Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Luca, C."'
Autor:
Matteo Santucci, Godefridus J. Peters, Outi M. H. Salo-Ahen, Domenico D'Arca, Matteo Trande, Angela L, Rosaria Luciani, Gabriele Cruciani, Rimessi A, Maria Paola Costi, Silvia Franchini, Cecilia Pozzi, Elisa Giovannetti, Antonio Quotadamo, Stefania Ferrari, Gaia G, Alberto Venturelli, Lorena Losi, Nuno Santarém, Daniela Cardinale, Gaetano Marverti, Emanuele C, Giuseppe Cannazza, Pacifico S, Silvia A, Pasquale Linciano, Stefan H, Anabela Cordeiro-da-Silva, Rebecca C. Wade, Robert M. Stroud, Remo Guerrini, Luca C, Pinton P, Stefano Mangani, Filippo Genovese, Puneet Saxena, Glauco Ponterini
Drugs that target human thymidylate synthase (hTS) are widely used in anti-cancer therapy. However, treatment with classical substrate-site-directed TS inhibitors induces its over-expression and the development of drug resistance. We thus pursued an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ce83876e0c9d189d2098a93bb2e55ed
https://doi.org/10.26434/chemrxiv.14156918.v1
https://doi.org/10.26434/chemrxiv.14156918.v1
Autor:
Jake Dunning, Samuel Bremang, R. Varro, Vetkar A, Dustan S, Derqui-Fernandez N, Graham P. Taylor, J. Fenn, R. Kundu, Quinn, Hammett S, Ajit Lalvani, Joanna Ellis, J. S. Narean, Koycheva A, David C. Jackson, Timesh D Pillay, Miah S, Anjna Badhan, Emily Conibear, Andre Charlett, Hakki S, Wendy S. Barclay, Madon Kj, Hamish Houston, Samuel J, Anderson C, Paul S. Freemont, C. Tejpal, Angie Lackenby, Maria Zambon, Cutajar J, Jake Barnett, Michael A. Crone, Whitfield Mg, McDermott E, Luca C, Neil M. Ferguson, Shazaad Ahmad, Aran Singanayagam
Publikováno v:
SSRN Electronic Journal.
Background: The SARS-CoV-2 Delta variant is highly transmissible and spreading globally but a detailed understanding of community transmission risks in highly vaccinated populations is lacking. Methods: Between September 2020 and August 2021, we recr
Autor:
Luca C. Stockhausen, David Neely, Nicholas P. Dover, Satyabrata Kar, Paul McKenna, G. Hicks, Ian Musgrave, Ross Gray, H. W. Powell, H. Padda, R. J. Clarke, Ricardo Torres, M. King, Zulfikar Najmudin, Bruno Izquierdo, Dean Rusby, David Carroll, D. A. MacLellan, Marco Borghesi
Publikováno v:
King, M, Gray, R J, Powell, H W, MacLellana, D A, Gonzalez-Izquierdo, B, Stockhausen, L C, Hicks, G S, Dover, N P, Rusby, D R, Carroll, D C, Padda, H, Torres, R, Kar, S, Clarke, R J, Musgrave, I O, Najmudin, Z, Borghesi, M, Neely, D & McKenna, P 2016, ' Ion acceleration and plasma jet formation in ultra-thin foils undergoing expansion and relativistic transparency ', Nuclear Instruments & Methods in Physics Research-Section A: Accelerators, Spectrometers, Detectors, and Associated Equipment, vol. 829, pp. 163-166 . https://doi.org/10.1016/j.nima.2016.02.032
At sufficiently high laser intensities, the rapid heating to relativistic velocities and resulting decompression of plasma electrons in an ultra-thin target foil can result in the target becoming relativistically transparent to the laser light during
Publikováno v:
GREDOS: Repositorio Institucional de la Universidad de Salamanca
Universidad de Salamanca (USAL)
GREDOS. Repositorio Institucional de la Universidad de Salamanca
instname
Universidad de Salamanca (USAL)
GREDOS. Repositorio Institucional de la Universidad de Salamanca
instname
The Spanish Pulsed Laser Centre (CLPU) is a new high-power laser facility for users. Its main system,VEGA, is a CPA Ti:Sapphire laser which, in itsfinal phase, will be able to reach Petawatt peak powers inpulses of 30 fs with a pulse contrast of 1:10
Autor:
