Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Andres J. Klein-Szanto"'
Publikováno v:
Biochemical Pharmacology. 164:336-341
Hypercholesterolemia represents a leading cause in the development of atherosclerotic plaques, increasing the risk for ACVS. It actually counts as a major cause of cardiovascular disease etiopathogenesis. The causes of hypercholesterolemia are multif
Autor:
Kelly A. Whelan, Benjamin J. Wilkins, Okan U. Elci, Evan S. Dellon, Gary W. Falk, Jonathan Gross, Bridget Godwin, Andres J. Klein-Szanto, Hiroshi Nakagawa, Jonathan M. Spergel, Maureen DeMarshall, Amanda B. Muir, Medha Sharma, Alain Benitez, Chris A. Liacouras
Publikováno v:
Clin Gastroenterol Hepatol
Background & Aims Although eosinophil count is the standard used to monitor disease activity in patients with eosinophilic esophagitis (EoE), there are often disparities between patient-reported symptoms and eosinophil counts. We examined the prevale
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9caf01105763de1fa0d9d57e16578429
https://europepmc.org/articles/PMC7058491/
https://europepmc.org/articles/PMC7058491/
Autor:
Andres J. Klein-Szanto, Javier S. Castresana, Daniel E. Bassi, Gary Thomas, Ricardo Lopez de Cicco, Javier Mercapide
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 25(8)
Purpose: Astrocytoma arises in the central nervous system as a tumorof great lethality, in part because of the invasive potential of the neoplastic cells that are able to release extracellular matrix-degrading enzymes. Furin convertase activates seve
Publikováno v:
Molecular Carcinogenesis. 54:1122-1131
PACE4 (PCSK6) is a proprotein convertase (PC) capable of processing numerous substrates involved in tumor growth, invasion, and metastasis. Because of the human relevancy of the tobacco-associated carcinogen benzo[a]pyrene (B(a)P) we investigated whe
Autor:
Miriam N. Lango, Brian L. Egleston, Carolyn Y. Fang, Jamie L. Studts, Margret B. Einarson, Dana H. Bovbjerg, John A. Ridge, Andres J. Klein-Szanto, Barbara Burtness
Publikováno v:
Head & Neck. 36:1113-1119
Background Psychosocial functioning is associated with vascular endothelial growth factor (VEGF) in various patient populations. This study examined whether psychosocial functioning in patients with head and neck squamous cell carcinoma (HNSCC) is as
Autor:
Xiang Xi Xu, Andrew K. Godwin, Andres J. Klein-Szanto, Ying Wang, Toni M. Yeasky, Elizabeth R. Smith, Thomas C. Hamilton, Robert B. Moore, Parvin Ganjei-Azar, Kathy Q. Cai
Publikováno v:
Molecular and cellular biology. 36(18)
We modeled the etiology of postmenopausal biology on ovarian cancer risk using germ cell-deficient white-spotting variant (Wv) mice, incorporating oncogenic mutations. Ovarian cancer incidence is highest in peri- and postmenopausal women, and epidemi
Autor:
Ekaterina G. Shatalova, Andres J. Klein-Szanto, Edna Cukierman, Karthik Devarajan, Margie L. Clapper
Publikováno v:
Cancer Prevention Research. 4:107-115
Squamous cell carcinoma of the head and neck (HNSCC) is the sixth most common type of cancer in the United States. The goal of this study was to evaluate the contribution of estrogens to the development of HNSCCs. Various cell lines derived from earl
Autor:
Jonathan Chernoff, Karthik Devarajan, Stephen A. Boorjian, Yan Zhou, Andres J. Klein-Szanto, Igor Makhlin, Christopher J. Long, Jiaru Zhang, Min Huang
Publikováno v:
BJU International. 108:E84-E90
OBJECTIVE To investigate whether mammalian target of rapamycin (mTOR) inhibition by rapamycin is therapeutically efficacious in combination with cisplatin for bladder cancer. MATERIALS AND METHODS Using a panel of human urothelial carcinoma cell line
Autor:
Masami Hayashi, Deborah A. Altomare, Kimihiko Ito, Kenjiro Sawada, Yoshito Terai, Joseph R. Testa, Robert A. Burger, Chiaki Kawase, Andres J. Klein-Szanto, Tadashi Kimura, Yukihiro Nishio, Seiji Mabuchi, Masahide Ohmichi, Ken-ichirou Morishige
Publikováno v:
Molecular Cancer Therapeutics. 9:2411-2422
This study examines the role of vascular endothelial growth factor (VEGF) as a therapeutic target in clear cell carcinoma (CCC) of the ovary, which has been regarded as a chemoresistant histologic subtype. Immunohistochemical analysis using tissue mi
Autor:
Katherine A. High, Richard C. Austin, Jirko Kühnisch, Alexander Schlachterman, Michael Slifker, Šárka Lhoták, Aladdin Mustafa, Warren D. Kruger, Sapna Gupta, Andres J. Klein-Szanto
Publikováno v:
The FASEB Journal. 23:883-893
Untreated cystathionine β-synthase (CBS) deficiency in humans is characterized by extremely elevated plasma total homocysteine (tHcy>200 μM), with thrombosis as the major cause of morbidity. Treatment with vitamins and diet leads to a dramatic redu