Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Lukasz P. Gondek"'
Autor:
Amy E. DeZern, Alexander J. Ambinder, Matthew D. Smith, Carol Ann Huff, Christian B. Gocke, Douglas E. Gladstone, Gabriel Ghiaur, William Dalton, Philip H. Imus, Mark J. Levis, Lukasz P. Gondek, Jonathan Webster, Ivana Gojo, Gabrielle T. Prince, Tania Jain, Margaret M. Showel, Ivan Borrello, Ravi Varadhan, Javier Bolaños-Meade, Hua-Ling Tsai, B. Douglas Smith, Nina Wagner-Johnston, Leo Luznik, Syed Abbas Ali, Richard Jones, Richard F. Ambinder, Ephraim J. Fuchs, Lode J. Swinnen
Publikováno v:
Clin Lymphoma Myeloma Leuk
Introduction Mutations in the IDH1 or IDH2 genes are detected in approximately 20% of cases of acute myeloid leukemia (AML). Few studies have examined the impact of IDH mutations in AML on allogeneic bone marrow transplant (alloBMT) outcomes. Patient
Autor:
Javier Bolaños-Meade, Mark Levis, Ivana Gojo, Syed Abbas Ali, Jonathan Webster, Richard J. Jones, Amy E. DeZern, Tania Jain, Douglas E. Gladstone, Lukasz P. Gondek, Nina D. Wagner-Johnston, W. Brian Dalton, Carol Ann Huff, B. Douglas Smith, Gabrielle T. Prince, Hua Ling Tsai, Gabriel Ghiaur, Christian B. Gocke, Leo Luznik, Ivan Borrello, Richard F. Ambinder, Philip H. Imus, Keith W. Pratz, Ephraim J. Fuchs, Margaret M. Showel, Lode J. Swinnen
Publikováno v:
Blood Adv
Allogeneic blood or marrow transplantation (alloBMT) is standard of care for adults with Philadelphia chromosome–positive acute lymphoblastic leukemia (Ph+ ALL) in first complete remission (CR1). The routine pretransplant and posttransplant use of
Autor:
Ivana Gojo, Judith E. Karp, Amanda L. Blackford, Steven D. Gore, Amy E. DeZern, Raul Montiel-Esparza, B. Douglas Smith, Keith W. Pratz, Howard Streicher, Hubert Hackl, Gabriel Ghiaur, Hanna A. Knaus, Mark J. Levis, Leo Luznik, Matthew C. Foster, Catherine C. Coombs, Joshua F. Zeidner, Margaret M. Showel, Lukasz P. Gondek, Gabrielle T. Prince, Amer M. Zeidan
Publikováno v:
Leukemia
An immunosuppressive microenvironment promoting leukemia cell immune escape plays an important role in the pathogenesis of AML. Through its interaction with cereblon, a substrate receptor for the E3 ubiquitin ligase complex, pomalidomide leads to sel
Autor:
Christopher S. Hourigan, Douglas E. Gladstone, Eric A. Gehrie, Javier Bolaños-Meade, Margaret M. Showel, Carol Ann Huff, Lukasz P. Gondek, Lode J. Swinnen, Gabriel Ghiaur, Ephraim J. Fuchs, Philip H. Imus, Gabrielle T. Prince, B. Douglas Smith, Mark J. Levis, Ivana Gojo, Jonathan Webster, Tania Jain, Richard F. Ambinder, Nina D. Wagner-Johnston, Abbas Abbas Ali, Amy E. DeZern, Ivan Borrello, Hua-Ling Tsai, Christian B. Gocke, Leo Luznik, William Brian Dalton, Richard J. Jones
Publikováno v:
Blood. 136:42-44
Background: Reduced-intensity induction (RII) with imatinib yields comparable outcomes to HyperCVAD with imatinib with fewer induction deaths and an improved CR rate in Ph+ ALL (Chalandon. Blood. 2015). Dasatinib with steroids also produces excellent
Autor:
Amy S. Duffield, Bryan C. Hambley, Jennifer Bynum, Philip H. Imus, Amy E. DeZern, Adam Luo, Michael B. Streiff, Thomas S. Kickler, Bo-Shiun Lai, Eugene Shenderov, John-William Sidhom, Alexander S. Baras, Alison R. Moliterno, Christian B. Gocke, Ingharan J. Siddarthan, Mark J. Levis, Lukasz P. Gondek
Publikováno v:
Blood. 136:10-12
Acute Promyelocytic Leukemia (APL) is a subtype of Acute Myeloid Leukemia (AML), classified by a translocation between chromosomes 15 and 17 [t(15;17)], that is notably distinguished clinically by a rapidly progressive and fatal course. Due to the ac
Autor:
Richard J. Jones, Theodoros Karantanos, Amy E. DeZern, Lukasz P. Gondek, Alison R. Moliterno, Tania Jain, Ravi Varadhan
Publikováno v:
Br J Haematol
Myelodysplastic syndrome/myeloproliferative neoplasm (MDS/MPN) overlap syndromes show a male predominance and men with MDS/MPN have worse outcomes, but it is unknown if the mutational burden differs between genders. We reviewed 167 patients with MDS/
Autor:
Amy E. DeZern, Christopher S. Hourigan, William Brian Dalton, Gabriel Ghiaur, Mark J. Levis, Ivana Gojo, Christian B. Gocke, Alexander J. Ambinder, B. Douglas Smith, Carol Ann Huff, Philip H. Imus, Margaret M. Showel, Jonathan Webster, Richard J. Jones, Javier Bolaños-Meade, Ivan Borrello, Abbas Abbas Ali, Lode J. Swinnen, Leo Luznik, Ephraim J. Fuchs, Douglas E. Gladstone, Lukasz P. Gondek, Gabrielle T. Prince, Richard F. Ambinder, Tania Jain, Nina D. Wagner-Johnston
Publikováno v:
Blood. 138:1846-1846
Background: The benefit of allogeneic blood or marrow transplantation (alloBMT) following myeloablative conditioning (MAC) in first complete remission (CR1) compared to chemotherapy has been demonstrated in a randomized trial for adults with acute ly
Autor:
Ravi Varadhan, Ivana Gojo, Margaret M. Showel, Hua-Ling Tsai, Theodoros Karantanos, Mark J. Levis, Tania Jain, Lukasz P. Gondek, Amy E. DeZern, Richard J. Jones
Publikováno v:
Blood. 136:40-40
INTRODUCTION: MDS/MPN are a group of clonal hematopoietic disorders with overlapping features of MDS and MPN, and include chronic myelomonocytic leukemia (CMML), atypical chronic myeloid leukemia (aCML), MDS/MPN-unclassifiable along with juvenile mye
Autor:
Joseph C. Murray, Stefan L. Zimmerman, Munjid Al Harthy, Vincent A. Pallazola, Jonathan Webster, Lukasz P. Gondek
Publikováno v:
American Journal of Hematology. 93:469-470
Autor:
Ghulam J. Mufti, Christine L. O'Keefe, Alan F. List, Anjali S. Advani, Paul Elson, Jungwon Huh, Azim M Mohamedali, Michael A. McDevitt, Mikkael A. Sekeres, Ramon V. Tiu, Jaroslaw P. Maciejewski, Ronald Paquette, Austin G. Kulasekararaj, Lukasz P. Gondek
Publikováno v:
Blood. 117:4552-4560
Single nucleotide polymorphism arrays (SNP-As) have emerged as an important tool in the identification of chromosomal defects undetected by metaphase cytogenetics (MC) in hematologic cancers, offering superior resolution of unbalanced chromosomal def