R. J. Dance, David Neely, C. D. Murphy, D. A. MacLellan, H. W. Powell, James Green, Ross Gray, Robbie Wilson, Luca C. Stockhausen, Graeme Scott, Nicola Booth, M. King, Paul McKenna, David Carroll, N. M. H. Butler, Marco Borghesi, Steve Hawkes, John McCreadie, Bruno Gonzalez-Izquierdo
Publikováno v:
Gonzalez-Izquierdo, B, Gray, R J, King, M, Wilson, R, Dance, R J, Powell, H, MacLellan, D A, McCreadie, J, Butler, N M H, Hawkes, S, Green, J S, Murphy, C D, Stockhausen, L C, Carroll, D C, Booth, N, Scott, G G, Borghesi, M, Neely, D & McKenna, P 2016, ' Influence of laser polarization on collective electron dynamics in ultraintense laser-foil interactions ', High Power Laser Science and Engineering, vol. 4, e33 . https://doi.org/10.1017/hpl.2016.35
High Power Laser Science and Engineering
High Power Laser Science and Engineering
The collective response of electrons in an ultrathin foil target irradiated by an ultraintense ( ${\sim}6\times 10^{20}~\text{W}~\text{cm}^{-2}$ ) laser pulse is investigated experimentally and via 3D particle-in-cell simulations. It is shown that if
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb1e25fc78eb6416aa7689324eca6388
https://pure.qub.ac.uk/en/publications/influence-of-laser-polarization-on-collective-electron-dynamics-in-ultraintense-laserfoil-interactions(b2285194-4209-4c85-bf2b-bbe625a3f99b).html
https://pure.qub.ac.uk/en/publications/influence-of-laser-polarization-on-collective-electron-dynamics-in-ultraintense-laserfoil-interactions(b2285194-4209-4c85-bf2b-bbe625a3f99b).html
Autor:
D. A. MacLellan, John McCreadie, James Green, C. D. Murphy, Ross Gray, Bruno Gonzalez-Izquierdo, David Neely, Marco Borghesi, Robbie Wilson, Graeme Scott, H. W. Powell, Luca C. Stockhausen, M. King, N. M. H. Butler, Steve Hawkes, David Carroll, R. J. Dance, Paul McKenna, Nicola Booth
Publikováno v:
Gonzalez-Izquierdo, B, King, M, Gray, R J, Wilson, R, Dance, R J, Powell, H, MacLellan, D A, McCreadie, J, Butler, N M H, Hawkes, S, Green, J S, Murphy, C D, Stockhausen, L C, Carroll, D C, Booth, N, Scott, G G, Borghesi, M, Neely, D & McKenna, P 2016, ' Towards optical polarization control of laser-driven proton acceleration in foils undergoing relativistic transparency ', Nature Communications, vol. 7, 12891 . https://doi.org/10.1038/ncomms12891
Nature Communications
Nature Communications, Vol 7, Iss 1, Pp 1-10 (2016)
Nature Communications
Nature Communications, Vol 7, Iss 1, Pp 1-10 (2016)
Control of the collective response of plasma particles to intense laser light is intrinsic to relativistic optics, the development of compact laser-driven particle and radiation sources, as well as investigations of some laboratory astrophysics pheno
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db44c5266775c607a82b2b30a08d6287
https://pure.qub.ac.uk/en/publications/towards-optical-polarization-control-of-laserdriven-proton-acceleration-in-foils-undergoing-relativistic-transparency(56191295-4a7a-4c0e-86ff-a90525bec790).html
https://pure.qub.ac.uk/en/publications/towards-optical-polarization-control-of-laserdriven-proton-acceleration-in-foils-undergoing-relativistic-transparency(56191295-4a7a-4c0e-86ff-a90525bec790).html
Autor:
D. A. MacLellan, Robbie Wilson, R. Capdessus, Ross Gray, Luca C. Stockhausen, David Neely, Paul McKenna, H. Padda, H. W. Powell, Xiaohui Yuan, M. King, R. J. Dance, Bruno Gonzalez-Izquierdo, David Carroll, N. M. H. Butler, Marco Borghesi
Publikováno v:
Physics of Plasmas
