Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Holmen, Oddgeir"'
Autor:
Justice AE; Department of Epidemiology, University of North Carolina, Chapel Hill, NC, USA.; Weis Center for Research, Geisinger Health System, Danville, PA, USA., Karaderi T; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.; Department of Biological Sciences, Faculty of Arts and Sciences, Eastern Mediterranean University, Famagusta, Cyprus., Highland HM; Department of Epidemiology, University of North Carolina, Chapel Hill, NC, USA.; Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX, USA., Young KL; Department of Epidemiology, University of North Carolina, Chapel Hill, NC, USA., Graff M; Department of Epidemiology, University of North Carolina, Chapel Hill, NC, USA., Lu Y; Division of Epidemiology, Department of Medicine, Vanderbilt-Ingram Cancer Center, Vanderbilt Epidemiology Center, Vanderbilt University School of Medicine, Nashville, TN, USA.; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; The Genetics of Obesity and Related Metabolic Traits Program, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Turcot V; Montreal Heart Institute, Universite de Montreal, Montreal, Quebec, Canada., Auer PL; Zilber School of Public Health, University of Wisconsin-Milwaukee, Milwaukee, WI, USA., Fine RS; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Genetics, Harvard Medical School, Boston, MA, USA.; Division of Endocrinology and Center for Basic and Translational Obesity Research, Boston Children's Hospital, Boston, MA, USA., Guo X; Institute for Translational Genomics and Population Sciences, LABioMed at Harbor-UCLA Medical Center, Torrance, CA, USA., Schurmann C; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; The Genetics of Obesity and Related Metabolic Traits Program, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Lempradl A; Max Planck Institute of Immunobiology and Epigenetics, Freiburg, Germany., Marouli E; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK., Mahajan A; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK., Winkler TW; Department of Genetic Epidemiology, University of Regensburg, Regensburg, Germany., Locke AE; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA.; McDonnell Genome Institute, Washington University School of Medicine, Saint Louis, MO, USA., Medina-Gomez C; Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands.; Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands., Esko T; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Division of Endocrinology and Center for Basic and Translational Obesity Research, Boston Children's Hospital, Boston, MA, USA.; Estonian Genome Center, University of Tartu, Tartu, Estonia., Vedantam S; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Genetics, Harvard Medical School, Boston, MA, USA.; Division of Endocrinology and Center for Basic and Translational Obesity Research, Boston Children's Hospital, Boston, MA, USA., Giri A; Department of Obstetrics and Gynecology, Institute for Medicine and Public Health, Vanderbilt Genetics Institute, Vanderbilt University, Nashville, TN, USA., Lo KS; Montreal Heart Institute, Universite de Montreal, Montreal, Quebec, Canada.; Department of Obstetrics and Gynecology, Institute for Medicine and Public Health, Vanderbilt Genetics Institute, Vanderbilt University, Nashville, TN, USA., Alfred T; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Mudgal P; Center for Diabetes Research, Wake Forest School of Medicine, Winston-Salem, NC, USA., Ng MCY; Center for Diabetes Research, Wake Forest School of Medicine, Winston-Salem, NC, USA.; Center for Genomics and Personalized Medicine Research, Wake Forest School of Medicine, Winston-Salem, NC, USA., Heard-Costa NL; Department of Neurology, Boston University School of Medicine, Boston, MA, USA.; NHLBI Framingham Heart Study, Framingham, MA, USA., Feitosa MF; Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St. Louis, MO, USA., Manning AK; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Medicine, Harvard University Medical School, Boston, MA, USA.; Massachusetts General Hospital, Boston, MA, USA., Willems SM; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge, UK., Sivapalaratnam S; Massachusetts General Hospital, Boston, MA, USA.; Department of Vascular Medicine, AMC, Amsterdam, The Netherlands.; Department of Haematology, University of Cambridge, Cambridge, UK., Abecasis G; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA.; School of Public Health, University of Michigan, Ann Arbor, MI, USA., Alam DS; School of Kinesiology and Health Science, Faculty of Health, York University, Toronto, Canada., Allison M; Department of Family Medicine & Public Health, University of California, San Diego, La Jolla, CA, USA., Amouyel P; INSERM U1167, Lille, France.; Institut Pasteur de Lille, U1167, Lille, France.; U1167-RID-AGE, Universite de Lille - Risk factors and molecular determinants of aging-related diseases, Lille, France., Arzumanyan Z; Institute for Translational Genomics and Population Sciences, LABioMed at Harbor-UCLA Medical Center, Torrance, CA, USA., Balkau B; INSERM U1018, Centre de recherche en Épidemiologie et Sante des Populations (CESP), Villejuif, France., Bastarache L; Department of Biomedical Informatics, Vanderbilt University, Nashville, TN, USA., Bergmann S; Department of Computational Biology, University of Lausanne, Lausanne, Switzerland.; Swiss Institute of Bioinformatics, Lausanne, Switzerland., Bielak LF; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, USA., Blüher M; IFB Adiposity Diseases, University of Leipzig, Leipzig, Germany.; Department of Medicine, University of Leipzig, Leipzig, Germany., Boehnke M; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA., Boeing H; Department of Epidemiology, German Institute of Human Nutrition Potsdam-Rehbruecke (DIfE), Nuthetal, Germany., Boerwinkle E; Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX, USA.; Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX, USA., Böger CA; Department of Nephrology, University Hospital Regensburg, Regensburg, Germany., Bork-Jensen J; The Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Bottinger EP; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Bowden DW; Center for Diabetes Research, Wake Forest School of Medicine, Winston-Salem, NC, USA.; Center for Genomics and Personalized Medicine Research, Wake Forest School of Medicine, Winston-Salem, NC, USA.; Department of Biochemistry, Wake Forest School of Medicine, Winston-Salem, NC, USA., Brandslund I; Department of Clinical Biochemistry, Lillebaelt Hospital, Vejle, Denmark.; Institute of Regional Health Research, University of Southern Denmark, Odense, Denmark., Broer L; Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands., Burt AA; Department of Medicine (Medical Genetics), University of Washington, Seattle, WA, USA., Butterworth AS; MRC/BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; NIHR Blood and Transplant Research Unit in Donor Health and Genomics, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Caulfield MJ; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.; NIHR Barts Cardiovascular Research Centre, Barts and The London School of Medicine & Dentistry, Queen Mary University of London, London, UK., Cesana G; Research Centre on Public Health, University of Milano-Bicocca, Monza, Italy., Chambers JC; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore.; Department of Cardiology, London North West Healthcare NHS Trust, Ealing Hospital, Middlesex, UK.; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK.; Imperial College Healthcare NHS Trust, London, UK.; MRC-PHE Centre for Environment and Health, Imperial College London, London, UK., Chasman DI; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Division of Genetics, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.; Division of Preventive Medicine, Brigham and Women's and Harvard Medical School, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA., Chen YI; Institute for Translational Genomics and Population Sciences, LABioMed at Harbor-UCLA Medical Center, Torrance, CA, USA., Chowdhury R; MRC/BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Christensen C; Medical department, Lillebaelt Hospital, Vejle, Denmark., Chu AY; Division of Preventive Medicine, Brigham and Women's and Harvard Medical School, Boston, MA, USA., Collins FS; Medical Genomics and Metabolic Genetics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA., Cook JP; Department of Biostatistics, University of Liverpool, Liverpool, UK., Cox AJ; Center for Diabetes Research, Wake Forest School of Medicine, Winston-Salem, NC, USA.; Center for Genomics and Personalized Medicine Research, Wake Forest School of Medicine, Winston-Salem, NC, USA.; Menzies Health Institute Queensland, Griffith University, Southport, Queensland, Australia., Crosslin DS; Department of Biomedical Infomatics and Medical Education, University of Washington, Seattle, WA, USA., Danesh J; MRC/BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; NIHR Blood and Transplant Research Unit in Donor Health and Genomics, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; Wellcome Trust Sanger Institute, Hinxton, UK.; British Heart Foundation Cambridge Centre of Excellence, Department of Medicine, University of Cambridge, Cambridge, UK., de Bakker PIW; Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands.; Department of Genetics, Center for Molecular Medicine, University Medical Center Utrecht, Utrecht, The Netherlands., Denus S; Montreal Heart Institute, Universite de Montreal, Montreal, Quebec, Canada.; Faculty of Pharmacy, Universite de Montreal, Montreal, Quebec, Canada., Mutsert R; Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands., Dedoussis G; Department of Nutrition and Dietetics, School of Health Science and Education, Harokopio University, Athens, Greece., Demerath EW; Division of Epidemiology & Community Health, School of Public Health, University of Minnesota, Minneapolis, MN, USA., Dennis JG; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Denny JC; Department of Biomedical Informatics, Vanderbilt University, Nashville, TN, USA., Di Angelantonio E; MRC/BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; NIHR Blood and Transplant Research Unit in Donor Health and Genomics, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; British Heart Foundation Cambridge Centre of Excellence, Department of Medicine, University of Cambridge, Cambridge, UK., Dörr M; Department of Internal Medicine B, University Medicine Greifswald, Greifswald, Germany.; DZHK (German Centre for Cardiovascular Research), partner site Greifswald, Greifswald, Germany., Drenos F; Institute of Cardiovascular Science, University College London, London, UK.; MRC Integrative Epidemiology Unit, School of Social and Community Medicine, University of Bristol, Bristol, UK.; Department of Life Sciences, Brunel University London, Uxbridge, UK., Dubé MP; Montreal Heart Institute, Universite de Montreal, Montreal, Quebec, Canada.; Department of Medicine, Faculty of Medicine, Universite de Montreal, Montreal, Quebec, Canada., Dunning AM; Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK., Easton DF; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK., Elliott P; Department of Epidemiology and Biostatistics, MRC-PHE Centre for Environment and Health, School of Public Health, Imperial College London, London, UK., Evangelou E; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK.; Department of Hygiene and Epidemiology, University of Ioannina Medical School, Ioannina, Greece., Farmaki AE; Department of Nutrition and Dietetics, School of Health Science and Education, Harokopio University, Athens, Greece., Feng S; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA., Ferrannini E; CNR Institute of Clinical Physiology, Pisa, Italy.; Department of Clinical & Experimental Medicine, University of Pisa, Pisa, Italy., Ferrieres J; Toulouse University School of Medicine, Toulouse, France., Florez JC; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Medicine, Harvard University Medical School, Boston, MA, USA.; Massachusetts General Hospital, Boston, MA, USA., Fornage M; Institute of Molecular Medicine, The University of Texas Health Science Center at Houston, Houston, TX, USA., Fox CS; NHLBI Framingham Heart Study, Framingham, MA, USA., Franks PW; Department of Clinical Sciences, Genetic and Molecular Epidemiology Unit, Lund University, Malmo, Sweden.; Department of Nutrition, Harvard School of Public Health, Boston, MA, USA.; Department of Public Health and Clinical Medicine, Unit of Medicine, Umeå University, Umeå, Sweden., Friedrich N; Institute of Clinical Chemistry and Laboratory Medicine, University Medicine Greifswald, Greifswald, Germany., Gan W; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK., Gandin I; Ilaria Gandin, Research Unit, AREA Science Park, Trieste, Italy., Gasparini P; Department of Medical Sciences, University of Trieste, Trieste, Italy.; Institute for Maternal and Child Health-IRCCS Burlo Garofolo, Trieste, Italy., Giedraitis V; Geriatrics, Department of Public Health, Uppsala University, Uppsala, Sweden., Girotto G; Department of Medical Sciences, University of Trieste, Trieste, Italy.; Institute for Maternal and Child Health-IRCCS Burlo Garofolo, Trieste, Italy., Gorski M; Department of Genetic Epidemiology, University of Regensburg, Regensburg, Germany.; Department of Nephrology, University Hospital Regensburg, Regensburg, Germany., Grallert H; German Center for Diabetes Research, München-Neuherberg, Germany.; Institute of Epidemiology II, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany., Grarup N; The Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Grove ML; Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX, USA., Gustafsson S; Department of Medical Sciences, Molecular Epidemiology and Science for Life Laboratory, Uppsala University, Uppsala, Sweden., Haessler J; Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle WA, USA., Hansen T; The Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Hattersley AT; University of Exeter Medical School, University of Exeter, Exeter, UK., Hayward C; MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK., Heid IM; Department of Genetic Epidemiology, University of Regensburg, Regensburg, Germany.; Institute of Genetic Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany., Holmen OL; K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health, NTNU, Norwegian University of Science and Technology, Trondheim, Norway., Hovingh GK; Department of Vascular Medicine, AMC, Amsterdam, The Netherlands., Howson JMM; MRC/BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Hu Y; CAS Key Laboratory of Nutrition, Metabolism and Food Safety, Shanghai Institute of Nutrition and Health, Shanghai Institutes for Biological Sciences, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, China., Hung