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pro vyhledávání: '"Lorna Rodriguez-Rodriguez"'
Autor:
Lorna Rodriguez-Rodriguez
Publikováno v:
Advancing the Science of Cancer in Latinos ISBN: 9783030292850
Precision medicine in oncology aims to treat a patient based on the molecular makeup of the individual’s tumor. Guidelines have already been adopted in certain tumor types for the use of targeted therapies as standard of care, including lung, colon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9f806b6e704d65614fa4a571a0ba9aef
https://doi.org/10.1007/978-3-030-29286-7_14
https://doi.org/10.1007/978-3-030-29286-7_14
Autor:
Elisa V. Bandera, Bo Qin, Lorna Rodriguez-Rodriguez, Valerie S. Lee, Lawrence H. Kushi, C. Bethan Powell
Publikováno v:
British Journal of Cancer
Background: Research on the effect of body mass index (BMI) on ovarian cancer survival is inconsistent, but previous studies did not consider the possible impact of ascites, bowel obstruction, or cachexia, which commonly occur in late-stage disease.
Autor:
Veronica Rojas, Darlene Gibbon, Aliza L. Leiser, Mira Hellmann, Kim M. Hirshfield, Robert S. DiPaola, Siraj M. Ali, Gregory Riedlinger, Vincent A. Miller, Julia A. Elvin, Sara Isani, Lorna Rodriguez-Rodriguez, Shridar Ganesan, Allison Wagreich
Publikováno v:
Gynecologic Oncology. 141:2-9
Objective To determine the feasibility and clinical utility of using comprehensive genomic profiling (CGP) in the course of clinical care to identify clinically relevant tumor genomic alterations for patients with either rare or refractory gynecologi
Autor:
June YiJuan Hou, Mihae Song, Eugenia Girda, David M Nelson, Ruth Stephenson, Malcolm Finlayson, Lorna Rodriguez-Rodriguez, Alexandre Buckley de Meritens, Aliza L. Leiser
Publikováno v:
Journal of Clinical Oncology. 38:e18040-e18040
e18040 Background: Therapeutic options for patients with recurrent platinum resistant ovarian cancer are scarce and represent an unmet need in ovarian cancer. Chemotherapy resistance has been linked to many CD44 pathways including P-glycoprotein medi
Autor:
Mehdi Kebria, Winnie S. Liang, Stephen J. Lee, Edward Wang, Nora Ruel, Byrne Lee, Ernest S. Han, Mark T. Wakabayashi, Wei-Chien Lin, Mihaela C. Cristea, Xiwei Wu, Hyejin Cho, Thanh H. Dellinger, Daphne Stewart, Lorna Rodriguez-Rodriguez, Mustafa Raoof
Publikováno v:
Journal of Clinical Oncology. 38:6060-6060
6060 Background: Advanced stage ovarian cancer patients benefit from hyperthermic intraperitoneal chemotherapy (HIPEC), prolonging overall survival by nearly 12 months. However, molecular changes triggered by HIPEC are not well characterized, and no
Autor:
Lorna Rodriguez-Rodriguez, Paula B. Caffrey, Muthu N. Kumaran, Mira Hellmann, Wilberto Nieves-Neira, Brian Buckley, Michael P. Kane, Murugesan Gounder, Darlene Gibbon, Gerald D. Frenkel, Mihae Song, Weichung Shih, Ami Vaidya
Publikováno v:
Gynecologic oncology. 150(3)
Purpose Preclinical studies performed in our laboratory have shown that high-dose selenium inhibits the development of carboplatin drug resistance in an ovarian cancer mouse xenograft model. Based on these data, as well as the potential serious toxic
Autor:
Lorna Rodriguez-Rodriguez, Wilberto Nieves-Neira, Darlene Gibbon, Allison Wagreich, Bernadette Cracchiolo, Mihae Song, Robert S. DiPaola, Ami Vaidya, Weichung Joe Shih, Mira Hellmann
Publikováno v:
International Journal of Gynecological Cancer. 24:1636-1641
Objective Overexpression of bcl-2 is a mechanism of drug resistance in cervical cancer. Agents that down-regulate bcl-2 may decrease tumor cell threshold and sensitize tumor cells to chemotherapy. The objective of this multi-institutional phase 2 tri
Autor:
James R. Hébert, Sara H. Olson, Lorna Rodriguez-Rodriguez, Elisa V. Bandera, Nitin Shivappa, Lisa E. Paddock
Publikováno v:
Nutrition (Burbank, Los Angeles County, Calif.). 46
Objective Diet may influence the development of ovarian cancer. Although it has been shown that inflammation plays an important etiologic role in ovarian carcinogenesis, little is known about the influence of the inflammatory potential of food consum
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 17, Iss 12, p 2113 (2016)
International Journal of Molecular Sciences, Vol 17, Iss 12, p 2113 (2016)
Epithelial ovarian cancer is a highly heterogeneous disease characterized by multiple histological subtypes. Molecular diversity has been shown to occur within specific histological subtypes of epithelial ovarian cancer, between different tumors of a
Autor:
Lorna Rodriguez-Rodriguez, A. Buckley de Meritens, Aliza L. Leiser, Eugenia Girda, David L. Nelson, Ruth Stephenson
Publikováno v:
Gynecologic Oncology. 154:93