Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Randal C. Paniello"'
Publikováno v:
The Laryngoscope. 128:E247-E250
Objectives/hypothesis In animal studies, intramuscular vincristine injections have been shown to block reinnervation of the denervated target muscle. This application could be used selectively to influence recovery patterns following injury of recurr
Autor:
Neel K. Bhatt, Khadijeh Bijangi-Vishehsaraei, Randal C. Paniello, Hongji Zhang, Stacey L. Halum, Sarah Brookes
Publikováno v:
The Laryngoscope. 128:E241-E246
Objective Muscle progenitor cells (MPCs) can be isolated from muscle samples and grown to a critical mass in culture. They have been shown to survive and integrate when implanted into rat laryngeal muscles. In this study, the ability of MPC implants
Publikováno v:
The Laryngoscope. 127:651-655
Objectives/Hypothesis To investigate the efficacy of paclitaxel, a potent microtubule inhibitor with a more favorable therapeutic index as compared with vincristine, in preventing post-traumatic nerve regeneration of the recurrent laryngeal nerve int
Publikováno v:
The Laryngoscope. 126:2325-2329
Objectives/Hypothesis A simple, safe and effective surgical alternative for treating adductor spasmodic dysphonia (ADSD) would appeal to many patients. This study evaluates a new option, using radiofrequency-induced thermotherapy (RFITT) of the thyro
Autor:
Randal C. Paniello, Andrea M. Park
Publikováno v:
Annals of Otology, Rhinology & Laryngology. 124:484-489
Objectives: It has been shown in a canine model that a single injection of vincristine into the posterior cricoarytenoid (PCA) muscle at the time of recurrent laryngeal nerve (RLN) injury effectively blocks its reinnervation and results in improved a
Publikováno v:
The Laryngoscope. 125:E67-E72
Objectives/Hypothesis Most patients with unilateral vocal fold paralysis experience some degree of spontaneous reinnervation, which depends upon the type and severity of recurrent laryngeal nerve (RLN) injury. After partial recovery, the paretic voca
Vocal fold paralysis: Improved adductor recovery by vincristine blockade of posterior cricoarytenoid
Autor:
Randal C. Paniello
Publikováno v:
The Laryngoscope. 125:655-660
Objectives/Hypothesis A new treatment for acute unilateral vocal-fold paralysis (UVFP) was proposed in which a drug is injected into the posterior cricoarytenoid muscle (PCA) shortly after nerve injury, before the degree of natural recovery is known,
Publikováno v:
Annals of Otology, Rhinology & Laryngology. 117:382-388
Objectives: This study was performed to investigate the muscle-nerve-muscle reinnervation technique in the larynx, in which a nerve conduit implanted into an innervated muscle conducts axonal sprouting into a denervated muscle while maintaining funct
Publikováno v:
Annals of Otology, Rhinology & Laryngology. 110:532-542
This study was performed to determine whether the hypoglossal nerve (cranial nerve XII [XII]) would serve as a useful donor for laryngeal reinnervation by anastomosis to the recurrent laryngeal nerve (RLN). Twenty hemilarynges in 10 dogs were studied
Autor:
Randal C. Paniello
Publikováno v:
The Laryngoscope. 120:S61-S61
Objectives: Laryngeal transplantation may become feasible in the next several years. A functional transplant will require separate reinnervation by nerves that are activated synchronously with laryngeal adductor and abductor functions, ideally by bra