Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Matthew R. Sarkisian"'
Autor:
Ashton Sequeira, Ronald J. Mandel, Ashok V. Kumar, Matthew R. Sarkisian, Gileno F. Filho, Thomas C. Foster, Susan L. Semple-Rowland, Sarah M. Guadiana, Alexander K. Parker, Gerry Shaw
Publikováno v:
Frontiers in Aging Neuroscience
Frontiers in Aging Neuroscience, Vol 8 (2016)
Frontiers in Aging Neuroscience, Vol 8 (2016)
The primary cilia of forebrain neurons assemble around birth and become enriched with neuromodulatory receptors. Our understanding of the permanence of these structures and their associated signaling pathways in the aging brain is poor, but they are
Autor:
Zhao Liu, John C. Neill, Jan Krzysztof Blusztajn, Gregory L. Holmes, Carl E. Stafstrom, Jennifer M. Cermak, Yili Yang, Matthew R. Sarkisian
Publikováno v:
Epilepsy Research. 48:3-13
Prenatal choline supplementation can protect rats against cognitive deficits induced by status epilepticus induced by the cholinergic agent pilocarpine [J. Neurosci. 20 (2000) 1]. In the present day, we have extended this novel finding by investigati
Autor:
Matthew R. Sarkisian, Zhao Liu, Gregory L. Holmes, Lionel Carmant, Yili Yang, Carl E. Stafstrom
Publikováno v:
Brain and Development. 21:318-325
Whether febrile seizures lead to hippocampal necrosis is a question of paramount clinical importance. This study attempted to simulate a complex febrile seizure, compared with hyperthermia (HYP) alone and prolonged seizure alone (produced by continuo
Publikováno v:
Epilepsia. 40:394-400
Summary: Purpose: Disorders in normal central nervous system (CNS) development are often associated with epilepsy. This report characterizes seizures in a novel genetic model of developmental epilepsy, the Flathead (FH) rat. Methods: Animals (n = 76)
Publikováno v:
Journal of Comparative Neurology
Journal of Comparative Neurology, Wiley, 1999, 404 (4), pp.537-53
Journal of Comparative Neurology, Wiley, 1999, 404 (4), pp.537-53
International audience; In some children, epilepsy is a catastrophic condition, leading to significant intellectual and behavioral impairment, but little is known about the consequences of recurrent seizures during development. In the present study,
Autor:
Matthew R. Sarkisian, George Ugartemendia, Lan Hoang-Minh, Dorit Siebzehnrubl, Benjamin Griffith, Susan L. Semple-Rowland, Brent A. Reynolds, Hunter S. Futch, Loic P. Deleyrolle, Joshua J. Breunig
Publikováno v:
Cancer Research. 75:1542-1542
Adults diagnosed with glioblastoma multiforme (GBM) typically have a median survival less than 15 months. GBM patient biopsies and derived cell lines contain subsets of cells extending primary cilia, microtubular antennae that mediate signaling event
Autor:
Yili Yang, Matthew R. Sarkisian, Pushpa Tandon, Zhao Liu, Gregory L. Holmes, Carl E. Stafstrom
Publikováno v:
Brain research. Developmental brain research. 107(2)
Prolonged seizures in the adult brain causes neuronal loss in the hippocampus and aberrant growth (sprouting) of granule cell axons (mossy fibers) in the supragranular zone of the fascia dentata and stratum infrapyramidale of CA3. There is considerab
Autor:
Carl E. Stafstrom, Ariyuki Hori, Gregory L. Holmes, Matthew R. Sarkisian, Pushpa Tandon, Yili Yang, Zhao Liu
Publikováno v:
Neuroreport. 8(8)
A glutamate biosensor was used to measure extracellular glutamate concentrations in the hippocampus of mature and immature animals. Significant elevations of extracellular glutamate were observed following seizures induced by either kainic acid or pi
Autor:
Jennifer M. Cermak, Gregory L. Holmes, John C. Neill, Carl E. Stafstrom, Matthew R. Sarkisian, Pushpa Tandon, Yili Yang, Jan Krzysztof Blusztajn, Zhao Liu
Publikováno v:
The Journal of Neuroscience. 20:RC109-RC109
Choline is an essential nutrient for rats and humans, and its availability during fetal development has long-lasting cognitive effects (Blusztajn, 1998). We investigated the effects of prenatal choline supplementation on memory deficits associated wi
Autor:
John C. Neill, Carl E. Stafstrom, Matthew R. Sarkisian, Ariyuki Hori, Pushpa Tandon, A. R. Bolanos, Gregory L. Holmes, Yili Yang, Zhiqiang Liu
Publikováno v:
Electroencephalography and Clinical Neurophysiology. 99:P10