Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Zhimin Yin"'
Publikováno v:
Redox Biology, Vol 20, Iss, Pp 157-166 (2019)
Redox Biology
Redox Biology
Sepsis is a life-threatening organ dysfunction caused by dysregulated host response to infection and characterized by redox imbalance and severe oxidative stress. Glutathione (GSH) serves several vital functions, including scavenging free radicals an
Autor:
Baolin Jiang, Jinyi Zhou, Juanjuan Liang, Xiaowen Bi, Lan Luo, Xirui Fan, Zhimin Yin, Xintong Yan
Publikováno v:
Frontiers in Immunology, Vol 11 (2021)
Frontiers in Immunology
Frontiers in Immunology
CREB binding protein (CBP), a transcriptional coactivator and acetyltransferase, is involved in the pathogenesis of inflammation-related diseases. High mobility group box-1 protein (HMGB1) is a critical mediator of lethal sepsis, which has prompted i
Publikováno v:
Inflammation Research. 66:579-589
Here, we used various approaches to investigate the suppressive role of daphnetin in LPS-induced inflammatory response, with the goal to understand the underlining molecular mechanism by which daphnetin regulated these processes. We examined the surv
Publikováno v:
Inflammation. 42(5)
The aims of this study were to investigate the effect of Hsp27 on LPS-induced inflammation and identify the precise mechanisms about how Hsp27 regulates LPS-induced TLR4 signaling in Thp1 cells. Thp1 cells were transfected with Flag-Hsp27 or pcDNA3.1
Autor:
Yi Zhou, Xiang Cao, Yang Yang, Jing Wang, Weidong Yang, Peiling Ben, Lei Shen, Peng Cao, Lan Luo, Zhimin Yin
Publikováno v:
Frontiers in Immunology
Frontiers in Immunology, Vol 9 (2018)
Frontiers in Immunology, Vol 9 (2018)
Glutathione S-transferase Pi (GSTP) was originally identified as one of cytosolic phase II detoxification enzymes and also was considered to function via its non-catalytic, ligand-binding activity. We have reported that GSTP played an anti-inflammato
Publikováno v:
International immunopharmacology. 48
Bergapten (BG) is a cumarine-derivate compound in many medicinal plants. Here, in vitro and in vivo experimental results indicated that BG possesses anti-inflammatory properties, Based on this, we further investigated the precise molecular mechanisms
Publikováno v:
Inflammation Research. 63:597-608
Forsythin (FOR) is an active ingredient extracted from the fruit of the medicinal plant Forsythia suspensa (Thunb.) Vahl. Here, we investigated the effect of FOR on LPS-induced inflammatory response and the underlying molecular mechanisms in RAW264.7
Autor:
Yanhong Gao, Junhong Liu, Peiling Ben, Huang Huang, Yimiao Xu, Jin Fu, Changyan Lu, Yinqiang Xin, Zhimin Yin, Zhengping Zhang, Lan Luo
Publikováno v:
International Immunopharmacology. 11:179-186
Curcumin, a natural polyphenolic compound, has been reported to possess anti-inflammatory properties. Previous works showed that curcumin decreased lipopolysaccharide (LPS)-induced iNOS up-regulation at transcription level. However, whether curcumin
Protective effects of chlorogenic acid on acute hepatotoxicity induced by lipopolysaccharide in mice
Publikováno v:
Inflammation Research. 59:871-877
To investigate the potential protective effects of chlorogenic acid (CGA) on acute liver injury caused by lipopolysaccharide (LPS) in mice.C57BL/6J mice were pretreated with CGA (50 mg/kg, intraperitoneally) once per day for 5 days before an overnigh
Autor:
Yinqiang Xin, Suli Hong, Guilan Li, Jin Fu, Zhimin Yin, Zhiyong Feng, Lan Luo, Junhong Liu, Chao Zhang, Qi Wang
Publikováno v:
Cellular Immunology. 264:127-134
HSP27 is a member of the small HSP family which has been linked to different signaling pathways regulating critical cellular functions. But the role of HSP27 in LPS-induced inflammatory signaling pathways is still unclear. In the present study, both