Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Syvänen, Ac"'
Autor:
Manning A; Program in Medical and Population Genetics, Broad Institute, Cambridge, MA.; Center for Human Genetic Research, Department of Medicine, Massachusetts General Hospital, Boston, MA.; Department of Medicine, Harvard Medical School, Boston, MA., Highland HM; Human Genetics Center, The University of Texas MD Anderson Cancer Center and The University of Texas Health Science Center at Houston Graduate School of Biomedical Sciences, Houston, TX.; Department of Epidemiology, The University of North Carolina at Chapel Hill, Chapel Hill, NC., Gasser J; Program in Medical and Population Genetics, Broad Institute, Cambridge, MA., Sim X; Department of Biostatistics and Center for Statistical Genetics, School of Public Health, University of Michigan, Ann Arbor, MI.; Saw Swee Hock School of Public Health, National University of Singapore, Singapore., Tukiainen T; Program in Medical and Population Genetics, Broad Institute, Cambridge, MA.; Analytic and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital, Boston, MA.; Department of Genetics, Harvard Medical School, Boston, MA., Fontanillas P; Program in Medical and Population Genetics, Broad Institute, Cambridge, MA.; 23andMe, Mountain View, CA., Grarup N; The Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Rivas MA; Wellcome Trust Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, U.K., Mahajan A; Wellcome Trust Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, U.K., Locke AE; Department of Biostatistics and Center for Statistical Genetics, School of Public Health, University of Michigan, Ann Arbor, MI., Cingolani P; School of Computer Science, McGill University, Montreal, Canada.; McGill University and Génome Québec Innovation Centre, Montreal, Canada., Pers TH; Program in Medical and Population Genetics, Broad Institute, Cambridge, MA.; The Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; Divisions of Endocrinology and Genetics and Genomics and Center for Basic and Translational Obesity Research, Boston Children's Hospital, Boston, MA.; Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark., Viñuela A; Department of Twin Research & Genetic Epidemiology, King's College London, London, U.K.; Department of Genetic Medicine and Development, University of Geneva Medical School, Geneva, Switzerland.; Institute of Genetics and Genomics in Geneva, University of Geneva, Geneva, Switzerland., Brown AA; Wellcome Trust Sanger Institute, Hinxton, U.K.; Norwegian Centre for Mental Disorders Research and KG Jebsen Center for Psychosis Research, Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway., Wu Y; Department of Genetics, The University of North Carolina at Chapel Hill, Chapel Hill, NC., Flannick J; Program in Medical and Population Genetics, Broad Institute, Cambridge, MA.; Department of Molecular Biology, Massachusetts General Hospital, Boston, MA., Fuchsberger C; Department of Biostatistics and Center for Statistical Genetics, School of Public Health, University of Michigan, Ann Arbor, MI., Gamazon ER; Section of Genetic Medicine, Department of Medicine, The University of Chicago, Chicago, IL.; Academic Medical Center, University of Amsterdam, Amsterdam, the Netherlands., Gaulton KJ; Wellcome Trust Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, U.K.; Department of Pediatrics, University of California, San Diego, La Jolla, CA., Im HK; Section of Genetic Medicine, Department of Medicine, The University of Chicago, Chicago, IL., Teslovich TM; Department of Biostatistics and Center for Statistical Genetics, School of Public Health, University of Michigan, Ann Arbor, MI., Blackwell TW; Department of Biostatistics and Center for Statistical Genetics, School of Public Health, University of Michigan, Ann Arbor, MI., Bork-Jensen J; The Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Burtt NP; Program in Medical and Population Genetics, Broad Institute, Cambridge, MA., Chen Y; Wellcome Trust Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, U.K., Green T; Program in Medical and Population Genetics, Broad Institute, Cambridge, MA., Hartl C; Program in Medical and Population Genetics, Broad Institute, Cambridge, MA., Kang HM; Department of Biostatistics and Center for Statistical Genetics, School of Public Health, University of Michigan, Ann Arbor, MI., Kumar A; Wellcome Trust Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, U.K.; Chronic Disease Epidemiology Unit, Swiss Tropical and Public Health Institute, University of Basel, Basel, Switzerland., Ladenvall C; Diabetes and Endocrinology Unit, Department of Clinical Sciences Malmö, Lund University Diabetes Centre, Malmö, Sweden., Ma C; Department of Biostatistics and Center for Statistical Genetics, School of Public Health, University of Michigan, Ann Arbor, MI., Moutsianas L; Wellcome Trust Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, U.K., Pearson RD; Wellcome Trust Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, U.K., Perry JRB; Wellcome Trust Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, U.K.; Genetics of Complex Traits, University of Exeter Medical School, Exeter, U.K.; MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge, Cambridge, U.K., Rayner NW; Wellcome Trust Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, U.K.; Oxford Centre for Diabetes, Endocrinology & Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, U.K.; Department of Human Genetics, Wellcome Trust Sanger Institute, Hinxton, U.K., Robertson NR; Wellcome Trust Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, U.K.; Oxford Centre for Diabetes, Endocrinology & Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, U.K., Scott LJ; Department of Biostatistics and Center for Statistical Genetics, School of Public Health, University of Michigan, Ann Arbor, MI., van de Bunt M; Wellcome Trust Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, U.K.; Oxford Centre for Diabetes, Endocrinology & Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, U.K., Eriksson JG; Department of General Practice and Primary Health Care, University of Helsinki, Helsinki, Finland.; Unit of General Practice, Helsinki University Central Hospital, Helsinki, Finland.; Folkhälsan Research Center, Helsinki, Finland.; Vaasa Central Hospital, Vaasa, Finland.; Department of Health, National Institute for Health and Welfare, Helsinki, Finland., Jula A; Department of Health, National Institute for Health and Welfare, Helsinki, Finland., Koskinen S; Department of Health, National Institute for Health and Welfare, Helsinki, Finland., Lehtimäki T; Department of Clinical Chemistry, Fimlab Laboratories, University of Tampere School of Medicine, Tampere, Finland., Palotie A; Program in Medical and Population Genetics, Broad Institute, Cambridge, MA.; Center for Human Genetic Research, Department of Medicine, Massachusetts General Hospital, Boston, MA.; Institute for Molecular Medicine Finland, University of Helsinki, Helsinki, Finland., Raitakari OT; Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Turku, Finland.; Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, Finland., Jacobs SBR; Program in Medical and Population Genetics, Broad Institute, Cambridge, MA., Wessel J; Department of Epidemiology, Fairbanks School of Public Health, Indianapolis, IN.; Department of Medicine, Indiana University School of Medicine, Indianapolis, IN., Chu AY; Division of Preventive Medicine, Brigham and Women's Hospital, Boston, MA., Scott RA; MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge, Cambridge, U.K., Goodarzi MO; Division of Endocrinology, Diabetes & Metabolism, Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA.; Department of Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, CA., Blancher C; High-Throughput Genomics, Oxford Genomics Centre, Wellcome Trust Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, U.K., Buck G; High-Throughput Genomics, Oxford Genomics Centre, Wellcome Trust Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, U.K., Buck D; High-Throughput Genomics, Oxford Genomics Centre, Wellcome Trust Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, U.K., Chines PS; National Human Genome Research Institute, National Institutes of Health, Bethesda, MD., Gabriel S; Program in Medical and Population Genetics, Broad Institute, Cambridge, MA., Gjesing AP; The Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Groves CJ; Oxford Centre for Diabetes, Endocrinology & Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, U.K., Hollensted M; The Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Huyghe JR; Department of Biostatistics and Center for Statistical Genetics, School of Public Health, University of Michigan, Ann Arbor, MI., Jackson AU; Department of Biostatistics and Center for Statistical Genetics, School of Public Health, University of Michigan, Ann Arbor, MI., Jun G; Department of Biostatistics and Center for Statistical Genetics, School of Public Health, University of Michigan, Ann Arbor, MI., Justesen JM; The Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Mangino M; Department of Twin Research & Genetic Epidemiology, King's College London, London, U.K., Murphy J; Program in Medical and Population Genetics, Broad Institute, Cambridge, MA., Neville M; Oxford Centre for Diabetes, Endocrinology & Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, U.K., Onofrio R; Program in Medical and Population Genetics, Broad Institute, Cambridge, MA., Small KS; Department of Twin Research & Genetic Epidemiology, King's College London, London, U.K., Stringham HM; Department of Biostatistics and Center for Statistical Genetics, School of Public Health, University of