Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Ena Wang"'
Autor:
Wei Liu, Lotfi Chouchane, Aouatef Ismail Chouchane, Valeria De Giorgi, Rebecca Mathew, Davide Bedognetti, Konduru S Sastry, Sara Tomei, Daniela Murtas, Lee Silcock, Francesco M. Marincola, Ena Wang, Nicola James, Muna Al Hashmi, Ramzi Temanni, Valentina Mattei, Barbara Seliger
Publikováno v:
Journal of Translational Medicine
Journal of Translational Medicine, Vol 18, Iss 1, Pp 1-9 (2020)
Journal of Translational Medicine, Vol 18, Iss 1, Pp 1-9 (2020)
Background Most mutations in melanoma affect one critical amino acid on BRAF gene, resulting in the V600E substitution. Patient management is often based on the use of specific inhibitors targeting this mutation. Methods DNA and RNA mutation status w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5efe0635c126ac8449b88895393f0f2
https://doi.org/10.21203/rs.3.rs-16973/v1
https://doi.org/10.21203/rs.3.rs-16973/v1
Autor:
Rossella Galli, Stefania Mazzoleni, Andrea Volonté, Shilpa Ravindran, Cristina Maccalli, Ena Wang, Sara Tomei
Publikováno v:
Journal of Personalized Medicine, Vol 11, Iss 264, p 264 (2021)
Journal of Personalized Medicine
Volume 11
Issue 4
Journal of Personalized Medicine
Volume 11
Issue 4
Glioblastoma (GBM) represents the most common and aggressive tumor of the brain. Despite the fact that several studies have recently addressed the molecular mechanisms underlying the disease, its etiology and pathogenesis are still poorly understood.
Autor:
Valentina Mattei, Ramzi Temanni, Rebecca Mathew, Davide Bedognetti, Lee Silcock, Barbara Seliger, Rashid Al-Ali, Ena Wang, Francesca Lessi, Sara Tomei, Puthen V. Jithesh, Hakeem Almabrazi, Francesco M. Marincola, Muna Al-Hashmi, Nicola James, Younes Mokrab
Publikováno v:
Journal of Translational Medicine
Journal of Translational Medicine, Vol 17, Iss 1, Pp 1-7 (2019)
Journal of Translational Medicine, Vol 17, Iss 1, Pp 1-7 (2019)
Background Monoallelic expression (MAE) is a frequent genomic phenomenon in normal tissues, however its role in cancer is yet to be fully understood. MAE is defined as the expression of a gene that is restricted to one allele in the presence of a dip
Autor:
Corrado Caracò, Claus Garbe, Gennaro Ciliberto, Sanjiv S. Agarwala, Janice M. Mehnert, Nicola Mozzillo, Francesco M. Marincola, Paolo A. Ascierto, Thomas F. Gajewski, Soldano Ferrone, Giuseppe Masucci, Ena Wang, Reinhard Dummer, Magdalena Thurin, Gerardo Botti, Michael A. Postow, Giuseppe Palmieri, Jason J. Luke, Michael A. Davies, Igor Puzanov, Carlo Bifulco, Stephen P. Schoenberger
Publikováno v:
Journal of translational medicine (Online) 16 (2018). doi:10.1186/s12967-018-1568-6
info:cnr-pdr/source/autori:Ascierto, Paolo A.; Puzanov, Igor; Agarwala, Sanjiv S.; Bifulco, Carlo; Botti, Gerardo; Caraco, Corrado; Ciliberto, Gennaro; Davies, Michael A.; Dummer, Reinhard; Ferrone, Soldano; Gajewski, Thomas F.; Garbe, Claus; Luke, Jason J.; Marincola, Francesco M.; Masucci, Giuseppe; Mehnert, Janice M.; Mozzillo, Nicola; Palmieri, Giuseppe; Postow, Michael A.; Schoenberger, Stephen P.; Wang, Ena; Thurin, Magdalena/titolo:Perspectives in melanoma: Meeting report from the Melanoma Bridge (30 November-2 December, 2017, Naples, Italy)/doi:10.1186%2Fs12967-018-1568-6/rivista:Journal of translational medicine (Online)/anno:2018/pagina_da:/pagina_a:/intervallo_pagine:/volume:16
Journal of Translational Medicine, Vol 16, Iss 1, Pp 1-13 (2018)
Journal of Translational Medicine
info:cnr-pdr/source/autori:Ascierto, Paolo A.; Puzanov, Igor; Agarwala, Sanjiv S.; Bifulco, Carlo; Botti, Gerardo; Caraco, Corrado; Ciliberto, Gennaro; Davies, Michael A.; Dummer, Reinhard; Ferrone, Soldano; Gajewski, Thomas F.; Garbe, Claus; Luke, Jason J.; Marincola, Francesco M.; Masucci, Giuseppe; Mehnert, Janice M.; Mozzillo, Nicola; Palmieri, Giuseppe; Postow, Michael A.; Schoenberger, Stephen P.; Wang, Ena; Thurin, Magdalena/titolo:Perspectives in melanoma: Meeting report from the Melanoma Bridge (30 November-2 December, 2017, Naples, Italy)/doi:10.1186%2Fs12967-018-1568-6/rivista:Journal of translational medicine (Online)/anno:2018/pagina_da:/pagina_a:/intervallo_pagine:/volume:16