YJ; Division of Endocrinology and Metabolism, Department of Internal Medicine, Tri-Service General Hospital Songshan Branch, Taipei, Taiwan.; School of Medicine, National Defense Medical Center, Taipei, Taiwan., Hveem K; K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health, NTNU, Norwegian University of Science and Technology, Trondheim, Norway.; HUNT Research Center, Department of Public Health, Norwegian University of Science and Technology, Levanger, Norway., Ikram MA; Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands.; Department of Neurology, Erasmus Medical Center, Rotterdam, The Netherlands.; Department of Radiology, Erasmus Medical Center, Rotterdam, The Netherlands., Ingelsson E; Department of Medical Sciences, Molecular Epidemiology and Science for Life Laboratory, Uppsala University, Uppsala, Sweden.; Stanford Cardiovascular Institute, Stanford University, Stanford, CA, USA., Jackson AU; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA., Jarvik GP; Department of Medicine (Medical Genetics), University of Washington, Seattle, WA, USA.; Department of Genome Sciences, University of Washington, Seattle, WA, USA., Jia Y; Institute for Translational Genomics and Population Sciences, LABioMed at Harbor-UCLA Medical Center, Torrance, CA, USA., Jørgensen T; Faculty of Medicine, Aalborg University, Aalborg, Denmark.; Department of Public Health, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; Research Center for Prevention and Health, Capital Region of Denmark, Glostrup, Denmark., Jousilahti P; National Institute for Health and Welfare, Helsinki, Finland., Justesen JM; The Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Kahali B; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, USA.; Department of Internal Medicine, University of Michigan, Ann Arbor, MI, USA.; Division of Gastroenterology, University of Michigan, Ann Arbor, MI, USA.; Centre for Brain Research, Indian Institute of Science, Bangalore, India., Karaleftheri M; Echinos Medical Centre, Echinos, Greece., Kardia SLR; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, USA., Karpe F; Oxford Centre for Diabetes, Endocrinology and Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.; Oxford NIHR Biomedical Research Centre, Oxford University Hospitals Trust, Oxford, UK., Kee F; UKCRC Centre of Excellence for Public Health Research, Queens University Belfast, Belfast, UK., Kitajima H; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK., Komulainen P; Foundation for Research in Health Exercise and Nutrition, Kuopio Research Institute of Exercise Medicine, Kuopio, Finland., Kooner JS; Department of Cardiology, London North West Healthcare NHS Trust, Ealing Hospital, Middlesex, UK.; Imperial College Healthcare NHS Trust, London, UK.; MRC-PHE Centre for Environment and Health, Imperial College London, London, UK.; National Heart and Lung Institute, Imperial College London, Hammersmith Hospital Campus, London, UK., Kovacs P; IFB Adiposity Diseases, University of Leipzig, Leipzig, Germany., Krämer BK; University Medical Centre Mannheim, 5th Medical Department, University of Heidelberg, Mannheim, Germany., Kuulasmaa K; National Institute for Health and Welfare, Helsinki, Finland., Kuusisto J; Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio, Finland., Laakso M; Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio, Finland., Lakka TA; Foundation for Research in Health Exercise and Nutrition, Kuopio Research Institute of Exercise Medicine, Kuopio, Finland.; Institute of Biomedicine, School of Medicine, University of Eastern Finland, Kuopio Campus, Finland.; Department of Clinical Physiology and Nuclear Medicine, Kuopio University Hospital, Kuopio, Finland., Lamparter D; Department of Computational Biology, University of Lausanne, Lausanne, Switzerland.; Swiss Institute of Bioinformatics, Lausanne, Switzerland.; Verge Genomics, San Fransico, CA, USA., Lange LA; Division of Biomedical and Personalized Medicine, Department of Medicine, University of Colorado-Denver, Aurora, CO, USA., Langenberg C; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge, UK., Larson EB; Department of Medicine (Medical Genetics), University of Washington, Seattle, WA, USA.; Kaiser Permanente Washington Health Research Institute, Seattle, WA, USA.; Department of Health Services, University of Washington, Seattle, WA, USA., Lee NR; Department of Anthropology, Sociology, and History, University of San Carlos, Cebu City, Philippines.; USC-Office of Population Studies Foundation, Inc., University of San Carlos, Cebu City, Philippines., Lee WJ; Department of Medical Research, Taichung Veterans General Hospital, Taichung, Taiwan.; Department of Social Work, Tunghai University, Taichung, Taiwan., Lehtimäki T; Department of Clinical Chemistry, Fimlab Laboratories, Tampere, Finland.; Department of Clinical Chemistry, Finnish Cardiovascular Research Center-Tampere, Faculty of Medicine and Life Sciences, University of Tampere, Tampere, Finland., Lewis CE; Division of Preventive Medicine, University of Alabama at Birmingham, Birmingham, AL, USA., Li H; CAS Key Laboratory of Nutrition, Metabolism and Food Safety, Shanghai Institute of Nutrition and Health, Shanghai Institutes for Biological Sciences, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, China., Li J; Department of Medicine, Division of Cardiovascular Medicine, Stanford University School of Medicine, Palo Alto, CA, USA., Li-Gao R; Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands., Lin LA; Institute of Molecular Medicine, The University of Texas Health Science Center at Houston, Houston, TX, USA., Lin X; CAS Key Laboratory of Nutrition, Metabolism and Food Safety, Shanghai Institute of Nutrition and Health, Shanghai Institutes for Biological Sciences, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, China., Lind L; Uppsala University, Uppsala, Sweden., Lindström J; National Institute for Health and Welfare, Helsinki, Finland., Linneberg A; Research Center for Prevention and Health, Capital Region of Denmark, Glostrup, Denmark.; Center for Clinical Research and Prevention, Bispebjerg and Frederiksberg Hospital, Frederiksberg, Denmark.; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Liu CT; Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA., Liu DJ; Department of Public Health Sciences, Institute for Personalized Medicine, The Pennsylvania State University College of Medicine, Hershey, PA, USA., Luan J; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge, UK., Lyytikäinen LP; Department of Clinical Chemistry, Fimlab Laboratories, Tampere, Finland.; Department of Clinical Chemistry, Finnish Cardiovascular Research Center-Tampere, Faculty of Medicine and Life Sciences, University of Tampere, Tampere, Finland., MacGregor S; QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia., Mägi R; Estonian Genome Center, University of Tartu, Tartu, Estonia., Männistö S; National Institute for Health and Welfare, Helsinki, Finland., Marenne G; Wellcome Trust Sanger Institute, Hinxton, UK., Marten J; MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK., Masca NGD; Department of Cardiovascular Sciences, Univeristy of Leicester, Glenfield Hospital, Leicester, UK.; NIHR Leicester Cardiovascular Biomedical Research Unit, Glenfield Hospital, Leicester, UK., McCarthy MI; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.; Oxford Centre for Diabetes, Endocrinology and Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.; Oxford NIHR Biomedical Research Centre, Oxford University Hospitals Trust, Oxford, UK., Meidtner K; German Center for Diabetes Research, München-Neuherberg, Germany.; Department of Molecular Epidemiology, German Institute of Human Nutrition Potsdam-Rehbruecke (DIfE), Nuthetal, Germany., Mihailov E; Estonian Genome Center, University of Tartu, Tartu, Estonia., Moilanen L; Department of Medicine, Kuopio University Hospital, Kuopio, Finland., Moitry M; Department of Epidemiology and Public Health, University of Strasbourg, Strasbourg, France.; Department of Public Health, University Hospital of Strasbourg, Strasbourg, France., Mook-Kanamori DO; Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands.; Department of Public Health and Primary Care, Leiden University Medical Center, Leiden, The Netherlands., Morgan A; Department of Medical Sciences, University of Trieste, Trieste, Italy., Morris AP; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.; Department of Biostatistics, University of Liverpool, Liverpool, UK., Müller-Nurasyid M; Institute of Genetic Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.; Department of Medicine I, University Hospital Grosshadern, Ludwig-Maximilians-Universitat, Munich, Germany.; DZHK (German Centre for Cardiovascular Research), partner site Munich Heart Alliance, Munich, Germany., Munroe PB; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.; NIHR Barts Cardiovascular Research Centre, Barts and The London School of Medicine & Dentistry, Queen Mary University of London, London, UK., Narisu N; Medical Genomics and Metabolic Genetics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA., Nelson CP; Department of Cardiovascular Sciences, Univeristy of Leicester, Glenfield Hospital, Leicester, UK.; NIHR Leicester Cardiovascular Biomedical Research Unit, Glenfield Hospital, Leicester, UK., Neville M; Oxford Centre for Diabetes, Endocrinology and Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.; Oxford NIHR Biomedical Research Centre, Oxford University Hospitals Trust, Oxford, UK., Ntalla I; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK., O'Connell JR; Program for Personalized and Genomic Medicine, Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, USA., Owen KR; Oxford Centre for Diabetes, Endocrinology and Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.; Oxford NIHR Biomedical Research Centre, Oxford University Hospitals Trust, Oxford, UK., Pedersen O; The Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Peloso GM; Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA., Pennell CE; Division of Obstetric and Gynaecology, School of Medicine, The University of Western Australia, Perth, Western Australia, Australia.; School of Medicine and Public Health, Faculty of Medicine and Health, The University of Newcastle, Newcastle, New South Wales, Australia., Perola M; National Institute for Health and Welfare, Helsinki, Finland.; Institute for Molecular Medicine (FIMM) and Diabetes and Obesity Research Program, University of Helsinki, Helsinki, Finland., Perry JA; Program for Personalized and Genomic Medicine, Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, USA., Perry JRB; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge, UK., Pers TH; The Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark., Ewing A; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Polasek O; School of Medicine, University of Split, Split, Croatia.; Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK., Raitakari OT; Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Turku, Finland.; Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, Finland., Rasheed A; Centre for Non-Communicable Diseases, Karachi, Pakistan., Raulerson CK; Department of Genetics, University of North Carolina, Chapel Hill, NC, USA., Rauramaa R; Foundation for Research in Health Exercise and Nutrition, Kuopio Research Institute of Exercise Medicine, Kuopio, Finland.; Institute of Biomedicine, School of Medicine, University of Eastern Finland, Kuopio Campus, Finland., Reilly DF; Genetics and Pharmacogenomics, Merck & Co., Inc., Boston, MA, USA., Reiner AP; Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle WA, USA.; Department of Epidemiology, University of Washington, Seattle, WA, USA., Ridker PM; Division of Preventive Medicine, Brigham and Women's and Harvard Medical School, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA.; Division of Cardiovascular Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA., Rivas MA; Department of Biomedical Data Science, Stanford University, Stanford, CA, USA., Robertson NR; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.; Oxford Centre for Diabetes, Endocrinology and Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, UK., Robino A; Institute for Maternal and Child Health, IRCCS 'Burlo Garofolo', Trieste, Italy., Rudan I; Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK., Ruth KS; Genetics of Complex Traits, University of Exeter Medical School, University of Exeter, Exeter, UK., Saleheen D; Centre for Non-Communicable Diseases, Karachi, Pakistan.; Department of Biostatistics and Epidemiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Salomaa V; National Institute for Health and Welfare, Helsinki, Finland., Samani NJ; Department of Cardiovascular Sciences, Univeristy of Leicester, Glenfield Hospital, Leicester, UK.; NIHR Leicester Cardiovascular Biomedical Research Unit, Glenfield Hospital, Leicester, UK., Schreiner PJ; Division of Epidemiology & Community Health, University of Minnesota, Minneapolis, MN, USA., Schulze MB; German Center for Diabetes Research, München-Neuherberg, Germany.; Department of Molecular Epidemiology, German Institute of Human Nutrition Potsdam-Rehbruecke (DIfE), Nuthetal, Germany., Scott RA; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge, UK., Segura-Lepe M; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK., Sim X; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA.; Saw Swee Hock School of Public Health, National University Health System, National University of Singapore, Singapore, Singapore., Slater AJ; Genetics, Target Sciences, GlaxoSmithKline, Research Triangle Park, NC, USA.; OmicSoft a QIAGEN Company, Cary, NC, USA., Small KS; Department of Twin Research and Genetic Epidemiology, King's College London, London, UK., Smith BH; Division of Population Health Sciences, Ninewells Hospital and Medical School, University of Dundee, Dundee, UK.; Generation Scotland, Centre for Genomic and Experimental Medicine, University of Edinburgh, Edinburgh, UK., Smith JA; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, USA., Southam L; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.; Wellcome Trust Sanger Institute, Hinxton, UK., Spector TD; Department of Twin Research and Genetic Epidemiology, King's College London, London, UK., Speliotes EK; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, USA.; Department of Internal Medicine, University of Michigan, Ann Arbor, MI, USA.; Division of Gastroenterology, University of Michigan, Ann Arbor, MI, USA., Stefansson K; deCODE Genetics/Amgen Inc., Reykjavik, Iceland.; Faculty of Medicine, University of Iceland, Reykjavik, Iceland., Steinthorsdottir V; deCODE Genetics/Amgen Inc., Reykjavik, Iceland., Stirrups KE; 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Radboud Institute for Health Sciences, Radboud University Medical Center, Nijmegen, The Netherlands., Vestergaard H; The Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; Steno