Zobrazeno 1 - 10
of 155
pro vyhledávání: '"Kari Stefansson"'
Autor:
Ying Wang, Shinichi Namba, Esteban Lopera, Sini Kerminen, Kristin Tsuo, Kristi Läll, Masahiro Kanai, Wei Zhou, Kuan-Han Wu, Marie-Julie Favé, Laxmi Bhatta, Philip Awadalla, Ben Brumpton, Patrick Deelen, Kristian Hveem, Valeria Lo Faro, Reedik Mägi, Yoshinori Murakami, Serena Sanna, Jordan W. Smoller, Jasmina Uzunovic, Brooke N. Wolford, Cristen Willer, Eric R. Gamazon, Nancy J. Cox, Ida Surakka, Yukinori Okada, Alicia R. Martin, Jibril Hirbo, Kuan-Han H. Wu, Humaira Rasheed, Jibril B. Hirbo, Arjun Bhattacharya, Huiling Zhao, Esteban A. Lopera-Maya, Sinéad B. Chapman, Juha Karjalainen, Mitja Kurki, Maasha Mutaamba, Juulia J. Partanen, Ben M. Brumpton, Sameer Chavan, Tzu-Ting Chen, Michelle Daya, Yi Ding, Yen-Chen A. Feng, Christopher R. Gignoux, Sarah E. Graham, Whitney E. Hornsby, Nathan Ingold, Ruth Johnson, Triin Laisk, Kuang Lin, Jun Lv, Iona Y. Millwood, Priit Palta, Anita Pandit, Michael H. Preuss, Unnur Thorsteinsdottir, Matthew Zawistowski, Xue Zhong, Archie Campbell, Kristy Crooks, Geertruida H. de Bock, Nicholas J. Douville, Sarah Finer, Lars G. Fritsche, Christopher J. Griffiths, Yu Guo, Karen A. Hunt, Takahiro Konuma, Riccardo E. Marioni, Jansonius Nomdo, Snehal Patil, Nicholas Rafaels, Anne Richmond, Jonathan A. Shortt, Peter Straub, Ran Tao, Brett Vanderwerff, Kathleen C. Barnes, Marike Boezen, Zhengming Chen, Chia-Yen Chen, Judy Cho, George Davey Smith, Hilary K. Finucane, Lude Franke, Andrea Ganna, Tom R. Gaunt, Tian Ge, Hailiang Huang, Jennifer Huffman, Jukka T. Koskela, Clara Lajonchere, Matthew H. Law, Liming Li, Cecilia M. Lindgren, Ruth J.F. Loos, Stuart MacGregor, Koichi Matsuda, Catherine M. Olsen, David J. Porteous, Jordan A. Shavit, Harold Snieder, Richard C. Trembath, Judith M. Vonk, David Whiteman, Stephen J. Wicks, Cisca Wijmenga, John Wright, Jie Zheng, Xiang Zhou, Michael Boehnke, Daniel H. Geschwind, Caroline Hayward, Eimear E. Kenny, Yen-Feng Lin, Hilary C. Martin, Sarah E. Medland, Aarno V. Palotie, Bogdan Pasaniuc, Kari Stefansson, David A. van Heel, Robin G. Walters, Sebastian Zöllner, Cristen J. Willer, Mark J. Daly, Benjamin M. Neale
Publikováno v:
Cell Genomics, Vol 3, Iss 1, Pp 100241- (2023)
Summary: Polygenic risk scores (PRSs) have been widely explored in precision medicine. However, few studies have thoroughly investigated their best practices in global populations across different diseases. We here utilized data from Global Biobank M
Externí odkaz:
https://doaj.org/article/ab70f310dfdd4e7dbc3dc7fc2ba9b939
Autor:
Brynjar O. Jensson, Sif Hansdottir, Gudny A. Arnadottir, Gerald Sulem, Ragnar P. Kristjansson, Asmundur Oddsson, Stefania Benonisdottir, Hakon Jonsson, Agnar Helgason, Jona Saemundsdottir, Olafur T. Magnusson, Gisli Masson, Gudmundur A. Thorisson, Adalbjorg Jonasdottir, Aslaug Jonasdottir, Asgeir Sigurdsson, Ingileif Jonsdottir, Vigdis Petursdottir, Jon R. Kristinsson, Daniel F. Gudbjartsson, Unnur Thorsteinsdottir, Reynir Arngrimsson, Patrick Sulem, Gunnar Gudmundsson, Kari Stefansson
Publikováno v:
BMC Medical Genetics, Vol 18, Iss 1, Pp 1-5 (2017)
Abstract Background Rare missense mutations in the gene encoding coatomer subunit alpha (COPA) have recently been shown to cause autoimmune interstitial lung, joint and kidney disease, also known as COPA syndrome, under a dominant mode of inheritance
Externí odkaz:
https://doaj.org/article/17b82beed8f640dc8ff4b312e80a5ff4
Autor:
Gudny A. Arnadottir, Brynjar O. Jensson, Sigurdur E. Marelsson, Gerald Sulem, Asmundur Oddsson, Ragnar P. Kristjansson, Stefania Benonisdottir, Sigurjon A. Gudjonsson, Gisli Masson, Gudmundur A. Thorisson, Jona Saemundsdottir, Olafur Th. Magnusson, Adalbjorg Jonasdottir, Aslaug Jonasdottir, Asgeir Sigurdsson, Daniel F. Gudbjartsson, Unnur Thorsteinsdottir, Reynir Arngrimsson, Patrick Sulem, Kari Stefansson
Publikováno v:
BMC Medical Genetics, Vol 18, Iss 1, Pp 1-5 (2017)
Abstract Background Epileptic encephalopathies are a group of childhood epilepsies that display high phenotypic and genetic heterogeneity. The recent, extensive use of next-generation sequencing has identified a large number of genes in epileptic enc
Externí odkaz:
https://doaj.org/article/3ecb8fc5078b40faa4921489a2b36192
Autor:
Hilma Holm, Kristbjorg Gunnarsdottir, Michael L. Frigge, Gudmundur Thorgeirsson, Erna V. Ivarsdottir, Thorunn Rafnar, Saedis Saevarsdottir, Helgi Jonsson, Unnur Thorsteinsdottir, Gudmundur L. Norddahl, Sigrun H. Lund, Gyda Bjornsdottir, Kari Stefansson, Daniel F. Gudbjartsson, Patrick Sulem, Magnus I. Magnusson, I. Jonsdottir, Thorvaldur Ingvarsson, Unnur Styrkarsdottir
Publikováno v:
Arthritis & Rheumatology (Hoboken, N.j.)
