Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Jonathan D. Edgeworth"'
Publikováno v:
Journal of Hospital Infection. 106:419-428
Summary Introduction Extended-spectrum beta-lactamase-producing Enterobacterales (ESBL-E) and other multi-drug-resistant Gram-negative bacteria (MDR-GNB) have disseminated globally since their discovery in the late 20th century. Various infection pre
Autor:
Clemens Gutmann, Adam Nabeebaccus, Adrian Hayday, Matthew Fish, Kevin O'Gallagher, Francesca Trovato, Salvatore Napoli, Georg Auzinger, Lukas E Schmidt, Mark J. W. McPhail, Matthias Hackl, Andreas B. Diendorfer, Sean A. Burnap, Salma F Mujib, Blair Merrick, Barnaby Sanderson, Ajay M. Shah, Ludwig Traby, Christian Cassel, Roman Roy, Manuel Mayr, Manu Shankar-Hari, Jonathan D. Edgeworth, Konstantinos Theofilatos, Sabine Eichinger, Kseniya Khamina
Publikováno v:
Gutmann, C, Khamina, K, Theofilatos, K, Diendorfer, A B, Burnap, S A, Nabeebaccus, A, Fish, M, McPhail, M J W, O'Gallagher, K, Schmidt, L E, Cassel, C, Auzinger, G, Napoli, S, Mujib, S F, Trovato, F, Sanderson, B, Merrick, B, Roy, R, Edgeworth, J D, Shah, A M, Hayday, A C, Traby, L, Hackl, M, Eichinger, S, Shankar-Hari, M & Mayr, M 2022, ' Association of cardiometabolic microRNAs with COVID-19 severity and mortality ', Cardiovascular Research, vol. 118, no. 2, pp. 461-474 . https://doi.org/10.1093/cvr/cvab338
Cardiovascular research
Cardiovascular Research
Gutmann, C, Khamina, K, Theofilatos, K, Diendorfer, A B, Burnap, S A, Nabeebaccus, A, Fish, M, McPhail, M J W, O'Gallagher, K, Schmidt, L E, Cassel, C, Auzinger, G, Napoli, S, Mujib, S F, Trovato, F, Sanderson, B, Merrick, B, Roy, R, Edgeworth, J D, Shah, A M, Hayday, A C, Traby, L, Hackl, M, Eichinger, S, Shankar-Hari, M & Mayr, M 2021, ' Association of cardiometabolic microRNAs with COVID-19 severity and mortality ', Cardiovascular Research . https://doi.org/10.1093/cvr/cvab338
Cardiovascular research
Cardiovascular Research
Gutmann, C, Khamina, K, Theofilatos, K, Diendorfer, A B, Burnap, S A, Nabeebaccus, A, Fish, M, McPhail, M J W, O'Gallagher, K, Schmidt, L E, Cassel, C, Auzinger, G, Napoli, S, Mujib, S F, Trovato, F, Sanderson, B, Merrick, B, Roy, R, Edgeworth, J D, Shah, A M, Hayday, A C, Traby, L, Hackl, M, Eichinger, S, Shankar-Hari, M & Mayr, M 2021, ' Association of cardiometabolic microRNAs with COVID-19 severity and mortality ', Cardiovascular Research . https://doi.org/10.1093/cvr/cvab338
Aims Coronavirus disease 2019 (COVID-19) can lead to multiorgan damage. MicroRNAs (miRNAs) in blood reflect cell activation and tissue injury. We aimed to determine the association of circulating miRNAs with COVID-19 severity and 28 day intensive car
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bee058733d1ff5ea0db0e48b3863079e
Autor:
William Newsholme, Andrea Telatin, Christopher Alder, Andrew J. Page, Luke B Snell, Nicholas A Barrett, Ula Mahadeva, Anna Green, Amita Patel, Themoula Charalampous, Tom G. S. Williams, Jonathan D. Edgeworth, Rahul Batra, Carolyn J Hemsley, Luigi Camporota, Christopher I S Meadows, Lisa Bryan, Duncan Wyncoll, Adela Alcolea-Medina, Justin O'Grady, Sara E Boyd, Penelope R. Cliff
Publikováno v:
Genome Medicine
Genome Medicine, Vol 13, Iss 1, Pp 1-16 (2021)
Genome Medicine, Vol 13, Iss 1, Pp 1-16 (2021)
Background Clinical metagenomics (CMg) has the potential to be translated from a research tool into routine service to improve antimicrobial treatment and infection control decisions. The SARS-CoV-2 pandemic provides added impetus to realise these be