Michigan, Ann Arbor, MI., Trakalo J; High-Throughput Genomics, Oxford Genomics Centre, Wellcome Trust Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, U.K., Banks E; Program in Medical and Population Genetics, Broad Institute, Cambridge, MA., Carey J; Program in Medical and Population Genetics, Broad Institute, Cambridge, MA., Carneiro MO; Program in Medical and Population Genetics, Broad Institute, Cambridge, MA., DePristo M; Program in Medical and Population Genetics, Broad Institute, Cambridge, MA., Farjoun Y; Program in Medical and Population Genetics, Broad Institute, Cambridge, MA., Fennell T; Program in Medical and Population Genetics, Broad Institute, Cambridge, MA., Goldstein JI; Program in Medical and Population Genetics, Broad Institute, Cambridge, MA.; Analytic and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital, Boston, MA., Grant G; Program in Medical and Population Genetics, Broad Institute, Cambridge, MA., Hrabé de Angelis M; Institute of Experimental Genetics, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; German Center for Diabetes Research (DZD), Neuherberg, Germany.; Institute of Experimental Genetics, School of Life Science Weihenstephan, Technische Universität München, Freising, Germany., Maguire J; Program in Medical and Population Genetics, Broad Institute, Cambridge, MA., Neale BM; Program in Medical and Population Genetics, Broad Institute, Cambridge, MA.; Analytic and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital, Boston, MA., Poplin R; Program in Medical and Population Genetics, Broad Institute, Cambridge, MA., Purcell S; Program in Medical and Population Genetics, Broad Institute, Cambridge, MA.; Center for Human Genetic Research, Department of Medicine, Massachusetts General Hospital, Boston, MA.; Department of Psychiatry, Icahn Institute for Genomics & Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, NY., Schwarzmayr T; Institute of Human Genetics, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany., Shakir K; Program in Medical and Population Genetics, Broad Institute, Cambridge, MA., Smith JD; Department of Genome Sciences, University of Washington School of Medicine, Seattle, WA., Strom TM; Institute of Human Genetics, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; Institute of Human Genetics, Technische Universität München, Neuherberg, Germany., Wieland T; Institute of Human Genetics, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany., Lindstrom J; Diabetes Prevention Unit, National Institute for Health and Welfare, Helsinki, Finland., Brandslund I; Department of Regional Health Research, University of Southern Denmark, Odense, Denmark.; Department of Clinical Biochemistry, Vejle Hospital, Vejle, Denmark., Christensen C; Department of Internal Medicine and Endocrinology, Vejle Hospital, Vejle, Denmark., Surdulescu GL; Department of Twin Research & Genetic Epidemiology, King's College London, London, U.K., Lakka TA; Department of Physiology, Institute of Biomedicine, University of Eastern Finland, Kuopio, Finland.; Kuopio Research Institute of Exercise Medicine, Kuopio, Finland.; Department of Clinical Physiology and Nuclear Medicine, Kuopio University Hospital, Kuopio, Finland., Doney ASF; Division of Cardiovascular & Diabetes Medicine, Medical Research Institute, Ninewells Hospital and Medical School, Dundee, U.K., Nilsson P; Department of Clinical Sciences, Faculty of Medicine, Lund University, Malmö, Sweden., Wareham NJ; MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge, Cambridge, U.K., Langenberg C; MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge, Cambridge, U.K., Varga TV; Department of Clinical Sciences, Lund University Diabetes Centre, and Genetic and Molecular Epidemiology Unit, Lund University, Malmö, Sweden., Franks PW; Department of Clinical Sciences, Lund University Diabetes Centre, and Genetic and Molecular Epidemiology Unit, Lund University, Malmö, Sweden.; Department of Nutrition, Harvard School of Public Health, Boston, MA.; Department of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden., Rolandsson O; Department of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden., Rosengren AH; Diabetes and Endocrinology Unit, Department of Clinical Sciences Malmö, Lund University Diabetes Centre, Malmö, Sweden., Farook VS; Department of Genetics, Texas Biomedical Research Institute, San Antonio, TX., Thameem F; Department of Medicine, The University of Texas Health Science Center, San Antonio, TX., Puppala S; Department of Genetics, Texas Biomedical Research Institute, San Antonio, TX., Kumar S; Department of Genetics, Texas Biomedical Research Institute, San Antonio, TX., Lehman DM; Department of Medicine, The University of Texas Health Science Center, San Antonio, TX., Jenkinson CP; Department of Medicine, The University of Texas Health Science Center, San Antonio, TX.; Research and Development Service, South Texas Veterans Health Care System, San Antonio, TX., Curran JE; Department of Genetics, Texas Biomedical Research Institute, San Antonio, TX., Hale DE; Department of Pediatrics, The University of Texas Health Science Center, San Antonio, TX., Fowler SP; Department of Medicine, The University of Texas Health Science Center, San Antonio, TX., Arya R; Department of Pediatrics, The University of Texas Health Science Center, San Antonio, TX., DeFronzo RA; Department of Medicine, The University of Texas Health Science Center, San Antonio, TX., Abboud HE; Department of Medicine, The University of Texas Health Science Center, San Antonio, TX., Syvänen AC; Molecular Medicine and Science for Life Laboratory, Department of Medical Sciences, Uppsala University, Uppsala, Sweden., Hicks PJ; Center for Genomics and Personalized Medicine Research, Wake Forest School of Medicine, Winston-Salem, NC.; Center for Diabetes Research, Wake Forest School of Medicine, Winston-Salem, NC.; Department of Biochemistry, Wake Forest School of Medicine, Winston-Salem, NC., Palmer ND; Center for Genomics and Personalized Medicine Research, Wake Forest School of Medicine, Winston-Salem, NC.; Center for Diabetes Research, Wake Forest School of Medicine, Winston-Salem, NC.; Department of Biochemistry, Wake Forest School of Medicine, Winston-Salem, NC., Ng MCY; Center for Genomics and Personalized Medicine Research, Wake Forest School of Medicine, Winston-Salem, NC.; Center for Diabetes Research, Wake Forest School of Medicine, Winston-Salem, NC., Bowden DW; Center for Genomics and Personalized Medicine Research, Wake Forest School of Medicine, Winston-Salem, NC.; Center for Diabetes Research, Wake Forest School of Medicine, Winston-Salem, NC.; Department of Biochemistry, Wake Forest School of Medicine, Winston-Salem, NC., Freedman BI; Section on Nephrology, Department of Internal Medicine, Wake Forest School of Medicine, Winston-Salem, NC., Esko T; Program in Medical and Population Genetics, Broad Institute, Cambridge, MA.; Department of Genetics, Harvard Medical School, Boston, MA.; Division of Endocrinology, Boston Children's Hospital, Boston, MA.; Estonian Genome Center, University of Tartu, Tartu, Estonia., Mägi R; Estonian Genome Center, University of Tartu, Tartu, Estonia., Milani L; Estonian Genome Center, University of Tartu, Tartu, Estonia., Mihailov E; Estonian Genome Center, University of Tartu, Tartu, Estonia., Metspalu A; Estonian Genome Center, University of Tartu, Tartu, Estonia., Narisu N; National Human Genome Research Institute, National Institutes of Health, Bethesda, MD., Kinnunen L; Department of Health, National Institute for Health and Welfare, Helsinki, Finland., Bonnycastle LL; National Human Genome Research Institute, National Institutes of Health, Bethesda, MD., Swift A; National Human Genome Research Institute, National Institutes of Health, Bethesda, MD., Pasko D; Genetics of Complex Traits, University of Exeter Medical School, Exeter, U.K., Wood AR; Genetics of Complex Traits, University of Exeter Medical School, Exeter, U.K., Fadista J; Diabetes and Endocrinology Unit, Department of Clinical Sciences Malmö, Lund University Diabetes Centre, Malmö, Sweden., Pollin TI; Program in Personalized and Genomic Medicine, Department of Medicine, University of Maryland, Baltimore, MD., Barzilai N; Departments of Medicine and Genetics, Albert Einstein College of Medicine, New York, NY., Atzmon G; Departments of Medicine and Genetics, Albert Einstein College of Medicine, New York, NY.; Faculty of Natural Sciences, University of Haifa, Haifa, Israel., Glaser B; Endocrinology and Metabolism Service, Hadassah-Hebrew University Medical Center, Jerusalem, Israel., Thorand B; German Center for Diabetes Research (DZD), Neuherberg, Germany.; Institute of Epidemiology II, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany., Strauch K; Institute of Genetic Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; Department of Genetic Epidemiology, Institute of Medical Informatics, Biometry and Epidemiology, Ludwig-Maximilians-Universität, Munich, Germany., Peters A; German Center for Diabetes Research (DZD), Neuherberg, Germany.; Institute of Epidemiology II, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; Deutsches Zentrum für Herz-Kreislauf-Forschung (DZHK), Partner Site Munich Heart Alliance, Munich, Germany., Roden M; Institute of Clinical Diabetology, German Diabetes Center, Leibniz Center for Diabetes Research at Heinrich Heine University, Düsseldorf, Germany.; German Center for Diabetes Research, Partner Düsseldorf, Germany., Müller-Nurasyid M; Institute of Genetic Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; Department of Genetic Epidemiology, Institute of Medical Informatics, Biometry and Epidemiology, Ludwig-Maximilians-Universität, Munich, Germany.; Deutsches