Objective Biomarkers for diagnosis and progression of osteoarthritis (OA) are lacking. This study was undertaken to identify circulating biomarkers for OA that could predict disease occurrence and/or progression to joint replacement. Methods Using th
Autor:
Sara A. Paciga, Richard M. Weinshilboum, Andrew M. McIntosh, Tim B. Bigdeli, Stephanie H. Witt, Sven Cichon, Glyn Lewis, Henning Teismann, Brenda W.J.H. Penninx, Gerome Breen, Roseann E. Peterson, Saira Saeed Mirza, Diego Albani, Lisa Jones, Andreas J. Forstner, Sara Mostafavi, Julien Bryois, Qingqin S. Li, Kenneth S. Kendler, Thomas Damm Als, Fernando S. Goes, Marie Bækvad-Hansen, Nancy L. Pedersen, Gianluigi Forloni, Per Qvist, Carsten Horn, Per Hoffmann, Steven P. Hamilton, Georg Homuth, Michael Gill, Julien Mendlewicz, Katharina Domschke, Volker Arolt, Adrian I. Campos, Christine Søholm Hansen, Scott D. Gordon, Hogni Oskarsson, Peter McGuffin, Oliver Pain, Eric Jorgenson, Victoria S. Marshe, Stacy Steinberg, Bertram Müller-Myhsok, Mark Adams, J. Raymond DePaulo, Rick Jansen, Katherine J. Aitchison, Vassily Trubetskoy, Henry Völzke, Manuel Mattheisen, Bernard Ng, James A. Knowles, Dorret I. Boomsma, Tracy Air, Elisabeth B. Binder, Ian B. Hickie, Christel M. Middeldorp, Tõnu Esko, David M. Hougaard, E.J.C. de Geus, Toni-Kim Clarke, Helena Gaspar, Bernhard T. Baune, Abdel Abdellaoui, Engilbert Sigurdsson, Andres Metspalu, Klaus Berger, Jorge A. Quiroz, Patrick F. Sullivan, Aartjan T.F. Beekman, Thomas Hansen, Panagiotis Ferentinos, Jürgen Wellmann, Miguel E. Rentería, Daniel Umbricht, Marcella Rietschel, Stanley I. Shyn, Chiara Fabbri, Hreinn Stefansson, Jerome C. Foo, Daniel Souery, Zoltán Kutalik, Yu-Li Liu, Paul F. O'Reilly, Michael John Owen, Nese Direk, Douglas F. Levinson, Stuart Montgomery, Hamdi Mbarek, David M. Howard, Guido Bondolfi, Lucía Colodro-Conde, Pippa A. Thomson, Merete Nordentoft, Stefan Kloiber, Yunpeng Wang, Michael Conlon O'Donovan, Grant C.B. Sinnamon, Alexander Viktorin, Hilary K. Finucane, Esben Agerbo, Stefan Herms, Markus M. Nöthen, Till F. M. Andlauer, Divya Mehta, Bradley T. Webb, Joanna M. Biernacka, David J. Porteous, Jordan W. Smoller, Jonathan R. I. Coleman, Dean F. MacKinnon, Farnush Farhadi Hassan Kiadeh, Baptiste Couvy-Duchesne, Evelin Mihailov, Eleanor M. Wigmore, Franziska Degenhardt, Jianxin Shi, Dale R. Nyholt, Enda M. Byrne, Stephan Ripke, Ole Mors, Patrik K. E. Magnusson, Eric J. Lenze, Warren W. Kretzschmar, Masaki Kato, Marcus Ising, Ian Jones, Lynsey S. Hall, Wouter J. Peyrot, Ling Shen, Nader Perroud, Na Cai, Maciej Trzaskowski, Matthias Nauck, Isaac S. Kohane, Enrico Domenici, Fabian Streit, James L. Kennedy, Peter M. Visscher, Valentina Escott-Price, Donald J. MacIntyre, Enrique Castelao, Margarita Rivera, Mojca Z. Dernovsek, John P. Rice, Joseph Zohar, Gail Davies, Andrew C. Heath, Josef Frank, Wesley K. Thompson, Caroline Hayward, Penelope A. Lind, Thorgeir E. Thorgeirsson, Rudolf Uher, Jana Strohmaier, Henriette N. Buttenschøn, Erin C. Dunn, Jonas Bybjerg-Grauholm, Alexander Teumer, Jakob Grove, Eske M. Derks, Nicholas G. Martin, Jodie N. Painter, Myrna M. Weissman, Preben Bo Mortensen, Michel G. Nivard, Catherine Schaefer, Yihan Li, Daniel J. Smith, Shih-Jen Tsai, Niamh Mullins, Jian Yang, Marianne Giørtz Pedersen, Dan Rujescu, Thomas G. Schulze, Lili Milani, Yuri Milaneschi, Giorgio Pistis, James B. Potash, Neven Henigsberg, Nicholas John Craddock, Karen Hodgson, Silviu-Alin Bacanu, Shantel Weinsheimer, Charles F. Reynolds, Johannes H. Smit, Gonneke Willemsen, Futao Zhang, Henning Tiemeier, Grant W. Montgomery, Martin Preisig, Udo Dannlowski, Thalia C. Eley, Thomas Werge, Katherine E. Tansey, Jane H. Christensen, Julia Kraft, Ian J. Deary, Cathryn M. Lewis, Sarah E. Medland, André G. Uitterlinden, Daniel J. Müller, Carsten Bøcker Pedersen, Gustavo Turecki, Hans J. Grabe, Matthew Traylor, Brien P. Riley, Roy H. Perlis, Patrick J. McGrath, Conor V. Dolan, Hualin S. Xi, Jonathan Marchini, Robert A. Schoevers, Albert M. van Hemert, Anders D. Børglum, Susanne Lucae, Jouke-Jan Hottenga, Kari Stefansson, Benoit H. Mulsant, Francis M. Mondimore, Naomi R. Wray, Yang Wu, Wolfgang Maier, Danielle Posthuma, Annamaria Cattaneo, Gregory E. Crawford, Siegfried Kasper, Alessandro Serretti, Tania Carrillo-Roa, Robert Maier, Pamela A. F. Madden, Eva C. Schulte, Jens Treutlein, Joanna Hauser, Sandra Van der Auwera
Publikováno v:
GSRD Consortium & Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium 2022, ' Identifying the Common Genetic Basis of Antidepressant Response ', Biological Psychiatry Global Open Science, vol. 2, no. 2, pp. 115-126 . https://doi.org/10.1016/j.bpsgos.2021.07.008
Pain, O, Hodgson, K, Trubetskoy, V, Ripke, S, Marshe, V S, Adams, M J, Byrne, E M, Campos, A I, Carrillo-Roa, T, Cattaneo, A, Als, T D, Souery, D, Dernovsek, M Z, Fabbri, C, Hayward, C, Henigsberg, N, Hauser, J, Kennedy, J L, Lenze, E J, Lewis, G, Müller, D J, Martin, N G, Mulsant, B H, Mors, O, Perroud, N, Porteous, D J, Rentería, M E, Reynolds, C F, Rietschel, M, Uher, R, Wigmore, E M, Maier, W, Wray, N R, Aitchison, K J, Arolt, V, Baune, B T, Biernacka, J M, Bondolfi, G, Domschke, K, Kato, M, Li, Q S, Liu, Y-L, Serretti, A, Tsai, S-J, Turecki, G & Weinshilboum, R & McIntosh, A M & Lewis, C M 2022, ' Identifying the Common Genetic Basis of Antidepressant Response ', Biological psychiatry global open science, vol. 2, no. 2, pp. 115-126 . https://doi.org/10.1016/j.bpsgos.2021.07.008
