Zobrazeno 1 - 10
of 23
pro vyhledávání: '"R. Scott Hawley"'
Autor:
Kasun Buddika, Brian R. Calvi, Michael J. Dixon, Danny E. Miller, Bernard Y. Kim, R. Scott Hawley, Lily Kahsai, Kevin R. Cook, Nicholas S. Sokol
Publikováno v:
G3: Genes|Genomes|Genetics
G3: Genes, Genomes, Genetics, Vol 10, Iss 11, Pp 4271-4285 (2020)
G3: Genes, Genomes, Genetics, Vol 10, Iss 11, Pp 4271-4285 (2020)
Balancers are rearranged chromosomes used in Drosophila melanogaster to maintain deleterious mutations in stable populations, preserve sets of linked genetic elements and construct complex experimental stocks. Here, we assess the phenotypes associate
Autor:
Anoja Perera, R. Scott Hawley, Kate Hall, Shannon Kalsow, J. J. Emerson, Mahul Chakraborty, Danny E. Miller, Edwin A. Solares
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 8, Iss 10, Pp 3143-3154 (2018)
G3: Genes|Genomes|Genetics
Solares, Edwin A; Chakraborty, Mahul; Miller, Danny E; Kalsow, Shannon; Hall, Kate; Perera, Anoja G; et al.(2018). Rapid Low-Cost Assembly of the Drosophila melanogaster Reference Genome Using Low-Coverage, Long-Read Sequencing.. G3 (Bethesda, Md.), 8(10), 3143-3154. doi: 10.1534/g3.118.200162. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/8bp73388
G3: Genes|Genomes|Genetics
Solares, Edwin A; Chakraborty, Mahul; Miller, Danny E; Kalsow, Shannon; Hall, Kate; Perera, Anoja G; et al.(2018). Rapid Low-Cost Assembly of the Drosophila melanogaster Reference Genome Using Low-Coverage, Long-Read Sequencing.. G3 (Bethesda, Md.), 8(10), 3143-3154. doi: 10.1534/g3.118.200162. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/8bp73388
Accurate and comprehensive characterization of genetic variation is essential for deciphering the genetic basis of diseases and other phenotypes. A vast amount of genetic variation stems from large-scale sequence changes arising from the duplication,
Publikováno v:
Genetics
In addition to a defined number of essential chromosomes, extra chromosomes called “B chromosomes” are present in roughly 15% of eukaryotic species. In this study, Hanlon et al. analyzed the recently discovered Drosophila melanogaster...
The
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The Molecular and Genetic Characterization of Second Chromosome Balancers in Drosophila melanogaster
Autor:
R. Scott Hawley, Angela L Miller, Vivienne Fang, Danny E. Miller, Kevin R. Cook, Elizabeth A Hemenway, Karen G. Hales
Publikováno v:
G3: Genes|Genomes|Genetics
Balancer chromosomes are multiply inverted and rearranged chromosomes used in Drosophila melanogaster for many tasks, such as maintaining mutant alleles in stock and complex stock construction. Balancers were created before molecular characterization
Autor:
Nazanin Yeganeh Kazemi, Alexandria J. Cockrell, Alexandra V. Arvanitakis, Danny E. Miller, Sue L. Jaspersen, Justin P. Blumenstiel, Clarissa B. Smith, R. Scott Hawley
Publikováno v:
Genetics
A century of genetic analysis has revealed that multiple mechanisms control the distribution of meiotic crossover events. In Drosophila melanogaster, two significant positional controls are interference and the strongly polar centromere effect. Here,
Autor:
R. Scott Hawley, Jonathan K. Trautman, Timothy J. Dahlem, David Grunwald, Cathleen M. Lake, Michelle Christian, Kelly J. Beumer, Daniel F. Voytas, Dana Carroll
Publikováno v:
G3: Genes|Genomes|Genetics
Zinc-finger nucleases have proven to be successful as reagents for targeted genome manipulation in Drosophila melanogaster and many other organisms. Their utility has been limited, however, by the significant failure rate of new designs, reflecting t
Autor:
R. Scott Hawley, Jeff Sekelsky, Stephanie P. Bellendir, Julie Korda Holsclaw, Cathleen M. Lake
Publikováno v:
G3: Genes|Genomes|Genetics
The recognition of DNA double-strand breaks (DSBs) using a phospho-specific antibody to the histone 2A variant has become the gold standard assay for DNA damage detection. Here we report on the development of the first monoclonal antibody to the phos
Autor:
R. Scott Hawley
Publikováno v:
Genetics. 189:405-409
Four different SYP proteins (SYP-1, SYP-2, SYP-3, and SYP-4) have been proposed to form the central region of the synaptonemal complex (SC) thereby bridging the axes of paired meiotic chromosomes in Caenorhabditis elegans. Their interdependent locali
Publikováno v:
Genetics. 186:505-513
Many advances in the understanding of meiosis have been made by measuring how often errors in chromosome segregation occur. This process of nondisjunction can be studied by counting experimental progeny, but direct measurement of nondisjunction rates
Autor:
Jennifer K. Jeffress, Lorinda K. Anderson, Suzanne M. Royer, Justin P. Blumenstiel, Scott L. Page, Elizabeth D. Belden, R. Scott Hawley
Publikováno v:
Genetics. 177:2445-2456
In Drosophila melanogaster oocytes, the C(3)G protein comprises the transverse filaments (TFs) of the synaptonemal complex (SC). Like other TF proteins, such as Zip1p in yeast and SCP1 in mammals, C(3)G is composed of a central coiled-coil-rich domai