Zentrum für Herz-Kreislauf-Forschung (DZHK), Partner Site Munich Heart Alliance, Munich, Germany.; Department of Medicine I, University Hospital Grosshadern, Ludwig-Maximilians-Universität, Munich, Germany., Liang L; Department of Epidemiology, Harvard School of Public Health, Boston, MA.; Department of Biostatistics, Harvard School of Public Health, Boston, MA., Kriebel J; German Center for Diabetes Research (DZD), Neuherberg, Germany.; Institute of Epidemiology II, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; Research Unit Molecular Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany., Illig T; Research Unit Molecular Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; Hannover Unified Biobank, Hannover Medical School, Hannover, Germany.; Institute of Human Genetics, Hannover Medical School, Hannover, Germany., Grallert H; German Center for Diabetes Research (DZD), Neuherberg, Germany.; Institute of Epidemiology II, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; Research Unit Molecular Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany., Gieger C; Institute of Genetic Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany., Meisinger C; Institute of Epidemiology II, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany., Lannfelt L; Geriatrics, Department of Public Health and Caring Sciences, Uppsala University, Uppsala, Sweden., Musani SK; Jackson Heart Study, University of Mississippi Medical Center, Jackson, MS., Griswold M; Center of Biostatistics and Bioinformatics, University of Mississippi Medical Center, Jackson, MS., Taylor HA Jr; Department of Medicine, University of Mississippi Medical Center, Jackson, MS., Wilson G Sr; College of Public Services, Jackson State University, Jackson, MS., Correa A; Department of Medicine, University of Mississippi Medical Center, Jackson, MS., Oksa H; Pirkanmaa Hospital District, Tampere, Finland., Scott WR; Department of Epidemiology and Biostatistics, Imperial College London, London, U.K., Afzal U; Department of Epidemiology and Biostatistics, Imperial College London, London, U.K., Tan ST; Cardiovascular Sciences, National Heart and Lung Institute, Imperial College London, London, U.K.; Department of Cardiology, Ealing Hospital NHS Trust, Southall, U.K., Loh M; Department of Epidemiology and Biostatistics, Imperial College London, London, U.K.; Institute of Health Sciences, University of Oulu, Oulu, Finland.; Translational Laboratory in Genetic Medicine, Agency for Science, Technology and Research (A*STAR), Singapore., Chambers JC; Department of Epidemiology and Biostatistics, Imperial College London, London, U.K.; Department of Cardiology, Ealing Hospital NHS Trust, Southall, U.K.; Imperial College Healthcare NHS Trust, Imperial College London, London, U.K., Sehmi J; Cardiovascular Sciences, National Heart and Lung Institute, Imperial College London, London, U.K.; Department of Cardiology, Ealing Hospital NHS Trust, Southall, U.K., Kooner JS; Cardiovascular Sciences, National Heart and Lung Institute, Imperial College London, London, U.K., Lehne B; Department of Epidemiology and Biostatistics, Imperial College London, London, U.K., Cho YS; Department of Biomedical Science, Hallym University, Chuncheon, Republic of Korea., Lee JY; Ministry of Health and Welfare, Seoul, Republic of Korea., Han BG; Center for Genome Science, Korea National Research Institute of Health, Chungcheongbuk-do, Republic of Korea., Käräjämäki A; Vaasa Health Care Center, Vaasa, Finland.; Department of Primary Health Care, Vaasa Central Hospital, Vaasa, Finland., Qi Q; Department of Nutrition, Harvard School of Public Health, Boston, MA.; Department of Epidemiology and Population Health, Albert Einstein College of Medicine, New York, NY., Qi L; Department of Nutrition, Harvard School of Public Health, Boston, MA.; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA., Huang J; Department of Epidemiology, Harvard School of Public Health, Boston, MA., Hu FB; Department of Nutrition, Harvard School of Public Health, Boston, MA.; Department of Epidemiology, Harvard School of Public Health, Boston, MA., Melander O; Hypertension and Cardiovascular Disease, Department of Clinical Sciences, Lund University, Malmö, Sweden., Orho-Melander M; Diabetes and Cardiovascular Disease-Genetic Epidemiology, Department of Clinical Sciences, Lund University, Malmö, Sweden., Below JE; Human Genetics Center, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX., Aguilar D; Cardiovascular Division, Baylor College of Medicine, Houston, TX., Wong TY; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore.; Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore., Liu J; Saw Swee Hock School of Public Health, National University of Singapore, Singapore.; Division of Human Genetics, Genome Institute of Singapore, Agency for Science, Technology and Research (A*STAR), Singapore., Khor CC; Saw Swee Hock School of Public Health, National University of Singapore, Singapore.; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore.; Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.; Division of Human Genetics, Genome Institute of Singapore, Agency for Science, Technology and Research (A*STAR), Singapore.; Department of Paediatrics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore., Chia KS; Saw Swee Hock School of Public Health, National University of Singapore, Singapore., Lim WY; Saw Swee Hock School of Public Health, National University of Singapore, Singapore., Cheng CY; Saw Swee Hock School of Public Health, National University of Singapore, Singapore.; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore.; Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.; Office of Clinical Sciences, Centre for Quantitative Medicine, Duke-NUS Graduate Medical School Singapore, Singapore., Chan E; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore., Tai ES; Saw Swee Hock School of Public Health, National University of Singapore, Singapore.; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.; Cardiovascular & Metabolic Disorders Program, Duke-NUS Graduate Medical School Singapore, Singapore., Aung T; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore.; Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore., Linneberg A; Research Centre for Prevention and Health, Glostrup University Hospital, Glostrup, Denmark.; Department of Clinical Experimental Research, Rigshospitalet, Glostrup, Denmark.; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Isomaa B; Folkhälsan Research Center, Helsinki, Finland.; Department of Social Services and Health Care, Jakobstad, Finland., Meitinger T; Institute of Human Genetics, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; Institute of Human Genetics, Technische Universität München, Neuherberg, Germany.; Deutsches Zentrum für Herz-Kreislauf-Forschung (DZHK), Partner Site Munich Heart Alliance, Munich, Germany., Tuomi T; Folkhälsan Research Center, Helsinki, Finland.; Department of Endocrinology, Helsinki University Central Hospital, Helsinki, Finland., Hakaste L; Folkhälsan Research Center, Helsinki, Finland., Kravic J; Diabetes and Endocrinology Unit, Department of Clinical Sciences Malmö, Lund University Diabetes Centre, Malmö, Sweden., Jørgensen ME; Steno Diabetes Center, Gentofte, Denmark., Lauritzen T; Section of General Practice, Department of Public Health, Aarhus University, Aarhus, Denmark., Deloukas P; Department of Human Genetics, Wellcome Trust Sanger Institute, Hinxton, U.K., Stirrups KE; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, U.K.; Department of Haematology, University of Cambridge, Cambridge, U.K., Owen KR; Oxford Centre for Diabetes, Endocrinology & Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, U.K.; Oxford NIHR Biomedical Research Centre, Oxford University Hospitals Trust, Oxford, U.K., Farmer AJ; Department of Primary Care Health Sciences, University of Oxford, Oxford, U.K., Frayling TM; Genetics of Complex Traits, University of Exeter Medical School, Exeter, U.K., O'Rahilly SP; Metabolic Research Laboratories, Institute of Metabolic Science, University of Cambridge, Cambridge, U.K., Walker M; Institute of Cellular Medicine, University of Newcastle, Newcastle, U.K., Levy JC; Oxford Centre for Diabetes, Endocrinology & Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, U.K., Hodgkiss D; Department of Twin Research & Genetic Epidemiology, King's College London, London, U.K., Hattersley AT; University of Exeter Medical School, Exeter, U.K., Kuulasmaa T; Internal Medicine, Institute of Clinical Medicine, Faculty of Health Sciences, University of Eastern Finland, Kuopio, Finland., Stančáková A; Internal Medicine, Institute of Clinical Medicine, Faculty of Health Sciences, University of Eastern Finland, Kuopio, Finland., Barroso I; Department of Human Genetics, Wellcome Trust Sanger Institute, Hinxton, U.K.; Metabolic Research Laboratories, Institute of Metabolic Science, University of Cambridge, Cambridge, U.K., Bharadwaj D; Functional Genomics Unit, CSIR-Institute of Genomics & Integrative Biology, New Delhi, India., Chan J; Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong, China.; Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Hong Kong, China.; Hong Kong Institute of Diabetes and Obesity, The Chinese University of Hong Kong, Hong Kong, China., Chandak GR; CSIR-Centre for Cellular & Molecular Biology, Hyderabad, India., Daly MJ; Analytic and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital, Boston, MA., Donnelly PJ; Wellcome Trust Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, U.K.; Department of Statistics, University of Oxford, Oxford, U.K., Ebrahim SB; Centre for Chronic Disease