Diabetes Center Copenhagen, Gentofte, Denmark., Vitart V; MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK., Vogt TF; Cardiometabolic Disease, Merck & Co., Inc., Kenilworth, NJ, USA., Vuckovic D; Department of Medical Sciences, University of Trieste, Trieste, Italy.; Institute for Maternal and Child Health-IRCCS Burlo Garofolo, Trieste, Italy., Wagenknecht LE; Division of Public Health Sciences, Wake Forest School of Medicine, Winston-Salem, NC, USA., Walker M; Institute of Cellular Medicine, The Medical School, Newcastle University, Newcastle, UK., Wallentin L; Department of Medical Sciences, Cardiology, Uppsala Clinical Research Center, Uppsala University, Uppsala, Sweden., Wang F; 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Department of Biostatistics and Epidemiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Zheng H; CAS Key Laboratory of Nutrition, Metabolism and Food Safety, Shanghai Institute of Nutrition and Health, Shanghai Institutes for Biological Sciences, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, China., Zhou W; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, USA.; Department of Internal Medicine, University of Michigan, Ann Arbor, MI, USA., Zillikens MC; Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands.; Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands., Rivadeneira F; Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands.; Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands., Borecki IB; Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St. Louis, MO, USA., Pospisilik JA; Max Planck Institute of Immunobiology and Epigenetics, Freiburg, Germany., Deloukas P; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.; Princess Al-Jawhara Al-Brahim Centre of Excellence in Research of Hereditary Disorders (PACER-HD), King Abdulaziz University, Jeddah, Saudi Arabia., Frayling TM; Genetics of Complex Traits, University of Exeter Medical School, University of Exeter, Exeter, UK., Lettre G; Montreal Heart Institute, Universite de Montreal, Montreal, Quebec, Canada.; Department of Medicine, Faculty of Medicine, Universite de Montreal, Montreal, Quebec, Canada., Mohlke KL; Department of Genetics, University of North Carolina, Chapel Hill, NC, USA., Rotter JI; Institute for Translational Genomics and Population Sciences, LABioMed at Harbor-UCLA Medical Center, Torrance, CA, USA., Kutalik Z; Swiss Institute of Bioinformatics, Lausanne, Switzerland.; Institute of Social and Preventive Medicine, Lausanne University Hospital, Lausanne, Switzerland., Hirschhorn JN; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Division of Endocrinology and Center for Basic and Translational Obesity Research, Boston Children's Hospital, Boston, MA, USA.; Departments of Pediatrics and Genetics, Harvard Medical School, Boston, MA, USA., Cupples LA; NHLBI Framingham Heart Study, Framingham, MA, USA.; Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA., Loos RJF; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; The Genetics of Obesity and Related Metabolic Traits Program, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; The Mindich Child Health and Development Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA., North KE; Department of Epidemiology and Carolina Center of Genome Sciences, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA. kari_north@unc.edu., Lindgren CM; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK. celi@well.ox.ac.uk.; Li Ka Shing Centre for Health Information and Discovery, The Big Data Institute, University of Oxford, Oxford, UK. celi@well.ox.ac.uk.
Publikováno v:
Nature genetics [Nat Genet] 2019 Mar; Vol. 51 (3), pp. 452-469. Date of Electronic Publication: 2019 Feb 18.
Autor:
Liu DJ; Department of Public Health Sciences, Institute of Personalized Medicine, Penn State College of Medicine, Hershey, Pennsylvania, USA., Peloso GM; Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, USA.; Program in Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts, USA., Yu H; Department of Stem Cell and Regenerative Biology, Harvard Stem Cell Institute, Harvard University, Cambridge, Massachusetts, USA., Butterworth AS; MRC/BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; The National Institute for Health Research Blood and Transplant Research Unit (NIHR BTRU) in Donor Health and Genomics at the University of Cambridge, Cambridge, UK., Wang X; Cardiovascular Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA., Mahajan A; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK., Saleheen D; MRC/BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; Department of Biostatistics and Epidemiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.; Center for Non-Communicable Diseases, Karachi, Pakistan., Emdin C; Program in Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts, USA.; Center for Genomic Medicine, Massachusetts General Hospital, Boston, Massachusetts, USA., Alam D; ICDDR, B, Dhaka, Bangladesh., Alves AC; Imperial College London, London, UK., Amouyel P; Université Lille, INSERM, CHU Lille, Institut Pasteur de Lille, U1167-RID-AGE-Risk Factors and Molecular Determinants of Aging-related Diseases, Lille, France., Di Angelantonio E; MRC/BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; The National Institute for Health Research Blood and Transplant Research Unit (NIHR BTRU) in Donor Health and Genomics at the University of Cambridge, Cambridge, UK., Arveiler D; Department of Epidemiology and Public Health, EA 3430, University of Strasbourg, Strasbourg, France., Assimes TL; VA Palo Alto Health Care System, Palo Alto, California, USA.; Department of Medicine, Stanford University School of Medicine, Stanford, California, USA., Auer PL; Zilber School of Public Health, University of Wisconsin-Milwaukee, Milwaukee, Wisconsin, USA., Baber U; Cardiovascular Institute, Mount Sinai Medical Center, Icahn School of Medicine at Mount Sinai, New York, New York, USA., Ballantyne CM; Department of Medicine, Baylor College of Medicine, Houston, Texas, USA., Bang LE; Department of Cardiology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark., Benn M; Department of Clinical Biochemistry, Rigshospitalet, Copenhagen, Denmark.; Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Bis JC; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, Washington, USA., Boehnke M; Center for Statistical Genetics, Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, Michigan, USA., Boerwinkle E; Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, Texas, USA.; Human Genome Sequencing Center, Baylor College of Medicine, Houston, Texas, USA., Bork-Jensen J; The Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Bottinger EP; The Charles Bronfman Institute for Personalized Medicine, Ichan School of Medicine at Mount Sinai, New York, New York, USA., Brandslund I; Department of Clinical Biochemistry, Lillebaelt Hospital, Vejle, Denmark.; Institute of Regional Health Research, University of Southern Denmark, Odense, Denmark., Brown M; Clinical Pharmacology, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK., Busonero F; Istituto di Ricerca Genetica e Biomedica, Consiglio Nazionale delle Ricerche (CNR), Monserrato, Cagliari, Italy., Caulfield MJ; Clinical Pharmacology, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.; The Barts Heart Centre, William Harvey Research Institute, Queen Mary University of London, London, UK.; NIHR Barts Cardiovascular Biomedical Research Unit, Queen Mary University of London, London, UK., Chambers JC; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK.; Department of Cardiology, Ealing Hospital NHS Trust, Southall, UK.; Imperial College Healthcare NHS Trust, London, UK., Chasman DI; Division of Preventive Medicine, Brigham and Women's Hospital, Boston, Massachusetts, USA.; Department of Medicine, Harvard Medical School, Boston, Massachusetts, USA., Chen YE; Department of Internal Medicine, Division of Cardiovascular Medicine, University of Michigan, Ann Arbor, Michigan, USA., Chen YI; The Institute for Translational Genomics and Population Sciences, LABioMed at Harbor-UCLA Medical Center, Departments of Pediatrics and Medicine, Los Angeles, California, USA., Chowdhury R; MRC/BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Christensen C; Medical Department, Lillebaelt Hospital, Vejle, Denmark., Chu AY; Division of Preventive Medicine, Brigham and Women's Hospital, Boston, Massachusetts, USA.; NHLBI Framingham Heart Study, Framingham, Massachusetts, USA., Connell JM; Medical Research Institute, Ninewells Hospital and Medical School, University of Dundee, Dundee, UK., Cucca F; Istituto di Ricerca Genetica e Biomedica, Consiglio Nazionale delle Ricerche (CNR), Monserrato, Cagliari, Italy.; Dipartimento di Scienze Biomediche, Università degli Studi di Sassari, Sassari, Italy., Cupples LA; Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, USA.; NHLBI Framingham Heart Study, Framingham, Massachusetts, USA., Damrauer SM; Corporal Michael Crescenz VA Medical Center, Philadelphia, Pennsylvania, USA.; Department of Surgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA., Davies G; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK.; Department of Psychology, University of Edinburgh, Edinburgh, UK., Deary IJ; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK.; Department of Psychology, University of Edinburgh, Edinburgh, UK., Dedoussis G; Department of Nutrition and Dietetics, School of Health Science and Education, Harokopio University, Athens, Greece., Denny JC; Department of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, Tennessee, USA.; Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA., Dominiczak A; British Heart Foundation Glasgow Cardiovascular Research Centre, Institute of Cardiovascular and Medical Sciences, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, UK., Dubé MP; Montreal Heart Institute, Montreal, Quebec, Canada.; Université de Montréal Beaulieu-Saucier Pharmacogenomics Center, Montreal, Quebec, Canada.; Université de Montréal, Montreal, Quebec, Canada., Ebeling T; Department of Medicine, Oulu University Hospital and University of Oulu, Oulu, Finland., Eiriksdottir G; The Icelandic Heart Association, Kopavogur, Iceland., Esko T; Program in Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts, USA.; Estonian Genome Center, University of Tartu, Tartu, Estonia., Farmaki AE; Department of Nutrition and Dietetics, School of Health Science and Education, Harokopio University, Athens, Greece., Feitosa MF; Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St. Louis, Missouri, USA., Ferrario M; Research Centre in Epidemiology and Preventive Medicine-EPIMED, Department of Medicine and Surgery, University of Insubria, Varese, Italy., Ferrieres J; Department of Epidemiology, UMR 1027-INSERM, Toulouse University-CHU Toulouse, Toulouse, France., Ford I; Robertson Centre for Biostatistics, University of Glasgow, Glasgow, UK., Fornage M; Institute of Molecular Medicine, The University of Texas Health Science Center at Houston, Houston, Texas, USA., Franks PW; Department of Clinical Sciences, Genetic and Molecular Epidemiology Unit, Lund University, Malmö, Sweden.; Department of Public Health & Clinical Medicine, Umeå University, Umeå, Sweden.; Department of Nutrition, Harvard T. H. Chan School of Public Health, Boston, Massachusetts, USA., Frayling TM; Genetics of Complex Traits, University of Exeter Medical School, University of Exeter, Exeter, UK., Frikke-Schmidt R; Department of Clinical Biochemistry, Rigshospitalet, Copenhagen, Denmark.; Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Fritsche LG; Center for Statistical Genetics, Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, Michigan, USA., Frossard P; Center for Non-Communicable Diseases, Karachi, Pakistan., Fuster V; Cardiovascular Institute, Mount Sinai Medical Center, Icahn School of Medicine at Mount Sinai, New York, New York, USA.; Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC), Madrid, Spain., Ganesh SK; Department of Internal Medicine, Division of Cardiovascular Medicine, University of Michigan, Ann Arbor, Michigan, USA.; Department of Human Genetics, University of Michigan, Ann Arbor, Michigan, USA., Gao W; Department of Cardiology, Peking University Third Hospital, Key Laboratory of Cardiovascular Molecular Biology and Regulatory Peptides, Ministry of Health, Beijing, China., Garcia ME; National Heart, Lung, and Blood Institute, Bethesda, Maryland, USA., Gieger C; German Center for Diabetes Research (DZD e.V.), Neuherberg, Germany.; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; Institute of Epidemiology II, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany., Giulianini F; Division of Preventive Medicine, Brigham and Women's Hospital, Boston, Massachusetts, USA., Goodarzi MO; Departments of Medicine and of Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, California, USA.; Division of Endocrinology, Diabetes and Metabolism, Cedars-Sinai Medical Center, Los Angeles, California, USA., Grallert H; German Center for Diabetes Research (DZD e.V.), Neuherberg, Germany.; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; Institute of Epidemiology II, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany., Grarup N; The Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Groop L; Department of Clinical Sciences, Diabetes and Endocrinology, Clinical Research Centre, Lund University, Malmö, Sweden., Grove ML; Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, Texas, USA., Gudnason V; The Icelandic Heart Association, Kopavogur, Iceland.; Faculty of Medicine, University of Iceland, Reykjavik, Iceland., Hansen T; The Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; Faculty of Health Sciences, University of Southern Denmark, Odense, Denmark., Harris TB; Laboratory of Epidemiology and Population Sciences, National Institute on Aging, Bethesda, Maryland, USA., Hayward C; Medical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK., Hirschhorn JN; Program in Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts, USA.; Division of Endocrinology and Center for Basic and Translational Obesity Research, Boston Children's Hospital, Boston, Massachusetts, USA., Holmen OL; Department of Public Health and General Practice, HUNT Research Centre, Norwegian University of Science and Technology, Levanger, Norway.; St. Olavs Hospital, Trondheim University Hospital, Trondheim, Norway., Huffman J; Medical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK., Huo Y; Department of Cardiology, Peking University First Hospital, Beijing, China., Hveem K; K. G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology (NTNU), Trondheim, Norway., Jabeen S; Center for Non-Communicable Diseases, Karachi, Pakistan., Jackson AU; Center for Statistical Genetics, Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, Michigan, USA., Jakobsdottir J; The Icelandic Heart