Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Hae-Won Uh"'
Autor:
Fernanda L. Paganelli, Malbert R. C. Rogers, James A. Groot, Danielle Adriaans, Marc J. M. Bonten, Roos-Marijn Berbers, Rob J. L. Willems, Misha Luyer, Helen L. Leavis, C. Marijn Hazelbag, Hae-Won Uh, Ad C. Fluit, Antoni P. A. Hendrickx, Marco C. Viveen
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-8 (2019)
Scientific Reports, 9(1). Nature Publishing Group
Scientific Reports
Scientific Reports, 9(1). Nature Publishing Group
Scientific Reports
Bariatric surgery in morbid obesity, either through sleeve gastrectomy (SG) or Roux-Y gastric bypass (RYGB), leads to sustainable weight loss, improvement of metabolic disorders and changes in intestinal microbiota. Yet, the relationship between chan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a11657d1b4293f418ab79086eb0cf0cc
https://dspace.library.uu.nl/handle/1874/384753
https://dspace.library.uu.nl/handle/1874/384753
Autor:
P. Eline Slagboom, L. Renee Ruhaak, Rosina Plomp, Manfred Wuhrer, Marian Beekman, Hae-Won Uh, Maurice H. J. Selman, Jeanine J. Houwing-Duistermaat, Karli R. Reiding
Publikováno v:
Scientific Reports, 7
Scientific Reports
Scientific Reports, Vol 7, Iss 1, Pp 1-10 (2017)
Scientific Reports
Scientific Reports, Vol 7, Iss 1, Pp 1-10 (2017)
This study indicates that glycosylation of immunoglobulin G, the most abundant antibody in human blood, may convey useful information with regard to inflammation and metabolic health. IgG occurs in the form of different subclasses, of which the effec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f78e035ebc31dab7f3c603651a5a551
http://hdl.handle.net/1887/114813
http://hdl.handle.net/1887/114813
Publikováno v:
BMC Proceedings
BMC Proceedings, Vol 5, Iss Suppl 9, p S90 (2011)
BMC Proceedings, Vol 5, Iss Suppl 9, p S90 (2011)
Analyzing sequencing data is difficult because of the low frequency of rare variants, which may result in low power to detect associations. We consider pathway analysis to detect multiple common and rare variants jointly and to investigate whether an
Publikováno v:
BMC Proceedings, Vol 5, Iss Suppl 9, p S22 (2011)
BMC Proceedings
BMC Proceedings
Recently we proposed a novel two-step approach to test for pathway effects in disease progression. The goal of this approach is to study the joint effect of multiple single-nucleotide polymorphisms that belong to certain genes. By using random effect
Autor:
Hae-Won Uh, Paul H. C. Eilers
Publikováno v:
PLoS ONE
PLoS ONE, Vol 6, Iss 9, p e24219 (2011)
PLoS One (print), 6(9). Public Library of Science
PLoS ONE, 6(9)
PLoS ONE, Vol 6, Iss 9, p e24219 (2011)
PLoS One (print), 6(9). Public Library of Science
PLoS ONE, 6(9)
The Composite Link Model is a generalization of the generalized linear model in which expected values of observed counts are constructed as a sum of generalized linear components. When combined with penalized likelihood, it provides a powerful and el
Publikováno v:
BMC Proceedings
BMC Proceedings, Vol 3, Iss Suppl 7, p S123 (2009)
BMC Proceedings, Vol 3, Iss Suppl 7, p S123 (2009)
We investigated efficient case-control association analysis using family data. The outcome of interest was coronary heart disease. We employed existing and new methods that take into account the correlations among related individuals to obtain the pr
Autor:
Hae-Won Uh, Bart Mertens, Hein Putter, Hans C. van Houwelingen, Henk Jan van der Wijk, Jeanine J Houwing-Duistermaat
Publikováno v:
BMC Proceedings, Vol 1, Iss Suppl 1, p S114 (2007)
BMC Proceedings
BMC Proceedings
Our aim is to develop methods for identifying a (causal) variant or variants from a dense panel of single-nucleotide polymorphisms (SNPs) that are genotyped on the evidence of previous studies. Because a large number of SNPs are in close proximity to
A new score statistic to test for association given linkage in affected sibling pair-control designs
Publikováno v:
BMC Proceedings
BMC Proceedings, Vol 1, Iss Suppl 1, p S39 (2007)
BMC Proceedings, Vol 1, Iss Suppl 1, p S39 (2007)
To detect association of the DR1 allele with rheumatoid arthritis (RA) given linkage in the affected sibling pairs of the replicates of Problem 3 of Genetic Analysis Workshop 15 (GAW15), we propose a new score statistic that takes into account the li
Autor:
Yosef Safi Harb, Hae-Won Uh, Nico Curti, Gastone Castellani, Folkert W. Asselbergs, Lorenzo Dall'Olio, Daniel Remondini
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Scientific Reports
Scientific reports, 10(1). Nature Publishing Group
Scientific Reports
Scientific reports, 10(1). Nature Publishing Group
Photoplethysmography (PPG) measured by smartphone has the potential for a large scale, non-invasive, and easy-to-use screening tool. Vascular aging is linked to increased arterial stiffness, which can be measured by PPG. We investigate the feasibilit
Publikováno v:
BMC Proceedings, Vol 3, Iss Suppl 7, p S97 (2009)
BMC Proceedings
BMC Proceedings
Our aim is to develop methods for mapping genes related to age at onset in general pedigrees. We propose two score tests, one derived from a gamma frailty model with pairwise likelihood and one derived from a log-normal frailty model with approximate