Control, New Delhi, India., Elliott P; Department of Epidemiology and Biostatistics, Imperial College London, London, U.K.; MRC-PHE Centre for Environment & Health, Imperial College London, London, U.K., Fingerlin T; Department of Epidemiology, Colorado School of Public Health, University of Colorado, Aurora, CO., Froguel P; Genomics and Molecular Physiology, CNRS Institut de Biologie de Lille, Lille, France., Hu C; Department of Endocrinology and Metabolism, Shanghai Diabetes Institute, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai, China., Jia W; Department of Endocrinology and Metabolism, Shanghai Diabetes Institute, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai, China., Ma RCW; Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong, China.; Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Hong Kong, China.; Hong Kong Institute of Diabetes and Obesity, The Chinese University of Hong Kong, Hong Kong, China., McVean G; Wellcome Trust Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, U.K., Park T; Interdisciplinary Program in Bioinformatics, Seoul National University, Seoul, Republic of Korea.; Department of Statistics, Seoul National University, Seoul, Republic of Korea., Prabhakaran D; Centre for Chronic Disease Control, New Delhi, India., Sandhu M; Department of Human Genetics, Wellcome Trust Sanger Institute, Hinxton, U.K.; Institute of Public Health, Department of Public Health and Primary Care, University of Cambridge, Cambridge, U.K., Scott J; Cardiovascular Sciences, National Heart and Lung Institute, Imperial College London, London, U.K., Sladek R; McGill University and Génome Québec Innovation Centre, Montreal, Canada.; Department of Human Genetics, McGill University, Montreal, Canada.; Division of Endocrinology and Metabolism, Department of Medicine, McGill University, Montreal, Canada., Tandon N; Department of Endocrinology and Metabolism, All India Institute of Medical Sciences, New Delhi, India., Teo YY; Saw Swee Hock School of Public Health, National University of Singapore, Singapore.; Life Sciences Institute, National University of Singapore, Singapore.; Department of Statistics and Applied Probability, National University of Singapore, Singapore., Zeggini E; Department of Human Genetics, Wellcome Trust Sanger Institute, Hinxton, U.K., Watanabe RM; Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA.; Department of Physiology and Biophysics, Keck School of Medicine, University of Southern California, Los Angeles, CA.; Diabetes & Obesity Research Institute, Keck School of Medicine, University of Southern California, Los Angeles, CA., Koistinen HA; Department of Health, National Institute for Health and Welfare, Helsinki, Finland.; Department of Medicine and Abdominal Center, Endocrinology, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland.; Minerva Foundation Institute for Medical Research, Helsinki, Finland., Kesaniemi YA; Institute of Clinical Medicine, Faculty of Medicine, University of Oulu, Oulu, Finland., Uusitupa M; Institute of Public Health and Clinical Nutrition, University of Eastern Finland, Kuopio, Finland., Spector TD; Department of Twin Research & Genetic Epidemiology, King's College London, London, U.K., Salomaa V; Department of Health, National Institute for Health and Welfare, Helsinki, Finland., Rauramaa R; Foundation for Research in Health Exercise and Nutrition, Kuopio Research Institute of Exercise Medicine, Kuopio, Finland., Palmer CNA; Pat Macpherson Centre for Pharmacogenetics and Pharmacogenomics, Medical Research Institute, Ninewells Hospital and Medical School, Dundee, U.K., Prokopenko I; Wellcome Trust Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, U.K.; Oxford Centre for Diabetes, Endocrinology & Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, U.K.; Department of Genomics of Common Disease, School of Public Health, Imperial College London, London, U.K., Morris AD; Division for Molecular Medicine, Clinical Research Centre, Ninewells Hospital and Medical School, Dundee, U.K., Bergman RN; Diabetes and Obesity Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA., Collins FS; National Human Genome Research Institute, National Institutes of Health, Bethesda, MD., Lind L; Department of Medical Sciences, Uppsala University, Uppsala, Sweden., Ingelsson E; Molecular Medicine and Science for Life Laboratory, Department of Medical Sciences, Uppsala University, Uppsala, Sweden.; Division of Cardiovascular Medicine, Department of Medicine, Stanford University School of Medicine, Stanford, CA., Tuomilehto J; Diabetes Prevention Unit, National Institute for Health and Welfare, Helsinki, Finland.; Center for Vascular Prevention, Danube University Krems, Krems, Austria.; Diabetes Research Group, King Abdulaziz University, Jeddah, Saudi Arabia.; Dasman Diabetes Institute, Dasman, Kuwait., Karpe F; Oxford Centre for Diabetes, Endocrinology & Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, U.K.; Oxford NIHR Biomedical Research Centre, Oxford University Hospitals Trust, Oxford, U.K., Groop L; Diabetes and Endocrinology Unit, Department of Clinical Sciences Malmö, Lund University Diabetes Centre, Malmö, Sweden., Jørgensen T; Research Centre for Prevention and Health, Glostrup University Hospital, Glostrup, Denmark.; Faculty of Medicine, University of Aalborg, Aalborg, Denmark., Hansen T; The Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; Faculty of Health Sciences, University of Southern Denmark, Odense, Denmark., Pedersen O; The Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Kuusisto J; Internal Medicine, Institute of Clinical Medicine, Faculty of Health Sciences, University of Eastern Finland, Kuopio, Finland.; Kuopio University Hospital, Kuopio, Finland., Abecasis G; Department of Biostatistics and Center for Statistical Genetics, School of Public Health, University of Michigan, Ann Arbor, MI., Bell GI; Departments of Medicine and Human Genetics, The University of Chicago, Chicago, IL., Blangero J; Department of Genetics, Texas Biomedical Research Institute, San Antonio, TX., Cox NJ; Section of Genetic Medicine, Department of Medicine, The University of Chicago, Chicago, IL., Duggirala R; Department of Genetics, Texas Biomedical Research Institute, San Antonio, TX., Seielstad M; Department of Laboratory Medicine, Institute for Human Genetics, University of California, San Francisco, San Francisco, CA.; Blood Systems Research Institute, San Francisco, CA., Wilson JG; Department of Physiology and Biophysics, University of Mississippi Medical Center, Jackson, MS., Dupuis J; Department of Biostatistics, Boston University School of Public Health, Boston, MA.; Framingham Heart Study, National Heart, Lung, and Blood Institute, Framingham, MA., Ripatti S; Wellcome Trust Sanger Institute, Hinxton, U.K.; Institute for Molecular Medicine Finland, University of Helsinki, Helsinki, Finland.; Hjelt Institute, University of Helsinki, Helsinki, Finland., Hanis CL; Human Genetics Center, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX., Florez JC; Program in Medical and Population Genetics, Broad Institute, Cambridge, MA.; Center for Human Genetic Research, Department of Medicine, Massachusetts General Hospital, Boston, MA.; Department of Medicine, Harvard Medical School, Boston, MA.; Diabetes Research Center (Diabetes Unit), Department of Medicine, Massachusetts General Hospital, Boston, MA., Mohlke KL; Department of Genetics, The University of North Carolina at Chapel Hill, Chapel Hill, NC., Meigs JB; Program in Medical and Population Genetics, Broad Institute, Cambridge, MA.; Department of Medicine, Harvard Medical School, Boston, MA.; Division of General Internal Medicine, Massachusetts General Hospital, Boston, MA., Laakso M; Internal Medicine, Institute of Clinical Medicine, Faculty of Health Sciences, University of Eastern Finland, Kuopio, Finland.; Kuopio University Hospital, Kuopio, Finland., Morris AP; Wellcome Trust Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, U.K.; Estonian Genome Center, University of Tartu, Tartu, Estonia.; Department of Biostatistics, University of Liverpool, Liverpool, U.K., Boehnke M; Department of Biostatistics and Center for Statistical Genetics, School of Public Health, University of Michigan, Ann Arbor, MI., Altshuler D; Program in Medical and Population Genetics, Broad Institute, Cambridge, MA.; Department of Medicine, Harvard Medical School, Boston, MA.; Department of Genetics, Harvard Medical School, Boston, MA.; Department of Molecular Biology, Massachusetts General Hospital, Boston, MA.; Diabetes Research Center (Diabetes Unit), Department of Medicine, Massachusetts General Hospital, Boston, MA.; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA., McCarthy MI; Wellcome Trust Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, U.K.; Oxford Centre for Diabetes, Endocrinology & Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, U.K.; Oxford NIHR Biomedical Research Centre, Oxford University Hospitals Trust, Oxford, U.K., Gloyn AL; Wellcome Trust Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, U.K.; Oxford Centre for Diabetes, Endocrinology & Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, U.K.; Oxford NIHR Biomedical Research Centre, Oxford University Hospitals Trust, Oxford, U.K., Lindgren CM; Program in Medical and Population Genetics, Broad Institute, Cambridge, MA.; Wellcome Trust Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, U.K.; Big Data Institute, Li Ka Shing Centre for Health Information and Discovery, University of Oxford, Oxford, U.K.
Publikováno v:
Diabetes [Diabetes] 2017 Jul; Vol. 66 (7), pp. 2019-2032. Date of Electronic Publication: 2017 Mar 24.
Autor:
