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pro vyhledávání: '"Martín, Hugo"'
Autor:
José Pedro Castro, André Kleinridders, Kerstin Nowotny, Tobias Jung, Tilman Grune, Raquel Fernando, Martín Hugo, Kristina Wardelmann
Publikováno v:
Free Radical Biology and Medicine. 108:S35
The white adipose tissue (WAT) is crucial for maintaining metabolism homeostasis by storing lipids and/or by secreting adipokines. A healthy WAT relies on continuous renewal, through a multi-step process called adipogenesis. Upon failure, the risk fo
Publikováno v:
Free Radical Biology and Medicine. 108:S95
Type 2 diabetes is a chronic metabolic disorder characterized, among other features, by elevated levels of circulatory free fatty acids. Several studies in animal and cellular models indicate that increased accumulation of lipids leads to oxidative a
Autor:
Leticia Prates Roma, Tilman Grune, Antonio Martínez-Ruiz, Martín Hugo, Carmen García, Ioana Korovila, Anabel Marina
Publikováno v:
Free Radical Biology and Medicine. 108:S100
The main machinery responsible for cellular protein maintenance is the ubiquitin-proteasomal system. The main task of the system is a fast and efficient degradation of proteins not needed anymore in cellular metabolism. It is accepted that upon oxida