Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Brian, Fulton-Howard"'
Autor:
John McNeil, Robert Sebra, Ingrid Winship, Paul A. James, Alan E. Renton, Brian Fulton-Howard, Elsdon Storey, Moeen Riaz, Joanne Ryan, Anne Murray, Alison Goate, Simon M. Laws, Colin L. Masters, Raj C. Shah, Paul Lacaze, Aamira Huq
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 13, Iss 1, Pp n/a-n/a (2021)
Introduction Diversity in cognition among apolipoprotein E (APOE) ε4 homozygotes can range from early‐onset Alzheimer's disease (AD) to a lifetime with no symptoms. Methods We evaluated a phenotypic extreme polygenic risk score (PRS) for AD betwee
Publikováno v:
Ann Neurol
Objective The purpose of this study was to infer causal relationships between 22 previously reported risk factors for Alzheimer's disease (AD) and the "AD phenome": AD, AD age of onset (AAOS), hippocampal volume, cortical surface area and thickness,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68954f0666e48aaadd7230e003f12fc8
https://europepmc.org/articles/PMC8088901/
https://europepmc.org/articles/PMC8088901/
Autor:
Paul F. O'Reilly, Gerard D. Schellenberg, Adam C. Naj, Li-San Wang, Shea J. Andrews, Richard Mayeux, Brian Fulton-Howard, Edoardo Marcora, Lindsay A. Farrer, Margaret A. Pericak-Vance, Alison Goate, Jonathan L. Haines
Background Potentially modifiable risk factors have been associated with Alzheimer’s disease (AD). However, the causality of these risk factors on AD is unclear. Using Mendelian randomization we evaluated the causal effect of potentially modifiable
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2645303225c55fad68393c147133176b
Autor:
Alison Goate, Christopher Patterson, Shea J. Andrews, Elias K. Michaelis, Alzheimer’s Disease Neuroimaging Initiative, Russell H. Swerdlow, Brian Fulton-Howard, Alden Gross, G. Peggy McFall, Judy Pa
Publikováno v:
Neurobiology of aging
We examined the associations between mitochondrial DNA haplogroups (MT-hg) and their interactions with a polygenic risk score based on nuclear-encoded mitochondrial genes (nMT-PRS) with risk of dementia and age of onset of dementia (AOO). Logistic re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4b16bce8a6db752849ee3766facb46b
https://doi.org/10.1101/654400
https://doi.org/10.1101/654400