Padda, H, King, M, Gray, R J, Powell, H W, Gonzalez-Izquierdo, B, Stockhausen, L C, Wilson, R, Carroll, D C, Dance, R J, MacLellan, D A, Yuan, X H, Butler, N M H, Capdessus, R, Borghesi, M, Neely, D & McKenna, P 2016, ' Intra-pulse transition between ion acceleration mechanisms in intense laser-foil interactions ', Physics of Plasmas, vol. 23, no. 6, 063116 . https://doi.org/10.1063/1.4954654
Padda, H, King, M, Gray, R J, Powell, H W, Gonzalez-Izquierdo, B, Stockhausen, L C, Wilson, R, Carroll, D C, Dance, R J, MacLellan, D A, Yuan, X H, Butler, N M H, Capdessus, R, Borghesi, M, Neely, D & McKenna, P 2016, ' Intra-pulse transition between ion acceleration mechanisms in intense laser-foil interactions ', Physics of Plasmas, vol. 23, no. 6, 063116 . https://doi.org/10.1063/1.4954654
Multiple ion acceleration mechanisms can occur when an ultrathin foil is irradiated with an intense laser pulse, with the dominant mechanism changing over the course of the interaction. Measurement of the spatial-intensity distribution of the beam of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4663bc1fe7bce3adfc2967267c475de6
https://strathprints.strath.ac.uk/56621/1/Padda_etal_POP_2016_Intra_pulse_transition_between_ion_acceleration_mechanisms.pdf
https://strathprints.strath.ac.uk/56621/1/Padda_etal_POP_2016_Intra_pulse_transition_between_ion_acceleration_mechanisms.pdf
Publikováno v:
SPIE Proceedings.
The Spanish Pulsed Laser Centre (CLPU) is a new high-power laser facility for users. Its main system, VEGA, is a CPA Ti:Sapphire laser which, in its final phase, will be able to reach petawatt peak powers in pulses of 30 fs with a pulse contrast of 1
Autor:
C. D. Murphy, H. W. Powell, David Neely, Ricardo Torres, Dean Rusby, Nicola Booth, Dan Symes, Bruno Gonzalez-Izquierdo, Marco Borghesi, Robbie Wilson, S. J. Hawkes, Graeme Scott, Paul McKenna, Ross Gray, Luca C. Stockhausen, D. A. MacLellan, David Carroll
Publikováno v:
Gray, R J, MacLellan, D A, Gonzalez-Izquierdo, B, Powell, H W, Carroll, D C, Murphy, C D, Stockhausen, L C, Rusby, D R, Scott, G G, Wilson, R, Booth, N, Symes, D R, Hawkes, S J, Torres, R, Borghesi, M, Neely, D & McKenna, P 2014, ' Azimuthal asymmetry in collective electron dynamics in relativistically transparent laser-foil interactions ', New Journal of Physics, vol. 16, 093027 . https://doi.org/10.1088/1367-2630/16/9/093027
Asymmetry in the collective dynamics of ponderomotively-driven electrons in the interaction of an ultraintense laser pulse with a relativistically transparent target is demonstrated experimentally. The 2D profile of the beam of accelerated electrons
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34bb1f298178a91f8b21f91ec3122095
https://pure.qub.ac.uk/en/publications/azimuthal-asymmetry-in-collective-electron-dynamics-in-relativistically-transparent-laserfoil-interactions(6023ecfe-3baf-4a3e-9544-f72270ed48c1).html
https://pure.qub.ac.uk/en/publications/azimuthal-asymmetry-in-collective-electron-dynamics-in-relativistically-transparent-laserfoil-interactions(6023ecfe-3baf-4a3e-9544-f72270ed48c1).html
Autor:
Simone Mantellini, Guy Simpson, Irka Hajdas, Maurizio Tosi, Luca C. Malatesta, Sébastien Castelltort, Amriddin E. Berdimuradov, Vincenzo Picotti, Sean D. Willett
Publikováno v:
Radiocarbon
Scopus-Elsevier
Scopus-Elsevier
The oasis of Samarkand in the Middle Zeravshan Valley (modern Uzbekistan) was a major political and economic center in ancient western Central Asia. The chronology of its irrigation system was, until now, only constrained by the quality and quantity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bfee3fc78d2f5c438fe9a12bc326822
http://hdl.handle.net/11585/126303
http://hdl.handle.net/11585/126303