Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Christoph M. Hammers"'
Autor:
Inke R. König, Christian D. Sadik, Ana Luiza Lima, Enno Schmidt, A. Kleinheinz, A. Weidinger, Christoph M. Hammers, Damian Gola, A. von Georg, Franziska Hübner, Stefan W. Schneider, Alexander Katalinic, Maike M. Holtsche, N. van Beek, Regine Gläser, Detlef Zillikens
Publikováno v:
Journal of the European Academy of Dermatology and Venereology. 35:1197-1202
Background Autoimmune bullous diseases (AIBD) are rare disorders characterized by autoantibody formation against components of adhesion molecules; in pemphigoid diseases (PD), these are proteins of hemidesmosomes and basement membrane, important for
Autor:
Arnon D. Cohen, Shira Zelber-Sagi, Christoph M. Hammers, Virginia A. Jones, Khalaf Kridin, Kyle T. Amber, Payal M. Patel, Giovanni Damiani
Publikováno v:
Immunologic Research
Data regarding the association between pemphigus and rheumatoid arthritis (RA) is inconclusive and yet to be firmly established. In the current study, we aimed to evaluate the risk of developing RA during the course of pemphigus. A large-scale popula
Autor:
Nick Feldmann, Christoph M. Hammers, Shirin Emtenani, Enno Schmidt, Imke A. K. Burmester, Sarah Flaswinkel, Khalaf Kridin, Nina van Beek, Mayumi Kamaguchi, Clara-Sophie Thies, Valéria Bumiller-Bini, Ralf Ludwig, Detlef Zillikens, Jennifer E. Hundt, Anika Kasprick
Publikováno v:
British Journal of Pharmacology
Background and purpose Pemphigus is caused by autoantibodies against desmoglein (Dsg) 1, Dsg3 and/or non-Dsg antigens. Pemphigus vulgaris (PV) is the most common manifestation of pemphigus, with painful erosions on mucous membranes. In most cases, bl
Autor:
Saeedeh Ghorbanalipoor, Sarah Mayer-Hain, Takashi Hashimoto, Christian Probst, Cord Sunderkötter, Christoph M. Hammers, L. Komorowski, Khalaf Kridin, Hendri H. Pas, Kaja Męcińska-Jundziłł, Andreas Recke, Enno Schmidt, Shirin Emtenani, Rafał Czajkowski, Detlef Zillikens, Jennifer E. Hundt, Stefan W. Schneider, Ralf Ludwig
Publikováno v:
Journal of Investigative Dermatology, 141(12), 2820-2828. ELSEVIER SCIENCE INC
Pathomechanisms in IgA pemphigus are assumed to rely on Fc-dependent cellular activation by antigen-specific IgA autoantibodies; however, models for the disease and more detailed pathophysiologic data are lacking. In this study, we aimed to establish
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4f929ad4f07d6dd7b5a513ba88d4b95
https://research.rug.nl/en/publications/61d82c45-3e0e-4464-9a6e-37a811162879
https://research.rug.nl/en/publications/61d82c45-3e0e-4464-9a6e-37a811162879
Autor:
P. Bernard, Miklós Sárdy, Van Beek N, Pascal Joly, Franziska Hübner, Claudia Günther, Snejina Vassileva, Claudia Pföhler, Orsolya N. Horváth, Kossara Drenovska, Márton D, von Georg A, A. Patsatsi, Meriem Belheouane, Sandrine Benoit, Britt Marie Hermes, Saleh M. Ibrahim, Detlef Zillikens, Christoph M. Hammers, Huilaja L, Christian D. Sadik, Sascha Gerdes, Linnemann B, Enno Schmidt, John F. Baines, Bernhard Homey, Maria-Elisabeth Goebeler, Maike M. Holtsche, Regine Gläser
IntroductionBullous pemphigoid (BP) is the most common autoimmune blistering disease. It predominately afflicts the elderly and is significantly associated with increased mortality. The observation of age-dependent changes in the skin microbiota as w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6a46c1256abb11a880b696a27122044d
https://doi.org/10.1101/2021.04.30.21256380
https://doi.org/10.1101/2021.04.30.21256380
Autor:
Detlef Zillikens, Wiebke Pruessmann, Nina van Beek, Jasper Pruessmann, Enno Schmidt, Christoph M. Hammers, Christian D. Sadik, Maike M. Holtsche, Beke Linnemann
Publikováno v:
Acta Dermato-Venereologica, Vol 101, Iss 3, p adv00419 (2021)
Massive recruitment of eosinophils into the dermis is a hallmark of bullous pemphigoid pathogenesis. Identifying the chemoattractant(s) guiding eosinophils into the skin in bullous pemphigoid is a prerequisite to thera-peutic targeting of eosinophil
Autor:
Christoph M. Hammers, Jens Wrammert
Publikováno v:
Antibody Reports. 5:e756
The recombinant human antibody clone P5G6 (AX353) in an engineered scFv-Fc format detects by immunofluorescence cell-surface proteins on cryosections of monkey esophagus. The same antibody detects by ELISA recombinant human desmoglein 3 and desmoglei
Autor:
Mayumi Kamaguchi, Katharina Boch, Stefan W. Schneider, Ralf Ludwig, Christoph M. Hammers, Eva Hadaschik, Enno Schmidt, Detlef Zillikens, Stephanie Goletz
Publikováno v:
Journal of the American Academy of Dermatology. 85(6)
Background Pemphigoid diseases are a heterogeneous group of autoimmune blistering disorders characterized by predominant deposition of immunoglobulin G or immunoglobulin A autoantibodies against structural proteins of the dermoepidermal junction (DEJ
Autor:
Sadegh Mousavi, Sripriya Murthy, Enno Schmidt, Tanya Sezin, Maike M. Holtsche, Fibi Meshrkey, Claudia Attah, Christian D. Sadik, Malte Seutter, Detlef Zillikens, Christoph M. Hammers, Miles A. Nunn
Publikováno v:
JCI insight. 4(15)
The treatment of most autoimmune diseases still relies on systemic immunosuppression and is associated with severe side effects. The development of drugs that more specifically abrogate pathogenic pathways is therefore most desirable. In nature, such
Autor:
Kathrin Kalies, David Banczyk, Detlef Zillikens, Jürgen Westermann, Christoph M. Hammers, Girish Srinivas, Christoph T. Ellebrecht, Katja Bieber, John F. Baines, Ralf Ludwig, Sven Künzel
Publikováno v:
Journal of Autoimmunity. 68:14-22
Epidermolysis bullosa acquisita (EBA) is a chronic autoimmune blistering skin disease characterized by autoantibodies against type VII collagen (COL7). Immunization of SJL/J mice with recombinant murine COL7 results in break of tolerance and skin bli