Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Anna Ciotkowska"'
Autor:
Bingsheng Li, Beata Rutz, Christian G. Stief, Annabel Spek, Raphaela Waidelich, Ru Huang, Anna Ciotkowska, Yuhan Liu, Martin Hennenberg, Frank Strittmatter, Ruixiao Wang
Publikováno v:
Naunyn-Schmiedeberg's Archives of Pharmacology
Non-adrenergic prostate smooth muscle contractions may account for the limited effectiveness of α1-adrenoceptor antagonists, which are the first-line option for medical treatment of voiding symptoms suggestive of benign prostatic hyperplasia. In non
Autor:
Beata Rutz, Yiming Wang, Alexander Tamalunas, Christian G. Stief, Melanie Schott, Annika Herlemann, Christian Gratzke, Frank Strittmatter, Anna Ciotkowska, Patrick Keller, Martin Hennenberg, Raphaela Waidelich, Qingfeng Yu
Publikováno v:
American Journal of Physiology-Renal Physiology. 314:F47-F57
Prostate smooth muscle contraction is critical for etiology and treatment of male lower urinary tract symptoms (LUTS) and is promoted by small monomeric GTPases (RhoA and Rac). GTPases may be activated by guanosine nucleotide exchange factors (GEFs).
Autor:
Alexander Tamalunas, Annika Herlemann, Beata Rutz, Melanie Schott, Christian G. Stief, Anna Ciotkowska, Qingfeng Yu, Frank Strittmatter, Christian Gratzke, Patrick Keller, Martin Hennenberg, Yiming Wang
Publikováno v:
European Journal of Pharmacology. 803:39-47
Male lower urinary tract symptoms (LUTS) due to bladder outlet obstruction are characterized by abnormal smooth muscle contractions in the lower urinary tract. Alpha1-adrenoceptor antagonists may induce smooth muscle relaxation in the outflow region
Autor:
Christian Gratzke, Alice C. Acevedo, Martin Hennenberg, Frank Strittmatter, Anna Ciotkowska, Beata Rutz, Annika Herlemann, Christian G. Stief, Nicolas Wiemer, Qingfeng Yu, Yiming Wang, Aysenur Kan, Alexander Tamalunas
Publikováno v:
The Prostate. 77:697-707
BACKGROUND. Lower urinary tract symptoms (LUTS) suggestive of benign prostatic hyperplasia may be caused by prostate smooth muscle contraction. Although alpha(1)-blockers may improve symptoms by prostate smooth muscle relaxation, their efficacy is li
Autor:
Martin Hennenberg, Beata Rutz, Sophie Janich, Anna Ciotkowska, Christian Gratzke, Frank Strittmatter, Christian G. Stief, Chunxiao Liu, Alexander Tamalunas, Annika Herlemann, Yiming Wang, Raphaela Waidelich
Publikováno v:
British Journal of Pharmacology. 173:3342-3358
Background and Purpose In benign prostatic hyperplasia, increased prostate smooth muscle tone and prostate volume may contribute alone or together to urethral obstruction and voiding symptoms. Consequently, connections between smooth muscle tone and
Autor:
Anna Ciotkowska, Martin Hennenberg, Alexander Tamalunas, Beata Rutz, Christian G. Stief, Cora Sauckel, Christian Gratzke
Publikováno v:
Journal of Urology. 201
INTRODUCTION AND OBJECTIVES:Medical treatment in benign prostatic hyperplasia (BPH) includes reduction of prostate size to prevent disease progression, complications, and surgery, and also reductio...
Autor:
Raphaela Waidelich, Yiming Wang, Christian G. Stief, Beata Rutz, Paul Kuppermann, Christian Gratzke, Alexander Tamalunas, Qingfeng Yu, Annika Herlemann, Martin Hennenberg, Anna Ciotkowska
Publikováno v:
Journal of Urology. 201
INTRODUCTION AND OBJECTIVES:In benign prostatic hyperplasia, prostate smooth muscle contraction drives urethral obstruction, resulting in lower urinary tract symptoms. Inhibition of prostate contra...
Autor:
Beata Rutz, Frank Strittmatter, Christian G. Stief, Martin Hennenberg, Christian Gratzke, Bingsheng Li, Xiaolong Wang, Chunxiao Liu, Annika Herlemann, Yiming Wang, Alexander Tamalunas, Christian Sterr, Qingfeng Yu, Anna Ciotkowska, Raphaela Waidelich
Publikováno v:
Oxidative Medicine and Cellular Longevity, Vol 2019 (2019)
Oxidative Medicine and Cellular Longevity
Oxidative Medicine and Cellular Longevity
Epidemiologic studies revealed a context between lower urinary tract symptoms (LUTS) suggestive of benign prostatic hyperplasia (BPH) and metabolic syndrome. However, molecular mechanisms underlying this relationship are largely unknown. Prostate enl
Autor:
Annika Herlemann, Christian Gratzke, Martin Hennenberg, Christian G. Stief, Aysenur Kan, Anna Ciotkowska, Melanie Schott, Beata Rutz, Alexander Tamalunas, Qingfeng Yu, Patrick Keller, Frank Strittmatter, Yiming Wang
Publikováno v:
The Prostate. 76:1364-1374
BACKGROUND The phosphodiesterase (PDE) 5 inhibitor tadalafil is available for treatment of male lower urinary tract symptoms (LUTS), while the role of other PDE isoforms for prostate smooth muscle tone is still unknown. Here, we examined effects of t
Autor:
R. Wang, Anna Ciotkowska, Alexander Tamalunas, Xiaolong Wang, B. Rutz, Qingfeng Yu, Christian G. Stief, Raphaela Waidelich, B. Li, M. Hennenberg
Publikováno v:
European Urology Open Science, Vol 19, Iss, Pp e983-(2020)