Association, Kopavogur, Iceland.; Department of Health Sciences, University of Iceland, Reykjavik, Iceland., Jarvelin MR; Imperial College London, London, UK., Jensen GB; The Copenhagen City Heart Study, Frederiksberg Hospital, Copenhagen, Denmark., Jørgensen ME; Steno Diabetes Center, Gentofte, Denmark.; National Institute of Public Health, Southern Denmark University, Copenhagen, Denmark., Jukema JW; Department of Cardiology, Leiden University Medical Center, Leiden, the Netherlands.; The Interuniversity Cardiology Institute of the Netherlands, Utrecht, the Netherlands., Justesen JM; The Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Kamstrup PR; Department of Clinical Biochemistry and the Copenhagen General Population Study, Herlev and Gentofte Hospital, Copenhagen University Hospital, Copenhagen, Denmark., Kanoni S; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK., Karpe F; Oxford Centre for Diabetes, Endocrinology and Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.; Oxford NIHR Biomedical Research Centre, Oxford University Hospitals Trust, Oxford, UK., Kee F; UKCRC Centre of Excellence for Public Health, Queens University, Belfast, UK., Khera AV; Program in Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts, USA.; Center for Genomic Medicine, Massachusetts General Hospital, Boston, Massachusetts, USA., Klarin D; Program in Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts, USA.; Center for Genomic Medicine, Massachusetts General Hospital, Boston, Massachusetts, USA.; Massachusetts Veterans Epidemiology Research and Information Center (MAVERIC), VA Boston Healthcare System, Boston, Massachusetts, USA., Koistinen HA; Department of Health, National Institute for Health and Welfare, Helsinki, Finland.; Department of Medicine and Abdominal Center: Endocrinology, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland.; Minerva Foundation Institute for Medical Research, Helsinki, Finland., Kooner JS; Department of Cardiology, Ealing Hospital NHS Trust, Southall, UK.; Imperial College Healthcare NHS Trust, London, UK.; National Heart and Lung Institute, Imperial College London, Hammersmith Hospital, London, UK., Kooperberg C; Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA., Kuulasmaa K; Department of Health, National Institute for Health and Welfare, Helsinki, Finland., Kuusisto J; Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio, Finland., Laakso M; Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio, Finland., Lakka T; Department of Physiology, Institute of Biomedicine, University of Eastern Finland, Kuopio Campus, Kuopio, Finland.; Kuopio Research Institute of Exercise Medicine, Kuopio, Finland.; Department of Clinical Physiology and Nuclear Medicine, Kuopio University Hospital, Kuopio, Finland., Langenberg C; MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge School of Clinical Medicine, Cambridge, UK., Langsted A; Department of Clinical Biochemistry and the Copenhagen General Population Study, Herlev and Gentofte Hospital, Copenhagen University Hospital, Copenhagen, Denmark.; Faculty of Health and Medical Sciences, University of Denmark, Copenhagen, Denmark., Launer LJ; Laboratory of Epidemiology and Population Sciences, National Institute on Aging, Bethesda, Maryland, USA., Lauritzen T; Department of Public Health, Section of General Practice, University of Aarhus, Aarhus, Denmark., Liewald DCM; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK.; Department of Psychology, University of Edinburgh, Edinburgh, UK., Lin LA; Institute of Molecular Medicine, The University of Texas Health Science Center at Houston, Houston, Texas, USA., Linneberg A; Department of Clinical Experimental Research, Rigshospitalet, Glostrup, Denmark.; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; Research Center for Prevention and Health, Copenhagen, Denmark., Loos RJF; The Charles Bronfman Institute for Personalized Medicine, Ichan School of Medicine at Mount Sinai, New York, New York, USA.; The Mindich Child Health and Development Institute, Ichan School of Medicine at Mount Sinai, New York, New York, USA., Lu Y; The Charles Bronfman Institute for Personalized Medicine, Ichan School of Medicine at Mount Sinai, New York, New York, USA., Lu X; Department of Internal Medicine, Division of Cardiovascular Medicine, University of Michigan, Ann Arbor, Michigan, USA.; State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China., Mägi R; Estonian Genome Center, University of Tartu, Tartu, Estonia., Malarstig A; Cardiovascular Genetics and Genomics Group, Cardiovascular Medicine Unit, Department of Medicine, Solna, Karolinska Institutet, Stockholm, Sweden.; Pharmatherapeutics Clinical Research, Pfizer Worldwide R&D, Sollentuna, Sweden., Manichaikul A; Center for Public Health Genomics, University of Virginia, Charlottesville, Virginia, USA., Manning AK; Program in Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts, USA.; Center for Genomic Medicine, Massachusetts General Hospital, Boston, Massachusetts, USA.; Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts, USA., Mäntyselkä P; Unit of Primary Health Care, University of Eastern Finland and Kuopio University Hospital, Kuopio, Finland., Marouli E; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK., Masca NGD; Department of Cardiovascular Sciences, University of Leicester, Leicester, UK.; NIHR Leicester Biomedical Research Centre, Glenfield Hospital, Leicester, UK., Maschio A; Istituto di Ricerca Genetica e Biomedica, Consiglio Nazionale delle Ricerche (CNR), Monserrato, Cagliari, Italy., Meigs JB; Program in Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts, USA.; Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts, USA.; Division of General Internal Medicine, Massachusetts General Hospital, Boston, Massachusetts, USA., Melander O; Department of Clinical Sciences, University Hospital Malmo Clinical Research Center, Lund University, Malmo, Sweden., Metspalu A; Estonian Genome Center, University of Tartu, Tartu, Estonia., Morris AP; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.; Department of Biostatistics, University of Liverpool, Liverpool, UK., Morrison AC; Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, Texas, USA., Mulas A; Istituto di Ricerca Genetica e Biomedica, Consiglio Nazionale delle Ricerche (CNR), Monserrato, Cagliari, Italy., Müller-Nurasyid M; Institute of Epidemiology II, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.; Department of Medicine I, Ludwig-Maximilians-University, Munich, Germany.; DZHK German Centre for Cardiovascular Research, Munich Heart Alliance, Munich, Germany., Munroe PB; Clinical Pharmacology, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.; NIHR Barts Cardiovascular Biomedical Research Unit, Queen Mary University of London, London, UK., Neville MJ; Oxford Centre for Diabetes, Endocrinology and Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, UK., Nielsen JB; Department of Internal Medicine, Division of Cardiovascular Medicine, University of Michigan, Ann Arbor, Michigan, USA., Nielsen SF; Department of Clinical Biochemistry and the Copenhagen General Population Study, Herlev and Gentofte Hospital, Copenhagen University Hospital, Copenhagen, Denmark.; Faculty of Health and Medical Sciences, University of Denmark, Copenhagen, Denmark., Nordestgaard BG; Department of Clinical Biochemistry and the Copenhagen General Population Study, Herlev and Gentofte Hospital, Copenhagen University Hospital, Copenhagen, Denmark.; Faculty of Health and Medical Sciences, University of Denmark, Copenhagen, Denmark., Ordovas JM; Department of Cardiovascular Epidemiology and Population Genetics, National Center for Cardiovascular Investigation, Madrid, Spain.; IMDEA-Alimentacion, Madrid, Spain.; Nutrition and Genomics Laboratory, Jean Mayer-USDA Human Nutrition Research Center on Aging at Tufts University, Boston, Massachusetts, USA., Mehran R; Cardiovascular Institute, Mount Sinai Medical Center, Icahn School of Medicine at Mount Sinai, New York, New York, USA., O'Donnell CJ; 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Center for Genomic Medicine, Massachusetts General Hospital, Boston, Massachusetts, USA.; Department of Medicine, Harvard Medical School, Boston, Massachusetts, USA.; Cardiovascular Research Center, Massachusetts General Hospital, Boston, Massachusetts, USA., Pedersen O; The Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Perola M; Department of Health, National Institute for Health and Welfare, Helsinki, Finland.; Institute of Molecular Medicine FIMM, University of Helsinki, Finland., Peters A; German Center for Diabetes Research (DZD e.V.), Neuherberg, Germany.; Institute of Epidemiology II, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.; DZHK German Centre for Cardiovascular Research, Munich Heart Alliance, Munich, Germany., Pisinger C; Research Center for Prevention and Health, Copenhagen, Denmark., Pistis G; Istituto di Ricerca Genetica e Biomedica, Consiglio Nazionale delle Ricerche (CNR), Monserrato, Cagliari, Italy., Polasek O; Faculty of Medicine, University of Split, Split, Croatia.; Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK., Poulter N; International Centre for Circulatory Health, Imperial College London, London, UK., Psaty BM; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, Washington, USA.; Kaiser Permanente Washington Health Research Institute, Seattle, Washington, USA.; Departments of Epidemiology and Health Services, University of Washington, Seattle, Washington, USA., Rader DJ; Departments of Genetics, Medicine, and Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA., Rasheed A; Center for Non-Communicable Diseases, Karachi, Pakistan., Rauramaa R; Kuopio Research Institute of Exercise Medicine, Kuopio, Finland.; Department of Clinical Physiology and Nuclear Medicine, Kuopio University Hospital, Kuopio, Finland., Reilly DF; Genetics, Merck Sharp & Dohme Corporation, Kenilworth, New Jersey, USA., Reiner AP; Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA.; Department of Epidemiology, University of Washington, Seattle, Washington, USA., Renström F; Department of Clinical Sciences, Genetic and Molecular Epidemiology Unit, Lund University, Malmö, Sweden.; Department of Biobank Research, Umeå University, Umeå, Sweden., Rich SS; Center for Public Health Genomics, University of Virginia, Charlottesville, Virginia, USA., Ridker PM; Division of Preventive Medicine, Brigham and Women's Hospital, Boston, Massachusetts, USA., Rioux JD; Montreal Heart Institute, Montreal, Quebec, Canada., Robertson NR; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.; Oxford Centre for Diabetes, Endocrinology and Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, UK., Roden DM; Department of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, Tennessee, USA.; Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA., Rotter JI; 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William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.; Department of Haematology, University of Cambridge, Cambridge, UK., Stitziel N; Cardiovascular Division, Departments of Medicine and Genetics, Washington University School of Medicine, St. Louis, Missouri, USA.; The McDonnell Genome Institute, Washington University School of Medicine, St. Louis, Missouri, USA., Strauch K; IBE, Faculty of Medicine, Ludwig-Maximilians-Universität Munich, Germany.; Institute of Genetic Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany., Stringham HM; Center for Statistical Genetics, Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, Michigan, USA., Surendran P; MRC/BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Tada H; Division of Cardiovascular Medicine, Kanazawa University Graduate School of Medicine, Kanazawa, Japan., Tall AR; Department of Medicine, Division of Molecular Medicine, Columbia University, New York, New York, USA., Tang H; Department of Genetics, Stanford University School of Medicine, Stanford, California, USA., Tardif JC; Montreal Heart Institute, Montreal, Quebec, Canada.; Université de Montréal, Montreal, Quebec, Canada., Taylor KD; The Institute for Translational Genomics and Population Sciences, LABioMed at Harbor-UCLA Medical Center, Departments of Pediatrics and Medicine, Los Angeles, California, USA., Trompet S; Department of Cardiology, Leiden University Medical Center, Leiden, the Netherlands.; Department of Gerontology and Geriatrics, Leiden University Medical Center, Leiden, the Netherlands., Tsao PS; VA Palo Alto Health Care System, Palo Alto, California, USA.; Department of Medicine, Stanford University School of Medicine, Stanford, California, USA., Tuomilehto J; Chronic Disease Prevention Unit, National Institute for Health and Welfare, Helsinki, Finland.; Dasman Diabetes Institute, Dasman, Kuwait.; Centre for Vascular Prevention, Danube-University Krems, Krems, Austria.; Saudi Diabetes Research Group, King Abdulaziz University, Fahd Medical Research Center, Jeddah, Saudi Arabia., Tybjaerg-Hansen A; Department of Clinical Biochemistry, Rigshospitalet, Copenhagen, Denmark.; Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., van Zuydam NR; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.; Medical Research Institute, Ninewells Hospital and Medical School, University of Dundee, Dundee, UK., Varbo A; Department of Clinical Biochemistry and the Copenhagen General Population Study, Herlev and Gentofte Hospital, Copenhagen University Hospital, Copenhagen, Denmark.; Faculty of Health and Medical Sciences, University of Denmark, Copenhagen, Denmark., Varga TV; Department of Clinical Sciences, Genetic and Molecular Epidemiology Unit, Lund University, Malmö, Sweden., Virtamo J; Department of Health, National Institute for Health and Welfare, Helsinki, Finland., Waldenberger M; 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Center for Statistical Genetics, Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, Michigan, USA., Wessel J; Department of Epidemiology, Indiana University Fairbanks School of Public Health, Indianapolis, Indiana, USA.; Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana, USA., Wilson JG; Department of Physiology and Biophysics, University of Mississippi Medical Center, Jackson, Mississippi, USA., Wilson PWF; Atlanta VA Medical Center, Decatur, Georgia, USA.; Emory Clinical Cardiovascular Research Institute, Atlanta, Georgia, USA., Xu M; Department of Cardiology, Institute of Vascular Medicine, Peking University Third Hospital, Key Laboratory of Molecular Cardiovascular Sciences, Ministry of Education, Beijing, China., Yaghootkar H; Genetics of Complex Traits, University of Exeter Medical School, University of Exeter, Exeter, UK., Young R; MRC/BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Zeggini E; 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Publikováno v:
Nature genetics [Nat Genet] 2017 Dec; Vol. 49 (12), pp. 1758-1766. Date of Electronic Publication: 2017 Oct 30.
