Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Crispin A"'
Autor:
Andreas Schalhorn, Clemens Giessen-Jung, Dominik Paul Modest, Alexander Crispin, J. C. von Einem, Ursula Vehling-Kaiser, Jens Neumann, Arndt Stahler, Martina Stauch, Volker Heinemann, T. Kirchner, Sebastian Stintzing, Swantje Held, Andreas Jung, D. Quietzsch, L. Fischer von Weikersthal, Julian Walter Holch
Publikováno v:
International Journal of Cancer. 138:739-746
Our aim was to investigate the impact of EREG and AREG mRNA expression (by RT-qPCR) in patients with metastatic colorectal cancer (mCRC). In addition, epidermal growth factor receptor (EGFR) expression (by immunohistochemistry) as well as RAS-and PIK
Publikováno v:
Infectious Agents and Cancer, Vol 11, Iss 1, Pp 1-11 (2016)
Infectious Agents and Cancer
Infectious Agents and Cancer
Background Tanzania, like other low-income countries, has an increasing cancer burden that remains underestimated. Infection-associated malignancies, particularly HIV-infection, represent a great proportion of cancer burden in Tanzania and throughout
Autor:
Navin Mani, Johannes H.A.M. Kaanders, Amanda Eustace, Jarrod J Homer, Joely J Irlam, Janet Taylor, Peter Hoskin, Paul N. Span, Guy N J Betts, Catharine M L West, Helen Denley, Ana M. Rojas, Francesca M. Buffa, Adrian L. Harris, Crispin J. Miller
Publikováno v:
Clinical Cancer Research; Vol 19
Clinical Cancer Research
Clinical Cancer Research, 19, 17, pp. 4879-4888
Clinical Cancer Research, 19, 4879-4888
Clinical Cancer Research
Clinical Cancer Research, 19, 17, pp. 4879-4888
Clinical Cancer Research, 19, 4879-4888
Purpose: Tumor hypoxia is associated with a poor prognosis, hypoxia modification improves outcome, and hypoxic status predicts benefit from treatment. Yet, there is no universal measure of clinical hypoxia. The aim of this study was to investigate wh
Autor:
Helen R Valentine, Guy N J Betts, Amanda Eustace, Carla S. Möller-Levet, Crispin J. Miller, Shalini Patiar, Francesca M. Buffa, Jarrod J Homer, Catharine M L West, Gillian Hall, Anassuya Ramachandran, Joely J Irlam, Ashirwad Merve, Adrian L. Harris
Background and purpose: Tumour hypoxia is associated with a poor prognosis in head and neck squamous cell carcinoma (HNSCC), however there is no accepted method for assessing hypoxia clinically. We aimed to conduct a technical validation of a hypoxia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62860c443968aac6685d59eebb387d92
https://doi.org/10.1016/j.ejca.2012.07.028
https://doi.org/10.1016/j.ejca.2012.07.028
Autor:
Helen Turley, Priyamal Silva, B.T. Musgrove, Philip Sloan, Crispin J. Miller, Graham J. Cox, Helen R Valentine, Nicholas J Slevin, Ketan A. Shah, Jarrod J Homer, Francesca M. Buffa, Catharine M L West, Rogan Corbridge, Patricia M Price, Stuart Winter, Adrian L. Harris
Affymetrix U133plus2 GeneChips were used to profile 59 head and neck squamous cell cancers. A hypoxia metagene was obtained by analysis of genes whose in vivo expression clustered with the expression of 10 well-known hypoxia-regulated genes (e.g., CA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d6dceb7bacdfd65700d1f2ef75b92af
https://doi.org/10.1158/0008-5472.can-06-3322
https://doi.org/10.1158/0008-5472.can-06-3322
Autor:
Christopher J. Morrow, Ged Brady, Hui Sun Leong, Karen Morris, Mathew Carter, Jenny Antonello, Yaoyong Li, Louise Carter, Cassandra L Hodgkinson, Christopher Smowton, Crispin J. Miller, Andrew Hughes, Caroline Dive, Dominic G. Rothwell, Fabiola Fernandez-Gutierrez, Deborah J. Burt, Fiona H Blackhall, Lynsey Priest, Barbara Mesquita
Publikováno v:
Nature medicine. 23(1)
In most patients with small-cell lung cancer (SCLC)-a metastatic, aggressive disease-the condition is initially chemosensitive but then relapses with acquired chemoresistance. In a minority of patients, however, relapse occurs within 3 months of init
Autor:
Matthew G Krebs, John Brognard, Robert Metcalf, Emma Howard, Carla Siswick, Helen Eaton, Hui Sun Leong, Sakshi Gulati, Jaseela Chiramel, Crispin J. Miller, Marianna Christodolou, N. J. T. Smith, Natalie Cook, Sreeja Aruketty, Andrew L. Wallace, Dominic G. Rothwell, Fiona C Thistlethwaite, Andrew Hughes, Caroline Dive, Mahmood Ayub, Joanne Dransfield, Emma Dean, Ged Brady, Andrew M Hudson, Richard Marais, Louise Carter
Publikováno v:
European Journal of Surgical Oncology (EJSO). 42:S244-S245
Publikováno v:
Journal of Pharmacy and Pharmacology. 60:1667-1672
A few studies have reported a relationship between leptin induced by brain injury and healing of bone tissue. Our objective was to measure serum and callus leptin expression within the setting of fracture and traumatic brain injury (TBI). Sixty-four
Autor:
Peter F. M. Choong, Crispin R. Dass
Publikováno v:
Journal of Pharmacy and Pharmacology. 60:405-413
Gene therapy, an applied form of biotechnology, relies on the delivery of foreign DNA into cells. More than 50% of all reported clinical trials for gene therapy are for cancer, though only a scant number for osteosarcoma. Osteosarcoma is a neoplasm a
Publikováno v:
Journal of Cancer Research and Clinical Oncology. 133:193-198
Osteosarcoma cells derived from patients have been isolated and subsequently cultured for the past 35 years. To date though, there have been no major break-throughs in the development of a model for osteosarcoma that uses orthotopic implantation of h