Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Melanie Boerries"'
Autor:
Michal Kulinski, Annette Schmitt-Graeff, Tony A. Mueller, Christian Peschel, Melanie Boerries, Christine Dierks, Teresa Poggio, Irith Baumann, Justus Duyster, Milena Pantic, Michael L. Cleary, Nina Cabezas-Wallscheid, Khalid Shoumariyeh, Alina Mueller-Rudorf, Bernhard Kuster, Marie Follo, Hiroyuki Kawaguchi, Simone Lemeer, Miriam Erlacher, Detlev Schindler, Martina Rudelius, Anna Lena Illert, Tamina Rückert, Cathrin Klingeberg, Robert A.J. Oostendorp, Rouzanna Istvanffy, Jesus Duque-Afonso, Stefanie Kreutmair, Marcin W. Wlodarski, Charlotte M. Niemeyer, Dietmar Pfeifer, Geoffroy Andrieux, Robert Zeiser, Melissa Zwick
Publikováno v:
The Journal of Clinical Investigation
J Clin Invest
J Clin Invest
Inherited bone marrow failure syndromes (IBMFSs) are a heterogeneous group of disorders characterized by defective hematopoiesis, impaired stem cell function, and cancer susceptibility. Diagnosis of IBMFS presents a major challenge due to the large v
Autor:
Nicola Wanner, Geoffroy Andrieux, Pau Badia-i-Mompel, Carolin Edler, Susanne Pfefferle, Maja T. Lindenmeyer, Christian Schmidt-Lauber, Jan Czogalla, Milagros N. Wong, Yusuke Okabayashi, Fabian Braun, Marc Lütgehetmann, Elisabeth Meister, Shun Lu, Maria L. M. Noriega, Thomas Günther, Adam Grundhoff, Nicole Fischer, Hanna Bräuninger, Diana Lindner, Dirk Westermann, Fabian Haas, Kevin Roedl, Stefan Kluge, Marylyn M. Addo, Samuel Huber, Ansgar W. Lohse, Jochen Reiser, Benjamin Ondruschka, Jan P. Sperhake, Julio Saez-Rodriguez, Melanie Boerries, Salim S. Hayek, Martin Aepfelbacher, Pietro Scaturro, Victor G. Puelles, Tobias B. Huber
Publikováno v:
Nature metabolism. 4(3)
Extrapulmonary manifestations of COVID-19 have gained attention due to their links to clinical outcomes and their potential long-term sequelae1. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) displays tropism towards several organs, inc
Autor:
Anna Lena Illert, Nikolas von Bubnoff, Rouven Hoefflin, Michel Eisenblaetter, Philipp Poxleitner, Patrick Metzger, Nico Buettner, Florian Scherer, Anna-Lena Geißler, Alexander Keller, Melanie Boerries, Alexandra Kutilina, Ralph Fritsch, Christine Dierks, Jesus Duque-Afonso, Adriana Lazarou, Isabell Xiang Ge, Justus Duyster, Steffen Heeg, Frank Meiss, Andreas Tzschach, Anna Verena Frey, Cornelius Miething, Gian Kayser, Simone Hettmer, Martin Werner, Leman Mehmed, Heiko Becker, Justyna Rawluk, Julius Wehrle, Dieter Henrik Heiland, Khalid Shoumariyeh, Markus Grabbert, Tilman Brummer, Juri Ruf, Thalia Erbes, Christoph Peters, Konrad Aumann, Kai Berner, Maria Elena Hess, Meike Reiser, Martin Boeker, Anita Kleiber, Silke Lassmann, Henning Schäfer
Publikováno v:
Cancers
Volume 13
Issue 5
Cancers, Vol 13, Iss 1151, p 1151 (2021)
Volume 13
Issue 5
Cancers, Vol 13, Iss 1151, p 1151 (2021)
Simple Summary Access to molecular cancer treatments outside of clinical trials is limited and the benefit of molecular-guided, individualized patient care in patients with cancer progression after standard treatment is unclear. We here present the f
