Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Wayne B. Anderson"'
Publikováno v:
Journal of Biological Chemistry. 269:4761-4766
To examine the biological properties of protein kinase C (PKC)-delta and -epsilon NIH 3T3 cells were stably transfected with metallothionein-based expression vectors that overexpressed these isoforms. In addition to their inducibility by Zn2+, the pr
Publikováno v:
Neurochemical Research. 15:515-518
Protein kinase C (PKC) activity was determined in different (membrane, nuclear and soluble) subcellular fractions prepared separately from the CA1 and CA3 subfields of Mongolian gerbils hippocampus at various time intervals following a single 5-min o
Publikováno v:
Chemical research in toxicology. 17(5)
Dichloroacetic acid (DCA) is a drinking water contaminant, a therapeutic agent, and a rodent carcinogen. Glutathione transferase zeta (GSTZ1-1) catalyzes the biotransformation of a range of alpha-haloalkanoates and the cis-trans isomerization of male
Publikováno v:
The Biochemical journal. 276
Previously it was reported that transformation of NIH 3T3 fibroblast by the Ha-ras, v-src, v-fms, and A-raf oncogenes decreased the stimulatory effects of phorbol 12-myristate 13-acetate (PMA; ‘TPA’), an activator of protein kinase C (PKC), on th
Publikováno v:
Experimental Brain Research. 84
In this report we describe changes in the intracellular redistribution of raf serine/threonine protein kinase (product of the raf proto-oncogene family) in hippocampal neurons following cerebral ischemia in Mongolian gerbils. For immunohistochemical
Publikováno v:
Endocrinology. 110:1231-1237
The present study was designed to assess the effectiveness of multiplication-stimulating activity (MSA), an insulin-like growth factor, in supporting the growth of F9 cells (an embryonal carcinoma line with properties similar to embryonic stem cells)
Publikováno v:
Biochemical and Biophysical Research Communications. 90:1159-1165
Summary A rat kidney cortex lysosomal protease [Strewler, G. J., Manganiello, V. C. and Vaughan, M. (1977) J. Biol. Chem. 253, 390–394] which activates cyclic nucleotide phosphodiesterases has been shown to potentiate adenylate cyclase activity in
Publikováno v:
Proceedings of the National Academy of Sciences. 70:3802-3805
To investigate how cell population density influences the intracellular concentration of cyclic AMP we have measured adenylate cyclase and cyclic AMP phosphodiesterase activities and cyclic AMP levels at various stages of cell density in normal rat-k
Publikováno v:
FEBS Letters. 102:329-332
Publikováno v:
Proceedings of the National Academy of Sciences. 86:6758-6762
The susceptibility of purified protein kinase C to oxidative inactivation by H2O2 was found to be increased by Ca2+ either alone at a high (5 mM) concentration or at a low (approximately 50 microM) concentration along with phosphatidylserine and diac