Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Shahin Jamal"'
Autor:
Tatiana Nevskaya, Shahin Jamal, Ines Colmegna, Aurore Fifi-Mah, Nancy Maltez, Karam Al Jumaily, Annaliese Tisseverasinghe, Carrie Ye, Sabrina Hoa, Megan E. Himmel, Janet Roberts, Marie Hudson, Daniel Ennis, Janet E. Pope, Robert Rottapel, Christina Ly, Linda Laaouad, Alexandra Saltman
Publikováno v:
Cancer Immunology, Immunotherapy. 70:2197-2207
Limited data are available on the safety and efficacy of immune checkpoint inhibitors (ICI) in patients with preexisting autoimmune diseases (PAD). Retrospective study of patients with PAD referred for rheumatologic evaluation prior to starting or du
Publikováno v:
Current Treatment Options in Rheumatology. 5:272-289
Immune checkpoint inhibitors (ICI) are now the cornerstone of treatment for metastatic melanoma and are increasingly used in many other advanced stage malignancies. Immune checkpoint inhibitors enhance the endogenous anti-tumor response by inhibiting
Autor:
Shahin Jamal, Jessica Widdifield, Justin Shamis, Claire E.H. Barber, Alfred Cividino, Dharini Mahendira, B. Cord Lethebe, Michelle Batthish
Publikováno v:
Canadian Medical Education Journal, Vol 12, Iss 2 (2020)
Background: There are regional disparities in the distribution of Canadian rheumatologists. The objective of this study was to identify factors impacting rheumatology residents’ postgraduate practice decisions to inform Canadian Rheumatology Associ
Autor:
Shahin Jamal, Edward C. Keystone, John Woolcott, Lara Fallon, Janet E. Pope, Douglass Chapman, Lisy Wang, Boulos Haraoui, Irina Lazariciu
Publikováno v:
Acr Open Rheumatology
ACR Open Rheumatology, Vol 1, Iss 2, Pp 73-82 (2019)
ACR Open Rheumatology, Vol 1, Iss 2, Pp 73-82 (2019)
Objective Tofacitinib is an oral Janus kinase inhibitor for the treatment of rheumatoid arthritis (RA). This post hoc analysis evaluated tofacitinib persistence in patients with RA in long‐term extension (LTE) studies up to 9.5 years. Methods Data
Autor:
A. Hillary Steinhart, Boulos Haraoui, Melinda Gooderham, John Marshall, Donald C. Vinh, Janet E. Pope, Shahin Jamal, Kim A. Papp, Robert Bissonnette, Alain Bitton, Brian Bressler, John Wade, Vincent T. Ho, Deepali Kumar
Publikováno v:
Journal of the Canadian Association of Gastroenterology
The use of immunosuppressive therapies for immune-mediated disease (IMD) is associated with an elevated risk of infections and related comorbidities. While many infectious diseases can generally be prevented by vaccines, immunization rates in this sp
Autor:
Tarang Manchanda, Diana Fung, Shahin Jamal, Majed Khraishi, Vandana Ahluwalia, Boulos Haraoui
Publikováno v:
Rheumatology and Therapy
Rheumatology and Therapy, Vol 5, Iss 2, Pp 551-565 (2018)
Rheumatology and Therapy, Vol 5, Iss 2, Pp 551-565 (2018)
Introduction This study was conducted to observe patterns of use of the interleukin-6 receptor-alpha inhibitor tocilizumab in routine clinical practice in patients with rheumatoid arthritis (RA). Methods This was a 12-month noninterventional, observa
Autor:
Sabrina Hoa, Alexandra Saltman, Shahin Jamal, Carrie Ye, Janet E. Pope, Annaliese Tisseverasinghe, Megan E. Himmel, Aurore Fifi-Mah, Janet Roberts, Robert Rottapel, Marie Hudson, Daniel Ennis, Nancy Maltez
Publikováno v:
Autoimmunity reviews. 19(8)
Objective Although immune checkpoint inhibitors (ICI) have revolutionized cancer therapy, their use is associated with immune toxicities referred to as immune-related adverse events (irAE). Here we describe the clinical presentation and management of
Autor:
Susan M. Goodman, Shahin Jamal, Carol A. Hitchon, Kathleen M. Andersen, Diane Tin, Catch Investigators, Vivian P. Bykerk, Susan J. Bartlett, Boulos Haraoui, Carter Thorne, Orit Schieir, Elizabeth Schulman, Janet E. Pope, Edward C. Keystone, Gilles Boire
Publikováno v:
Arthritis Care & Research. 70:1185-1191
OBJECTIVE Obesity is implicated in rheumatoid arthritis (RA) development, severity, outcomes, and treatment response. We estimated the independent effects of overweight and obesity on ability to achieve sustained remission (sREM) in the 3 years follo
Publikováno v:
Abstracts Accepted for Publication.
Background Immune checkpoint inhibitors (ICI) have revolutionized the treatment of cancer. However, enhanced immune activation from ICI has been associated with immune-related adverse events (irAE), including autoimmune rheumatologic diseases such as
Autor:
Kim A. Papp, Deepali Kumar, Donald C. Vinh, Melinda Gooderham, Shahin Jamal, John Marshall, Brian Bressler, Janet E. Pope, Alain Bitton, A. Hillary Steinhart, Boulos Haraoui, John Wade, Vincent T. Ho, Robert Bissonnette
Publikováno v:
The Journal of rheumatology. 46(7)
The use of immunosuppressive therapies for immune-mediated disease is associated with an elevated risk of infections and related comorbidities. While many infectious diseases can generally be prevented by vaccines, immunization rates in this specific