Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Peter Vanderslice"'
Autor:
David Maxwell, Ananth Annapragada, Amy R. Caivano, Chandreshkumar Patel, Eric A. Tanifum, Market Robert, Peter Vanderslice, Ketan B. Ghaghada, Sayadeth Khounlo, Shahrzad Abbasi, Igor Stupin, Darren G. Woodside, Saakshi Bhayana, Richard A. F. Dixon, Deenadayalan Bakthavatsalam, John W. Craft, Zbigniew Starosolski, Biediger Ronald J, James T. Willerson
Publikováno v:
Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-15 (2018)
Scientific Reports, Vol 8, Iss 1, Pp 1-15 (2018)
Inflammation drives the degradation of atherosclerotic plaque, yet there are no non-invasive techniques available for imaging overall inflammation in atherosclerotic plaques, especially in the coronary arteries. To address this, we have developed a c
Autor:
David Maxwell, Sayadeth Khounlo, Darren G. Woodside, William G. Bornmann, Ronald J. Biediger, Wells S. Brown, Navin D. Warier, Amy R. Caivano, Bradley W. McIntyre, Richard A. F. Dixon, James T. Willerson, C. William Gundlach, Peter Vanderslice
Publikováno v:
Journal of Biological Chemistry. 288:19414-19428
Activation of the integrin family of cell adhesion receptors on progenitor cells may be a viable approach to enhance the effects of stem cell-based therapies by improving cell retention and engraftment. Here, we describe the synthesis and characteriz
Autor:
Ronald G. Tilton, Christy L. Munsch, Richard A. F. Dixon, Wanda S. LeJeune, Peter Vanderslice, Amy R. Caivano, Darren G. Woodside, Yuko J. Miyamoto, Bradley W. McIntyre, Sidney J. Sherwood, E. Radford Decker
Publikováno v:
Biochemical and biophysical research communications. 400(4)
The development of antagonists to the α4 integrin family of cell adhesion molecules has been an active area of pharmaceutical research to treat inflammatory and autoimmune diseases. Presently being tested in human clinical trials are compounds selec
Autor:
George W. Holland, Kurt L. Berens, Richard A. F. Dixon, Biediger Ronald J, Peter Vanderslice, Darren G. Woodside
Publikováno v:
Pulmonary pharmacologytherapeutics. 17(1)
Airway inflammation is a hallmark of respiratory diseases such as asthma and chronic obstructive pulmonary disease. Cell adhesion molecules play critical roles in the recruitment and migration of cells to sites of inflammation. Not surprisingly, thes
Autor:
Carol Merges, Ronald L. Nagel, D. Scott McLeod, T. Otsuji, Makoto Taomoto, Sahng Y. Kim, Mary E. Fabry, Sandra M. Suzuka, Peter Vanderslice, Gerard A. Lutty
Publikováno v:
Current eye research. 25(3)
Although sickle (SS) red cell-mediated vaso-occlusion in retina and resultant retinopathy is well documented, the effects of SS red cells on choroidal vasculature are poorly understood. The intent of this study was to determine, using a rat model, th
Autor:
Andrew J. Souers, Jonathan A. Ellman, Wendy Ankener, Timothy P. Kogan, Stephan S Schürer, Peter Vanderslice, Alex A. Virgilio, Henry E West
Publikováno v:
Bioorganicmedicinal chemistry letters. 8(17)
A library of 2302 small molecule beta-turn mimetics was screened for inhibition of the alpha 4 beta 1 integrin-CS1 splice variant binding interaction. Preliminary data revealed several active ligands, and validation with purified material culminated