Autor:
Holmen OL; 1] HUNT Research Centre, Department of Public Health and General Practice, Norwegian University of Science and Technology, Levanger, Norway. [2] St. Olavs Hospital, Trondheim University Hospital, Trondheim, Norway. [3]., Zhang H; 1] Department of Internal Medicine, Division of Cardiovascular Medicine, University of Michigan, Ann Arbor, Michigan, USA. [2]., Fan Y; 1] Department of Internal Medicine, Division of Cardiovascular Medicine, University of Michigan, Ann Arbor, Michigan, USA. [2]., Hovelson DH; 1] Department of Internal Medicine, Division of Cardiovascular Medicine, University of Michigan, Ann Arbor, Michigan, USA. [2] Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, Michigan, USA., Schmidt EM; 1] Department of Internal Medicine, Division of Cardiovascular Medicine, University of Michigan, Ann Arbor, Michigan, USA. [2] Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, Michigan, USA., Zhou W; Department of Internal Medicine, Division of Cardiovascular Medicine, University of Michigan, Ann Arbor, Michigan, USA., Guo Y; Department of Internal Medicine, Division of Cardiovascular Medicine, University of Michigan, Ann Arbor, Michigan, USA., Zhang J; Department of Internal Medicine, Division of Cardiovascular Medicine, University of Michigan, Ann Arbor, Michigan, USA., Langhammer A; HUNT Research Centre, Department of Public Health and General Practice, Norwegian University of Science and Technology, Levanger, Norway., Løchen ML; Epidemiology of Chronic Diseases Research Group, Department of Community Medicine, Faculty of Health Sciences, UiT The Arctic University of Norway, Tromsø, Norway., Ganesh SK; 1] Department of Internal Medicine, Division of Cardiovascular Medicine, University of Michigan, Ann Arbor, Michigan, USA. [2] Department of Human Genetics, University of Michigan, Ann Arbor, Michigan, USA., Vatten L; Department of Public Health, Norwegian University of Science and Technology, Trondheim, Norway., Skorpen F; Department of Laboratory Medicine, Children's and Women's Health, Norwegian University of Science and Technology, Trondheim, Norway., Dalen H; 1] Department of Medicine, Levanger Hospital, Nord-Trøndelag Health Trust, Levanger, Norway. [2] Medical Imaging Laboratory for Innovative Future Healthcare, Department of Circulation and Medical Imaging, Norwegian University of Science and Technology, Trondheim, Norway., Zhang J; Department of Internal Medicine, Division of Cardiovascular Medicine, University of Michigan, Ann Arbor, Michigan, USA., Pennathur S; Department of Internal Medicine, Division of Nephrology, University of Michigan, Ann Arbor, Michigan, USA., Chen J; Department of Internal Medicine, Division of Cardiovascular Medicine, University of Michigan, Ann Arbor, Michigan, USA., Platou C; Department of Medicine, Levanger Hospital, Nord-Trøndelag Health Trust, Levanger, Norway., Mathiesen EB; 1] Brain and Circulation Research Group, Department of Clinical Medicine, Faculty of Health Sciences, UiT The Arctic University of Norway, Tromsø, Norway. [2] Brain and Circulation Research Group, University Hospital of North Norway, Tromsø, Norway., Wilsgaard T; Epidemiology of Chronic Diseases Research Group, Department of Community Medicine, Faculty of Health Sciences, UiT The Arctic University of Norway, Tromsø, Norway., Njølstad I; Epidemiology of Chronic Diseases Research Group, Department of Community Medicine, Faculty of Health Sciences, UiT The Arctic University of Norway, Tromsø, Norway., Boehnke M; Department of Biostatistics, Center for Statistical Genetics, University of Michigan School of Public Health, Ann Arbor, Michigan, USA., Chen YE; Department of Internal Medicine, Division of Cardiovascular Medicine, University of Michigan, Ann Arbor, Michigan, USA., Abecasis GR; Department of Biostatistics, Center for Statistical Genetics, University of Michigan School of Public Health, Ann Arbor, Michigan, USA., Hveem K; 1] HUNT Research Centre, Department of Public Health and General Practice, Norwegian University of Science and Technology, Levanger, Norway. [2] Department of Medicine, Levanger Hospital, Nord-Trøndelag Health Trust, Levanger, Norway., Willer CJ; 1] Department of Internal Medicine, Division of Cardiovascular Medicine, University of Michigan, Ann Arbor, Michigan, USA. [2] Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, Michigan, USA. [3] Department of Human Genetics, University of Michigan, Ann Arbor, Michigan, USA.
Publikováno v:
Nature genetics [Nat Genet] 2014 Apr; Vol. 46 (4), pp. 345-51. Date of Electronic Publication: 2014 Mar 16.
Autor:
Liu DJ; 1] Center for Statistical Genetics, Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, Michigan, USA. [2]., Peloso GM; 1] Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA. [2] Center for Human Genetic Research, Massachusetts General Hospital, Boston, Massachusetts, USA. [3] Cardiovascular Research Center, Massachusetts General Hospital, Boston, Massachusetts, USA. [4]., Zhan X; 1] Center for Statistical Genetics, Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, Michigan, USA. [2]., Holmen OL; 1] HUNT Research Centre, Department of Public Health and General Practice, Norwegian University of Science and Technology, Levanger, Norway. [2] St. Olav Hospital, Trondheim University Hospital, Trondheim, Norway. [3]., Zawistowski M; Center for Statistical Genetics, Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, Michigan, USA., Feng S; Center for Statistical Genetics, Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, Michigan, USA., Nikpay M; University of Ottawa Heart Institute, Ottawa, Ontario, Canada., Auer PL; 1] Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA. [2] School of Public Health, University of Wisconsin-Milwaukee, Milwaukee, Wisconsin, USA., Goel A; 1] Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK. [2] Department of Cardiovascular Medicine, University of Oxford, Oxford, UK., Zhang H; 1] Division of Cardiology, Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, Michigan, USA. [2] Department of Human Genetics, University of Michigan Medical School, Ann Arbor, Michigan, USA., Peters U; 1] Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA. [2] Department of Epidemiology, University of Washington School of Public Health, Seattle, Washington, USA., Farrall M; 1] Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK. [2] Department of Cardiovascular Medicine, University of Oxford, Oxford, UK., Orho-Melander M; 1] Department of Cardiovascular Medicine, University of Oxford, Oxford, UK. [2] Department of Clinical Sciences, Lund University, Malmö, Sweden., Kooperberg C; 1] Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA. [2] Department of Biostatistics, University of Washington School of Public Health, Seattle, Washington, USA., McPherson R; University of Ottawa Heart Institute, Ottawa, Ontario, Canada., Watkins H; 1] Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK. [2] Department of Cardiovascular Medicine, University of Oxford, Oxford, UK., Willer CJ; 1] Division of Cardiology, Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, Michigan, USA. [2] Department of Human Genetics, University of Michigan Medical School, Ann Arbor, Michigan, USA., Hveem K; 1] HUNT Research Centre, Department of Public Health and General Practice, Norwegian University of Science and Technology, Levanger, Norway. [2] Department of Medicine, Levanger Hospital, Nord-Trøndelag Health Trust, Levanger, Norway., Melander O; 1] Department of Cardiovascular Medicine, University of Oxford, Oxford, UK. [2] Department of Clinical Sciences, Lund University, Malmö, Sweden., Kathiresan S; 1] Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA. [2] Center for Human Genetic Research, Massachusetts General Hospital, Boston, Massachusetts, USA. [3] Cardiovascular Research Center, Massachusetts General Hospital, Boston, Massachusetts, USA. [4] Department of Medicine, Harvard Medical School, Boston, Massachusetts, USA. [5]., Abecasis GR; 1] Center for Statistical Genetics, Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, Michigan, USA. [2].
Publikováno v:
Nature genetics [Nat Genet] 2014 Feb; Vol. 46 (2), pp. 200-4. Date of Electronic Publication: 2013 Dec 15.
