Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Christoph Kellendonk"'
Autor:
Jinrui Lyu, Christoph Kellendonk, Jonathan A. Javitch, Jie Zhang, Matthew S. McMurray, Stephanie C. Dulawa, Amanda C Welch
Publikováno v:
Molecular psychiatry, vol 26, iss 8
Molecular psychiatry
Molecular psychiatry
Anorexia nervosa (AN) is an eating disorder observed predominantly in women and girls that is characterized by a low body-mass index, hypophagia, and hyperactivity. Activity-based anorexia (ABA), which refers to the weight loss, hypophagia, and hyper
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b9c88ae8c76a26fa97e6936128f5e01
https://escholarship.org/uc/item/1pr1k584
https://escholarship.org/uc/item/1pr1k584
Autor:
Christoph Kellendonk, Andrea M. Sartori, Eleanor H. Simpson, Oliver Weinmann, Marie A. Labouesse, Ulrike Weber-Stadlbauer
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 115(41)
Dopaminergic signaling in the striatum, particularly at dopamine 2 receptors (D2R), has been a topic of active investigation in obesity research in the past decades. However, it still remains unclear whether variations in striatal D2Rs modulate the r
Autor:
Jose A. Morón, Michael C. Salling, Bo Feng, Jonathan A. Javitch, Christoph Kellendonk, Neil L. Harrison, Eduardo F. Gallo
Publikováno v:
Neuropsychopharmacology. 40:1609-1618
Brain imaging studies performed in humans have associated low striatal dopamine release and D2R binding with alcohol dependence. Conversely, high striatal D2R binding has been observed in unaffected members of alcoholic families suggesting that high
Autor:
M. Le Moal, Mohamed Jaber, Véronique Deroche-Gamonet, R. Izawa, Christoph Kellendonk, I. Sillaber, Pier Vincenzo Piazza, François Tronche
Publikováno v:
Neuroscience
Neuroscience, Elsevier-International Brain Research Organization, 2006, 137, pp.915-924
Neuroscience, Elsevier-International Brain Research Organization, 2006, 137, pp.915-924
Several findings suggest that glucocorticoid hormones influence the propensity of an individual to develop cocaine abuse. These hormones activate two related transcription factors, the glucocorticoid receptor and the mineralocorticoid receptor. We ha
Autor:
Wolfgang Schmid, Christoph Kellendonk, Christian Opherk, Andreas Schulze, François Tronche, Günther Schütz, Dirk Kohlmüller
Publikováno v:
Molecular Endocrinology. 18:1346-1353
Hepatic glucose production by gluconeogenesis is the main source of glucose during fasting and contributes significantly to hyperglycemia in diabetes mellitus. Accordingly, glucose metabolism is tightly controlled by a variety of hormones including i
Autor:
Lukas Schwake, Andreas Reimann, Günther Schütz, Wolfgang Schmid, Holger M. Reichardt, Hartmut Beug, Christoph Kellendonk, Katharina Stangl, Daniel Gau, Christian Opherk, Andreas Hoeflich, Richard Moriggl, François Tronche
Publikováno v:
Genes & Development. 18:492-497
Mice carrying a hepatocyte-specific inactivation of the glucorticoid receptor (GR) gene show a dramatic reduction in body size. Growth hormone signaling mediated by the Stat5 transcription factors is impaired. We show that Stat5 proteins physically i
Publikováno v:
Journal of Biological Chemistry. 277:28411-28417
STAT3 is rapidly induced during liver regeneration in an interleukin 6 (IL-6)-dependent fashion, and IL-6 is required for normal liver regeneration. We wanted to know whether STAT3 was also required for liver regeneration but disruption of the STAT3
Autor:
François Tronche, Peter Gass, Hans-Peter Lipp, Stefan Berger, Günther Schütz, Wolfgang Schmid, David P. Wolfer, Christoph Kellendonk, Oliver Kretz, Holger M. Reichardt
Publikováno v:
EMBO reports. 1:447-451
To dissect the effects of corticosteroids mediated by the mineralocorticoid (MR) and the glucocorticoid receptor (GR) in the central nervous system, we compared MR-/- mice, whose salt loss syndrome was corrected by exogenous NaCI administration, with
Autor:
Peter Gass, Oliver Kretz, Rudolf Bock, Christoph Kellendonk, Günther Schütz, Katrin Anlag, Rüdiger Klein, Paul C. Orban, François Tronche
Publikováno v:
Nature Genetics. 23:99-103
The glucocorticoid receptor (Gr, encoded by the gene Grl1) controls transcription of target genes both directly by interaction with DNA regulatory elements and indirectly by cross-talk with other transcription factors. In response to various stimuli,
Autor:
Jürgen Metz, Andreas Schober, Günther Schütz, Timothy J. Cole, Christoph Kellendonk, Karin Lindner, Konstantin Beier, Wolfgang Schmid, Barbara Brühl, Frauke Deimling, José E. García-Arrarás, José L. Roig-López, Francois Tronche, Klaus Unsicker, Kerstin Krieglstein, Susetta Finotto, Paula Monaghan
Publikováno v:
Development. 126:2935-2944
Molecular mechanisms underlying the generation of distinct cell phenotypes is a key issue in developmental biology. A major paradigm of determination of neural cell fate concerns the development of sympathetic neurones and neuroendocrine chromaffin c