Biological Psychiatry Global Open Science, 2(2), 115-126. Elsevier BV
McIntosh, A M, Lewis, C M, GSRD Consortium & Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium 2022, ' Identifying the Common Genetic Basis of Antidepressant Response ', Biological Psychiatry: Global Open Science, vol. 2, no. 2, pp. 115-126 . https://doi.org/10.1016/j.bpsgos.2021.07.008
Biological psychiatry: global open science 2(2), 115-126 (2022). doi:10.1016/j.bpsgos.2021.07.008
Biological Psychiatry Global Open Science, 2(2), 115-126
Biological Psychiatry Global Open Science, 2(2), 115-126. Elsevier
Pain, O, Hodgson, K, Trubetskoy, V, Ripke, S, Marshe, V S, Adams, M J, Byrne, E M, Campos, A I, Carrillo-Roa, T, Cattaneo, A, Als, T D, Souery, D, Dernovsek, M Z, Fabbri, C, Hayward, C, Henigsberg, N, Hauser, J, Kennedy, J L, Lenze, E J, Lewis, G, Müller, D J, Martin, N G, Mulsant, B H, Mors, O, Perroud, N, Porteous, D J, Rentería, M E, Reynolds, C F, Rietschel, M, Uher, R, Wigmore, E M, Maier, W, Wray, N R, Aitchison, K J, Arolt, V, Baune, B T, Biernacka, J M, Bondolfi, G, Domschke, K, Kato, M, Li, Q S, Liu, Y-L, Serretti, A, Tsai, S-J, Turecki, G & Weinshilboum, R & McIntosh, A M & Lewis, C M 2022, ' Identifying the Common Genetic Basis of Antidepressant Response ', Biological psychiatry global open science, vol. 2, no. 2, pp. 115-126 . https://doi.org/10.1016/j.bpsgos.2021.07.008
Biological Psychiatry Global Open Science, 2(2), 115-126. Elsevier BV
McIntosh, A M, Lewis, C M, GSRD Consortium & Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium 2022, ' Identifying the Common Genetic Basis of Antidepressant Response ', Biological Psychiatry: Global Open Science, vol. 2, no. 2, pp. 115-126 . https://doi.org/10.1016/j.bpsgos.2021.07.008
Biological psychiatry: global open science 2(2), 115-126 (2022). doi:10.1016/j.bpsgos.2021.07.008
Biological Psychiatry Global Open Science, 2(2), 115-126
Biological Psychiatry Global Open Science, 2(2), 115-126. Elsevier
Background: Antidepressants are a first-line treatment for depression. However, only a third of individuals experience remission after the first treatment. Common genetic variation, in part, likely regulates antidepressant response, yet the success o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c907fa773f30e9647559b297edd74e1d
https://pure.au.dk/portal/da/publications/identifying-the-common-genetic-basis-of-antidepressant-response(7255846b-ac58-462b-be46-77e5e1468621).html
https://pure.au.dk/portal/da/publications/identifying-the-common-genetic-basis-of-antidepressant-response(7255846b-ac58-462b-be46-77e5e1468621).html
Autor:
Tove Fall, Anubha Mahajan, Dmitry Shungin, B. Balkau, Gerjan Navis, A. Metspalu, Anneli Pouta, Andrew A. Hicks, Ilja M. Nolte, Ian Ford, Aroon D. Hingorani, Stefan R Bornstein, Anuj Goel, Rona J. Strawbridge, Niek Verweij, Sarah H. Wild, Patricia B. Munroe, T.B. Harris, Jaana Lindström, Johnson Pcd., Nita G. Forouhi, Pierre Meneton, Patricia A. Peyser, Sarin A-P., Andrea Ganna, Timothy M. Frayling, Patrik K. E. Magnusson, Joanne M. Meyer, Yongmei Liu, Jeanette M. Stafford, Christian Herder, L Zudina, Maria G. Stathopoulou, May E. Montasser, Nicholas D. Hastie, Inês Barroso, Schwarz Peh., James B. Meigs, Perttu Salo, George Davey Smith, Gonneke Willemsen, Christopher J. Groves, Erik P A Van Iperen, M. A. Province, Veikko Salomaa, Naveed Sattar, Serena Sanna, Maria Dimitriou, Joop Jukema, Ulrika Krus, Albert V. Smith, Markku Laakso, James F. Wilson, George Nicholson, Loic Yengo, Tatijana Zemunik, Per Eriksson, Harold Snieder, Peter P. Pramstaller, Claudia Langenberg, R. Rauramaa, Alan R. Shuldiner, Pau Navarro, Veronique Vitart, Ross M. Fraser, Aaron Isaacs, C. Lecoeur, Jesper R. Gådin, Jackie F. Price, Letizia Marullo, L.F. Bielak, Sirkka Keinänen-Kiukaanniemi, Amélie Bonnefond, Michael Stumvoll, Alessia Faggian, Anke Tönjes, Tomohiro Tanaka, Wieland Kiess, Harry Campbell, Josée Dupuis, David Altshuler, João Fadista, Winfried März, G K Hovingh, Thomas Illig, Toby Johnson, H Grallert, Kari Stefansson, Reedik Mägi, Palmer Cna., de Geus Ejcn., Martina Müller-Nurasyid, Karen Kapur, Philippe Froguel, Dorret I. Boomsma, Anders Franco-Cereceda, Marcus E. Kleber, Boehnke M, Olga D. Carlson, Ozren Polasek, Andrew P. Morris, Alex S. F. Doney, Najaf Amin, Sara M. Willems, Vilmundur Gudnason, Jose C. Florez, Jeffery R. O'Connell, Nancy L. Pedersen, T. Saaristo, Wolffenbuttel Bhr., M. I. J. Uusitupa, Longda Jiang, Iva Miljkovic, James S. Pankow, Caroline Hayward, Hugh Watkins, Vasiliki Lagou, Johanna Kuusisto, Jaakko Tuomilehto, Alan F. Wright, Josephine M. Egan, Perry Jrb., C M van Duijn, Valeriya Lyssenko, Leif Groop, Stefania Bandinelli, Nigel W. Rayner, Tõnu Esko, Stela McLachlan, Momoko Horikoshi, Eric Boerwinkle, Rick Jansen, Richard N. Bergman, Gudmar Thorleifsson, Lyle J. Palmer, Vilmantas Giedraitis, Peter Kovacs, Nicholas J. Wareham, Luigi Ferrucci, N J Timpson, D Rybin, Anne U. Jackson, Tiinamaija Tuomi, Gonçalo R. Abecasis, Harst Pvd., Meena Kumari, Albert Hofman, Chiara Scapoli, Evelin Mihailov, Josine L. Min, Anders Hamsten, Hottenga J-J., Loos Rjf., Lars Lind, Ulf de Faire, Jaakko Kaprio, Guo Li, Beate St Pourcain, C Gieger, Amanda J. Bennett, Anna Ulrich, Nabila Bouatia-Naji, Satu Männistö, Antigone S. Dimas, Jarvelin M-R., Günther Silbernagel, F Karpe, A. Körner, David S. Siscovick, M Blüher, Rebecca J. Webster, Erik Ingelsson, Susan Campbell, Mika Kivimäki, Laura J. Rasmussen-Torvik, Heikki A. Koistinen, Sophie Visvikis-Siest, Bernhard O. Boehm, Inga Prokopenko, Ping An, Emmanouil T. Dermitzakis, Cecilia M. Lindgren, Kardia Slr., Richa Saxena, Igor Rudan, Richard M. Watanabe, Jian'an Luan, Marika Kaakinen, Shin S-Y., George Dedoussis, Panagiotis Deloukas, Mark I. McCarthy, Barbara Thorand, B.W.J.H. Penninx, Peter Vollenweider, Paul W. Franks, Leena Kinnunen, Markus Perola, Yvonne Boettcher, Timo A. Lakka, Nicole Soranzo, Stavroula Kanoni, Bakker Sjl., Winkelmann Br
