Zobrazeno 1 - 10
of 779
pro vyhledávání: '"Richard, O."'
Publikováno v:
Therapeutic Drug Monitoring. 43:736-746
BACKGROUND Therapeutic drug monitoring is recommended to guide tacrolimus dosing because of its narrow therapeutic window and considerable pharmacokinetic variability. This study assessed tacrolimus dosing and monitoring practices in heart transplant
Autor:
Sophie L. Stocker, Stefanie Hennig, Ranita Kirubakaran, Richard O. Day, Jane E. Carland, Ben Maslen
Publikováno v:
British Journal of Clinical Pharmacology. 88:1751-1772
BACKGROUND AND AIM Identification of the most appropriate population pharmacokinetic model-based Bayesian estimation is required prior to its implementation in routine clinical practice to inform tacrolimus dosing decisions. This study aimed to deter
Targeting neurotrophic factors for low back pain and sciatica: a systematic review and meta-analysis
Autor:
Richard O. Day, Michael A. Wewege, Matthew D. Jones, James H. McAuley, Sylvia M. Gustin, Aidan G Cashin, Michael C Ferraro, Hayley B. Leake, Rodrigo R N Rizzo, Andrew J. McLachlan, Edel O'Hagan
Publikováno v:
Rheumatology. 61:2243-2254
Objectives This meta-analysis aims to investigate the efficacy and safety of medicines that target neurotrophic factors for low back pain (LBP) or sciatica. Methods We searched published and trial registry reports of randomized controlled trials eval
Autor:
Richard O. White, Floyd B. Willis, La Princess C. Brewer, Christopher T. Pullins, Sarah M. Jenkins, Maarya Pasha, Sumedha G. Penheiter, Pernessa C. Seele, Monica Albertie
Publikováno v:
Journal of General Internal Medicine
Background African Americans (AAs) and other racial/ethnic minority groups continue to be underrepresented in medical research and clinical trials. Failure to create more racially diverse research cohorts can exacerbate existing health disparities am
Autor:
H. Ahedi, Christopher G. Maher, Vicki Langendyk, Richard O. Day, Steven J. Kamper, Giovanni E Ferreira, Christine Lin, Andrew J. McLachlan, Alissa Dmitritchenko, Christina Abdel Shaheed, Bruno T Saragiotto, Jane Latimer, Fiona Stanaway, Hanan McLachlan
Publikováno v:
Medical Journal of Australia. 214:324-331
Objective To evaluate the efficacy and safety of paracetamol as an analgesic medication in a range of painful conditions. Study design Systematic review of systematic reviews of the analgesic effects of paracetamol in randomised, placebo-controlled t
Publikováno v:
Current Opinion in Nephrology & Hypertension. 30:245-251
Purpose of review There is controversy regarding the impact of hyperuricemia on the progression of chronic kidney disease (CKD), and gout remains sub optimally managed in this population. We discuss the prescribing of drugs for the treatment of gout
Autor:
Kim C Donaghue, Bruce R. King, D Jane Holmes-Walker, Craig Jefferies, Meng Tuck Mok, P Shane Hamblin, Melissa Chee, Timothy W. Jones, Helen L. Barrett, Elizabeth E Davis, Arul Earnest, Benjamin J Wheeler, Richard O. Sinnott, Stephanie R. Johnson, Anthony Zimmermann, Glenn M. Ward, Fergus J. Cameron, P. Gerry Fegan, Jenny Couper, Maria E. Craig, Philip Bergman, Peter G. Colman
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 106:133-142
Context Cardiovascular disease occurs prematurely in type 1 diabetes. The additional risk of overweight is not well characterized. Objective The primary aim was to measure the impact of body mass index (BMI) in youth with type 1 diabetes on cardiovas
Publikováno v:
Drug Safety
Sodium-glucose cotransporter 2 (SGLT2) inhibitors are a major advance in the fields of diabetology, nephrology, and cardiology. The cardiovascular and renal benefits of SGLT2 inhibitors are likely largely independent of their glycaemic effects, and t
Autor:
Felix I.L. Clanchy, Ali S. M. Jawad, Rizgar A. Mageed, Jonas Bystrom, Richard O. Williams, Pamela Mangat, Mohammed M. Al-Bogami, Taher E. Taher
Publikováno v:
Rheumatology. 60:947-957
Objectives About half of RA patients treated with TNFα inhibitors either do not respond or lose their initial therapeutic response over time. The clinical response is measured by reduction in DAS28, which primarily reflects inflammation. However, ot
Autor:
Neil Boudville, Suetonia C. Palmer, Fiona G. Brown, Giles Walters, Richard O. Day, Graham R D Jones, Randall J. Faull, Robert J. Walker, Bettina Douglas, Elaine M. Pascoe, Philip Clarke, Vlado Perkovic, Anushree Tiku, Carmel M. Hawley, Donna Reidlinger, David W. Johnson, Ckd-Fix Study Investigators, Janak de Zoysa, David Harris, Alan Cass, John Kanellis, Sunil V. Badve, Laura Robison, Gopala K. Rangan, Nicola Dalbeth
Publikováno v:
New England Journal of Medicine. 382:2504-2513
Background Elevated serum urate levels are associated with progression of chronic kidney disease. Whether urate-lowering treatment with allopurinol can attenuate the decline of the estimat...