Shungin D; Department of Public Health and Clinical Medicine, Unit of Medicine, Umeå University, Umeå 901 87, Sweden.; Department of Clinical Sciences, Genetic & Molecular Epidemiology Unit, Lund University Diabetes Center, Skåne University Hosptial, Malmö 205 02, Sweden.; Department of Odontology, Umeå University, Umeå 901 85, Sweden., Winkler TW; Department of Genetic Epidemiology, Institute of Epidemiology and Preventive Medicine, University of Regensburg, D-93053 Regensburg, Germany., Croteau-Chonka DC; Department of Genetics, University of North Carolina, Chapel Hill, NC 27599, USA.; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA., Ferreira T; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK., Locke AE; Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, MI 48109, USA., Mägi R; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.; Estonian Genome Center, University of Tartu, Tartu 51010, Estonia., Strawbridge RJ; Atherosclerosis Research Unit, Center for Molecular Medicine, Department of Medicine, Karolinska Institutet, Stockholm 17176, Sweden., Pers TH; Divisions of Endocrinology and Genetics and Center for Basic and Translational Obesity Research, Boston Children's Hospital, Boston, MA 02115, USA.; Broad Institute of the Massachusetts Institute of Technology and Harvard University, Cambridge 02142, MA, USA.; Department of Genetics, Harvard Medical School, Boston, MA 02115, USA.; Center for Biological Sequence Analysis, Department of Systems Biology, Technical University of Denmark, Lyngby 2800, Denmark., Fischer K; Estonian Genome Center, University of Tartu, Tartu 51010, Estonia., Justice AE; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA., Workalemahu T; Department of Nutrition, Harvard School of Public Health, Boston, MA, USA., Wu JMW; Department of Biostatistics, Boston University School of Public Health, Boston, MA 02118, USA., Buchkovich ML; Department of Genetics, University of North Carolina, Chapel Hill, NC 27599, USA., Heard-Costa NL; National Heart, Lung, and Blood Institute, the Framingham Heart Study, Framingham MA 01702, USA.; Department of Neurology, Boston University School of Medicine, Boston, MA 02118, USA., Roman TS; Department of Genetics, University of North Carolina, Chapel Hill, NC 27599, USA., Drong AW; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK., Song C; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm 17177, Sweden.; Science for Life Laboratory, Uppsala University, Uppsala 75185, Sweden.; Department of Medical Sciences, Molecular Epidemiology, Uppsala University, Uppsala 75185, Sweden., Gustafsson S; Science for Life Laboratory, Uppsala University, Uppsala 75185, Sweden.; Department of Medical Sciences, Molecular Epidemiology, Uppsala University, Uppsala 75185, Sweden., Day FR; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge Biomedical Campus, Cambridge, CB2 0QQ, UK., Esko T; Estonian Genome Center, University of Tartu, Tartu 51010, Estonia.; Divisions of Endocrinology and Genetics and Center for Basic and Translational Obesity Research, Boston Children's Hospital, Boston, MA 02115, USA.; Broad Institute of the Massachusetts Institute of Technology and Harvard University, Cambridge 02142, MA, USA.; Department of Genetics, Harvard Medical School, Boston, MA 02115, USA., Fall T; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm 17177, Sweden.; Science for Life Laboratory, Uppsala University, Uppsala 75185, Sweden.; Department of Medical Sciences, Molecular Epidemiology, Uppsala University, Uppsala 75185, Sweden., Kutalik Z; Institute of Social and Preventive Medicine (IUMSP), Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne 1010, Switzerland.; Swiss Institute of Bioinformatics, Lausanne 1015, Switzerland.; Department of Medical Genetics, University of Lausanne, Lausanne 1005, Switzerland., Luan J; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge Biomedical Campus, Cambridge, CB2 0QQ, UK., Randall JC; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.; Wellcome Trust Sanger Institute, Hinxton, Cambridge CB10 1SA, UK., Scherag A; Institute for Medical Informatics, Biometry and Epidemiology (IMIBE), University Hospital Essen, Essen, Germany.; Clinical Epidemiology, Integrated Research and Treatment Center, Center for Sepsis Control and Care (CSCC), Jena University Hospital, Jena, Germany., Vedantam S; Divisions of Endocrinology and Genetics and Center for Basic and Translational Obesity Research, Boston Children's Hospital, Boston, MA 02115, USA.; Broad Institute of the Massachusetts Institute of Technology and Harvard University, Cambridge 02142, MA, USA., Wood AR; Genetics of Complex Traits, University of Exeter Medical School, University of Exeter, Exeter EX1 2LU, UK., Chen J; Department of Internal Medicine, Division of Cardiovascular Medicine, University of Michigan, Ann Arbor, MI, USA., Fehrmann R; Department of Genetics, University Medical Center Groningen, University of Groningen, 9700 RB Groningen, The Netherlands., Karjalainen J; Department of Genetics, University Medical Center Groningen, University of Groningen, 9700 RB Groningen, The Netherlands., Kahali B; Department of Internal Medicine, Division of Gastroenterology, and Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI 48109., Liu CT; Department of Biostatistics, Boston University School of Public Health, Boston, MA 02118, USA., Schmidt EM; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, USA., Absher D; HudsonAlpha Institute for Biotechnology, Huntsville, AL 35806, USA., Amin N; Genetic Epidemiology Unit, Department of Epidemiology, Erasmus MC University Medical Center, 3015 GE Rotterdam, The Netherlands., Anderson D; Telethon Institute for Child Health Research, Centre for Child Health Research, The University of Western Australia, Perth, Western Australia 6008, Australia., Beekman M; Netherlands Consortium for Healthy Aging (NCHA), Leiden University Medical Center, Leiden 2300 RC, The Netherlands.; Department of Molecular Epidemiology, Leiden University Medical Center, 2300 RC Leiden, The Netherlands., Bragg-Gresham JL; Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, MI 48109, USA.; Kidney Epidemiology and Cost Center, University of Michigan, Ann Arbor, MI 48109., Buyske S; Department of Statistics & Biostatistics, Rutgers University, Piscataway, NJ USA.; Department of Genetics, Rutgers University, Piscataway, NJ USA., Demirkan A; Genetic Epidemiology Unit, Department of Epidemiology, Erasmus MC University Medical Center, 3015 GE Rotterdam, The Netherlands.; Department of Human Genetics, Leiden University Medical Center, 2333 ZC Leiden, The Netherlands., Ehret GB; Center for Complex Disease Genomics, McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.; Cardiology, Department of Specialties of Internal Medicine, Geneva University Hospital, Geneva 1211, Switzerland., Feitosa MF; Department of Genetics, Washington University School of Medicine, St. Louis, MO 63110, USA., Goel A; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.; Division of Cardiovacular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford OX3 9DU, UK., Jackson AU; Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, MI 48109, USA., Johnson T; Swiss Institute of Bioinformatics, Lausanne 1015, Switzerland.; Department of Medical Genetics, University of Lausanne, Lausanne 1005, Switzerland.; University Institute for Social and Preventative Medecine, Centre Hospitalier Universitaire Vaudois (CHUV), University of Lausanne, Lausanne 1005, Switzerland., Kleber ME; Vth Department of Medicine (Nephrology, Hypertensiology, Endocrinology, Diabetology, Rheumatology), Medical Faculty of Mannheim, University of Heidelberg, Germany.; Department of Internal Medicine II, Ulm University Medical Centre, D-89081 Ulm, Germany., Kristiansson K; National Institute for Health and Welfare, FI-00271 Helsinki, Finland., Mangino M; Department of Twin Research and Genetic Epidemiology, King's College London, London SE1 7EH, UK., Leach IM; Department of Cardiology, University Medical Center Groningen, University of Groningen, 9700RB Groningen, The Netherlands., Medina-Gomez C; Netherlands Consortium for Healthy Aging (NCHA), 3015GE Rotterdam, The Netherlands.; Department of Epidemiology, Erasmus MC University Medical Center, 3015GE Rotterdam, The Netherlands.; Department of Internal Medicine, Erasmus MC University Medical Center, 3015GE Rotterdam, The Netherlands., Palmer CD; Divisions of Endocrinology and Genetics and Center for Basic and Translational Obesity Research, Boston Children's Hospital, Boston, MA 02115, USA.; Broad Institute of the Massachusetts Institute of Technology and Harvard University, Cambridge 02142, MA, USA., Pasko D; Genetics of Complex Traits, University of Exeter Medical School, University of Exeter, Exeter EX1 2LU, UK., Pechlivanis S; Institute for Medical Informatics, Biometry and Epidemiology (IMIBE), University Hospital Essen, Essen, Germany., Peters MJ; Netherlands Consortium for Healthy Aging (NCHA), 3015GE Rotterdam, The Netherlands.; Department of Internal Medicine, Erasmus MC University Medical Center, 3015GE Rotterdam, The Netherlands., Prokopenko I; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford OX3 7LJ, UK.; Department of Genomics of Common Disease, School of Public Health, Imperial College London, Hammersmith Hospital, London, UK., Stančáková A; University of Eastern Finland, FI-70210 Kuopio, Finland., Sung YJ; Division of Biostatistics, Washington University School of Medicine, St. Louis, MO 63110, USA., Tanaka T; Translational Gerontology Branch, National Institute on Aging, Baltimore MD 21225, USA., Teumer A; Interfaculty Institute for Genetics and Functional Genomics, University Medicine Greifswald, D-17475 