Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Vishwanath R. Lingappa"'
Publikováno v:
Nature. 417:87-91
Most mitochondrial proteins are synthesized on cytoplasmic ribosomes and imported into mitochondria. The imported proteins are directed to one of four submitochondrial compartments--the outer mitochondrial membrane, the inner mitochondrial membrane,
Publikováno v:
Journal of Virology. 64:1414-1419
The coding region for the hepatitis B virus surface antigens contains three in-phase ATG codons which direct the synthesis of three related polypeptides. The 24-kilodalton major surface (or S) glycoprotein is initiated at the most distal ATG and is a
Autor:
Vishwanath R. Lingappa, Carolyn M. Ott
Publikováno v:
Biochemistry. 43(38)
Biosynthesis of the prion protein at the endoplasmic reticulum generates multiple topological forms. The topology of an individual chain is determined first by the localization of the N terminus and then by potential integration of the transmembrane
Publikováno v:
Endocrine research. 28(4)
The steroidogenic acute regulatory protein (StAR) facilitates the movement of cholesterol into mitochondria to initiate steroidogenesis, but its site of action on the mitochondria has been uncertain. One model states that StAR has a fairly rigid stru
Autor:
Vishwanath R. Lingappa
Publikováno v:
Cell biophysics. 19(1-3)
I have described recent work that supports several conclusions that might not have been previously expected: first, that stop transfer, like the initiation of translocation, is receptor-mediated; second, that at least some of the topology-determining
Publikováno v:
Science. 232:348-352
The segregation of secretory proteins into the cisternae of the endoplasmic reticulum (ER) is normally tightly coupled to their synthesis. This feature distinguishes their biogenesis from that of proteins targeted to many other organelles. In the exa
Publikováno v:
Proceedings of the National Academy of Sciences. 76:1795-1799
The ability of microsomal membranes to translocate nascent presecretory proteins across their lipid bilayer into the intravesicular space was investigated by using trypsin as a proteolytic probe. We found that under defined conditions trypsin is able
Publikováno v:
The Journal of Cell Biology
Hepatitis B surface antigen (HBsAg), the major coat protein of hepatitis B virus, is also independently secreted from infected cells as a lipoprotein particle. Secretion proceeds without signal sequence removal or cleavage of other segments of the po
Autor:
Jean-Philippe Rosa, Marc A. Shuman, Yuet Wai Kan, Paul F. Bray, Vishwanath R. Lingappa, Rodger P. McEver
Congenital absence of platelet glycoproteins IIb and IIIa (GPIIb and GPIIIa) results in a severe bleeding disorder characterized by defective platelet aggregation and failure of fibrinogen to bind to platelets. GPIIb is a two-chain protein containing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c66e76475f70f7ae39be347481dae5c
https://europepmc.org/articles/PMC323100/
https://europepmc.org/articles/PMC323100/