Zobrazeno 1 - 10
of 3 419
pro vyhledávání: '"Byrne, BE"'
Autor:
Dan-Qin Sun, Fuqiang Yuan, Meng-Zhu Fu, Meng-Yang Zhong, Shi-Liang Zhang, Yan Lu, Giovanni Targher, Christopher D. Byrne, Ming-Hua Zheng, Wei-Jie Yuan
Publikováno v:
Molecular Metabolism, Vol 79, Iss , Pp 101841- (2024)
Objective: Activation of farnesoid X receptor (FXR), a bile acid nuclear receptor, may be implicated in the pathophysiology of diabetic nephropathy. We explored a possible role for FXR activation in preventing renal fibrosis in high fat diet (HFD)-fe
Externí odkaz:
https://doaj.org/article/f7bdadc31be8433692c488c59c9f0254
Autor:
George J. Xu, Matthew A. Loberg, Jean-Nicolas Gallant, Quanhu Sheng, Sheau-Chiann Chen, Brian D. Lehmann, Sophia M. Shaddy, Megan L. Tigue, Courtney J. Phifer, Li Wang, Mario W. Saab-Chalhoub, Lauren M. Dehan, Qiang Wei, Rui Chen, Bingshan Li, Christine Y. Kim, Donna C. Ferguson, James L. Netterville, Sarah L. Rohde, Carmen C. Solórzano, Lindsay A. Bischoff, Naira Baregamian, Aaron C. Shaver, Mitra Mehrad, Kim A. Ely, Daniel W. Byrne, Thomas P. Stricker, Barbara A. Murphy, Jennifer H. Choe, Luciane T. Kagohara, Elizabeth M. Jaffee, Eric C. Huang, Fei Ye, Ethan Lee, Vivian L. Weiss
Publikováno v:
Cell Genomics, Vol 3, Iss 10, Pp 100409- (2023)
Summary: Genomic and transcriptomic analysis has furthered our understanding of many tumors. Yet, thyroid cancer management is largely guided by staging and histology, with few molecular prognostic and treatment biomarkers. Here, we utilize a large c
Externí odkaz:
https://doaj.org/article/fc1b6ef5686b46cf86fe3857f3b602c5
Publikováno v:
Kidney and Dialysis, Vol 3, Iss 1, Pp 24-35 (2023)
(1) Background: Pain is a prevalent and debilitating symptom associated with kidney failure. However, the impact of pain on quality of life remains unclear. We aimed to identify the prevalence, severity and characteristics of people undertaking dialy
Externí odkaz:
https://doaj.org/article/32956a7b0c6543c29c72cb54649bc78a
Autor:
Sing-Young Chen, Martina Beretta, Ellen M. Olzomer, Divya P. Shah, Derek Y.H. Wong, Stephanie J. Alexopoulos, Isabella Aleksovska, Joseph M. Salamoun, Christopher J. Garcia, Blake J. Cochran, Kerry-Anne Rye, Greg C. Smith, Frances L. Byrne, Margaret J. Morris, Webster L. Santos, James Cantley, Kyle L. Hoehn
Publikováno v:
Molecular Metabolism, Vol 69, Iss , Pp 101684- (2023)
Objective: Calorie restriction is a first-line treatment for overweight individuals with metabolic impairments. However, few patients can adhere to long-term calorie restriction. An alternative approach to calorie restriction that also causes negativ
Externí odkaz:
https://doaj.org/article/e475640495114e8b9f51a21417a66099
Publikováno v:
Molecular Metabolism, Vol 66, Iss , Pp 101635- (2022)
Background: The dynamics of the cellular glycolysis pathway underpin cellular function and dysfunction, and therefore ultimately health, disease, diagnostic and therapeutic strategies. Evolving our understanding of this fundamental process and its dy
Externí odkaz:
https://doaj.org/article/695376d3355b4262b595ea876a3edc24
Autor:
Carla De Angelis, Alicia B. Byrne, Rebecca Morrow, Jinghua Feng, Thuong Ha, Paul Wang, Andreas W. Schreiber, Milena Babic, Ajay Taranath, Nick Manton, Sarah L. King-Smith, Quenten Schwarz, Peer Arts, Hamish S. Scott, Christopher Barnett
Publikováno v:
BMC Medical Genomics, Vol 14, Iss 1, Pp 1-7 (2021)
Abstract Background Periventricular nodular heterotopia (PNH) is a malformation of cortical development characterized by nodules of abnormally migrated neurons. The cause of posteriorly placed PNH is not well characterised and we present a case that
Externí odkaz:
https://doaj.org/article/0e4cc75ac4f7488c9bc12cc444e98502
Autor:
Begona Sanchez-Lechuga, Muhammad Saqlain, Nicholas Ng, Kevin Colclough, Conor Woods, Maria Byrne
Publikováno v:
BMC Medical Genetics, Vol 21, Iss 1, Pp 1-6 (2020)
Abstract Background Mutations in GATA6 are the most frequent cause of pancreatic agenesis. Most cases present with neonatal diabetes mellitus. Case presentation The case was a female born after an uncomplicated pregnancy and delivery in a non-consang
Externí odkaz:
https://doaj.org/article/a216ec83b00e45a5998260f7d42dc411
Publikováno v:
Molecular Metabolism, Vol 51, Iss , Pp 101222- (2021)
Background: Mitochondrial uncouplers are well-known for their ability to treat a myriad of metabolic diseases, including obesity and fatty liver diseases. However, for many years now, mitochondrial uncouplers have also been evaluated in diverse model
Externí odkaz:
https://doaj.org/article/da95f2d2be76415f934c0879c3b172d5
Autor:
Laurna McGovern, Robert A. Byrne
Publikováno v:
REC: Interventional Cardiology, Vol 4, Iss 1, Pp 4-5 (2022)
El uso de stents farmacoactivos (SFA) para el tratamiento de la estenosis de las arterias coronarias ha reducido notablemente la ne- cesidad de repetir la revascularización con respecto al uso de stents metálicos1. No obstante, como muchos paciente
Externí odkaz:
https://doaj.org/article/6720d0c4336e42f3986a55fdabf4eda7
Autor:
Lauren Y. Sandeman, Wan Xian Kang, Xuemin Wang, Kirk B. Jensen, Derick Wong, Tao Bo, Ling Gao, Jiajun Zhao, Christopher D. Byrne, Amanda J. Page, Christopher G. Proud
Publikováno v:
Molecular Metabolism, Vol 42, Iss , Pp 101054- (2020)
Objectives: Diet-driven obesity is increasingly widespread. Its consequences pose major challenges to human health and health care systems. There are MAP kinase-interacting kinases (MNKs) in mice, MNK1 and MNK2. Studies have demonstrated that mice la
Externí odkaz:
https://doaj.org/article/dbedafa795c94829810cffac9457bea6