S. Mantry, Anna Mae Diehl, Ren Xu, Stephen H. Caldwell, Nezam H. Afdhal, Ling Han, Reem Ghalib, Claude B. Sirlin, Kris V. Kowdley, Rohit Loomba, Eric Lawitz, Zachary Goodman, G. Mani Subramanian
Publikováno v:
Journal of hepatology, vol 70, iss 1
Jayakumar, Saumya; Middleton, Michael S; Lawitz, Eric J; Mantry, Parvez S; Caldwell, Stephen H; Arnold, Hays; et al.(2019). Longitudinal correlations between MRE, MRI-PDFF, and liver histology in patients with non-alcoholic steatohepatitis: Analysis of data from a phase II trial of selonsertib. JOURNAL OF HEPATOLOGY, 70(1), 133-141. doi: 10.1016/j.jhep.2018.09.024. UC San Diego: Retrieved from: http://www.escholarship.org/uc/item/96b1p0vj
Jayakumar, Saumya; Middleton, Michael S; Lawitz, Eric J; Mantry, Parvez S; Caldwell, Stephen H; Arnold, Hays; et al.(2019). Longitudinal correlations between MRE, MRI-PDFF, and liver histology in patients with non-alcoholic steatohepatitis: Analysis of data from a phase II trial of selonsertib. JOURNAL OF HEPATOLOGY, 70(1), 133-141. doi: 10.1016/j.jhep.2018.09.024. UC San Diego: Retrieved from: http://www.escholarship.org/uc/item/96b1p0vj
Background & Aims Non-invasive tools for monitoring treatment response and disease progression in non-alcoholic steatohepatitis (NASH) are needed. Our objective was to evaluate the utility of magnetic resonance (MR)-based hepatic imaging measures for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da08a6210691f138234a9000638dd431
https://escholarship.org/uc/item/96b1p0vj
https://escholarship.org/uc/item/96b1p0vj
Autor:
Richard T. Premont, Mariana Verdelho Machado, Thiago A. Pereira, Anna Mae Diehl, Guanhua Xie, Helena Cortez-Pinto, Gregory A. Michelotti
Publikováno v:
Journal of Hepatology. 63:962-970
Background & Aims Mechanisms that regulate regeneration of injured livers are complex. YAP, a stem cell associated factor, controls liver growth in healthy adult mice. Increasing nuclear localization of YAP triggers accumulation of reactive-appearing
Autor:
Guido Ferrari, Audrey Lan, Marzena Swiderska-Syn, Susanna Naggie, Anna Mae Diehl, Sam Lusk, Wing-Kin Syn, Cynthia D. Guy, Steve S. Choi
Publikováno v:
Open Forum Infectious Diseases
Liver disease is a leading cause of HIV-related mortality. Hepatitis C virus (HCV)–related fibrogenesis is accelerated in the setting of HIV coinfection, yet the mechanisms underlying this aggressive pathogenesis are unclear. We identified formalin