Publikováno v:
Nature Communications
Nature Communications, Nature Publishing Group, 2021, 12 (1), pp.24. ⟨10.1038/s41467-020-19366-9⟩
Nature communications, 12(1):24. Nature Publishing Group
Meta-Analyses of Glucose and Insulin-related traits Consortium (MAGIC) 2021, ' Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability ', Nature Communications, vol. 12, no. 1, 24 . https://doi.org/10.1038/s41467-020-19366-9, https://doi.org/10.1038/s41467-020-19366-9
Nature Communications, 2021, 12 (1), pp.24. ⟨10.1038/s41467-020-19366-9⟩
Nature Communications, 12(1):24, 1-18. Nature Publishing Group
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
Nature Communications, 12(1):24. Nature Publishing Group
Meta-Analyses of Glucose and Insulin-related traits Consortium (MAGIC) 2021, ' Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability ', Nature Communications, vol. 12, no. 1, 24 . https://doi.org/10.1038/s41467-020-19366-9
Nature Communications, 12(1):24. Nature Publishing Group UK
Lagou, V, Mägi, R, Hottenga, J J, Jansen, R, Min, J L, Willemsen, G, De Geus, E J C N, Penninx, B W, Boomsma, D I, Barroso, I, Morris, A P, Prokopenko, I & MAGIC Collaboration 2021, ' Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability ', Nature Communications, vol. 12, no. 1, 24, pp. 1-18 . https://doi.org/10.1038/s41467-020-19366-9
Min, J L, St Pourcain, M U B, Timpson, N J, Davey Smith, G, Prokopenko, I & et al. 2021, ' Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability ', Nature Communications, vol. 12, 24 . https://doi.org/10.1038/s41467-020-19366-9
2021, ' Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability ', Nature Communications, vol. 12, no. 1, 24 . https://doi.org/10.1038/s41467-020-19366-9, https://doi.org/10.1038/s41467-021-21276-3
Nature communications, vol. 12, no. 1, pp. 24
Nature Communications, 12(1). NATURE RESEARCH
Nature Communications, Nature Publishing Group, 2021, 12 (1), pp.24. ⟨10.1038/s41467-020-19366-9⟩
Nature communications, 12(1):24. Nature Publishing Group
Meta-Analyses of Glucose and Insulin-related traits Consortium (MAGIC) 2021, ' Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability ', Nature Communications, vol. 12, no. 1, 24 . https://doi.org/10.1038/s41467-020-19366-9, https://doi.org/10.1038/s41467-020-19366-9
Nature Communications, 2021, 12 (1), pp.24. ⟨10.1038/s41467-020-19366-9⟩
Nature Communications, 12(1):24, 1-18. Nature Publishing Group
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
Nature Communications, 12(1):24. Nature Publishing Group
Meta-Analyses of Glucose and Insulin-related traits Consortium (MAGIC) 2021, ' Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability ', Nature Communications, vol. 12, no. 1, 24 . https://doi.org/10.1038/s41467-020-19366-9
Nature Communications, 12(1):24. Nature Publishing Group UK
Lagou, V, Mägi, R, Hottenga, J J, Jansen, R, Min, J L, Willemsen, G, De Geus, E J C N, Penninx, B W, Boomsma, D I, Barroso, I, Morris, A P, Prokopenko, I & MAGIC Collaboration 2021, ' Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability ', Nature Communications, vol. 12, no. 1, 24, pp. 1-18 . https://doi.org/10.1038/s41467-020-19366-9
Min, J L, St Pourcain, M U B, Timpson, N J, Davey Smith, G, Prokopenko, I & et al. 2021, ' Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability ', Nature Communications, vol. 12, 24 . https://doi.org/10.1038/s41467-020-19366-9
2021, ' Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability ', Nature Communications, vol. 12, no. 1, 24 . https://doi.org/10.1038/s41467-020-19366-9, https://doi.org/10.1038/s41467-021-21276-3
Nature communications, vol. 12, no. 1, pp. 24
Nature Communications, 12(1). NATURE RESEARCH
Differences between sexes contribute to variation in the levels of fasting glucose and insulin. Epidemiological studies established a higher prevalence of impaired fasting glucose in men and impaired glucose tolerance in women, however, the genetic c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5783e9d2579548e3deb52d1bbdf19db
https://hal.univ-lorraine.fr/hal-03105716
https://hal.univ-lorraine.fr/hal-03105716
Autor:
Bruce Pike, Masaki Fukunaga, Erik G. Jönsson, Robin M. Murray, Abdel Abdellaoui, Christopher R.K. Ching, Simon E. Fisher, Henry Brodaty, James Rucker, Gary Donohoe, Robin Bülow, Greig I. de Zubicaray, Stefan Johansson, Katrin Amunts, Katharina Wittfeld, Arvid Lundervold, Vincent Frouin, Ida E Sønderby, Tetyana Zayats, Carlos Prieto, Vince D. Calhoun, Anders M. Dale, Hilleke E. Hulshoff Pol, Tomáš Paus, Lars Nyberg, David C. Glahn, Benedicto Crespo-Facorro, Nicholas B. Blackburn, Gunter Schumann, Thomas Espeseth, Lars T. Westlye, Loes M. Olde Loohuis, Dan J. Stein, Dorret I. Boomsma, Dennis van der Meer, Stefan Ehrlich, Stephanie Le Hellard, Elena Shumskaya, Tiago Reis Marques, Manon Bernard, Nicholas G. Martin, Jan Haavik, Rachel M. Brouwer, Simone Ciufolini, Marta Di Forti, Shareefa Dalvie, Perminder S. Sachdev, Oleksandr Frei, Emma Knowles, Samuel R. Mathias, Else Eising, Ingrid