Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Xiaofeng Tian"'
Autor:
Yan H; 1Department of Pharmacology, Dalian Medical University, Dalian, China. 2Department of Pharmacy, Second Affiliated Hospital of Dalian Medical University, Dalian, China. 3Department of General Surgery, Second Affiliated Hospital of Dalian Medical University, Dalian, China., Jihong Y, Feng Z, Xiaomei X, Xiaohan Z, Guangzhi W, Zhenhai M, Dongyan G, Xiaochi M, Qing F, Kexin L, Xiaofeng T
Publikováno v:
Critical care medicine [Crit Care Med] 2014 May; Vol. 42 (5), pp. e373-81.
Autor:
Yue Wang, Yan Zhao, Zhecheng Wang, Ruimin Sun, Boyang Zou, Ruixi Li, Deshun Liu, Musen Lin, Junjun Zhou, Shili Ning, Xiaofeng Tian, Jihong Yao
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Frontiers in Immunology
Frontiers in Immunology
Pyroptosis is a newly discovered form of cell death. Peroxiredoxin 3 (PRX3) plays a crucial role in scavenging reactive oxygen species (ROS), but its hepatoprotective capacity in acetaminophen (APAP)-induced liver disease remains unclear. The aim of
Autor:
Junjun Zhou, Yan Zhao, Ruimin Sun, Jihong Yao, Dongcheng Feng, Rong Fu, Xiaofeng Tian, Zhecheng Wang, Ruiwen Wang, Li Lv
Publikováno v:
Oxidative Medicine and Cellular Longevity, Vol 2019 (2019)
Oxidative Medicine and Cellular Longevity
Oxidative Medicine and Cellular Longevity
Alcohol abuse has become common worldwide and has been recognized as a major cause of chronic alcoholic liver disease (ALD). ALD encompasses a complex process that includes a broad scope of hepatic lesions, ranging from steatosis to cirrhosis. In par
Autor:
Yan Zhao, Yu Sun, Huanyu Zhao, Zhecheng Wang, Yunfei Geng, Meiyang Zhu, Ruimin Sun, Jihong Yao, Xiaofeng Tian, Xiaohui Kang, Yue Wang, Yan Hu
Publikováno v:
Toxicology and Applied Pharmacology. 432:115758
Mitochondrial dysfunction is a major factor in nonalcoholic fatty liver disease (NAFLD), preceding insulin resistance and hepatic steatosis. Carnosol (CAR) is a kind of diterpenoid with antioxidant, anti-inflammatory and antitumor activities. Peroxir
Autor:
Junjun Zhou, Yang Li, Zhecheng Wang, Ruimin Sun, Yan Zhao, Jihong Yao, Xiaohui Kang, Rong Fu, Zhanyu Wang, Yan Hu, Ruiwen Wang, Xiaofeng Tian, Wen Shan
Publikováno v:
Br J Pharmacol
Background and purpose Hepatic fatty acid metabolism disorder, a key pathogenic mechanism underlying non-alcoholic fatty liver disease (NAFLD), is associated with the hyperacetylation of mitochondrial enzymes. Acyl-CoA synthetase family member 3 (ACS
Autor:
Junjun Zhou, Zhao Chen, Guangzhi Wang, Dongcheng Feng, Yan Hu, Jihong Yao, Yan Zhao, Zhecheng Wang, Xiaofeng Tian, Xiaodong Ma, Yang Li, Feng Zhang
Publikováno v:
Toxicology and Applied Pharmacology. 403:115125
Epithelial-mesenchymal transition (EMT) is regulated by reactive oxygen species (ROS) in liver fibrosis. p66Shc is a redox enzyme, but its role of EMT is unclear in liver fibrosis. Long noncoding RNAs (lncRNAs) have been implicated as important regul
Autor:
Yang Lu, Yan Hu, Huirong Jing, Xiaohan Zhai, Yuan Lin, Wei Xu, Xiaofeng Tian, Dongyan Gao, Mingzhu Li, Jihong Yao
Publikováno v:
Toxicology Letters. 228:67-74
Salvianolic acid B (SalB) is isolated from the traditional Chinese medical herb salvia miltiorrhiza. It has many biological and pharmaceutical activities. This study aimed to investigate the effect of SalB on acute ethanol-induced hepatic injury in r
Autor:
Chunchun Ding, Yan Zhao, Junjun Zhou, Zhenlu Li, Xue Shi, Dongyan Gao, Li Lv, Ning Zhang, Jihong Yao, Guo Zu, Xiaofeng Tian
Publikováno v:
Scientific Reports
Salvianolic acid A (SalA), one of the most efficacious polyphenol compounds extracted from Radix Salvia miltiorrhiza (Danshen), has been shown to possess many potential pharmacological activities. This study aimed to investigate whether SalA has hepa
Autor:
Guangzhi Wang, Kexin Liu, Lili Gao, Chunchun Ding, Jihong Yao, Wen Shan, Yan Zhao, Feng Zhang, Wenjing Zeng, Xiaofeng Tian, Xue Shi, Yan Hu, Ning Zhang
Publikováno v:
Molecular nutritionfood research. 60(9)
cope Carnosic acid (CA), which is extracted from rosemary, displays multiple pharmacological activities. This study aimed to investigate the effects of CA on chronic alcoholic liver injury and to elucidate the related mechanisms. Methods and results
Autor:
Xiaochi Ma, Lili Gao, Jihong Yao, Wenjing Zeng, Zhenlu Li, Wei Xu, Jinyong Peng, Ning Zhang, Yan Hu, Wen Shan, Xiaofeng Tian, Guangzhi Wang, Dongyan Gao
Publikováno v:
Scientific Reports
The inflammatory mediator high-mobility group box 1 (HMGB1) plays a critical role in the pathogenesis of non-alcoholic fatty liver disease (NAFLD). However, the regulation of HMGB1 in NAFLD, particularly through sirtuin 1 (SIRT1), remains unclear. In