Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Karine Andrieux"'
Autor:
Louise Fliedel, Khair Alhareth, Johanne Seguin, Marwa El-Khashab, Audrey Chissey, Nathalie Mignet, Thierry Fournier, Karine Andrieux
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 11, p 6299 (2022)
Pregnant women are still considered as drug orphans. Developing new medications for pregnancy complications is an urgent need. Nanomedicines seem to be a promising approach to control the biodistribution of drugs to ensure both the mother’s and the
Externí odkaz:
https://doaj.org/article/9988cd9ec7284888b4bf4e5959785e6c
Autor:
Morgane Renault-Mahieux, Victoire Vieillard, Johanne Seguin, Philippe Espeau, Dang Tri Le, René Lai-Kuen, Nathalie Mignet, Muriel Paul, Karine Andrieux
Publikováno v:
Pharmaceutics, Vol 13, Iss 7, p 970 (2021)
(1) Background: Glioblastoma (GBM) is the most frequent cerebral tumor. It almost always relapses and there is no validated treatment for second-line GBM. We proposed the coencapsulation of fisetin and cisplatin into liposomes, aiming to (i) obtain a
Externí odkaz:
https://doaj.org/article/5aaaee7781b34eb0bb2cb81014ea6d34
Autor:
Lucie Valero, Khair Alhareth, Jenifer Espinoza Romero, Warren Viricel, Jeanne Leblond, Audrey Chissey, Hélène Dhotel, Caroline Roques, Danielle Campiol Arruda, Virginie Escriou, Nathalie Mignet, Thierry Fournier, Karine Andrieux
Publikováno v:
Molecules, Vol 23, Iss 5, p 1085 (2018)
Nanomedicine as a therapeutic approach for pregnancy-related diseases could offer improved treatments for the mother while avoiding side effects for the fetus. In this study, we evaluated the potential of liposomes as carriers for small interfering R
Externí odkaz:
https://doaj.org/article/35e7ec9186e647339cdfbc0fcd711722
Autor:
René Rebollo, Feras Oyoun, Yohann Corvis, Mazen M. El-Hammadi, Bruno Saubamea, Karine Andrieux, Nathalie Mignet, Khair Alhareth
Publikováno v:
ACS Applied Materials & Interfaces. 14:39736-39745
Liposomes constitute the most exploited drug-nanocarrier with several liposomal drugs on the market. Microfluidic-based preparation methods stand up as a promising approach with high reproducibility and the ability to scale up. In this study, liposom
Autor:
Sophie Gil, Christelle Simasotchi, Karine Andrieux, Khair Alhareth, Thierry Fournier, Lucie Valero, Nathalie Mignet, Daniel Scherman, Caroline Roques
Publikováno v:
International Journal of Pharmaceutics
International Journal of Pharmaceutics, Elsevier, 2017, 532 (2), pp.729-737. ⟨10.1016/j.ijpharm.2017.07.076⟩
International Journal of Pharmaceutics, Elsevier, 2017, 532 (2), pp.729-737. ⟨10.1016/j.ijpharm.2017.07.076⟩
Uptake and passage of nanocarriers through the placenta are critical information to develop new therapeutic approaches during pregnancy. In order to assess nanocarriers transplacental passage and penetration into the placenta, we studied and optimize
Publikováno v:
International Journal of Pharmaceutics. 605:120772
Microfluidization has been investigated as a new, scalable, and basic component saving method to produce cationic lipid nanoparticles, in particular for the delivery of short interfering RNAs (siRNAs). The design of experiment (DoE) allowed to reach
Autor:
Thierry Fournier, Louise Fliedel, Karine Andrieux, Khair Alhareth, Nathalie Mignet, Khaled Elhady Mohamed, Lucie Valero, Sophie Gil, Caroline Roques
Publikováno v:
International Journal of Pharmaceutics. 567:118479
Controlled distribution of a drug by its association to a nanocarrier is a promising approach for the treatment of pregnancy disorders such as preeclampsia. For this application, tracking both the nanocarrier and the drug is necessary to ensure the s
Autor:
Claudie Bourgaux, Muriel Lalanne, Michel Ollivon, Didier Desmaële, M. Ré, Madeleine Besnard, Angelo Paci, Karine Andrieux, Patrick Couvreur
Publikováno v:
International Journal of Pharmaceutics. 344:62-70
Didanosine is a polar drug with poor membrane absorption and high hepatic first pass metabolism. This study aimed at developing a lipidic formulation of a glycerolipidic prodrug of didanosine in order to improve its bioavailability. In the course of
Autor:
Laura Forte, Cécile Grabielle-Madelmont, Sylviane Lesieur, Maïté Paternostre, Karine Andrieux, Michel Ollivon
Publikováno v:
Pharmaceutical Research. 21:1505-1516
To get a continuous description of the insertion and partition processes of sodium taurocholate (TC) into the lipid bilayers of vesicles that can serve as a model for understanding the mechanism of destabilization by the bile salts of liposomes used
Publikováno v:
Journal of Chromatography B: Biomedical Sciences and Applications. 706:141-147
A methodology based on high-performance gel exclusion chromatography (HPLC-GEC) has been developed to perform permeability studies of vesicles. Encapsulation of two marker isothiocyanate fluorescein (FITC) dextrans of 4400 and 40,500 molecular mass w