Agartz, Clara Moreau, Nicola J. Armstrong, Dennis van 't Ent, Norman Delanty, Christian K. Tamnes, Evangelos Vassos, Marianne Bernadette van den Bree, Christiane Jockwitz, Magnus O. Ulfarsson, Katie L. McMahon, Allan F. McRae, Thomas W. Mühleisen, Peter R. Schofield, Sarah E. Medland, Hreinn Stefansson, David Edmund Johannes Linden, Céline S. Reinbold, Sanjay M. Sisodiya, Wei Wen, Paul M. Thompson, Jouke-Jan Hottenga, Paola Dazzan, Kari Stefansson, Alexander Teumer, Eco J. C. de Geus, Per Hoffmann, Neda Jahanshad, Jingyu Liu, Joanne E. Curran, Juan M. Peralta, Laurena Holleran, Ana I. Silva, Asta Håberg, Thomas Gareau, Karen A. Mather, Srdjan Djurovic, Lachlan T. Strike, Anbupalam Thalamuthu, Hans J. Grabe, Ryota Hashimoto, Tormod Fladby, Manon H.J. Hillegers, Tobias Kaufmann, Masataka Kikuchi, Jan Egil Nordvik, Zdenka Pausova, Omar Gustafsson, Gianpiero L. Cavalleri, Margaret J. Wright, Nynke A. Groenewold, Wiepke Cahn, Astri J. Lundervold, Michael John Owen, Diana Tordesillas-Gutiérrez, Sven Cichon, Sonja M C de Zwarte, Torgeir Moberget, Vidar M. Steen, John Blangero, Derek W. Morris, Roel A. Ophoff, Derrek P. Hibar, Andrew J. Schork, Anouk den Braber, Jayne Y. Hehir-Kwa, G. Bragi Walters, Micael Andersson, Sigrid Botne Sando, Joanne L. Doherty, Aiden Corvin, Sébastien Jacquemont, Erin Burke Quinlan, John B.J. Kwok, Anne Uhlmann, David Ames, Jean Shin, Svenja Caspers, Sylvane Desrivières, Ole A. Andreassen, Masashi Ikeda
Publikováno v:
JAMA Psychiatry, 77(4), 420-430. American Medical Association
JAMA Psychiatry
JAMA psychiatry 77(4), 420 (2020). doi:10.1001/jamapsychiatry.2019.3779
Digital.CSIC. Repositorio Institucional del CSIC
instname
JAMA psychiatry 77(4), 420-430 (2020). doi:10.1001/jamapsychiatry.2019.3779
JAMA Psychiatry, 77, 4, pp. 420-430
van der Meer, D, Abdellaoui, A, Boomsma, D I, de Geus, E J C, den Braber, A, Hottenga, J-J, van 't Ent, D, Andreassen, O A & Writing Committee for the ENIGMA-CNV Working Group 2020, ' Association of Copy Number Variation of the 15q11.2 BP1-BP2 Region With Cortical and Subcortical Morphology and Cognition ', JAMA Psychiatry, vol. 77, no. 4, pp. 420-430 . https://doi.org/10.1001/jamapsychiatry.2019.3779
JAMA Psychiatry, 77, 420-430
van der Meer, D, Sønderby, I E, Kaufmann, T, Walters, G B, Abdellaoui, A, Ames, D, Amunts, K, Andersson, M, Armstrong, N J, Bernard, M, Blackburn, N B, Blangero, J, Boomsma, D I, Brodaty, H, Brouwer, R M, Bülow, R, Cahn, W, Calhoun, V D, Caspers, S, Cavalleri, G L, Ching, C R K, Cichon, S, Ciufolini, S, Corvin, A, Crespo-Facorro, B, Curran, J E, Dalvie, S, Dazzan, P, de Geus, E J C, de Zubicaray, G I, de Zwarte, S M C, Delanty, N, den Braber, A, Desrivieres, S, di Forti, M, Doherty, J L, Donohoe, G, Ehrlich, S, Eising, E, Espeseth, T, Fisher, S E, Fladby, T, Frei, O, Frouin, V, Fukunaga, M, Gareau, T, Glahn, D C, Grabe, H J, Groenewold, N A, Gústafsson, Ó, Haavik, J, Haberg, A K, Hashimoto, R, Hehir-Kwa, J Y, Hibar, D P, Hillegers, M H J, Hoffmann, P, Holleran, L, Hottenga, J-J, Hulshoff Pol, H E, Ikeda, M, Jacquemont, S B, Jahanshad, N, Jockwitz, C, Johansson, S, Jönsson, E G, Kikuchi, M, Knowles, E E M, Kwok, J B, le Hellard, S, Linden, D E J, Liu, J, Lundervold, A, Lundervold, A J, Martin, N G, Mather, K A, Mathias, S R, McMahon, K L, McRae, A F, Medland, S E, Moberget, T, Moreau, C, Morris, D W, Mühleisen, T W, Murray, R M, Nordvik, J E, Nyberg, L, Olde Loohuis, L M, Ophoff, R A, Owen, M J, Paus, T, Pausova, Z, Peralta, J M, Pike, B, Prieto, C, Quinlan, E B, Reinbold, C L S, Reis Marques, T, Rucker, J J H, Sachdev, P S, Sando, S B, Schofield, P R, Schork, A J, Schumann, G, Shin, J, Shumskaya, E, Silva, A I, Sisodiya, S M, Steen, V M, Stein, D J, Strike, L T, Tamnes, C K, Teumer, A, Thalamuthu, A, Tordesillas-Gutiérrez, D, Uhlmann, A, Úlfarsson, M Ö, van 't Ent, D, van den Bree, M B M, Vassos, E, Wen, W, Wittfeld, K, Wright, M J, Zayats, T, Dale, A M, Djurovic, S, Agartz, I, Westlye, L T, Stefánsson, H, Stefánsson, K R, Thompson, P M & Andreassen, O A 2020, ' Association of Copy Number Variation of the 15q11.2 BP1-BP2 Region with Cortical and Subcortical Morphology and Cognition ', JAMA Psychiatry, vol. 77, no. 4, pp. 420-430 . https://doi.org/10.1001/jamapsychiatry.2019.3779
JAMA Psychiatry
JAMA psychiatry 77(4), 420 (2020). doi:10.1001/jamapsychiatry.2019.3779
Digital.CSIC. Repositorio Institucional del CSIC
instname
JAMA psychiatry 77(4), 420-430 (2020). doi:10.1001/jamapsychiatry.2019.3779
JAMA Psychiatry, 77, 4, pp. 420-430
van der Meer, D, Abdellaoui, A, Boomsma, D I, de Geus, E J C, den Braber, A, Hottenga, J-J, van 't Ent, D, Andreassen, O A & Writing Committee for the ENIGMA-CNV Working Group 2020, ' Association of Copy Number Variation of the 15q11.2 BP1-BP2 Region With Cortical and Subcortical Morphology and Cognition ', JAMA Psychiatry, vol. 77, no. 4, pp. 420-430 . https://doi.org/10.1001/jamapsychiatry.2019.3779
JAMA Psychiatry, 77, 420-430