Loss-of-function genomic variants highlight potential therapeutic targets for cardiovascular disease
Autor:
Nielsen, Jonas B, Rom, Oren, Surakka, Ida, Graham, Sarah E, Zhou, Wei, Roychowdhury, Tanmoy, Fritsche, Lars G, Gagliano Taliun, Sarah A, Sidore, Carlo, Liu, Yuhao, Gabrielsen, Maiken E, Skogholt, Anne Heidi, Wolford, Brooke, Overton, William, Zhao, Ying, Chen, Jin, Zhang, He, Hornsby, Whitney E, Acheampong, Akua, Grooms, Austen, Schaefer, Amanda, Zajac, Gregory JM, Villacorta, Luis, Zhang, Jifeng, Brumpton, Ben, Løset, Mari, Rai, Vivek, Lundegaard, Pia R, Olesen, Morten S, Taylor, Kent D, Palmer, Nicholette D, Chen, Yii-Der, Choi, Seung H, Lubitz, Steven A, Ellinor, Patrick T, Barnes, Kathleen C, Daya, Michelle, Rafaels, Nicholas, Weiss, Scott T, Lasky-Su, Jessica, Tracy, Russell P, Vasan, Ramachandran S, Cupples, L Adrienne, Mathias, Rasika A, Yanek, Lisa R, Becker, Lewis C, Peyser, Patricia A, Bielak, Lawrence F, Smith, Jennifer A, Aslibekyan, Stella, Hidalgo, Bertha A, Arnett, Donna K, Irvin, Marguerite R, Wilson, James G, Musani, Solomon K, Correa, Adolfo, Rich, Stephen S, Guo, Xiuqing, Rotter, Jerome I, Konkle, Barbara A, Johnsen, Jill M, Ashley-Koch, Allison E, Telen, Marilyn J, Sheehan, Vivien A, Blangero, John, Curran, Joanne E, Peralta, Juan M, Montgomery, Courtney, Sheu, Wayne H-H, Chung, Ren-Hua, Schwander, Karen, Nouraie, Seyed M, Gordeuk, Victor R, Zhang, Yingze, Kooperberg, Charles, Reiner, Alexander P, Jackson, Rebecca D, Bleecker, Eugene R, Meyers, Deborah A, Li, Xingnan, Das, Sayantan, Yu, Ketian, LeFaive, Jonathon, Smith, Albert, Blackwell, Tom, Taliun, Daniel, Zollner, Sebastian, Forer, Lukas, Schoenherr, Sebastian, Fuchsberger, Christian, Pandit, Anita, Zawistowski, Matthew, Kheterpal, Sachin, Brummett, Chad M, Natarajan, Pradeep, Schlessinger, David, Lee, Seunggeun, Kang, Hyun Min, Cucca, Francesco, Holmen, Oddgeir L
Publikováno v:
Nature communications, vol 11, iss 1
Pharmaceutical drugs targeting dyslipidemia and cardiovascular disease (CVD) may increase the risk of fatty liver disease and other metabolic disorders. To identify potential novel CVD drug targets without these adverse effects, we perform genome-wid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::5d0f980fbe0d617bd1e47bd91d18febe
https://escholarship.org/uc/item/4fx41254
https://escholarship.org/uc/item/4fx41254
Autor:
Justice, Anne E, Karaderi, Tugce, Highland, Heather M, Young, Kristin L, Graff, Mariaelisa, Lu, Yingchang, Turcot, Valérie, Auer, Paul L, Fine, Rebecca S, Guo, Xiuqing, Schurmann, Claudia, Lempradl, Adelheid, Marouli, Eirini, Mahajan, Anubha, Winkler, Thomas W, Locke, Adam E, Medina-Gomez, Carolina, Esko, Tõnu, Vedantam, Sailaja, Giri, Ayush, Lo, Ken Sin, Alfred, Tamuno, Mudgal, Poorva, Ng, Maggie CY, Heard-Costa, Nancy L, Feitosa, Mary F, Manning, Alisa K, Willems, Sara M, Sivapalaratnam, Suthesh, Abecasis, Goncalo, Alam, Dewan S, Allison, Matthew, Amouyel, Philippe, Arzumanyan, Zorayr, Balkau, Beverley, Bastarache, Lisa, Bergmann, Sven, Bielak, Lawrence F, Blüher, Matthias, Boehnke, Michael, Boeing, Heiner, Boerwinkle, Eric, Böger, Carsten A, Bork-Jensen, Jette, Bottinger, Erwin P, Bowden, Donald W, Brandslund, Ivan, Broer, Linda, Burt, Amber A, Butterworth, Adam S, Caulfield, Mark J, Cesana, Giancarlo, Chambers, John C, Chasman, Daniel I, Chen, Yii-Der Ida, Chowdhury, Rajiv, Christensen, Cramer, Chu, Audrey Y, Collins, Francis S, Cook, James P, Cox, Amanda J, Crosslin, David S, Danesh, John, de Bakker, Paul IW, Denus, Simon de, Mutsert, Renée de, Dedoussis, George, Demerath, Ellen W, Dennis, Joe G, Denny, Josh C, Angelantonio, Emanuele Di, Dörr, Marcus, Drenos, Fotios, Dubé, Marie-Pierre, Dunning, Alison M, Easton, Douglas F, Elliott, Paul, Evangelou, Evangelos, Farmaki, Aliki-Eleni, Feng, Shuang, Ferrannini, Ele, Ferrieres, Jean, Florez, Jose C, Fornage, Myriam, Fox, Caroline S, Franks, Paul W, Friedrich, Nele, Gan, Wei, Gandin, Ilaria, Gasparini, Paolo, Giedraitis, Vilmantas, Girotto, Giorgia, Gorski, Mathias, Grallert, Harald, Grarup, Niels, Grove, Megan L, Gustafsson, Stefan, Haessler, Jeff, Hansen, Torben, Hattersley, Andrew T, Hayward, Caroline, Heid, Iris M, Holmen, Oddgeir L, Hovingh, G Kees, Howson, Joanna MM, Hu, Yao, Hung, Yi-Jen, Hveem, Kristian, Ikram, M Arfan, Ingelsson, Erik, Jackson, Anne U, Jarvik, Gail P, Jia, Yucheng, Jørgensen, Torben, Jousilahti, Pekka, Justesen, Johanne M, Kahali, Bratati, Karaleftheri, Maria, Kardia, Sharon LR, Karpe, Fredrik, Kee, Frank, Kitajima, Hidetoshi, Komulainen, Pirjo, Kooner, Jaspal S, Kovacs, Peter, Krämer, Bernhard K, Kuulasmaa, Kari, Kuusisto, Johanna, Laakso, Markku, Lakka, Timo A, Lamparter, David, Lange, Leslie A, Langenberg, Claudia, Larson, Eric B, Lee, Nanette R, Lee, Wen-Jane, Lehtimäki, Terho, Lewis, Cora E, Li, Huaixing, Li, Jin, Li-Gao, Ruifang, Lin, Li-An, Lin, Xu, Lind, Lars, Lindström, Jaana, Linneberg, Allan, Liu, Ching-Ti, Liu, Dajiang J, Luan, Jian'an, Lyytikäinen, Leo-Pekka, MacGregor, Stuart, Mägi, Reedik, Männistö, Satu, Marenne, Gaëlle, Marten, Jonathan, Masca, Nicholas GD, McCarthy, Mark I, Meidtner, Karina, Mihailov, Evelin, Moilanen, Leena, Moitry, Marie, Mook-Kanamori, Dennis O, Morgan, Anna, Morris, Andrew P, Müller-Nurasyid, Martina, Munroe, Patricia B, Narisu, Narisu, Nelson, Christopher P, Neville, Matt, Ntalla, Ioanna, O'Connell, Jeffrey R, Owen, Katharine R, Pedersen, Oluf, Peloso, Gina M, Pennell, Craig E, Perola, Markus, Perry, James A, Perry, John RB, Pers, Tune H, Ewing, Ailith, Polasek, Ozren, Raitakari, Olli T, Rasheed, Asif, Raulerson, Chelsea K, Rauramaa, Rainer, Reilly, Dermot F, Reiner, Alex P, Ridker, Paul M, Rivas, Manuel A, Robertson, Neil R, Robino, Antonietta, Rudan, Igor, Ruth, Katherine S, Saleheen, Danish, Salomaa, Veikko, Samani, Nilesh J, Schreiner, Pamela J, Schulze, Matthias B, Scott, Robert A, Segura-Lepe, Marcelo, Sim, Xueling, Slater, Andrew J, Small, Kerrin S, Smith, Blair H, Smith, Jennifer A, Southam, Lorraine, Spector, Timothy D, Speliotes, Elizabeth K, Stefansson, Kari, Steinthorsdottir, Valgerdur, Stirrups, Kathleen E, Strauch, Konstantin, Stringham, Heather M, Stumvoll, Michael, Sun, Liang, Surendran, Praveen, Swart, Karin MA, Tardif, Jean-Claude, Taylor, Kent D, Teumer, Alexander, Thompson, Deborah J, Thorleifsson, Gudmar, Thorsteinsdottir, Unnur, Thuesen, Betina H, Tönjes, Anke, Torres, Mina, Tsafantakis, Emmanouil, Tuomilehto, Jaakko, Uitterlinden, André G, Uusitupa, Matti, van Duijn, Cornelia M, Vanhala, Mauno, Varma, Rohit, Vermeulen, Sita H, Vestergaard, Henrik, Vitart, Veronique, Vogt, Thomas F, Vuckovic, Dragana, Wagenknecht, Lynne E, Walker, Mark, Wallentin, Lars, Wang, Feijie, Wang, Carol A, Wang, Shuai, Wareham, Nicholas J, Warren, Helen R, Waterworth, Dawn M, Wessel, Jennifer, White, Harvey D, Willer, Cristen J, Wilson, James G, Wood, Andrew R, Wu, Ying, Yaghootkar, Hanieh, Yao, Jie, Yerges-Armstrong, Laura M, Young, Robin, Zeggini, Eleftheria, Zhan, Xiaowei, Zhang, Weihua, Zhao, Jing Hua, Zhao, Wei, Zheng, He, Zhou, Wei, Zillikens, M Carola, CHD Exome+ Consortium, Cohorts for Heart and Aging Research in Genomic Epidemiology (CH, EPIC-CVD Consortium, ExomeBP Consortium, Global Lipids Genetic Consortium, GoT2D Genes Consortium, InterAct, ReproGen Consortium, T2D-Genes Consortium, MAGIC Investigators, Rivadeneira, Fernando, Borecki, Ingrid B, Pospisilik, J Andrew, Deloukas, Panos, Frayling, Timothy M, Lettre, Guillaume, Mohlke, Karen L, Rotter, Jerome I, Kutalik, Zoltán, Hirschhorn, Joel N, Cupples, L Adrienne, Loos, Ruth JF, North, Kari E, Lindgren, Cecilia M
Publikováno v:
Nature Genetics, 51, 3, pp. 452-469
Nature Genetics, 51, 452-469
Nature genetics, 51(3), 452-469. Nature Publishing Group
Nature Genetics
Nature genetics
Nature Genetics, 51(3), 452-469. Nature Publishing Group
Nature genetics, vol. 51, no. 3, pp. 452-469
Nat. Genet. 51, 452–469 (2019)
Justice, A E, Karaderi, T, Highland, H M, Young, K L, Graff, M, Lu, Y, Turcot, V, Auer, P L, Fine, R S, Guo, X, Schurmann, C, Lempradl, A, Marouli, E, Mahajan, A, Winkler, T W, Locke, A E, Medina-Gomez, C, Esko, T N, Vedantam, S, Giri, A, Lo, K S, Alfred, T, Mudgal, P, Ng, M C Y, Heard-Costa, N L, Feitosa, M F, Manning, A K, Willems, S M, Sivapalaratnam, S, Abecasis, G, Alam, D S, Allison, M, Amouyel, P, Arzumanyan, Z, Balkau, B, Bastarache, L, Bergmann, S, Bielak, L F, Blüher, M, Boehnke, M, Boeing, H, Boerwinkle, E, Böger, C A, Bork-Jensen, J, Bottinger, E P, Bowden, D W, Brandslund, I, Li, J, Swart, K M A, Vermeulen, S H, CHD Exome+ Consortium, Frayling, T M, Lettre, G, Mohlke, K L, Rotter, J I, Kutalik, Z, Hirschhorn, J N, Cupples, L A, Loos, R J F, North, K E & Lindgren, C M 2019, ' Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution ', Nature Genetics, vol. 51, pp. 452–469 . https://doi.org/10.1038/s41588-018-0334-2
