Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Brodesser, A."'
Autor:
Svenja Sydor, Andreas Jähnert, C Wenning, Ramiro Vilchez-Vargas, Yulia A. Nevzorova, Alexander Link, Christina Lucas, Ali Canbay, Klaas Nico Faber, S Assmuth, Susanne Brodesser, Han Moshage, Mustafa Porsch-Özcürümez, Francisco Javier Cubero, P Manka, Anja Figge, Guido Gerken, Lars P. Bechmann
Publikováno v:
Clinical Nutrition, 40(5), 2609-2619. Churchill Livingstone
Background & aims Regular consumption of fast-food (FF) as a form of typical Western style diet is associated with obesity and the metabolic syndrome, including its hepatic manifestation nonalcoholic fatty liver disease. Currently, it remains unclear
Autor:
Lukas Stüker, Hannah L. Tumbrink, Silvia von Karstedt, H. Christian Reinhardt, Ariadne Androulidaki, Susanne Brodesser, Armin Khonsari, Fatma Parmaksiz, Marcel A. Dammert, Julie George, Anna Schmitt, Filippo Beleggia, Zhiyi Chen, Christina M. Bebber, Jan Riemer, Roman K. Thomas, Jenny Stroh, Emily S. Thomas, Michaela N. Höhne, Martin L. Sos, Cleidson de Pádua Alves
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-19 (2021)
Nature Communications
Nature Communications
Loss of TP53 and RB1 in treatment-naïve small cell lung cancer (SCLC) suggests selective pressure to inactivate cell death pathways prior to therapy. Yet, which of these pathways remain available in treatment-naïve SCLC is unknown. Here, through sy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a4384638d205464ab764bd6e31a79aa
https://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&origin=inward&scp=85103983662
https://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&origin=inward&scp=85103983662
Akademický článek
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Publikováno v:
Molecular Metabolism, Vol 54, Iss, Pp 101335-(2021)
Molecular Metabolism
Molecular Metabolism
Objective An increased ω6/ω3-polyunsaturated fatty acid ratio in the current Western diet is regarded as a critical epigenetic nutritional factor in the pathogenesis of several human lifestyle diseases, metabolic syndrome, cardiovascular disease, t
Phosphoproteomics of the developing heart identifies PERM1 - An outer mitochondrial membrane protein
Autor:
Thomas Braun, Theresa Bock, Susanne Brodesser, Philipp Hammerschmidt, Sriram Aravamudhan, Tim König, Ramesh K. Krishnan, Dieu Hien Rozsivalova, Franziska Lang, Marcus Krüger, Clara Türk, Aleksandra Trifunovic, Jens C. Brüning, Lena Keufgens, Natalie Schindler, Elena I. Rugarli, Thomas Langer, Hendrik Nolte
Publikováno v:
J Mol Cell Cardiol
Heart development relies on PTMs that control cardiomyocyte proliferation, differentiation and cardiac morphogenesis. We generated a map of phosphorylation sites during the early stages of cardiac postnatal development in mice; we quantified over 10,
Autor:
Georg Auburger, Susanne Brodesser, Zeynep-Ece Kaya, Júlia Canet-Pons, Aleksandar Arsovic, Carola Oberschmidt, Nesli-Ece Sen, Suzana Gispert, Konrad Sandhoff, Melanie-Vanessa Halbach, David Meierhofer
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 23, p 5854 (2019)
International Journal of Molecular Sciences
Volume 20
Issue 23
International Journal of Molecular Sciences
Volume 20
Issue 23
Ataxin-2 (human gene symbol ATXN2) acts during stress responses, modulating mRNA translation and nutrient metabolism. Ataxin-2 knockout mice exhibit progressive obesity, dyslipidemia, and insulin resistance. Conversely, the progressive ATXN2 gain of
Autor:
Alexander Jais, Sabine A. Eming, Axel Roers, Susanne Brodesser, Jens C. Brüning, Wilhelm Bloch, Sebastian Willenborg, Xiaolei Ding, Sara A. Wickström, Markus A. Rüegg, Prerana Wagle, Michael N. Hall
Publikováno v:
J Allergy Clin Immunol
Background: Perturbation of epidermal barrier formation will profoundly compromise overall skin function, leading to a dry and scaly, ichthyosis-like skin phenotype that is the hallmark of a broad range of skin diseases, including ichthyosis, atopic
Autor:
Olaf Utermöhlen, Bettina Tosetti, Susanne Brodesser, Frederik Tellkamp, Ulrike Karow, Franziska Peters, E. Wachsmuth, Martin Krönke, Wilhelm Bloch, Carien M. Niessen
Publikováno v:
Journal of Investigative Dermatology. 140:1927-1937.e5
Epidermal barrier dysfunction is associated with a wide range of highly prevalent inflammatory skin diseases. However, the molecular processes that drive epidermal barrier maintenance are still largely unknown. Here, using quantitative proteomics, li
Local Fatty Acid Channeling into Phospholipid Synthesis Drives Phagophore Expansion during Autophagy
Publikováno v:
Autophagy
Cell
Cell
Autophagy is a conserved catabolic homeostasis process central for cellular and organismal health. During autophagy, small single-membrane phagophores rapidly expand into large double-membrane autophagosomes to encapsulate diverse cargoes for degrada
Autor:
Rashid, T., Nemazanyy, I., Paolini, C., Tatsuta, T., Crespin, P., de Villeneuve, D., Brodesser, S., Benit, P., Rustin, P., Baraibar, M., Agbulut, O., Olivier, A., Protasi, F., Langer, T., Chrast, R., de Lonlay, P., de Foucauld, H., Blaauw, B., Pende, M.
Publikováno v:
The EMBO Journal
EMBO J
EMBO J
As a consequence of impaired glucose or fatty acid metabolism, bioenergetic stress in skeletal muscles may trigger myopathy and rhabdomyolysis. Genetic mutations causing loss of function of the LPIN1 gene frequently lead to severe rhabdomyolysis bout