van der Meer, D, Sønderby, I E, Kaufmann, T, Walters, G B, Abdellaoui, A, Ames, D, Amunts, K, Andersson, M, Armstrong, N J, Bernard, M, Blackburn, N B, Blangero, J, Boomsma, D I, Brodaty, H, Brouwer, R M, Bülow, R, Cahn, W, Calhoun, V D, Caspers, S, Cavalleri, G L, Ching, C R K, Cichon, S, Ciufolini, S, Corvin, A, Crespo-Facorro, B, Curran, J E, Dalvie, S, Dazzan, P, de Geus, E J C, de Zubicaray, G I, de Zwarte, S M C, Delanty, N, den Braber, A, Desrivieres, S, di Forti, M, Doherty, J L, Donohoe, G, Ehrlich, S, Eising, E, Espeseth, T, Fisher, S E, Fladby, T, Frei, O, Frouin, V, Fukunaga, M, Gareau, T, Glahn, D C, Grabe, H J, Groenewold, N A, Gústafsson, Ó, Haavik, J, Haberg, A K, Hashimoto, R, Hehir-Kwa, J Y, Hibar, D P, Hillegers, M H J, Hoffmann, P, Holleran, L, Hottenga, J-J, Hulshoff Pol, H E, Ikeda, M, Jacquemont, S B, Jahanshad, N, Jockwitz, C, Johansson, S, Jönsson, E G, Kikuchi, M, Knowles, E E M, Kwok, J B, le Hellard, S, Linden, D E J, Liu, J, Lundervold, A, Lundervold, A J, Martin, N G, Mather, K A, Mathias, S R, McMahon, K L, McRae, A F, Medland, S E, Moberget, T, Moreau, C, Morris, D W, Mühleisen, T W, Murray, R M, Nordvik, J E, Nyberg, L, Olde Loohuis, L M, Ophoff, R A, Owen, M J, Paus, T, Pausova, Z, Peralta, J M, Pike, B, Prieto, C, Quinlan, E B, Reinbold, C L S, Reis Marques, T, Rucker, J J H, Sachdev, P S, Sando, S B, Schofield, P R, Schork, A J, Schumann, G, Shin, J, Shumskaya, E, Silva, A I, Sisodiya, S M, Steen, V M, Stein, D J, Strike, L T, Tamnes, C K, Teumer, A, Thalamuthu, A, Tordesillas-Gutiérrez, D, Uhlmann, A, Úlfarsson, M Ö, van 't Ent, D, van den Bree, M B M, Vassos, E, Wen, W, Wittfeld, K, Wright, M J, Zayats, T, Dale, A M, Djurovic, S, Agartz, I, Westlye, L T, Stefánsson, H, Stefánsson, K R, Thompson, P M & Andreassen, O A 2020, ' Association of Copy Number Variation of the 15q11.2 BP1-BP2 Region with Cortical and Subcortical Morphology and Cognition ', JAMA Psychiatry, vol. 77, no. 4, pp. 420-430 . https://doi.org/10.1001/jamapsychiatry.2019.3779
ENIGMA-CNV Working Group: van der Meer, Dennis; Sonderby, Ida E; Kaufmann, Tobias; Walters, G Bragi; Abdellaoui, Abdel; Ames, David; Amunts, Katrin; Andersson, Micael; Armstrong, Nicola J; Bernard, Manon; Blackburn, Nicholas B; Blangero, John; Boomsm
Autor:
Svati H. Shah, Olle Melander, Neneh Sallah, Quinn S. Wells, Jerome I. Rotter, Faye Zhao, Charlotte Andersson, Guðmundur Thorgeirsson, Ghazaleh Fatemifar, Alex S. F. Doney, Michael E. Dunn, David E. Lanfear, Ian Ford, Eric Boersma, Sonia Shah, Christopher Newton-Cheh, Douglas L. Mann, Niek Verweij, Carolina Roselli, Laura M. Yerges-Armstrong, Jian Yang, Christian Torp-Pedersen, Veikko Salomaa, Mary L. Biggs, Alaa Shalaby, Christoph Nowak, Stefan Gross, Patrick T. Ellinor, Mari Liis Tammesoo, Diane T. Smelser, Peter M. Visscher, Hans L. Hillege, Ruth C. Lovering, Honghuang Lin, Colin N. A. Palmer, Louis Philippe Lemieux Perreault, Jeffrey Brandimarto, Uwe Völker, Perttu Salo, Andrea Koekemoer, Rebecca Gutmann, Åsa K. Hedman, Nilesh J. Samani, Heming Xing, Faiez Zannad, Jaison Jacob, Harry Hemingway, Michael R. Brown, Franco Giulianini, Anubha Mahajan, Xing Chen, Alexander Niessner, Peter Almgren, Daniel I. Swerdlow, Gunnar Engström, Lars Lind, Tõnu Esko, Tomasz Czuba, Anna Helgadottir, Harvey D. White, David J. Stott, Johan Ärnlöv, Lars Køber, Chim C. Lang, Krishna G. Aragam, Kent D. Taylor, Anders Mälarstig, Frederick K. Kamanu, Kenneth B. Margulies, Michelle L. O'Donoghue, Andrew D. Morris, Sahar Ghasemi, J. Wouter Jukema, Jessica van Setten, Abbas Dehghan, Guillaume Paré, Luca A. Lotta, Giorgio E. M. Melloni, Albert Henry, Bruce M. Psaty, Paul M. Ridker, David J. Carey, Marie-Pierre Dubé, John S. Gottdiener, Xiaosong Wang, Per H. Svensson, Xu Chen, Patrik K. E. Magnusson, Claudia Langenberg, Alexander Teumer, Vilmantas Giedraitis, Simon de Denus, Michael W. Nagle, Marcus Dörr, Thomas P. Cappola, André G. Uitterlinden, Michael Morley, Eliana Portilla-Fernandez, J. Gustav Smith, Abirami Veluchamy, Peter Weeke, Ify R. Mordi, Unnur Thorsteinsdottir, Naveed Sattar, Folkert W. Asselbergs, Daniel I. Chasman, Daníel F. Guðbjartsson, Jonathan H. Chung, Marcus E. Kleber, Raul Weiss, Christopher P. Nelson, Spiros Denaxas, Bing Yu, Simon P. R. Romaine, Nicholas A Marston, Anjali T. Owens, Cecilia M. Lindgren, John J.V. McMurray, Joshua D. Backman, Michael V. Holmes, Stella Trompet, Hilma Holm, Kerri L. Wiggins, Jian'an Luan, Stephan B. Felix, Yifan Yang, Jemma B. Wilk, Maryam Kavousi, Markus Perola, Christian T. Ruff, Jean-Claude Tardif, G Sveinbjörnsson, Samuel C. Dudley, Nicholas J. Wareham, Teemu J. Niiranen, Andrew P. Morris, Danny Tuckwell, Maris Teder-Laving, R. Thomas Lumbers, James P. Cook, Géraldine Asselin, William A. Chutkow, Winfried März, Steven A. Lubitz, John G.F. Cleland, Bill Kraus, Ramachandran S. Vasan, Christopher M. Haggerty, Olympe Chazara, Chris Finan, Heather L. Bloom, Hans-Peter Brunner-La Rocca, Francoise Fougerousse, Kenneth Rice, Craig L. Hyde, Graciela E. Delgado, Mark Chaffin, Marc S. Sabatine, Alanna C. Morrison, Kay-Tee Khaw, Kari Stefansson, Felix Vaura, Barry London, Isabella Kardys, Aroon D. Hingorani, Hongsheng Gui, Steen Stender, René Fouodjio, Mohsen Ghanbari, Pim van der Harst, Nicholas L. Smith, Karoline Kuchenbaecker, Adriaan A. Voors, Benoit Tyl
Publikováno v:
ESC Heart Failure
ESC Heart Failure, Wiley, 2021, ⟨10.1002/ehf2.13517⟩
2021, ' The genomics of heart failure : design and rationale of the HERMES consortium ', ESC heart failure . https://doi.org/10.1002/ehf2.13517
ESC Heart Failure. WILEY PERIODICALS, INC
ESC Heart Failure, 8(6), 5531-5541. WILEY PERIODICALS, INC
ESC heart failure, 8(6), 5531-5541. The Heart Failure Association of the European Society of Cardiology
ESC Heart Failure, 2021, ⟨10.1002/ehf2.13517⟩
Regeneron Genetics Center 2021, ' The genomics of heart failure : design and rationale of the HERMES consortium ', ESC heart failure, vol. 8, no. 6, pp. 5531-5541 . https://doi.org/10.1002/ehf2.13517
Esc heart failure, 8(6). John Wiley & Sons Inc.