Greifswald, Germany., Van Vliet-Ostaptchouk JV; Department of Endocrinology, University of Groningen, University Medical Center Groningen, Groningen, 9700 RB, The Netherlands., Yengo L; CNRS UMR 8199, F-59019 Lille, France.; European Genomic Institute for Diabetes, F-59000 Lille, France.; Université de Lille 2, F-59000 Lille, France., Zhang W; Ealing Hospital NHS Trust, Middlesex UB1 3HW, UK.; Department of Epidemiology and Biostatistics, Imperial College London, London W2 1PG, UK., Albrecht E; Institute of Genetic Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, D-85764 Neuherberg, Germany., Ärnlöv J; Science for Life Laboratory, Uppsala University, Uppsala 75185, Sweden.; Department of Medical Sciences, Molecular Epidemiology, Uppsala University, Uppsala 75185, Sweden.; School of Health and Social Studies, Dalarna University, Falun, Sweden., Arscott GM; PathWest Laboratory Medicine of Western Australia, NEDLANDS, Western Australia 6009, Australia., Bandinelli S; Geriatric Unit, Azienda Sanitaria Firenze (ASF), Florence, Italy., Barrett A; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford OX3 7LJ, UK., Bellis C; Department of Genetics, Texas Biomedical Research Institute, San Antonio, TX, USA.; Genomics Research Centre, Institute of Health and Biomedical Innovation, Queensland University of Technology, Brisbane, Queensland, Australia., Bennett AJ; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford OX3 7LJ, UK., Berne C; Department of Medical Sciences, Endocrinology, Diabetes and Metabolism, Uppsala University, Uppsala 75185, Sweden., Blüher M; Integrated Research and Treatment Center (IFB) Adiposity Diseases, University of Leipzig, D-04103 Leipzig, Germany.; Department of Medicine, University of Leipzig, D-04103 Leipzig, Germany., Böhringer S; Netherlands Consortium for Healthy Aging (NCHA), Leiden University Medical Center, Leiden 2300 RC, The Netherlands.; Department of Medical Statistics and Bioinformatics, Leiden University Medical Center, 2300 RC Leiden, The Netherlands., Bonnet F; Inserm UMR991, Department of Endocrinology, University of Rennes, F-35000 Rennes, France., Böttcher Y; Integrated Research and Treatment Center (IFB) Adiposity Diseases, University of Leipzig, D-04103 Leipzig, Germany., Bruinenberg M; LifeLines Cohort Study, University Medical Center Groningen, University of Groningen, 9700 RB Groningen, The Netherlands., Carba DB; USC-Office of Population Studies Foundation, Inc., University of San Carlos, Cebu City 6000, Philippines., Caspersen IH; Department of Biology, Norwegian University of Science and Technology, Trondheim, Norway., Clarke R; Clinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford OX3 7LF, UK., Daw EW; Department of Genetics, Washington University School of Medicine, St. Louis, MO 63110, USA., Deelen J; Netherlands Consortium for Healthy Aging (NCHA), Leiden University Medical Center, Leiden 2300 RC, The Netherlands.; Department of Molecular Epidemiology, Leiden University Medical Center, 2300 RC Leiden, The Netherlands., Deelman E; Information Sciences Institute, University of Southern California, Marina del Rey, California, USA., Delgado G; Vth Department of Medicine (Nephrology, Hypertensiology, Endocrinology, Diabetology, Rheumatology), Medical Faculty of Mannheim, University of Heidelberg, Germany., Doney AS; Medical Research Institute, University of Dundee, Ninewells Hospital and Medical School, Dundee DD1 9SY, UK., Eklund N; National Institute for Health and Welfare, FI-00271 Helsinki, Finland.; Institute for Molecular Medicine, University of Helsinki, FI-00014 Helsinki, Finland., Erdos MR; Medical Genomics and Metabolic Genetics Branch, National Human Genome Research Institute, NIH, Bethesda, MD 20892, USA., Estrada K; Broad Institute of the Massachusetts Institute of Technology and Harvard University, Cambridge 02142, MA, USA.; Department of Internal Medicine, Erasmus MC University Medical Center, 3015GE Rotterdam, The Netherlands.; Analytic and Translational Genetics Unit, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA., Eury E; CNRS UMR 8199, F-59019 Lille, France.; European Genomic Institute for Diabetes, F-59000 Lille, France.; Université de Lille 2, F-59000 Lille, France., Friedrich N; Institute of Clinical Chemistry and Laboratory Medicine, University Medicine Greifswald, D-17475 Greifswald, Germany., Garcia ME; Laboratory of Epidemiology and Population Sciences, National Institute on Aging, NIH, Bethesda, MD 20892, USA., Giedraitis V; Department of Public Health and Caring Sciences, Geriatrics, Uppsala University, Uppsala 75185, Sweden., Gigante B; Division of Cardiovascular Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden, Stockholm 17177, Sweden., Go AS; Kaiser Permanente, Division of Research, Oakland, CA 94612, USA., Golay A; Service of Therapeutic Education for Diabetes, Obesity and Chronic Diseases, Geneva University Hospital, Geneva CH-1211, Switzerland., Grallert H; Institute of Genetic Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, D-85764 Neuherberg, Germany.; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, D-85764 Neuherberg, Germany.; German Center for Diabetes Research (DZD), Neuherberg, Germany., Grammer TB; Vth Department of Medicine (Nephrology, Hypertensiology, Endocrinology, Diabetology, Rheumatology), Medical Faculty of Mannheim, University of Heidelberg, Germany., Gräßler J; Department of Medicine III, University Hospital Carl Gustav Carus, Technische Universität Dresden, D-01307 Dresden, Germany., Grewal J; Ealing Hospital NHS Trust, Middlesex UB1 3HW, UK.; Department of Epidemiology and Biostatistics, Imperial College London, London W2 1PG, UK., Groves CJ; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford OX3 7LJ, UK., Haller T; Estonian Genome Center, University of Tartu, Tartu 51010, Estonia., Hallmans G; Department of Public Health and Clinical Medicine, Unit of Nutritional Research, Umeå University, Umeå 90187, Sweden., Hartman CA; Department of Psychiatry, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands., Hassinen M; Kuopio Research Institute of Exercise Medicine, Kuopio, Finland., Hayward C; MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Edinburgh, EH4 2XU, Scotland, UK., Heikkilä K; Hjelt Institute Department of Public Health, University of Helsinki, FI-00014 Helsinki, Finland., Herzig KH; Institute of Biomedicine, University of Oulu, Oulu, Finland.; Medical Research Center Oulu and Oulu University Hospital, Oulu, Finland.; Biocenter Oulu, University of Oulu, FI-90014 Oulu, Finland., Helmer Q; Netherlands Consortium for Healthy Aging (NCHA), Leiden University Medical Center, Leiden 2300 RC, The Netherlands.; Department of Medical Statistics and Bioinformatics, Leiden University Medical Center, 2300 RC Leiden, The Netherlands.; Faculty of Psychology and Education, VU University Amsterdam, Amsterdam, The Netherlands., Hillege HL; Department of Cardiology, University Medical Center Groningen, University of Groningen, 9700RB Groningen, The Netherlands.; Department of Epidemiology, University Medical Center Groningen, University of Groningen, 9700 RB Groningen, The Netherlands., Holmen O; Department of Public Health and General Practice, Norwegian University of Science and Technology, Trondheim 7489, Norway., Hunt SC; Cardiovascular Genetics Division, Department of Internal Medicine, University of Utah, Salt Lake City, Utah 84108, USA., Isaacs A; Genetic Epidemiology Unit, Department of Epidemiology, Erasmus MC University Medical Center, 3015 GE Rotterdam, The Netherlands.; Center for Medical Sytems Biology, Leiden, The Netherlands., Ittermann T; Institute for Community Medicine, University Medicine Greifswald, D-17475 Greifswald, Germany., James AL; Department of Pulmonary Physiology and Sleep Medicine, Nedlands, Western Australia 6009, Australia.; School of Medicine and Pharmacology, University of Western Australia, Crawley 6009, Australia., Johansson I; Department of Odontology, Umeå University, Umeå 901 85, Sweden., Juliusdottir T; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK., Kalafati IP; Department of Dietetics-Nutrition, Harokopio University, Athens, Greece., Kinnunen L; National Institute for Health and Welfare, FI-00271 Helsinki, Finland., Koenig W; Department of Internal Medicine II, Ulm University Medical Centre, D-89081 Ulm, Germany., Kooner IK; Ealing Hospital NHS Trust, Middlesex UB1 3HW, UK., Kratzer W; Department of Internal Medicine I, Ulm University Medical Centre, D-89081 Ulm, Germany., Lamina C; Division of Genetic Epidemiology, Department of Medical Genetics, Molecular and Clinical Pharmacology, Innsbruck Medical University, 6020 Innsbruck, Austria., Leander K; Division of Cardiovascular Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden, Stockholm 17177, Sweden., Lee NR; USC-Office of Population Studies Foundation, Inc., University of San Carlos, Cebu City 6000, Philippines., Lichtner P; Institute of Human Genetics, Helmholtz Zentrum München - German Research Center for Environmental Health, D-85764 Neuherberg, Germany., Lind L; Department of Medical Sciences, Cardiovascular Epidemiology, Uppsala University, Uppsala 75185, Sweden., Lindström J; National Institute for Health and Welfare, FI-00271 Helsinki, Finland., Lobbens S; CNRS UMR 8199, F-59019 Lille, France.; European Genomic Institute for Diabetes, F-59000 Lille, France.; Université de Lille 2, F-59000 Lille, France., Lorentzon M; Centre for Bone and Arthritis Research, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg 413 45, Sweden., Mach F; Cardiology, Department of Specialties of Internal Medicine, Geneva University Hospital, Geneva 1211, Switzerland., Magnusson PK; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm 