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pro vyhledávání: '"Herbert L. Mathews"'
Publikováno v:
Brain, behavior, and immunity. 67
It is well-established that psychological distress reduces natural killer cell immune function and that this reduction can be due to the stress-induced release of glucocorticoids. Glucocorticoids are known to alter epigenetic marks associated with im
Autor:
Herbert L. Mathews, Linda Witek Janusek, Kevin Albuquerque, Justin L. Eddy, Teresa Konley, Kelly Loster Kosik, Karen Krukowski
Publikováno v:
Brain, Behavior, and Immunity. 25:830-839
The molecular basis for psychosocial-distress mediated immune-dysregulation is not well understood. The purpose of this study was to determine whether peripheral blood mononuclear cell (PBMC) epigenetic pattern associates with this form of immune dys
Autor:
Angela R. Starkweather, Linda Witek-Janusek, Jonna Peterson, Russ P. Nockels, Herbert L. Mathews
Publikováno v:
Spine. 31:E641-E647
STUDY DESIGN This study was an exploratory repeated measures design comparing patients undergoing two magnitudes of surgery in the lumbar spine: lumbar herniated disc repair and posterior lumbar fusion. OBJECTIVE The present study evaluated and compa
Publikováno v:
Cellular immunology. 290(1)
Although glucocorticoids are well known for their capacity to suppress the immune response, glucocorticoids can also promote immune responsiveness. It was the purpose of this investigation to evaluate the molecular basis for this apparent dichotomous
Autor:
Kimberly L. Adams, Herbert L. Mathews, Thomas M. Ellis, Ninef Zaya, Walter J. Storkus, Phong T. Le
Publikováno v:
The Journal of Immunology. 166:2194-2201
T/NK progenitors are present in the thymus; however, the thymus predominantly promotes T cell development. In this study, we demonstrated that human thymic epithelial cells (TEC) inhibit NK cell development. Most ex vivo human thymocytes express CD1a
Publikováno v:
Journal of Medical Microbiology. 47:1007-1014
Interleukin-2 (IL-2)-activated lymphocytes interact directly with, and inhibit, the growth of Candida albicans hyphae. C. albicans-stimulated natural killer (NK1.1+) lymphocytes were demonstrated to secrete a soluble product capable of directly affec
Physical and psychological stressors reduce natural killer cell function. This reduction in cellular function results from stress-induced release of glucocorticoids. Glucocorticoids act upon natural killer cells to deacetylate and transrepress immune
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ae0a101be0afcbb61d60f83697ee83a
https://europepmc.org/articles/PMC3348463/
https://europepmc.org/articles/PMC3348463/
Autor:
Kelly Loster Kosik, Justin L. Eddy, Linda Witek Janusek, Herbert L. Mathews, Karen Krukowski, Teresa Konley
Publikováno v:
Brain, behavior, and immunity. 25(2)
It is well-established that psychological distress reduces natural killer cell activity (NKCA) and dysregulates cytokine balance. This may be mediated by stress-induced release of glucocorticoids, which have broad effects on the immune system, includ
Autor:
Herbert L. Mathews, David W.A. Beno
Publikováno v:
Cellular Immunology. 128:89-100
Previous reports have demonstrated natural killer cells (NK) to exert growth inhibitory effects against certain fungi, but not against Candida albicans . In this investigation, interleukin-2 (IL-2)-induced lymph node cells with phenotypic and functio
Publikováno v:
Psychoneuroendocrinology. 32(1)
The purpose of this study was to evaluate a woman's psychological and immunological response to breast biopsy before and after the procedure. Women were enrolled into the study when notified of the need for breast biopsy. Psychological and immunologi