Lumbers, R T, Shah, S, Lin, H, Czuba, T, Henry, A, Swerdlow, D I, Mälarstig, A, Andersson, C, Verweij, N, Holmes, M V, Ärnlöv, J, Svensson, P, Hemingway, H, Sallah, N, Almgren, P, Aragam, K G, Asselin, G, Backman, J D, Biggs, M L, Bloom, H L, Boersma, E, Brandimarto, J, Brown, M R, Brunner-La Rocca, H P, Carey, D J, Chaffin, M D, Chasman, D I, Chazara, O, Chen, X, Chen, X, Chung, J H, Chutkow, W, Cleland, J G F, Cook, J P, de Denus, S, Dehghan, A, Delgado, G E, Denaxas, S, Doney, A S, Dörr, M, Dudley, S C, Engström, G, Esko, T, Fatemifar, G, Felix, S B, Finan, C, Ford, I, Fougerousse, F, Fouodjio, R, Ghanbari, M, Ghasemi, S, Giedraitis, V, Giulianini, F, Gottdiener, J S, Gross, S, Guðbjartsson, D F, Gui, H, Gutmann, R, Haggerty, C M, van der Harst, P, Hedman, Å K, Helgadottir, A, Hillege, H, Hyde, C L, Jacob, J, Jukema, J W, Kamanu, F, Kardys, I, Kavousi, M, Khaw, K T, Kleber, M E, Køber, L, Koekemoer, A, Kraus, B, Kuchenbaecker, K, Langenberg, C, Lind, L, Lindgren, C M, London, B, Lotta, L A, Lovering, R C, Luan, J, Magnusson, P, Mahajan, A, Mann, D, Margulies, K B, Marston, N A, März, W, McMurray, J J V, Melander, O, Melloni, G, Mordi, I R, Morley, M P, Morris, A D, Morris, A P, Morrison, A C, Nagle, M W, Nelson, C P, Newton-Cheh, C, Niessner, A, Niiranen, T, Nowak, C, O'Donoghue, M L, Owens, A T, Palmer, C N A, Paré, G, Perola, M, Perreault, L P L, Portilla-Fernandez, E, Psaty, B M, Rice, K M, Ridker, P M, Romaine, S P R, Roselli, C, Rotter, J I, Ruff, C T, Sabatine, M S, Salo, P, Salomaa, V, van Setten, J, Shalaby, A A, Smelser, D T, Smith, N L, Stefansson, K, Stender, S, Stott, D J, Sveinbjörnsson, G, Tammesoo, M L, Tardif, J C, Taylor, K D, Teder-Laving, M, Teumer, A, Thorgeirsson, G, Thorsteinsdottir, U, Torp-Pedersen, C, Trompet, S, Tuckwell, D, Tyl, B, Uitterlinden, A G, Vaura, F, Veluchamy, A, Visscher, P M, Völker, U, Voors, A A, Wang, X, Wareham, N J, Weeke, P E, Weiss, R, White, H D, Wiggins, K L, Xing, H, Yang, J, Yang, Y, Yerges-Armstrong, L M, Yu, B, Zannad, F, Zhao, F, Regeneron Genetics Center, Wilk, J B, Holm, H, Sattar, N, Lubitz, S A, Lanfear, D E, Shah, S, Dunn, M E, Wells, Q S, Asselbergs, F W, Hingorani, A D, Dubé, M P, Samani, N J, Lang, C C, Cappola, T P, Ellinor, P T, Vasan, R S & Smith, J G 2021, ' The genomics of heart failure : design and rationale of the HERMES consortium ', ESC Heart Failure, vol. 8, no. 6, pp. 5531-5541 . https://doi.org/10.1002/ehf2.13517
ESC Heart Failure, Vol 8, Iss 6, Pp 5531-5541 (2021)
ESC Heart Failure, Wiley, 2021, ⟨10.1002/ehf2.13517⟩
2021, ' The genomics of heart failure : design and rationale of the HERMES consortium ', ESC heart failure . https://doi.org/10.1002/ehf2.13517
ESC Heart Failure. WILEY PERIODICALS, INC
ESC Heart Failure, 8(6), 5531-5541. WILEY PERIODICALS, INC
ESC heart failure, 8(6), 5531-5541. The Heart Failure Association of the European Society of Cardiology
ESC Heart Failure, 2021, ⟨10.1002/ehf2.13517⟩
Regeneron Genetics Center 2021, ' The genomics of heart failure : design and rationale of the HERMES consortium ', ESC heart failure, vol. 8, no. 6, pp. 5531-5541 . https://doi.org/10.1002/ehf2.13517
Esc heart failure, 8(6). John Wiley & Sons Inc.
Lumbers, R T, Shah, S, Lin, H, Czuba, T, Henry, A, Swerdlow, D I, Mälarstig, A, Andersson, C, Verweij, N, Holmes, M V, Ärnlöv, J, Svensson, P, Hemingway, H, Sallah, N, Almgren, P, Aragam, K G, Asselin, G, Backman, J D, Biggs, M L, Bloom, H L, Boersma, E, Brandimarto, J, Brown, M R, Brunner-La Rocca, H P, Carey, D J, Chaffin, M D, Chasman, D I, Chazara, O, Chen, X, Chen, X, Chung, J H, Chutkow, W, Cleland, J G F, Cook, J P, de Denus, S, Dehghan, A, Delgado, G E, Denaxas, S, Doney, A S, Dörr, M, Dudley, S C, Engström, G, Esko, T, Fatemifar, G, Felix, S B, Finan, C, Ford, I, Fougerousse, F, Fouodjio, R, Ghanbari, M, Ghasemi, S, Giedraitis, V, Giulianini, F, Gottdiener, J S, Gross, S, Guðbjartsson, D F, Gui, H, Gutmann, R, Haggerty, C M, van der Harst, P, Hedman, Å K, Helgadottir, A, Hillege, H, Hyde, C L, Jacob, J, Jukema, J W, Kamanu, F, Kardys, I, Kavousi, M, Khaw, K T, Kleber, M E, Køber, L, Koekemoer, A, Kraus, B, Kuchenbaecker, K, Langenberg, C, Lind, L, Lindgren, C M, London, B, Lotta, L A, Lovering, R C, Luan, J, Magnusson, P, Mahajan, A, Mann, D, Margulies, K B, Marston, N A, März, W, McMurray, J J V, Melander, O, Melloni, G, Mordi, I R, Morley, M P, Morris, A D, Morris, A P, Morrison, A C, Nagle, M W, Nelson, C P, Newton-Cheh, C, Niessner, A, Niiranen, T, Nowak, C, O'Donoghue, M L, Owens, A T, Palmer, C N A, Paré, G, Perola, M, Perreault, L P L, Portilla-Fernandez, E, Psaty, B M, Rice, K M, Ridker, P M, Romaine, S P R, Roselli, C, Rotter, J I, Ruff, C T, Sabatine, M S, Salo, P, Salomaa, V, van Setten, J, Shalaby, A A, Smelser, D T, Smith, N L, Stefansson, K, Stender, S, Stott, D J, Sveinbjörnsson, G, Tammesoo, M L, Tardif, J C, Taylor, K D, Teder-Laving, M, Teumer, A, Thorgeirsson, G, Thorsteinsdottir, U, Torp-Pedersen, C, Trompet, S, Tuckwell, D, Tyl, B, Uitterlinden, A G, Vaura, F, Veluchamy, A, Visscher, P M, Völker, U, Voors, A A, Wang, X, Wareham, N J, Weeke, P E, Weiss, R, White, H D, Wiggins, K L, Xing, H, Yang, J, Yang, Y, Yerges-Armstrong, L M, Yu, B, Zannad, F, Zhao, F, Regeneron Genetics Center, Wilk, J B, Holm, H, Sattar, N, Lubitz, S A, Lanfear, D E, Shah, S, Dunn, M E, Wells, Q S, Asselbergs, F W, Hingorani, A D, Dubé, M P, Samani, N J, Lang, C C, Cappola, T P, Ellinor, P T, Vasan, R S & Smith, J G 2021, ' The genomics of heart failure : design and rationale of the HERMES consortium ', ESC Heart Failure, vol. 8, no. 6, pp. 5531-5541 . https://doi.org/10.1002/ehf2.13517
ESC Heart Failure, Vol 8, Iss 6, Pp 5531-5541 (2021)