Justice, A E, Karaderi, T, Highland, H M, Young, K L, Graff, M, Lu, Y, Turcot, V, Auer, P L, Fine, R S, Guo, X, Schurmann, C, Lempradl, A, Marouli, E, Mahajan, A, Winkler, T W, Locke, A E, Medina-Gomez, C, Esko, T, Vedantam, S, Giri, A, Lo, K S, Alfred, T, Mudgal, P, Ng, M C Y, Heard-Costa, N L, Feitosa, M F, Manning, A K, Willems, S M, Sivapalaratnam, S, Abecasis, G, Alam, D S, Allison, M, Amouyel, P, Arzumanyan, Z, Balkau, B, Bastarache, L, Bergmann, S, Bielak, L F, Blüher, M, Boehnke, M, Boeing, H, Boerwinkle, E, Böger, C A, Bork-Jensen, J, Bottinger, E P, Bowden, D W, Brandslund, I, Broer, L, Burt, A A, Butterworth, A S, Caulfield, M J, Cesana, G, Chambers, J C, Chasman, D I, Chen, Y-D I, Chowdhury, R, Christensen, C, Chu, A Y, Collins, F S, Cook, J P, Cox, A J, Crosslin, D S, Danesh, J, de Bakker, P I W, de Denus, S, de Mutsert, R, Dedoussis, G, Demerath, E W, Dennis, J G, Denny, J C, Di Angelantonio, E, Dörr, M, Drenos, F, Dubé, M-P, Dunning, A M, Easton, D F, Elliott, P, Evangelou, E, Farmaki, A-E, Feng, S, Ferrannini, E, Ferrieres, J, Florez, J C, Fornage, M, Fox, C S, Franks, P W, Friedrich, N, Gan, W, Gandin, I, Gasparini, P, Giedraitis, V, Girotto, G, Gorski, M, Grallert, H, Grarup, N, Grove, M L, Gustafsson, S, Haessler, J, Hansen, T, Hattersley, A T, Hayward, C, Heid, I M, Holmen, O L, Kees Hovingh, G, Howson, J M M, Hu, Y, Hung, Y-J, Hveem, K, Ikram, M A, Ingelsson, E, Jackson, A U, Jarvik, G P, Jia, Y, Jørgensen, T, Jousilahti, P, Justesen, J M, Kahali, B, Karaleftheri, M, Kardia, S L R, Karpe, F, Kee, F, Kitajima, H, Komulainen, P, Kooner, J S, Kovacs, P, Krämer, B K, Kuulasmaa, K, Kuusisto, J, Laakso, M, Lakka, T A, Lamparter, D, Lange, L A, Langenberg, C, Larson, E B, Lee, N R, Lee, W-J, Lehtimäki, T, Lewis, C E, Li, H, Li, J, Li-Gao, R, Lin, L-A, Lin, X, Lind, L, Lindström, J, Linneberg, A, Liu, C-T, Liu, D J, Luan, J, Lyytikäinen, L-P, MacGregor, S, Mägi, R, Männistö, S, Marenne, G, Marten, J, Masca, N G D, McCarthy, M I, Meidtner, K, Mihailov, E, Moilanen, L, Moitry, M, Mook-Kanamori, D O, Morgan, A, Morris, A P, Müller-Nurasyid, M, Munroe, P B, Narisu, N, Nelson, C P, Neville, M, Ntalla, I, Owen, K R, O'Connell, J R, Pedersen, O, Peloso, G M, Pennell, C E, Perola, M, Perry, J A, Perry, J R B, Pers, T H, Ewing, A, Polasek, O, Raitakari, O T, Rasheed, A, Raulerson, C K, Rauramaa, R, Reilly, D F, Reiner, A P, Ridker, P M, Rivas, M A, Robertson, N R, Robino, A, Rudan, I, Ruth, K S, Saleheen, D, Salomaa, V, Samani, N J, Schreiner, P J, Schulze, M B, Scott, R A, Segura-Lepe, M, Sim, X, Slater, A J, Small, K S, Smith, B H, Smith, J A, Southam, L, Spector, T D, Speliotes, E K, Stefansson, K, Steinthorsdottir, V, Stirrups, K E, Strauch, K, Stringham, H M, Stumvoll, M, Sun, L, Surendran, P, Swart, K M A, Tardif, J-C, Taylor, K D, Teumer, A, Thompson, D J, Thorleifsson, G, Thorsteinsdottir, U, Thuesen, B H, Tönjes, A, Torres, M, Tsafantakis, E, Tuomilehto, J, Uitterlinden, A G, Uusitupa, M, van Duijn, C M, Vanhala, M, Varma, R, Vermeulen, S H, Vestergaard, H, Vitart, V, Vogt, T F, Vuckovic, D, Wagenknecht, L E, Walker, M, Wallentin, L, Wang, F, Wang, C A, Wang, S, Wareham, N J, Warren, H R, Waterworth, D M, Wessel, J, White, H D, Willer, C J, Wilson, J G, Wood, A R, Wu, Y, Yaghootkar, H, Yao, J, Yerges-Armstrong, L M, Young, R, Zeggini, E, Zhan, X, Zhang, W, Hua Zhao, J, Zhao, W, Zheng, H, Zhou, W, Zillikens, M C, CHD Exome+ Consortium, Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium, EPIC-CVD consortium, ExomeBP Consortium, Global Lipids Genetic Consortium, GoT2D Genes Consortium, InterAct, ReproGen Consortium, T2D-Genes Consortium, The MAGIC Investigators, Rivadeneira, F, Borecki, I B, Pospisilik, J A, Deloukas, P, Frayling, T M, Lettre, G, Mohlke, K L, Rotter, J I, Kutalik, Z, Hirschhorn, J N, Cupples, L A, Loos, R J F, North, K E & Lindgren, C M 2019, ' Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution ', Nature Genetics, vol. 51, no. 3, pp. 452-469 . https://doi.org/10.1038/s41588-018-0334-2
CHD Exome+ Consortium 2019, ' Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution ', Nature Genetics, vol. 51, no. 3, pp. 452-469 . https://doi.org/10.1038/s41588-018-0334-2
Nature Genetics, 51(3), 452
T2D-Genes Consortium, The MAGIC Investigators, CHD Exome+ Consortium, Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium, EPIC-CVD Consortium, ExomeBP Consortium, Global Lipids Genetic Consortium, GoT2D Genes Consortium, InterAct & ReproGen Consortium 2019, ' Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution ', Nature Genetics, vol. 51, no. 3, pp. 452-469 . https://doi.org/10.1038/s41588-018-0334-2
2019, ' Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution ', Nature Genetics . https://doi.org/10.1038/s41588-018-0334-2
CHD Exome+ Consortium 2019, ' Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body fat distribution ', Nature Genetics, vol. xx, no. xx, xx, pp. xx . https://doi.org/10.1038/s41588-018-0334-2
Nature Genetics, 51. Nature Publishing Group
Justice, A E, Karaderi, T, Highland, H M, Young, K L, Graff, M, Lu, Y, Turcot, V, Auer, P L, Fine, R S, Guo, X, Schurmann, C, Lempradl, A, Marouli, E, Mahajan, A, Winkler, T W, Locke, A E, Medina-Gomez, C, Esko, T, Vedantam, S, Giri, A, Lo, K S, Alfred, T, Mudgal, P, Ng, M C Y, Heard-Costa, N L, Feitosa, M F, Manning, A K, Willems, S M, Sivapalaratnam, S, Abecasis, G, Alam, D S, Allison, M, Amouyel, P, Arzumanyan, Z, Balkau, B, Bastarache, L, Bergmann, S, Bielak, L F, Blüher, M, Boehnke, M, Boeing, H, Boerwinkle, E, Böger, C A, Bork-Jensen, J, Bottinger, E P, Bowden, D W, Brandslund, I, Christensen, C, Hansen, T, Thuesen, B H & CHD Exome+ Consortium 2019, ' Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution ', Nature Genetics, vol. 51, no. 3, pp. 452-469 . https://doi.org/10.1038/s41588-018-0334-2
Nature Genetics, 51, 452-469
Nature genetics, 51(3), 452-469. Nature Publishing Group
Nature Genetics
Nature genetics
Nature Genetics, 51(3), 452-469. Nature Publishing Group
Nature genetics, vol. 51, no. 3, pp. 452-469
Nat. Genet. 51, 452–469 (2019)
Justice, A E, Karaderi, T, Highland, H M, Young, K L, Graff, M, Lu, Y, Turcot, V, Auer, P L, Fine, R S, Guo, X, Schurmann, C, Lempradl, A, Marouli, E, Mahajan, A, Winkler, T W, Locke, A E, Medina-Gomez, C, Esko, T N, Vedantam, S, Giri, A, Lo, K S, Alfred, T, Mudgal, P, Ng, M C Y, Heard-Costa, N L, Feitosa, M F, Manning, A K, Willems, S M, Sivapalaratnam, S, Abecasis, G, Alam, D S, Allison, M, Amouyel, P, Arzumanyan, Z, Balkau, B, Bastarache, L, Bergmann, S, Bielak, L F, Blüher, M, Boehnke, M, Boeing, H, Boerwinkle, E, Böger, C A, Bork-Jensen, J, Bottinger, E P, Bowden, D W, Brandslund, I, Li, J, Swart, K M A, Vermeulen, S H, CHD Exome+ Consortium, Frayling, T M, Lettre, G, Mohlke, K L, Rotter, J I, Kutalik, Z, Hirschhorn, J N, Cupples, L A, Loos, R J F, North, K E & Lindgren, C M 2019, ' Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution ', Nature Genetics, vol. 51, pp. 452–469 . https://doi.org/10.1038/s41588-018-0334-2
Justice, A E, Karaderi, T, Highland, H M, Young, K L, Graff, M, Lu, Y, Turcot, V, Auer, P L, Fine, R S, Guo, X, Schurmann, C, Lempradl, A, Marouli, E, Mahajan, A, Winkler, T W, Locke, A E, Medina-Gomez, C, Esko, T, Vedantam, S, Giri, A, Lo, K S, Alfred, T, Mudgal, P, Ng, M C Y, Heard-Costa, N L, Feitosa, M F, Manning, A K, Willems, S M, Sivapalaratnam, S, Abecasis, G, Alam, D S, Allison, M, Amouyel, P, Arzumanyan, Z, Balkau, B, Bastarache, L, Bergmann, S, Bielak, L F, Blüher, M, Boehnke, M, Boeing, H, Boerwinkle, E, Böger, C A, Bork-Jensen, J, Bottinger, E P, Bowden, D W, Brandslund, I, Broer, L, Burt, A A, Butterworth, A S, Caulfield, M J, Cesana, G, Chambers, J C, Chasman, D I, Chen, Y-D I, Chowdhury, R, Christensen, C, Chu, A Y, Collins, F S, Cook, J P, Cox, A J, Crosslin, D S, Danesh, J, de Bakker, P I W, de Denus, S, de Mutsert, R, Dedoussis, G, Demerath, E W, Dennis, J G, Denny, J C, Di Angelantonio, E, Dörr, M, Drenos, F, Dubé, M-P, Dunning, A M, Easton, D F, Elliott, P, Evangelou, E, Farmaki, A-E, Feng, S, Ferrannini, E, Ferrieres, J, Florez, J C, Fornage, M, Fox, C S, Franks, P W, Friedrich, N, Gan, W, Gandin, I, Gasparini, P, Giedraitis, V, Girotto, G, Gorski, M, Grallert, H, Grarup, N, Grove, M L, Gustafsson, S, Haessler, J, Hansen, T, Hattersley, A T, Hayward, C, Heid, I M, Holmen, O L, Kees Hovingh, G, Howson, J M M, Hu, Y, Hung, Y-J, Hveem, K, Ikram, M A, Ingelsson, E, Jackson, A U, Jarvik, G P, Jia, Y, Jørgensen, T, Jousilahti, P, Justesen, J M, Kahali, B, Karaleftheri, M, Kardia, S L R, Karpe, F, Kee, F, Kitajima, H, Komulainen, P, Kooner, J S, Kovacs, P, Krämer, B K, Kuulasmaa, K, Kuusisto, J, Laakso, M, Lakka, T A, Lamparter, D, Lange, L A, Langenberg, C, Larson, E B, Lee, N R, Lee, W-J, Lehtimäki, T, Lewis, C E, Li, H, Li, J, Li-Gao, R, Lin, L-A, Lin, X, Lind, L, Lindström, J, Linneberg, A, Liu, C-T, Liu, D J, Luan, J, Lyytikäinen, L-P, MacGregor, S, Mägi, R, Männistö, S, Marenne, G, Marten, J, Masca, N G D, McCarthy, M I, Meidtner, K, Mihailov, E, Moilanen, L, Moitry, M, Mook-Kanamori, D O, Morgan, A, Morris, A P, Müller-Nurasyid, M, Munroe, P B, Narisu, N, Nelson, C P, Neville, M, Ntalla, I, Owen, K R, O'Connell, J R, Pedersen, O, Peloso, G M, Pennell, C E, Perola, M, Perry, J A, Perry, J R B, Pers, T H, Ewing, A, Polasek, O, Raitakari, O T, Rasheed, A, Raulerson, C K, Rauramaa, R, Reilly, D F, Reiner, A P, Ridker, P M, Rivas, M A, Robertson, N R, Robino, A, Rudan, I, Ruth, K S, Saleheen, D, Salomaa, V, Samani, N