Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Carlo Gambacorti-Passerini"'
Autor:
Tim H. Brümmendorf, Hagop M. Kantarjian, Fiona An, Jorge E. Cortes, Carlo Gambacorti-Passerini, Eric Leip, Michael J. Mauro, Sonja Nick
Publikováno v:
European journal of haematologyREFERENCES. 106(6)
Introduction: Long-term follow-up (≥4years) demonstrated a low incidence of cardiac and vascular treatment-emergent adverse events (TEAEs) with bosutinib treatment. We evaluated cardiac, vascular, hypertension, and effusion TEAEs after≥7years of
Autor:
Christy Guyan, Mauricette Michallet, Rüdiger Hehlmann, Catherine Davis, Ronald Paquette, Carlo Gambacorti-Passerini, Clara Chen, Ginny P Sen, Stuart L. Goldberg
Publikováno v:
European Journal of Haematology
Objectives: SIMPLICITY (NCT01244750) is an observational study of patients with chronic-phase chronic myeloid leukemia (CP-CML) in routine clinical practice receiving first-line tyrosine kinase inhibitors (TKIs). We evaluated TKI treatment changes an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00833526e3e637d81cda9562ee4bb169
http://hdl.handle.net/10281/302184
http://hdl.handle.net/10281/302184
Autor:
Francesco Zaja, Filippo Gherlinzoni, Anna Maria Scattolin, Luca Arcaini, Roberto Cairoli, Mario Luppi, Carmen Fava, Patrizia Zappasodi, Matteo G. Della Porta, Monica Bocchia, Valeria Cardinali, Nicola Stefano Fracchiolla, Francesco Passamonti, Giuseppe Visani, M. Ladetto, Enrico Derenzini, Lorenza Bertù, Roberto Mina, Daniele Armiento, B. Mora, Anna Candoni, Alessandro Corso, A. M. Vannucchi, Paolo Corradini, Francesco Lanza, Pellegrino Musto, Agostino Tafuri, Carlo Visco, E. Coviello, Francesco Marchesi, Roberto M. Lemoli, Chiara Cattaneo, Alessandro Busca, Marco Salvini, Sara Galimberti, I. Romano, M. Merli, Mauro Krampera, Alessandra Romano, Paolo Grossi, Michele Cavo, E. O. La Barbera, Mauro Turrini, Livio Pagano, Adriano Venditti, Antonio Pinto, Patrizia Tosi, F. Farina, Riccardo Bruna, L. Petrucci, Massimo Massaia, Monia Marchetti, Carlo Gambacorti Passerini, Francesco Merli
Publikováno v:
British Journal of Haematology
COVID-19 is associated with high mortality in patients with haematological malignancies (HM) and rate of seroconversion is unknown. The ITA-HEMA-COV project (NCT04352556) investigated patterns of seroconversion for SARS-CoV-2 IgG in patients with HMs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c24e55fe48b3d774cb35c102c1385a57
http://hdl.handle.net/11368/2994480
http://hdl.handle.net/11368/2994480
Autor:
Francesca Fanelli, Steen Larsen, Stefania Citterio, Lisa Marie Røst, Roberta Corti, Barbara Crescenzi, Mattia Docci, Deborah D'Aliberti, Mi Jang, Delphine Rea, Rocco Piazza, Clizia Chinello, Mayla Bertagna, Guido Cavaletti, Fulvio Magni, Antonio Niro, M Bossi, Ilaria Crespiatico, Rossella Renso, Carlo Gambacorti-Passerini, Giovanni Zambrotta, Francesco Mantegazza, Domenico Salerno, Luca Massimino, Mario Mauri, Per Bruheim, Luca Nardo, Valeria Cassina, Cristina Mecucci, Diletta Fontana
Publikováno v:
Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
Fontana, D, Mauri, M, Renso, R, Docci, M, Crespiatico, I, Røst, L M, Jang, M, Niro, A, D’aliberti, D, Massimino, L, Bertagna, M, Zambrotta, G, Bossi, M, Citterio, S, Crescenzi, B, Fanelli, F, Cassina, V, Corti, R, Salerno, D, Nardo, L, Chinello, C, Mantegazza, F, Mecucci, C, Magni, F, Cavaletti, G, Bruheim, P, Rea, D, Larsen, S, Gambacorti-passerini, C & Piazza, R 2020, ' ETNK1 mutations induce a mutator phenotype that can be reverted with phosphoethanolamine ', Nature Communications, vol. 11, no. 1, 5938 . https://doi.org/10.1038/s41467-020-19721-w
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
Fontana, D, Mauri, M, Renso, R, Docci, M, Crespiatico, I, Røst, L M, Jang, M, Niro, A, D’aliberti, D, Massimino, L, Bertagna, M, Zambrotta, G, Bossi, M, Citterio, S, Crescenzi, B, Fanelli, F, Cassina, V, Corti, R, Salerno, D, Nardo, L, Chinello, C, Mantegazza, F, Mecucci, C, Magni, F, Cavaletti, G, Bruheim, P, Rea, D, Larsen, S, Gambacorti-passerini, C & Piazza, R 2020, ' ETNK1 mutations induce a mutator phenotype that can be reverted with phosphoethanolamine ', Nature Communications, vol. 11, no. 1, 5938 . https://doi.org/10.1038/s41467-020-19721-w
Recurrent somatic mutations in ETNK1 (Ethanolamine-Kinase-1) were identified in several myeloid malignancies and are responsible for a reduced enzymatic activity. Here, we demonstrate in primary leukemic cells and in cell lines that mutated ETNK1 cau