Autor:
Melanie Boerries, Dilara Akhoundova, Rhena F. U. Klar, Ralph Fritsch, Nikolas von Bubnoff, Saskia Hussung, Ulrike Philipp, Julian Hipp, Marie Follo, Justus Duyster, Florian Scherer, Uwe A. Wittel
Publikováno v:
BMC Cancer, Vol 21, Iss 1, Pp 1-10 (2021)
BMC Cancer
BMC Cancer
Background Novel biomarkers and molecular monitoring tools hold potential to improve outcome for patients following resection of pancreatic ductal adenocarcinoma (PDAC). We hypothesized that the combined longitudinal analysis of mutated cell-free pla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33ca7ff86ed7bcbef9267c23e2331c75
https://doi.org/10.5167/uzh-198678
https://doi.org/10.5167/uzh-198678
Autor:
Stefan Fröhling, Albrecht Stenzinger, Ivo Buchhalter, Peter Hohenberger, Sebastian Bauer, Ulrich Keilholz, Andreas Mock, Daniel B. Lipka, Benedikt Brors, Michael Allgäuer, Andreas Rump, Stephan Wolf, Melanie Boerries, Klaus Schulze-Osthoff, Gunnar Folprecht, Katrin Pfütze, Christof von Kalle, Christian Brandts, Michael Bitzer, Laura Gieldon, Arne Jahn, Peter Schirmacher, Olaf Neumann, Matthias Kroiss, Barbara Klink, Daniela Richter, Sebastian Uhrig, Peter Horak, Ulrike Winter, Nikolas von Bubnoff, Barbara Hutter, Walter E. Aulitzky, Wilko Weichert, Jennifer Hüllein, Philipp J. Jost, Veronica Teleanu, Thomas Kindler, Leo Ruhnke, Martina Fröhlich, Christoph E. Heilig, Katja Beck, Karsten Spiekermann, Volker Endris, Evelin Schröck, Frederick Klauschen, Dorothea Hanf, Simon Kreutzfeldt, Daniel Hübschmann, Jens T. Siveke, Bettina Meißburger, Lino Möhrmann, Richard F. Schlenk, Andreas Laßmann, Anna Lena Illert, Roland Penzel, Christina Geörg, Christoph Heining, Marinela Augustin, Hanno Glimm
The clinical relevance of comprehensive molecular analysis in rare cancers is not established. We analyzed the molecular profiles and clinical outcomes of 1,310 patients (rare cancers, 75.5%) enrolled in a prospective observational study by the Germa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15121a6ea455b994d9a46eb2bbde7d0f
https://www.ncbi.nlm.nih.gov/pubmed/34112699
https://www.ncbi.nlm.nih.gov/pubmed/34112699
Autor:
Ingmar Sören Meyer, Xue Li, David Voehringer, Norbert Frey, Hugo A. Katus, Christina Mertens, Kory J. Lavine, Julia K. Meier, Severin Dicks, Moritz P. Kornadt, Melanie Boerries, Florian Leuschner, Daniel Radtke, Florian Sicklinger, Y. Zhang, Gabriele Schramm, Tobias Terzer, Tim Christian Kuhn, Jyoti Patel
Publikováno v:
J Clin Invest
The inflammatory response after myocardial infarction (MI) is a precisely regulated process that greatly affects subsequent remodeling. Here, we show that basophil granulocytes infiltrated infarcted murine hearts, with a peak occurring between days 3
Autor:
Brigitte Schlegelberger, Melanie Boerries, Ulf Tedgård, Brigitte Strahm, Gerhard Ehninger, Miriam Erlacher, John C. Achermann, Matthias Voss, Hauke Busch, Jochen Hochrein, Irith Baumann, Victor B Pastor, Lennart Nilsson, Marena R. Niewisch, Yenan T. Bryceson, Dirk Lebrecht, Jessica Boklan, Georg C. Schwabe, Ebru Tugrul Saribeyoglu, Charlotte M. Niemeyer, Henrik Hasle, Sushree Sangita Sahoo, Akiko Shimamura, Marcin W. Wlodarski
