Zobrazeno 1 - 10
of 15
pro vyhledávání: '"David G. Hoel"'
Publikováno v:
PLoS ONE, Vol 15, Iss 4, p e0232597 (2020)
PLoS ONE
PLoS ONE
The use of low doses of radium-224 (224Ra) chloride for the treatment of ankylosing spondylitis was stopped following the discovery that patients treated with it had a higher than control incidence of leukaemia and other cancers. This was so even tho
Publikováno v:
International Journal of Radiation Biology
Purpose: This review evaluates the role of dose rate on cell and molecular responses. It focuses on the influence of dose rate on key events in critical pathways in the development of cancer. This approach is similar to that used by the U.S. EPA and
Autor:
David G. Hoel
Publikováno v:
Health physics. 108(3)
Radiation cancer risk estimates have been based primarily on the atomic bomb survivor cohorts, which involve an acute exposure. To adjust for lower dose and continuous exposures, a dose and dose rate effectiveness factor (DDREF) is applied to the acu
Autor:
David G. Hoel
Publikováno v:
Annals of the New York Academy of Sciences. 1076:309-317
For more than 15 years the A-bomb survivor studies have shown increased noncancer mortality due to radiation exposures. The most prominent cause of this increase is circulatory disease mortality. Although the estimated relative risk is less than for
Publikováno v:
Urology. 66:587-592
Objectives To analyze the differences in the plasma levels of insulin-like growth factor-I (IGF-I), IGF-binding protein-3 (IGFBP-3), and their ratio between black and white men while controlling for factors that could confound the relationship betwee
Autor:
Paul J. Nietert, Susan E. Sutherland, Richard M. Silver, Rebecca G. Knapp, Janardan P. Pandey, David G. Hoel, Mustafa Dosemeci
Publikováno v:
Arthritis & Rheumatism. 41:1111-1118
Objective The primary objective was to determine whether occupational exposure to organic solvents is related to an increased risk of systemic sclerosis (SSc; scleroderma). Methods Occupational histories were obtained from 178 SSc patients and 200 co
Autor:
David G. Hoel
The basic purpose of this one year research grant was to extend the two stage clonal expansion model (TSCE) of carcinogenesis to exposures other than the usual single acute exposure. The two-stage clonal expansion model of carcinogenesis incorporates
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::067eacd57d6d7b39896f3e2d8ef7b686
https://doi.org/10.2172/1043283
https://doi.org/10.2172/1043283
Publikováno v:
Scopus-Elsevier
Determination of radiation protection guidelines for persons working with plutonium has been complicated by limited human data on the biological behavior and subsequent health effects from internally deposited plutonium. One solution has been the use
Publikováno v:
Public health nutrition. 10(1)
ObjectiveHigher levels of insulin-like growth factor-I (IGF-I) and lower levels of IGF binding protein-3 (IGFBP-3) have been associated with an increased risk of prostate cancer. Nutrition is known to partially regulate IGF levels and it is possible
Publikováno v:
American journal of industrial medicine. 48(5)
Background A program of medical evaluation for former Savannah River Site (SRS) workers at health effects due to exposures to hazardous or radioactive agents was conducted. Methods This study includes data from 1,368 participants aged 45 years or old