17177, Sweden., Mahajan A; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK., McArdle WL; School of Social and Community Medicine, University of Bristol, Bristol BS8 2BN, UK., Menni C; Department of Twin Research and Genetic Epidemiology, King's College London, London SE1 7EH, UK., Merger S; Division of Endocrinology, Diabetes and Metabolism, Ulm University Medical Centre, D-89081 Ulm, Germany., Mihailov E; Estonian Genome Center, University of Tartu, Tartu 51010, Estonia.; Institute of Molecular and Cell Biology, University of Tartu, Tartu 51010, Estonia., Milani L; Estonian Genome Center, University of Tartu, Tartu 51010, Estonia., Mills R; Ealing Hospital NHS Trust, Middlesex UB1 3HW, UK., Moayyeri A; Department of Twin Research and Genetic Epidemiology, King's College London, London SE1 7EH, UK.; Farr Institute of Health Informatics Research, University College London, London NW1 2DA, UK., Monda KL; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.; The Center for Observational Research, Amgen, Inc., Thousand Oaks, CA 91320, USA., Mooijaart SP; Netherlands Consortium for Healthy Aging (NCHA), Leiden University Medical Center, Leiden 2300 RC, The Netherlands.; Department of Gerontology and Geriatrics, Leiden University Medical Center, 2300 RC Leiden, The Netherlands., Mühleisen TW; Department of Genomics, Life & Brain Center, University of Bonn, Bonn, Germany.; Institute of Human Genetics, University of Bonn, Bonn, Germany., Mulas A; Istituto di Ricerca Genetica e Biomedica (IRGB), Consiglio Nazionale delle Ricerche, Cagliari, Sardinia 09042, Italy., Müller G; Center for Evidence-based Healthcare, University Hospital Carl Gustav Carus, Technische Universität Dresden, D-01307 Dresden, Germany., Müller-Nurasyid M; Institute of Genetic Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, D-85764 Neuherberg, Germany.; Department of Medicine I, University Hospital Grosshadern, Ludwig-Maximilians-Universität, D-81377 Munich, Germany.; Institute of Medical Informatics, Biometry and Epidemiology, Chair of Genetic Epidemiology, Ludwig-Maximilians-Universität, D-81377 Munich, Germany.; Deutsches Forschungszentrum für Herz-Kreislauferkrankungen (DZHK) (German Research Centre for Cardiovascular Research), Munich Heart Alliance, D-80636 Munich, Germany., Nagaraja R; Laboratory of Genetics, National Institute on Aging, Baltimore, MD 21224, USA., Nalls MA; Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, MD 20892, USA., Narisu N; Medical Genomics and Metabolic Genetics Branch, National Human Genome Research Institute, NIH, Bethesda, MD 20892, USA., Glorioso N; Hypertension and Related Diseases Centre - AOU, University of Sassari Medical School, Sassari 07100, Italy., Nolte IM; Department of Epidemiology, University Medical Center Groningen, University of Groningen, 9700 RB Groningen, The Netherlands., Olden M; Department of Genetic Epidemiology, Institute of Epidemiology and Preventive Medicine, University of Regensburg, D-93053 Regensburg, Germany., Rayner NW; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.; Wellcome Trust Sanger Institute, Hinxton, Cambridge CB10 1SA, UK.; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford OX3 7LJ, UK., Renstrom F; Department of Clinical Sciences, Genetic & Molecular Epidemiology Unit, Lund University Diabetes Center, Skåne University Hosptial, Malmö 205 02, Sweden., Ried JS; Institute of Genetic Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, D-85764 Neuherberg, Germany., Robertson NR; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford OX3 7LJ, UK., Rose LM; Division of Preventive Medicine, Brigham and Women's Hospital, Boston, MA 02215, USA., Sanna S; Istituto di Ricerca Genetica e Biomedica (IRGB), Consiglio Nazionale delle Ricerche, Cagliari, Sardinia 09042, Italy., Scharnagl H; Clinical Institute of Medical and Chemical Laboratory Diagnostics, Medical University of Graz, Graz 8036, Austria., Scholtens S; LifeLines Cohort Study, University Medical Center Groningen, University of Groningen, 9700 RB Groningen, The Netherlands., Sennblad B; Atherosclerosis Research Unit, Center for Molecular Medicine, Department of Medicine, Karolinska Institutet, Stockholm 17176, Sweden.; Science for Life Laboratory, Karolinska Institutet, Stockholm, Sweden., Seufferlein T; Department of Internal Medicine I, Ulm University Medical Centre, D-89081 Ulm, Germany., Sitlani CM; Department of Medicine, University of Washington, Seattle, WA 98101, USA., Smith AV; Icelandic Heart Association, Kopavogur 201, Iceland.; University of Iceland, Reykjavik 101, Iceland., Stirrups K; Wellcome Trust Sanger Institute, Hinxton, Cambridge CB10 1SA, UK.; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, EC1M 6BQ UK., Stringham HM; Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, MI 48109, USA., Sundström J; Department of Medical Sciences, Cardiovascular Epidemiology, Uppsala University, Uppsala 75185, Sweden., Swertz MA; Department of Genetics, University Medical Center Groningen, University of Groningen, 9700 RB Groningen, The Netherlands., Swift AJ; Medical Genomics and Metabolic Genetics Branch, National Human Genome Research Institute, NIH, Bethesda, MD 20892, USA., Syvänen AC; Science for Life Laboratory, Uppsala University, Uppsala 75185, Sweden.; Department of Medical Sciences, Molecular Medicine, Uppsala University, Uppsala 75144, Sweden., Tayo BO; Department of Public Health Sciences, Stritch School of Medicine, Loyola University of Chicago, Maywood, IL 61053, USA., Thorand B; German Center for Diabetes Research (DZD), Neuherberg, Germany.; Institute of Epidemiology II, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, Germany, D-85764 Neuherberg, Germany., Thorleifsson G; deCODE Genetics, Amgen inc., Reykjavik 101, Iceland., Tomaschitz A; Department of Cardiology, Medical University of Graz, Graz 8036, Austria., Troffa C; Hypertension and Related Diseases Centre - AOU, University of Sassari Medical School, Sassari 07100, Italy., van Oort FV; Department of Child and Adolescent Psychiatry, Psychology, Erasmus MC University Medical Centre, 3000 CB Rotterdam, The Netherlands., Verweij N; Department of Cardiology, University Medical Center Groningen, University of Groningen, 9700RB Groningen, The Netherlands., Vonk JM; Department of Epidemiology, University Medical Center Groningen, University of Groningen, 9700 RB Groningen, The Netherlands., Waite LL; HudsonAlpha Institute for Biotechnology, Huntsville, AL 35806, USA., Wennauer R; Department of Clinical Chemistry, Ulm University Medical Centre, D-89081 Ulm, Germany., Wilsgaard T; Department of Community Medicine, Faculty of Health Sciences, UiT The Arctic University of Norway, Tromsø, Norway., Wojczynski MK; Department of Genetics, Washington University School of Medicine, St. Louis, MO 63110, USA., Wong A; MRC Unit for Lifelong Health and Ageing at University College London, London WC1B 5JU, UK., Zhang Q; Department of Genetics, Washington University School of Medicine, St. Louis, MO 63110, USA., Zhao JH; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge Biomedical Campus, Cambridge, CB2 0QQ, UK., Brennan EP; Diabetes Complications Research Centre, Conway Institute, School of Medicine and Medical Sciences, University College Dublin, Dublin, Ireland., Choi M; Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul, Korea., Eriksson P; Atherosclerosis Research Unit, Center for Molecular Medicine, Department of Medicine, Karolinska Institutet, Stockholm 17176, Sweden., Folkersen L; Atherosclerosis Research Unit, Center for Molecular Medicine, Department of Medicine, Karolinska Institutet, Stockholm 17176, Sweden., Franco-Cereceda A; Cardiothoracic Surgery Unit, Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm 17176, Sweden., Gharavi AG; Department of Medicine, Columbia University College of Physicians and Surgeons, New York NY, USA., Hedman ÅK; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.; Science for Life Laboratory, Uppsala University, Uppsala 75185, Sweden.; Department of Medical Sciences, Molecular Epidemiology, Uppsala University, Uppsala 75185, Sweden., Hivert MF; Department of Population Medicine, Harvard Pilgrim Health Care Institute, Harvard Medical School, Boston, MA.; Massachusetts General Hospital, Boston, MA, USA., Huang J; State Key Laboratory of Medical Genomics, Shanghai Institute of Hematology, Rui Jin Hospital Affiliated with Shanghai Jiao Tong University School of Medicine, Shanghai, China.; Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA., Kanoni S; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, EC1M 6BQ UK., Karpe F; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford OX3 7LJ, UK.; NIHR Oxford Biomedical Research Centre, OUH Trust, Oxford OX3 7LE, UK., Keildson S; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK., Kiryluk K; Department of Medicine, Columbia University College of Physicians and Surgeons, New York NY, USA., Liang L; Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA.; Harvard School of Public Health, Department of Biostatistics, Harvard University, Boston, MA 2115, USA., Lifton RP; Department of Genetics, Howard Hughes Medical Institute, Yale University School of Medicine, New Haven, New Haven CT, USA., Ma B; Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA.; College of Information Science and Technology, Dalian Maritime University, Dalian, Liaoning 116026, China., McKnight AJ; Nephrology Research, Centre for Public Health, Queen's University of Belfast, Belfast, Co. Down BT9 7AB, UK., McPherson R; University of Ottawa Heart Institute, Ottawa K1Y 4W7, Canada., Metspalu A; Estonian Genome Center, University of Tartu, Tartu 51010, Estonia.; Institute of Molecular and Cell