Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Barry T. Rouse"'
Publikováno v:
J Virol
This report evaluates a dietary manipulation approach to suppress the severity of ocular infections caused by herpes simplex virus infection. The virus causes chronic damage to the cornea that results from a T-cell-orchestrated inflammatory reaction
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8651095e71949b6d37857fa95cf569bf
https://avesis.erciyes.edu.tr/publication/details/029d458e-3710-4662-9f70-2853447a1664/oai
https://avesis.erciyes.edu.tr/publication/details/029d458e-3710-4662-9f70-2853447a1664/oai
Publikováno v:
Mucosal immunology
This report deals with the possible mechanism by which IL-18 can contribute to the control and resolution of inflammatory lesions in the cornea caused by herpes simplex virus infection. Our results demonstrate that the expression of the IL-18R by bot
Autor:
Barry T. Rouse, Naveen K. Rajasagi
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Frontiers in Immunology
Frontiers in Immunology
The blinding inflammatory lesion stromal keratitis (SK), which occurs in some patients in response to ocular herpes simplex virus (HSV) infection, represents mainly an immune cell mediated inflammatory response to the virus infection. The principal o
Autor:
Siva Karthik Varanasi, Pranay Dogra, Ujjaldeep Jaggi, M. Lorena Harvey, Fernanda Gimenez, Barry T. Rouse, Siddheshvar Bhela
Publikováno v:
Journal of Leukocyte Biology. 99:647-657
Herpes simplex 1 infection of the eye can cause blindness with lesions in the corneal stroma largely attributable to inflammatory events that include components of both adaptive and innate immunity. Several innate immune responses are triggered by he
Publikováno v:
Microbes and infection. 20(6)
Ocular infection with herpes simplex virus (HSV) can result in a chronic immune inflammatory lesion that is a significant cause of human blindness. A key to controlling stromal keratitis (SK) lesion severity is to identify cellular and molecular even
Autor:
Barry T. Rouse, Naveen K. Rajasagi
Publikováno v:
Microbes and infection. 20(9-10)
HSV-1 ocular infection can cause herpes stromal keratitis (SK), an immunopathological lesion. Frequent recurrences can lead to progressive corneal scaring which can result in vision impairment if left untreated. Currently, the acute and epithelial fo
Autor:
Siddheshvar Bhela, Sachin Mulik, John Xu, Siva Karthik Varanasi, Barry T. Rouse, Fernanda Gimenez, Patrick Y. Lu, Ujjaldeep Jaggi, Raphael L. Richardson, Pradeep B. J. Reddy
Publikováno v:
The American Journal of Pathology. 185:1073-1084
Ocular infection with herpes simplex virus 1 can result in a chronic immunoinflammatory stromal keratitis (SK) lesion that is a significant cause of human blindness. A key to controlling SK lesion severity is to identify cellular and molecular events
Autor:
Sarah S. Sloan, Naveen K. Rajasagi, Barry T. Rouse, Ujjaldeep Jaggi, Siddheshvar Bhela, Siva Karthik Varanasi
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 199(4)
Ocular infection with HSV causes a chronic T cell–mediated inflammatory lesion in the cornea. Lesion severity is affected by the balance of different CD4 T cell subsets, with greater severity occurring when the activity of regulatory T cells (Tregs
Publikováno v:
Journal of leukocyte biology. 102(5)
Stromal keratitis (SK) is a chronic immunopathological lesion of the eye, caused by HSV-1 infection, and a common cause of vision impairment in humans. The inflammatory lesions in the cornea are primarily caused by neutrophils with the active partici
Autor:
Barry T. Rouse, Pradeep B. J. Reddy, John Xu, Shalini Sharma, Patrick Y. Lu, Sachin Mulik, Fernanda Gimenez, Naveen K. Rajasagi
Publikováno v:
The American Journal of Pathology. 181(2):525-534
MicroRNAs (miRNAs) are small regulatory molecules that control diverse biological processes that include angiogenesis. Herpes simplex virus (HSV) causes a chronic immuno-inflammatory response in the eye that may result in corneal neovascularization d