Aims The HERMES (HEart failure Molecular Epidemiology for Therapeutic targets) consortium aims to identify the genomic and molecular basis of heart failure.Methods and results The consortium currently includes 51 studies from 11 countries, including
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc41b40a62755853d7042fbc1dfd58a0
https://hal.univ-lorraine.fr/hal-03357134
https://hal.univ-lorraine.fr/hal-03357134
Autor:
Henrik Jensen, Lars Frost, Samuel Emil Schmidt, Bjarni J. Vilhjálmsson, Evald Høj Christiansen, Mette Nyegaard, Morten Bøttcher, Niels Ramsing Holm, Simon Winther, Kari Stefansson, Peter L. Møller, Hilma Holm, Hans Erik Bøtker, Jane Kirk Johansen, Louise Nissen, Morten Krogh Christiansen, Jelmer Westra, Daníel F. Guðbjartsson
Publikováno v:
Christiansen, M K, Winther, S, Nissen, L, Vilhjálmsson, B J, Frost, L, Johansen, J K, Møller, P L, Schmidt, S E, Westra, J, Holm, N R, Jensen, H K, Christiansen, E H, Guðbjartsson, D F, Hólm, H, Stefánsson, K, Bøtker, H E, Bøttcher, M & Nyegaard, M 2021, ' Polygenic Risk Score-Enhanced Risk Stratification of Coronary Artery Disease in Patients With Stable Chest Pain ', Circulation: Genomic and Precision Medicine, vol. 14, no. 3, pp. E003298 . https://doi.org/10.1161/CIRCGEN.120.003298
Christiansen, M K, Winther, S, Nissen, L, Vilhjálmsson, B J, Frost, L, Johansen, J K, Loof Møller, P, Schmidt, S E, Westra, J S, Holm, N R, Jensen, H K, Christiansen, E H, Guðbjartsson, D F, Hólm, H, Stefansson, K, Bøtker, H E, Bøttcher, M & Nyegaard, M 2021, ' Polygenic Risk Score-enhanced Risk Stratification of Coronary Artery Disease in Patients with Stable Chest Pain ', CIRCULATION-GENOMIC AND PRECISION MEDICINE, vol. 14, no. 3, e003298, pp. 323-330 . https://doi.org/10.1161/CIRCGEN.120.003298
Christiansen, M K, Winther, S, Nissen, L, Vilhjálmsson, B J, Frost, L, Johansen, J K, Loof Møller, P, Schmidt, S E, Westra, J S, Holm, N R, Jensen, H K, Christiansen, E H, Guðbjartsson, D F, Hólm, H, Stefansson, K, Bøtker, H E, Bøttcher, M & Nyegaard, M 2021, ' Polygenic Risk Score-enhanced Risk Stratification of Coronary Artery Disease in Patients with Stable Chest Pain ', Circulation. Genomic and precision medicine, vol. 14, no. 3, 003298, pp. 323-330 . https://doi.org/10.1161/CIRCGEN.120.003298
Christiansen, M K, Winther, S, Nissen, L, Vilhjálmsson, B J, Frost, L, Johansen, J K, Loof Møller, P, Schmidt, S E, Westra, J S, Holm, N R, Jensen, H K, Christiansen, E H, Guðbjartsson, D F, Hólm, H, Stefansson, K, Bøtker, H E, Bøttcher, M & Nyegaard, M 2021, ' Polygenic Risk Score-enhanced Risk Stratification of Coronary Artery Disease in Patients with Stable Chest Pain ', CIRCULATION-GENOMIC AND PRECISION MEDICINE, vol. 14, no. 3, e003298, pp. 323-330 . https://doi.org/10.1161/CIRCGEN.120.003298
Christiansen, M K, Winther, S, Nissen, L, Vilhjálmsson, B J, Frost, L, Johansen, J K, Loof Møller, P, Schmidt, S E, Westra, J S, Holm, N R, Jensen, H K, Christiansen, E H, Guðbjartsson, D F, Hólm, H, Stefansson, K, Bøtker, H E, Bøttcher, M & Nyegaard, M 2021, ' Polygenic Risk Score-enhanced Risk Stratification of Coronary Artery Disease in Patients with Stable Chest Pain ', Circulation. Genomic and precision medicine, vol. 14, no. 3, 003298, pp. 323-330 . https://doi.org/10.1161/CIRCGEN.120.003298
Background: Polygenic risk scores (PRSs) are associated with coronary artery disease (CAD), but the clinical potential of using PRSs at the single-patient level for risk stratification has yet to be established. We investigated whether adding a PRS t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59b1b136aefddb3cde98eb51375d7c63
https://pure.au.dk/portal/da/publications/polygenic-risk-scoreenhanced-risk-stratification-of-coronary-artery-disease-in-patients-with-stable-chest-pain(352e8a25-424d-4141-80a8-e09958e11655).html
https://pure.au.dk/portal/da/publications/polygenic-risk-scoreenhanced-risk-stratification-of-coronary-artery-disease-in-patients-with-stable-chest-pain(352e8a25-424d-4141-80a8-e09958e11655).html
Autor:
Cindy G. Boer, Timothy Kwok, Kristbjorg Gunnarsdottir, Tuan V. Nguyen, Jenny S.W. Lee, Seung-Hun Lee, Stefania Benonisdottir, Helgi Jonsson, Gunnar Sigurdsson, Unnur Styrkarsdottir, Kristinn Juliusson, Gudmundur L. Norddahl, Lan T. Ho-Pham, Jung Min Koh, Inger Byrjalsen, Daniel F. Gudbjartsson, Lilja Stefansdottir, Claus Christiansen, Unnur Thorsteinsdottir, Jason Leung, Thorvaldur Ingvarsson, Brynjolfur Mogensen, Eleftheria Zeggini, Olafur A. Stefansson, John Loughlin, Gisli Masson, Kari Stefansson, Arnaldur Gylfason, Lorraine Southam, Arna B Agustsdottir, Rafn Benediktsson, Fernando Rivadeneira, Gisli H. Halldorsson, Suzanne C. Ho, Hilma Holm, Katerina Trajanoska, Hakon Jonsson, Sigrun H. Lund, Joyce B. J. van Meurs, Florian Zink, Kristjan Norland, Nelson L.S. Tang, L. Stefan Lohmander, Erna V. Ivarsdottir, Gudmar Thorleifsson, Ingileif Jonsdottir, P. C. Leung, André G. Uitterlinden, John A. Eisman, Jean Woo, Patrick Sulem
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Nature Communications
Nature Communications, 10:Unsp 2054. Nature Publishing Group
Nat. Commun. 10:2054 (2019)
Nature Communications
Nature Communications, 10:Unsp 2054. Nature Publishing Group
Nat. Commun. 10:2054 (2019)
Publisher's version (útgefin grein).
Bone area is one measure of bone size that is easily derived from dual-energy X-ray absorptiometry (DXA) scans. In a GWA study of DXA bone area of the hip and lumbar spine (N ≥ 28,954), we find thirteen in
Bone area is one measure of bone size that is easily derived from dual-energy X-ray absorptiometry (DXA) scans. In a GWA study of DXA bone area of the hip and lumbar spine (N ≥ 28,954), we find thirteen in