Journal of Translational Medicine, Vol 16, Iss 1, Pp 1-13 (2018)
Journal of Translational Medicine
Metastatic melanoma represents a challenging clinical situation and, until relatively recently, there was an absence of effective treatment options. However, in 2011, the advanced melanoma treatment landscape was revolutionised with the approval of t
Autor:
Jessica Roelands, Julie Decock, Sabri Boughorbel, Darawan Rinchai, Cristina Maccalli, Michele Ceccarelli, Michael Black, Cris Print, Jeff Chou, Scott Presnell, Charlie Quinn, Puthen Jithesh, Najeeb Syed, Salha B.J. Al Bader, Shahinaz Bedri, Ena Wang, Francesco M. Marincola, Damien Chaussabel, Peter Kuppen, Lance D. Miller, Davide Bedognetti, Wouter Hendrickx
Publikováno v:
F1000Research, Vol 6 (2018)
The increased application of high-throughput approaches in translational research has expanded the number of publicly available data repositories. Gathering additional valuable information contained in the datasets represents a crucial opportunity in
Autor:
Igor Puzanov, Giuseppe Masucci, Janis M. Taube, Alexander M.M. Eggermont, Bernard A. Fox, Ena Wang, Paolo A. Ascierto, Michael A. Postow, Sanjiv S. Agarwala, Gennaro Ciliberto, Alessandra Cesano, Francesco M. Marincola, Sandra Demaria, Kevin K. Dobbin, Magdalena Thurin, Lisa Villabona, Paul M. Sondel, Jennifer A. Wargo, Lisa H. Butterfield
Publikováno v:
Journal of Translational Medicine
Journal of Translational Medicine, Vol 15, Iss 1, Pp 1-10 (2017)
Journal of Translational Medicine, Vol 15, Iss 1, Pp 1-10 (2017)
Immunotherapies have emerged as one of the most promising approaches to treat patients with cancer. Recently, the entire medical oncology field has been revolutionized by the introduction of immune checkpoints inhibitors. Despite success in a variety
Autor:
Shira Perl, Angelique Biancotto, J. Christopher Fuchs, Marc Langweiler, Abigail Wank, Wendell Cook, Ena Wang, Pradeep K. Dagur, J. Philip McCoy, Matthew J. Olnes
Publikováno v:
PLoS ONE
PLoS ONE, Vol 8, Iss 12, p e76091 (2013)
PLoS ONE, Vol 8, Iss 12, p e76091 (2013)
Background Cytokines are humoral molecules that elicit regulatory function in immunologic pathways. The level and type of cytokine production has become critical in distinguishing physiologic from pathologic immune conditions. Cytokine profiling has
Autor:
Luigi Buonaguro, Francesco M. Marincola, Maria Lina Tornesello, Francesco Izzo, Andrea Worschech, Ena Wang, Franco M. Buonaguro, Valeria De Giorgi
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e56153 (2013)
PLoS ONE
PLoS ONE
Hepatocellular carcinomas (HCCs) are a heterogeneous group of tumors that differ in risk factors and genetic alterations. In Italy, particularly Southern Italy, chronic hepatitis C virus (HCV) infection represents the main cause of HCC. Using high-de
Autor:
Ena Wang
Publikováno v:
Journal of Translational Medicine
Journal of Translational Medicine, Vol 10, Iss Suppl 2, p A44 (2012)
Journal of Translational Medicine, Vol 10, Iss Suppl 2, p A44 (2012)
A cancer immune signature implicating good prognosis and responsiveness to immunotherapy was described that is observed also in other aspects of immune-mediated, tissue-specific destruction (TSD). Its determinism remains, however, elusive. On one sid
Autor:
John M. Kirkwood, Yingdong Zhao, Francesco M. Marincola, Helen Gogas, Maria Spyropoulou-Vlachou, Monica C. Panelli, Alessandro Monaco, Lorenzo Uccellini, Ena Wang
Publikováno v:
PLoS ONE
PLoS ONE, Vol 7, Iss 7, p e40805 (2012)
PLoS ONE, Vol 7, Iss 7, p e40805 (2012)
PURPOSE: IFNa was the first cytokine to demonstrate anti-tumor activity in advanced melanoma. Despite the ability of high-dose IFNa reducing relapse and mortality by up to 33%, large majority of patients experience side effects and toxicity which out