Autor:
Rahul Batra, Julie V. Robotham, Jonathan D. Edgeworth, Stijn Vansteelandt, Timo Smieszek, Koen B. Pouwels
Publikováno v:
Journal of Hospital Infection, 99(1), 42-47. W B SAUNDERS CO LTD
BACKGROUND: Studies often ignore time-varying confounding or may use inappropriate methodology to adjust for time-varying confounding.AIM: To estimate the effect of intensive care unit (ICU)-acquired bacteraemia on ICU mortality and discharge using a
Publikováno v:
Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
Background Methicillin-resistant Staphylococcus aureus (MRSA) and Clostridium difficile infections declined across the UK National Health Service in the decade that followed implementation of an infection control campaign. The national impact on inte
Publikováno v:
Expert Review of Anti-infective Therapy. :1-9
Effective antimicrobial stewardship is an increasingly important concern for healthcare providers globally. Antibiotics are frequently prescribed for patients who develop sepsis in the intensive care unit and traditionally courses are prolonged, with
Autor:
Timo Smieszek, Stijn Vansteelandt, Koen B. Pouwels, E. van Kleef, Rahul Batra, Julie V. Robotham, Jonathan D. Edgeworth
Publikováno v:
Journal of Hospital Infection, 96(1), 23-28. W B SAUNDERS CO LTD
BACKGROUND: Conflicting results have been found regarding outcomes of intensive care unit (ICU)-acquired Enterobacteriaceae bacteraemia and the potentially modifying effect of appropriate empiric antibiotic therapy.AIM: To evaluate these associations
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48891f076812453b5a2fcc0aee46e0e7
https://researchonline.lshtm.ac.uk/id/eprint/4651070/1/Does-appropriate-empiric-antibiotic-therapy-modify-ICU-acquired-Enterobacteriaceae-bacteraemia.pdf
https://researchonline.lshtm.ac.uk/id/eprint/4651070/1/Does-appropriate-empiric-antibiotic-therapy-modify-ICU-acquired-Enterobacteriaceae-bacteraemia.pdf
Clustering of Antimicrobial Resistance Outbreaks Across Bacterial Species in the Intensive Care Unit
Autor:
AP Cox, A.L.M. Vlek, Olga Tosas Auguet, Ben S. Cooper, Jonathan D. Edgeworth, Theodore Kypraios
Publikováno v:
Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
Outbreaks of bacterial species occur for the majority of bacteria commonly identified in the intensive care unit. This study provides evidence for frequent temporal clustering of resistance outbreaks consistent with interspecies transmission of resis
Autor:
H Muskett, Fire Study Investigators, Jason Shahin, Rosemary Ann Barnes, Christopher C. Kibbler, Neil Soni, Sharmistha Biswas, Sheila Harvey, Jonathan D. Edgeworth, K Patel, Kathryn M Rowan, David A Harrison, Elizabeth Allen
Publikováno v:
Critical Care
BACKGROUND: Given the predominance of invasive fungal disease (IFD) amongst the non-immunocompromised adult critically ill population, the potential benefit of antifungal prophylaxis and the lack of generalisable tools to identify high risk patients,
Autor:
Manu Shankar-Hari, Catherine McKenzie, Jonathan D. Edgeworth, Duncan Wyncoll, Irina Chis Ster
Publikováno v:
The Journal of antimicrobial chemotherapy. 69(6)
OBJECTIVES To determine long-term adherence to a 5 day antibiotic course guideline for treating intensive care unit (ICU)-acquired Gram-negative bacteria (GNB) infections. METHODS Descriptive analysis of patient-level data on all GNB-active antibioti