Zobrazeno 1 - 10
of 71
pro vyhledávání: '"Olle Söder"'
Autor:
Halima Albalushi, Magdalena Kurek, Leif Karlsson, Luise Landreh, Kristín Rós Kjartansdóttir, Olle Söder, Outi Hovatta, Jan-Bernd Stukenborg
Publikováno v:
Stem Cells International, Vol 2018 (2018)
Human embryonic stem (hES) cells represent an important tool to study early cell development. The previously described use of human recombinant laminin (LN) 521 represented a step forward in generating clinically safe culture conditions. To test the
Externí odkaz:
https://doaj.org/article/6452a9331bd54054b0e10cdbfab01411
Autor:
Beate Jessnitzer, Isabel Viola Wagner, Olle Söder, Michael Stumvoll, Susan Kralisch, Ulrike Lossner, Nora Klöting, Lisa Eifler, Annett Hoffmann, Mathias Fasshauer, Lena Sahlin, Thomas Ebert
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1864:3292-3297
Female reproductive dysfunction occurs in patients with pathological loss of adipose tissue, i.e. lipodystrophy (LD). However, mechanisms remain largely unclear and treatment effects of adipocyte-derived leptin have not been assessed in LD animals.In
Autor:
Nora Klöting, Iuliia Savchuk, Olle Söder, Lena Sahlin, Isabel Viola Wagner, Konstantin Svechnikov
Publikováno v:
Obesity. 26:1161-1167
OBJECTIVE Obesity in females is often associated with metabolic complications and hyperandrogenism, but the sources of androgens are not completely understood. Therefore, this study investigated whether adipose tissue could be a source of androgens p
Autor:
Sheyla Cisneros Montalvo, Jan-Bernd Stukenborg, Zeliha Sahin, Halima Albalushi, Olle Söder, Mirja Nurmio, Jorma Toppari, Mi Hou, Niels Geijsen, Ahmed Reda
Publikováno v:
Annals of Biomedical Engineering, 45(7), 1783-1794. Springer Netherlands
Annals of Biomedical Engineering
Annals of Biomedical Engineering
Finding robust culture conditions for in vitro maturation (IVM) of male germ cells is still a challenge. Recently, a testis organ culture method, using Knockout Serum Replacement (KSR), was suggested as a promising approach. However, the efficiency o
Autor:
Antonella Puglianiello, Daniela Germani, Ahmed Reda, Valentina Pampanini, Jan-Bernd Stukenborg, Stefano Cianfarani, Iuliia Savchuk, Kristín Rós Kjartansdóttir, Olle Söder
Publikováno v:
The Journal of Endocrinology
Prenatal events such as intrauterine growth restriction can affect gonadal development of the offspring and have an impact on reproductive health. To investigate the effects of intrauterine growth restriction induced by uterine artery ligation on the
Autor:
Mathilde Gersel Wegmann, Guftar Shaikh, Olle Söder, Sten A. Ivarsson, Edna Roche, Jeremy Kirk, Anders Juul, David B. Dunger, Hilary Hoey, Rikke Beck Jensen, Ajay Thankamony, Jan Frystyk
Publikováno v:
Wegmann, M G, Jensen, R B, Thankamony, A, Frystyk, J, Roche, E, Hoey, H, Kirk, J, Shaikh, G, Ivarsson, S-A, Söder, O, Dunger, D B & Juul, A 2020, ' Increases in bioactive IGF do not parallel increases in total IGF-I during growth hormone treatment of children born SGA ', The Journal of clinical endocrinology and metabolism, vol. 105, no. 4, dgz118, pp. E1291-E1298 . https://doi.org/10.1210/clinem/dgz118
Wegmann, M G, Jensen, R B, Thankamony, A, Frystyk, J, Roche, E, Hoey, H, Kirk, J, Shaikh, G, Ivarsson, S-A, Söder, O, Dunger, D B & Juul, A 2020, ' Increases in bioactive IGF do not parallel increases in total IGF-I during growth hormone treatment of children born SGA ', The Journal of clinical endocrinology and metabolism, vol. 105, no. 4, dgz118 . https://doi.org/10.1210/clinem/dgz118