J, Schreiner, P J, Schulze, M B, Scott, R A, Segura-Lepe, M, Sim, X, Slater, A J, Small, K S, Smith, B H, Smith, J A, Southam, L, Spector, T D, Speliotes, E K, Stefansson, K, Steinthorsdottir, V, Stirrups, K E, Strauch, K, Stringham, H M, Stumvoll, M, Sun, L, Surendran, P, Swart, K M A, Tardif, J-C, Taylor, K D, Teumer, A, Thompson, D J, Thorleifsson, G, Thorsteinsdottir, U, Thuesen, B H, Tönjes, A, Torres, M, Tsafantakis, E, Tuomilehto, J, Uitterlinden, A G, Uusitupa, M, van Duijn, C M, Vanhala, M, Varma, R, Vermeulen, S H, Vestergaard, H, Vitart, V, Vogt, T F, Vuckovic, D, Wagenknecht, L E, Walker, M, Wallentin, L, Wang, F, Wang, C A, Wang, S, Wareham, N J, Warren, H R, Waterworth, D M, Wessel, J, White, H D, Willer, C J, Wilson, J G, Wood, A R, Wu, Y, Yaghootkar, H, Yao, J, Yerges-Armstrong, L M, Young, R, Zeggini, E, Zhan, X, Zhang, W, Hua Zhao, J, Zhao, W, Zheng, H, Zhou, W, Zillikens, M C, CHD Exome+ Consortium, Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium, EPIC-CVD consortium, ExomeBP Consortium, Global Lipids Genetic Consortium, GoT2D Genes Consortium, InterAct, ReproGen Consortium, T2D-Genes Consortium, The MAGIC Investigators, Rivadeneira, F, Borecki, I B, Pospisilik, J A, Deloukas, P, Frayling, T M, Lettre, G, Mohlke, K L, Rotter, J I, Kutalik, Z, Hirschhorn, J N, Cupples, L A, Loos, R J F, North, K E & Lindgren, C M 2019, ' Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution ', Nature Genetics, vol. 51, no. 3, pp. 452-469 . https://doi.org/10.1038/s41588-018-0334-2
CHD Exome+ Consortium 2019, ' Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution ', Nature Genetics, vol. 51, no. 3, pp. 452-469 . https://doi.org/10.1038/s41588-018-0334-2
Nature Genetics, 51(3), 452
T2D-Genes Consortium, The MAGIC Investigators, CHD Exome+ Consortium, Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium, EPIC-CVD Consortium, ExomeBP Consortium, Global Lipids Genetic Consortium, GoT2D Genes Consortium, InterAct & ReproGen Consortium 2019, ' Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution ', Nature Genetics, vol. 51, no. 3, pp. 452-469 . https://doi.org/10.1038/s41588-018-0334-2
2019, ' Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution ', Nature Genetics . https://doi.org/10.1038/s41588-018-0334-2
CHD Exome+ Consortium 2019, ' Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body fat distribution ', Nature Genetics, vol. xx, no. xx, xx, pp. xx . https://doi.org/10.1038/s41588-018-0334-2
Nature Genetics, 51. Nature Publishing Group
Justice, A E, Karaderi, T, Highland, H M, Young, K L, Graff, M, Lu, Y, Turcot, V, Auer, P L, Fine, R S, Guo, X, Schurmann, C, Lempradl, A, Marouli, E, Mahajan, A, Winkler, T W, Locke, A E, Medina-Gomez, C, Esko, T, Vedantam, S, Giri, A, Lo, K S, Alfred, T, Mudgal, P, Ng, M C Y, Heard-Costa, N L, Feitosa, M F, Manning, A K, Willems, S M, Sivapalaratnam, S, Abecasis, G, Alam, D S, Allison, M, Amouyel, P, Arzumanyan, Z, Balkau, B, Bastarache, L, Bergmann, S, Bielak, L F, Blüher, M, Boehnke, M, Boeing, H, Boerwinkle, E, Böger, C A, Bork-Jensen, J, Bottinger, E P, Bowden, D W, Brandslund, I, Christensen, C, Hansen, T, Thuesen, B H & CHD Exome+ Consortium 2019, ' Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution ', Nature Genetics, vol. 51, no. 3, pp. 452-469 . https://doi.org/10.1038/s41588-018-0334-2
Body fat distribution is a risk factor for adverse cardiovascular health consequences. We analyzed the association of body fat distribution, assessed by waist-to-hip ratio adjusted for body mass index, with 228,985 predicted coding and splice site va
Autor:
Justice, Anne E, Karaderi, Tugce, Highland, Heather M, Young, Kristin L, Graff, Mariaelisa, Lu, Yingchang, Turcot, Valérie, Auer, Paul L, Fine, Rebecca S, Guo, Xiuqing, Schurmann, Claudia, Lempradl, Adelheid, Marouli, Eirini, Mahajan, Anubha, Winkler, Thomas W, Locke, Adam E, Medina-Gomez, Carolina, Esko, Tõnu, Vedantam, Sailaja, Giri, Ayush, Lo, Ken Sin, Alfred, Tamuno, Mudgal, Poorva, Ng, Maggie CY, Heard-Costa, Nancy L, Feitosa, Mary F, Manning, Alisa K, Willems, Sara M, Sivapalaratnam, Suthesh, Abecasis, Goncalo, Alam, Dewan S, Allison, Matthew, Amouyel, Philippe, Arzumanyan, Zorayr, Balkau, Beverley, Bastarache, Lisa, Bergmann, Sven, Bielak, Lawrence F, Blüher, Matthias, Boehnke, Michael, Boeing, Heiner, Boerwinkle, Eric, Böger, Carsten A, Bork-Jensen, Jette, Bottinger, Erwin P, Bowden, Donald W, Brandslund, Ivan, Broer, Linda, Burt, Amber A, Butterworth, Adam S, Caulfield, Mark J, Cesana, Giancarlo, Chambers, John C, Chasman, Daniel I, Chen, Yii-Der Ida, Chowdhury, Rajiv, Christensen, Cramer, Chu, Audrey Y, Collins, Francis S, Cook, James P, Cox, Amanda J, Crosslin, David S, Danesh, John, De Bakker, Paul IW, Denus, Simon De, Mutsert, Renée De, Dedoussis, George, Demerath, Ellen W, Dennis, Joe G, Denny, Josh C, Di Angelantonio, Emanuele, Dörr, Marcus, Drenos, Fotios, Dubé, Marie-Pierre, Dunning, Alison M, Easton, Douglas F, Elliott, Paul, Evangelou, Evangelos, Farmaki, Aliki-Eleni, Feng, Shuang, Ferrannini, Ele, Ferrieres, Jean, Florez, Jose C, Fornage, Myriam, Fox, Caroline S, Franks, Paul W, Friedrich, Nele, Gan, Wei, Gandin, Ilaria, Gasparini, Paolo, Giedraitis, Vilmantas, Girotto, Giorgia, Gorski, Mathias, Grallert, Harald, Grarup, Niels, Grove, Megan L, Gustafsson, Stefan, Haessler, Jeff, Hansen, Torben, Hattersley, Andrew T, Hayward, Caroline, Heid, Iris M, Holmen, Oddgeir L, Hovingh, G Kees, Howson, Joanna MM, Hu, Yao, Hung, Yi-Jen, Hveem, Kristian, Ikram, M Arfan, Ingelsson, Erik, Jackson, Anne U, Jarvik, Gail P, Jia, Yucheng, Jørgensen, Torben, Jousilahti, Pekka, Justesen, Johanne M, Kahali, Bratati, Karaleftheri, Maria, Kardia, Sharon LR, Karpe, Fredrik, Kee, Frank, Kitajima, Hidetoshi, Komulainen, Pirjo, Kooner, Jaspal S, Kovacs, Peter, Krämer, Bernhard K, Kuulasmaa, Kari, Kuusisto, Johanna, Laakso, Markku, Lakka, Timo A, Lamparter, David, Lange, Leslie A, Langenberg, Claudia, Larson, Eric B, Lee, Nanette R, Lee, Wen-Jane, Lehtimäki, Terho, Lewis, Cora E, Li, Huaixing, Li, Jin, Li-Gao, Ruifang, Lin, Li-An, Lin, Xu, Lind, Lars, Lindström, Jaana, Linneberg, Allan, Liu, Ching-Ti, Liu, Dajiang J, Luan, Jian'an, Lyytikäinen, Leo-Pekka, MacGregor, Stuart, Mägi, Reedik, Männistö, Satu, Marenne, Gaëlle, Marten, Jonathan, Masca, Nicholas GD, McCarthy, Mark I, Meidtner, Karina, Mihailov, Evelin, Moilanen, Leena, Moitry, Marie, Mook-Kanamori, Dennis O, Morgan, Anna, Morris, Andrew P, Müller-Nurasyid, Martina, Munroe, Patricia B, Narisu, Narisu, Nelson, Christopher P, Neville, Matt, Ntalla, Ioanna, O'Connell, Jeffrey R, Owen, Katharine R, Pedersen, Oluf, Peloso, Gina M, Pennell, Craig E, Perola, Markus, Perry, James A, Perry, John RB, Pers, Tune H, Ewing, Ailith, Polasek, Ozren, Raitakari, Olli T, Rasheed, Asif, Raulerson, Chelsea K, Rauramaa, Rainer, Reilly, Dermot F, Reiner, Alex P, Ridker, Paul M, Rivas, Manuel A, Robertson, Neil R, Robino, Antonietta, Rudan, Igor, Ruth, Katherine S, Saleheen, Danish, Salomaa, Veikko, Samani, Nilesh J, Schreiner, Pamela J, Schulze, Matthias B, Scott, Robert A, Segura-Lepe, Marcelo, Sim, Xueling, Slater, Andrew J, Small, Kerrin S, Smith, Blair H, Smith, Jennifer A, Southam, Lorraine, Spector, Timothy D, Speliotes, Elizabeth K, Stefansson, Kari, Steinthorsdottir, Valgerdur, Stirrups, Kathleen E, Strauch, Konstantin, Stringham, Heather M, Stumvoll, Michael, Sun, Liang, Surendran, Praveen, Swart, Karin MA, Tardif, Jean-Claude, Taylor, Kent D, Teumer, Alexander, Thompson, Deborah J, Thorleifsson, Gudmar, Thorsteinsdottir, Unnur, Thuesen, Betina H, Tönjes, Anke, Torres, Mina, Tsafantakis, Emmanouil, Tuomilehto, Jaakko, Uitterlinden, André G, Uusitupa, Matti, Van Duijn, Cornelia M, Vanhala, Mauno, Varma, Rohit, Vermeulen, Sita H, Vestergaard, Henrik, Vitart, Veronique, Vogt, Thomas F, Vuckovic, Dragana, Wagenknecht, Lynne E, Walker, Mark, Wallentin, Lars, Wang, Feijie, Wang, Carol A, Wang, Shuai, Wareham, Nicholas J, Warren, Helen R, Waterworth, Dawn M, Wessel, Jennifer, White, Harvey D, Willer, Cristen J, Wilson, James G, Wood, Andrew R, Wu, Ying, Yaghootkar, Hanieh, Yao, Jie, Yerges-Armstrong, Laura M, Young, Robin, Zeggini, Eleftheria, Zhan, Xiaowei, Zhang, Weihua, Zhao, Jing Hua, Zhao, Wei, Zheng, He, Zhou, Wei, Zillikens, M Carola, Rivadeneira, Fernando, Borecki, Ingrid B, Pospisilik, J Andrew, Deloukas, Panos, Frayling, Timothy M, Lettre, Guillaume, Mohlke, Karen L, Rotter, Jerome I, Kutalik, Zoltán, Hirschhorn, Joel N, Cupples, L Adrienne, Loos, Ruth JF, North, Kari E, Lindgren, Cecilia M, CHD Exome+ Consortium, Cohorts For Heart And Aging Research In Genomic Epidemiology (CHARGE) Consortium, EPIC-CVD Consortium, ExomeBP Consortium, Global Lipids Genetic Consortium, GoT2D Genes Consortium, InterAct, ReproGen Consortium, T2D-Genes Consortium, MAGIC Investigators
Body-fat distribution is a risk factor for adverse cardiovascular health consequences. We analyzed the association of body-fat distribution, assessed by waist-to-hip ratio adjusted for body mass index, with 228,985 predicted coding and splice site va
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6d155e55cab6201548d4294b6f7a099b