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Publikováno v:
Modern Pathology. 35:495-505
Breast neuroendocrine neoplasms (NENs) constitute a rare histologic subtype that includes both neuroendocrine tumors (NETs) and neuroendocrine carcinomas (NECs). In this study, we aimed to gain insight into the clinical and molecular characteristics
Autor:
Yoon Ji Choi, Jae Sook Sung, Soohyeon Lee, Seungtaek Lim, Mi Sun Ahn, Yeul Hong Kim, Jung Yoon Choi, Youngwoo Lee, Hee-Joon Chung, Hye Sook Kim, Yu Jung Kim, Jong Won Lee, Eun Joo Kang, Young Saing Kim, Won Jin Chang, Ah Reum Lim, Taekyu Lim, Ju Won Kim, Sung Shim Cho, Jang Ho Cho, Sang Won Shin, Kyong Hwa Park, Ji Hyun Park, Jung Sun Kim
Publikováno v:
Cancer Research and Treatment : Official Journal of Korean Cancer Association
Purpose K-MASTER project is a Korean national precision medicine platform that screened actionable mutations by analyzing next-generation sequencing (NGS) of solid tumor patients. We compared gene analyses between NGS panel from the K-MASTER project
Autor:
Jiro Fujita, Daijiro Nabeya, Akiko Maeda, Shuhei Yokoyama, Tomoo Kishaba, Soichi Shiiki, Hiroaki Nagano, Takeshi Kinjo, Shunichi Takakura
Publikováno v:
Internal Medicine. 61:111-114
We herein report four patients with community-acquired respiratory virus (CRV) infection. Although they had no history of contact with any individual with coronavirus disease 2019 (COVID-19), they were suspected of having COVID-19 based on findings o
Publikováno v:
Mediators of Inflammation
Mediators of Inflammation, Vol 2021 (2021)
Mediators of Inflammation, Vol 2021 (2021)
The Tn antigen, an N-acetylgalactosamine structure linked to serine or threonine, has been shown to induce high-specificity, high-affinity anti-Tn antibodies in mice. Maternal immunization with the Tn vaccine increases serum anti-Tn antibody titers a
Autor:
Chang-Tsu Yuan, Sze-Hwei Lee, Wen-Chien Chou, Chien-Chin Lin, Hwei-Fang Tien, Jia-Hao Liu, Ko-Ping Chang, Jih-Lu Tang, Chao-Hong Wei, Hsin-An Hou, Cheng-Hong Tsai
Publikováno v:
The Journal of Pathology: Clinical Research
The Journal of Pathology: Clinical Research, Vol 8, Iss 1, Pp 78-87 (2022)
The Journal of Pathology: Clinical Research, Vol 8, Iss 1, Pp 78-87 (2022)
Myeloproliferative neoplasms (MPNs) are characterized by upregulation of proinflammatory cytokines and immune dysregulation, which provide a reasonable basis for immunotherapy in patients. Megakaryocytes are crucial in the pathogenesis of primary mye
Autor:
V. M. Bondarenko, O. H. Ivanko
Publikováno v:
Patologìâ, Vol 18, Iss 2, Pp 196-202 (2021)
Aim. To use the cluster analysis of clinical and laboratory data, characteristic to children aged 6 to 24 months with acute diarrhea, in demonstrating the signs of infectious or functional intestinal disorders. Materials and methods. 56 children admi
Autor:
David Meredith, Sanda Alexandrescu, Patrick Y. Wen, Keith L. Ligon, Jared T. Ahrendsen, Kee Kiat Yeo, Shakti H. Ramkissoon, Seth Malinowski, Matthew Torre, David A. Reardon, Jason L. Hornick
Publikováno v:
Modern Pathology. 34:1236-1244
The 2016 WHO classifies IDH-mutant gliomas into oligodendroglioma or diffuse astrocytoma based on co-occurring genetic events. Recent literature addresses the concept of stratifying IDH-mutant gliomas based on prognostically significant molecular eve
Autor:
Kai Bachmann, Tarik Ghadban, Ronald Simon, Nathaniel Melling, Claudia Hube-Magg, Eugen Bellon, Michael Tachezy, Katharina Grupp, Jakob R. Izbicki, Guido Sauter
Publikováno v:
Journal of Cancer Research and Clinical Oncology
Introduction Lysophosphatidylcholine acyltransferase 1 (LPCAT1) has repeatedly been suggested to be associated with tumorigenesis. To evaluate the role of LPCAT1 in esophageal cancer, LPCAT1 immunostaining was analyzed on a tissue microarray containi
Autor:
Sung Chul Jung, Sungjin Chung, Ho-Shik Kim, Eun Sil Koh, Yura Chae, Songhee Oh, Mina Son, Seok Joon Shin, Cheol Whee Park, Yong Kyun Kim
Publikováno v:
Kidney Research and Clinical Practice, Vol 40, Iss 2, Pp 208-219 (2021)
Kidney Research and Clinical Practice
Kidney Research and Clinical Practice
Background: Fabry disease is a rare X-linked genetic lysosomal disorder caused by mutations in the GLA gene encoding alpha-galac tosidase A. Despite some data showing that profibrotic and proinflammatory cytokines and oxidative stress could be involv
Autor:
P. H. Pantielieiev, I. S. Haidash
Publikováno v:
Patologìâ, Vol 18, Iss 1, Pp 50-57 (2021)
Aim. The aim of the study was to study changes in matrix metalloproteinases and their tissue inhibitors in the tears and blood serum of patients with herpetic keratoconjunctivitis under the influence of antiherpetic antibodies and nimesulide. Materia