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9daa2965213b7e056a4bf82b15332df7
http://hdl.handle.net/10281/298474
http://hdl.handle.net/10281/298474
Autor:
Alessandro Sessa, Luca Massimino, Marc Baumann, Fabio Stagno, Sara Redaelli, Francesco Onida, Francesco Passamonti, Emilio Usala, Delphine Rea, Leonardo Campiotti, Alicia Rubio, Alessandra Pirola, Vera Magistroni, Bruno Martino, Michele Merli, Vania Broccoli, Mario Mauri, Maciej Lalowski, Marco Peronaci, Marco Bregni, Rabah Soliymani, Alessandro Morotti, Rocco Piazza, Carlo Gambacorti-Passerini, Federica Banfi, Francesca Pavesi, Caterina Mezzatesta
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
Nature Communications
Nature Communications
SETBP1 variants occur as somatic mutations in several hematological malignancies such as atypical chronic myeloid leukemia and as de novo germline mutations in the Schinzel–Giedion syndrome. Here we show that SETBP1 binds to gDNA in AT-rich promote
Autor:
Bernhard Gentner, Ilaria M. Michelozzi, Carmelo Rizzari, Chiara Tomasoni, Marta Serafini, Francesco Dazzi, Tiziana Coliva, Valentina Granata, Giada De Ponti, Andrea Biondi, Carlo Gambacorti-Passerini, Laura Antolini, Alice Pievani, Gaia Alberti
Publikováno v:
British Journal of Haematology
British Journal of Haematology, 186(3), 397-399. Wiley-Blackwell
Kaspers, G J L 2019, ' Acute myeloid leukaemia niche regulates response to L-asparaginase ', British Journal of Haematology, vol. 186, no. 3, pp. 397-399 . https://doi.org/10.1111/bjh.15924
British Journal of Haematology, 186(3), 397-399. Wiley-Blackwell
Kaspers, G J L 2019, ' Acute myeloid leukaemia niche regulates response to L-asparaginase ', British Journal of Haematology, vol. 186, no. 3, pp. 397-399 . https://doi.org/10.1111/bjh.15924
Eradicating the malignant stem cell is the ultimate challenge in the treatment of leukaemia. Leukaemic stem cells (LSC) hijack the normal haemopoietic niche, where they are mainly protected from cytotoxic drugs. The anti-leukaemic effect of L-asparag
Autor:
Caterina Mezzatesta, David T Yeung, Miriam Nava, Alessandro Morotti, Carlo Gambacorti-Passerini, Jacqueline Boultwood, Deborah D'Aliberti, Roberta Rigolio, Luca Massimino, Wendy T Parker, Rocco Piazza, Diletta Fontana, Alessandra Pirola, Sara Readelli, Dong-Wook Kim, Nitesh Sharma, Andreas W. Schreiber, Mario Mauri, Ilaria Crespiatico, Susan Branford, Vera Magistroni, Giuseppe Saglio, R Perego, Praveen Khandelwal, Michela Viltadi, Paul Wang, Silvia Bombelli, Stefania Citterio
Publikováno v:
Haematologica
Despite the advent of tyrosine kinase inhibitors, a proportion of chronic myeloid leukemia patients in chronic phase fails to respond to Imatinib or to second generation inhibitors and progress to blast crisis. Limited improvements in the understandi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::edd0137ab0ca425dfe8ea9490aff4a1e
http://hdl.handle.net/10281/230164
http://hdl.handle.net/10281/230164
Autor:
Dennis Dong Hwan Kim, Jane F. Apperley, Christopher A. Eide, Georgios Nteliopoulos, Sin Tiong Ong, Jerry Radich, Francois-Xavier Mahon, Jorge E. Cortes, Brian J. Druker, Satu Mustjoki, Michael J. Mauro, Charles Chuah, Susan Branford, Carlo Gambacorti-Passerini, Timothy P. Hughes, Thomas Ernst, Dong-Kee Kim, A. Hochhaus
Outcomes for patients with chronic myeloid leukemia (CML) have substantially improved due to advances in drug development and rational treatment intervention strategies. Despite these significant advances there are still unanswered questions on patie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c12ae3824a105d89fad1c5496061257
https://hdl.handle.net/11541.2/137800
https://hdl.handle.net/11541.2/137800
Autor:
Jorge E. Cortes, Jerald P. Radich, Jane F. Apperley, George Q. Daley, Michael W. Deininger, Christine J. Harrison, Tariq I. Mughal, Carlo Gambacorti-Passerini, Giuseppe Saglio, Timothy P. Hughes
Publikováno v:
Haematologica. 101:541-558
© 2016 Ferrata Storti Foundation.With the deaths of Janet Rowley and John Goldman in December 2013, the world lost two pioneers in the field of chronic myeloid leukemia. In 1973, Janet Rowley, unraveled the cytogenetic anatomy of the Philadelphia ch
Publikováno v:
American Journal of Hematology. 91:67-75
The efficacy of second-line treatment for chronic myeloid leukemia (CML) plays an important role in allowing CML patients to enjoy a normal life expectancy. Four tyrosine kinase inhibitors (TKIs) are presently available: bosutinib, dasatinib, nilotin