Wegmann, M G, Jensen, R B, Thankamony, A, Frystyk, J, Roche, E, Hoey, H, Kirk, J, Shaikh, G, Ivarsson, S-A, Söder, O, Dunger, D B & Juul, A 2020, ' Increases in Bioactive IGF do not Parallel Increases in Total IGF-I During Growth Hormone Treatment of Children Born SGA ', Journal of Clinical Endocrinology and Metabolism, vol. 105, no. 4, pp. e1291–e1298 . https://doi.org/10.1210/clinem/dgz118
Wegmann, M G, Jensen, R B, Thankamony, A, Frystyk, J, Roche, E, Hoey, H, Kirk, J, Shaikh, G, Ivarsson, S-A, Söder, O, Dunger, D B & Juul, A 2020, ' Increases in bioactive IGF do not parallel increases in total IGF-I during growth hormone treatment of children born SGA ', The Journal of clinical endocrinology and metabolism, vol. 105, no. 4, dgz118 . https://doi.org/10.1210/clinem/dgz118
Wegmann, M G, Jensen, R B, Thankamony, A, Frystyk, J, Roche, E, Hoey, H, Kirk, J, Shaikh, G, Ivarsson, S-A, Söder, O, Dunger, D B & Juul, A 2020, ' Increases in Bioactive IGF do not Parallel Increases in Total IGF-I During Growth Hormone Treatment of Children Born SGA ', Journal of Clinical Endocrinology and Metabolism, vol. 105, no. 4, pp. e1291–e1298 . https://doi.org/10.1210/clinem/dgz118
Background Some children born small for gestational age (SGA) experience supra-physiological insulin-like growth factor-I (IGF-I) concentrations during GH treatment. However, measurements of total IGF-I concentrations may not reflect the bioactive fr
Autor:
Eva Serlachius, Kristiina Tammimies, Paul Lichtenstein, Olle Söder, Louise Frisén, Sven Bölte, Catarina Almqvist, Vide Ohlsson Gotby, Henrik Larsson
Publikováno v:
Journal of neuroendocrinologyREFERENCES. 31(11)
Hypogonadotrophic hypogonadism (HH) is a rare disorder that manifests absent puberty and infertility. Genetic syndromes with hypogonadism, such as Klinefelter syndrome, are associated with an increased risk of neurodevelopmental disorders (NDDs). How
Autor:
Elisabet Åkesson, Lena Sahlin, Outi Hovatta, Jan-Bernd Stukenborg, Kristín Rós Kjartansdóttir, Olle Söder, Halima Albalushi, Magdalena Kurek, Rika Lindh, Emilia Rotstein
Publikováno v:
Endocrinology. 160(1)
In the past, explant tissue-culture methodologies have been used to grow gonads and study their development. Results from in vitro cultures of human gonads showed limited progress toward gonadal cell differentiation and were focused mainly on germ-ce
Autor:
Olle Söder, Ulrike Lossner, Gloria-Maria Manjowk, Susan Kralisch, Matthias Blüher, Mathias Fasshauer, Isabel Viola Wagner, Michael Stumvoll, Beate Jessnitzer, Thomas Ebert, Jan-Bernd Stukenborg, Annett Hoffmann, Konstantin Svechnikov, Nora Klöting
Publikováno v:
Endocrinology. 157:2461-2468
Obesity has recently been linked with reduced fertility, and the mechanisms underpinning this effect are currently unknown. The adipokine leptin is dysregulated in obesity and affects reproductive tracts; therefore, we investigated the dose-dependent
Autor:
Edna Roche, David B. Dunger, Anders Juul, Malcolm Donaldson, Jeremy Kirk, Hilary Hoey, Ken K. Ong, Olle Söder, Rikke Beck Jensen, Sten A. Ivarsson, Ajay Thankamony, Felix R. Day, Susan M. O'Connell
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 101:131-142
BACKGROUND: Genetic susceptibility to insulin resistance is associated with lower adiposity in adults. Insulin resistance, and therefore adiposity, may alter sensitivity to GH. We aimed to determine the relationship between adiposity, genetic suscept