Publikováno v:
Haematologica
Pastor, V B, Sahoo, S, Boklan, J, Schwabe, G C, Saribeyoglu, E, Strahm, B, Lebrecht, D, Voss, M, Bryceson, Y T, Erlacher, M, Ehninger, G, Niewisch, M, Schlegelberger, B, Baumann, I, Achermann, J C, Shimamura, A, Hochrein, J, Tedgård, U, Nilsson, L, Hasle, H, Boerries, M, Busch, H, Niemeyer, C M & Wlodarski, M W 2018, ' Constitutional SAMD9L mutations cause familial myelodysplastic syndrome and transient monosomy 7 ', Haematologica, vol. 103, no. 3, pp. 427-437 . https://doi.org/10.3324/haematol.2017.180778
Pastor, V B, Sahoo, S, Boklan, J, Schwabe, G C, Saribeyoglu, E, Strahm, B, Lebrecht, D, Voss, M, Bryceson, Y T, Erlacher, M, Ehninger, G, Niewisch, M, Schlegelberger, B, Baumann, I, Achermann, J C, Shimamura, A, Hochrein, J, Tedgård, U, Nilsson, L, Hasle, H, Boerries, M, Busch, H, Niemeyer, C M & Wlodarski, M W 2018, ' Constitutional SAMD9L mutations cause familial myelodysplastic syndrome and transient monosomy 7 ', Haematologica, vol. 103, no. 3, pp. 427-437 . https://doi.org/10.3324/haematol.2017.180778
Familial myelodysplastic syndromes arise from haploinsufficiency of genes involved in hematopoiesis and are primarily associated with early-onset disease. Here we describe a familial syndrome in seven patients from four unrelated pedigrees presenting
Autor:
Anita Allen, Marie Follo, Sylvia Urban, Roland Schüle, Jochen Maurer, Stella S. Stepputtis, Melanie Boerries, Jeffrey A. Stafford, Dominica Willmann, Peter Bronsert, Fides Zenk, Toufike Kanouni, Juliane Strietz, Michael Brennan Wallace, Nicola Iovino, Jiangchun Xu, Eric Metzger, Amelie Proske, Bogdan-Tiberius Preca, Elmar Stickeler
Publikováno v:
Cancer research : an official organ of the American Association for Cancer Research
Traditional treatments for breast cancer fail to address therapy-resistant cancer stem–like cells that have been characterized by changes in epigenetic regulators such as the lysine demethylase KDM4. Here, we describe an orally available, selective
Autor:
Melanie Boerries, Hermann Brenner, Dominique Scherer, Stephanie Skender, Petra Schrotz-King, Alexis Ulrich, Peter Schirmacher, Martin F. Schneider, Lin Zielske, Nina Habermann, Timothy M. Barrow, Clare Abbenhardt-Martin, Hagen Klett, Jürgen Böhm, Cornelia M. Ulrich, Biljana Gigic, Karin B. Michels, Esther Herpel, Reka Toth, Hauke Busch
Publikováno v:
The Journal of Pathology. 243:366-375
Smoking tobacco is a known risk factor for the development of colorectal cancer, and for mortality associated with the disease. Smoking has been reported to be associated with changes in DNA methylation in blood and in lung tumour tissues, although t
Autor:
Melanie Boerries, Chiara Pazzagli, Yannick Gache, Philipp R. Esser, Cristina Has, Hauke Busch, Yinghong He, Leena Bruckner-Tuderman, Dimitra Kiritsi
Publikováno v:
Journal of Investigative Dermatology. 137:1387-1391