Biology, University of Tartu, Tartu 51010, Estonia., Min JL; School of Social and Community Medicine, University of Bristol, Bristol BS8 2BN, UK., Moffatt MF; National Heart and Lung Institute, Imperial College London, London SW3 6LY, UK., Montgomery GW; QIMR Berghofer Medical Research Institute, Brisbane, Queensland 4006, Australia., Murabito JM; National Heart, Lung, and Blood Institute, the Framingham Heart Study, Framingham MA 01702, USA.; Section of General Internal Medicine, Boston University School of Medicine, Boston, MA 02118, USA., Nicholson G; Department of Statistics, University of Oxford, 1 South Parks Road, Oxford OX1 3TG, UK.; MRC Harwell, Harwell Science and Innovation Campus, Harwell, UK., Nyholt DR; QIMR Berghofer Medical Research Institute, Brisbane, Queensland 4006, Australia.; Institute of Health and Biomedical Innovation, Queensland University of Technology, Brisbane, Queensland 4059, Australia., Olsson C; Cardiothoracic Surgery Unit, Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm 17176, Sweden., Perry JR; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.; Genetics of Complex Traits, University of Exeter Medical School, University of Exeter, Exeter EX1 2LU, UK.; Department of Twin Research and Genetic Epidemiology, King's College London, London SE1 7EH, UK., Reinmaa E; Estonian Genome Center, University of Tartu, Tartu 51010, Estonia., Salem RM; Divisions of Endocrinology and Genetics and Center for Basic and Translational Obesity Research, Boston Children's Hospital, Boston, MA 02115, USA.; Broad Institute of the Massachusetts Institute of Technology and Harvard University, Cambridge 02142, MA, USA.; Department of Genetics, Harvard Medical School, Boston, MA 02115, USA., Sandholm N; Department of Biomedical Engineering and Computational Science, Aalto University School of Science, Helsinki, Finland.; Department of Medicine, Division of Nephrology, Helsinki University Central Hospital, FI-00290 Helsinki, Finland.; Folkhälsan Institute of Genetics, Folkhälsan Research Center, FI-00290 Helsinki, Finland., Schadt EE; Icahn Institute for Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, NY 10580, USA., Scott RA; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge Biomedical Campus, Cambridge, CB2 0QQ, UK., Stolk L; Netherlands Consortium for Healthy Aging (NCHA), Leiden University Medical Center, Leiden 2300 RC, The Netherlands.; Department of Internal Medicine, Erasmus MC University Medical Center, 3015GE Rotterdam, The Netherlands., Vallejo EE; Computer Science Department, Tecnológico de Monterrey, Atizapán de Zaragoza, 52926, Mexico., Westra HJ; Department of Genetics, University Medical Center Groningen, University of Groningen, 9700 RB Groningen, The Netherlands., Zondervan KT; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.; Nuffield Department of Obstetrics & Gynaecology, University of Oxford, Oxford OX3 7BN, UK., Amouyel P; Institut Pasteur de Lille; INSERM, U744; Université de Lille 2; F-59000 Lille, France., Arveiler D; Department of Epidemiology and Public Health, EA3430, University of Strasbourg, Faculty of Medicine, Strasbourg, France., Bakker SJ; Department of Internal Medicine, University Medical Center Groningen, University of Groningen, 9700RB Groningen, The Netherlands., Beilby J; PathWest Laboratory Medicine of Western Australia, NEDLANDS, Western Australia 6009, Australia.; Pathology and Laboratory Medicine, The University of Western Australia, Perth, Western Australia 6009, Australia., Bergman RN; Cedars-Sinai Diabetes and Obesity Research Institute, Los Angeles, CA, USA., Blangero J; Department of Genetics, Texas Biomedical Research Institute, San Antonio, TX, USA., Brown MJ; Clinical Pharmacology Unit, University of Cambridge, Addenbrooke's Hospital, Hills Road, Cambridge CB2 2QQ, UK., Burnier M; Service of Nephrology, Department of Medicine, Lausanne University Hospital (CHUV), Lausanne 1005, Switzerland., Campbell H; Centre for Population Health Sciences, University of Edinburgh, Teviot Place, Edinburgh, EH8 9AG, Scotland, UK., Chakravarti A; Center for Complex Disease Genomics, McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA., Chines PS; Medical Genomics and Metabolic Genetics Branch, National Human Genome Research Institute, NIH, Bethesda, MD 20892, USA., Claudi-Boehm S; Division of Endocrinology, Diabetes and Metabolism, Ulm University Medical Centre, D-89081 Ulm, Germany., Collins FS; Medical Genomics and Metabolic Genetics Branch, National Human Genome Research Institute, NIH, Bethesda, MD 20892, USA., Crawford DC; Center for Human Genetics Research, Vanderbilt University Medical Center, Nashville TN 37203, USA.; Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN 37232, USA., Danesh J; Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., de Faire U; Division of Cardiovascular Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden, Stockholm 17177, Sweden., de Geus EJ; Biological Psychology, VU University Amsterdam, 1081BT Amsterdam, The Netherlands.; Institute for Research in Extramural Medicine, Institute for Health and Care Research, VU University, 1081BT Amsterdam, The Netherlands., Dörr M; Department of Internal Medicine B, University Medicine Greifswald, D-17475 Greifswald, Germany.; DZHK (Deutsches Zentrum für Herz-Kreislaufforschung - German Centre for Cardiovascular Research), partner site Greifswald, D-17475 Greifswald, Germany., Erbel R; Clinic of Cardiology, West-German Heart Centre, University Hospital Essen, Essen, Germany., Eriksson JG; National Institute for Health and Welfare, FI-00271 Helsinki, Finland.; Department of General Practice and Primary Health Care, University of Helsinki, FI-00290 Helsinki, Finland.; Unit of General Practice, Helsinki University Central Hospital, Helsinki 00290, Finland., Farrall M; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.; Division of Cardiovacular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford OX3 9DU, UK., Ferrannini E; Department of Internal Medicine, University of Pisa, Pisa, Italy.; National Research Council Institute of Clinical Physiology, University of Pisa, Pisa, Italy., Ferrières J; Department of Cardiology, Toulouse University School of Medicine, Rangueil Hospital, Toulouse, France., Forouhi NG; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge Biomedical Campus, Cambridge, CB2 0QQ, UK., Forrester T; UWI Solutions for Developing Countries, The University of the West Indies, Mona, Kingston 7, Jamaica., Franco OH; Netherlands Consortium for Healthy Aging (NCHA), 3015GE Rotterdam, The Netherlands.; Department of Epidemiology, Erasmus MC University Medical Center, 3015GE Rotterdam, The Netherlands., Gansevoort RT; Department of Internal Medicine, University Medical Center Groningen, University of Groningen, 9700RB Groningen, The Netherlands., Gieger C; Institute of Genetic Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, D-85764 Neuherberg, Germany., Gudnason V; Icelandic Heart Association, Kopavogur 201, Iceland.; University of Iceland, Reykjavik 101, Iceland., Haiman CA; Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA., Harris TB; Laboratory of Epidemiology and Population Sciences, National Institute on Aging, NIH, Bethesda, MD 20892, USA., Hattersley AT; Institute of Biomedical & Clinical Science, University of Exeter, Barrack Road, Exeter EX2 5DW, UK., Heliövaara M; National Institute for Health and Welfare, FI-00271 Helsinki, Finland., Hicks AA; Center for Biomedicine, European Academy Bozen, Bolzano (EURAC), Bolzano 39100, Italy - Affiliated Institute of the University of Lübeck, D-23562 Lübeck, Germany., Hingorani AD; Institute of Cardiovascular Science, University College London, London WC1E 6BT, UK., Hoffmann W; Institute for Community Medicine, University Medicine Greifswald, D-17475 Greifswald, Germany.; DZHK (Deutsches Zentrum für Herz-Kreislaufforschung - German Centre for Cardiovascular Research), partner site Greifswald, D-17475 Greifswald, Germany., Hofman A; Netherlands Consortium for Healthy Aging (NCHA), 3015GE Rotterdam, The Netherlands.; Department of Epidemiology, Erasmus MC University Medical Center, 3015GE Rotterdam, The Netherlands., Homuth G; Interfaculty Institute for Genetics and Functional Genomics, University Medicine Greifswald, D-17475 Greifswald, Germany., Humphries SE; Centre for Cardiovascular Genetics, Institute Cardiovascular Sciences, University College London, London WC1E 6JJ, UK., Hyppönen E; Sansom Institute for Health Research, University of South Australia, Adelaide 5000, South Australia, Australia.; School of Population Health, University of South Australia, Adelaide 5000, South Australia, Australia.; South Australian Health and Medical Research Institute, Adelaide, South Australia, Australia.; Population, Policy, and Practice, University College London Institute of Child Health, London WC1N 1EH, UK., Illig T; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, D-85764 Neuherberg, Germany.; Hannover Unified Biobank, Hannover Medical School, Hannover, D-30625 Hannover, Germany., Jarvelin MR; Department of Epidemiology and Biostatistics, Imperial College London, London W2 1PG, UK.; Biocenter Oulu, University of Oulu, FI-90014 Oulu, Finland.; National Institute for Health and Welfare, FI-90101 Oulu, Finland.; MRC Health Protection Agency (HPA) Centre for Environment and Health, School of Public Health, Imperial College London, UK.; Unit of Primary Care, Oulu University Hospital, FI-90220 Oulu, Finland.; Institute of Health Sciences, FI-90014 University of Oulu, Finland., Johansen B; Department of Biology, Norwegian University of Science and Technology, Trondheim, Norway., Jousilahti P; National Institute for Health and Welfare, FI-00271 Helsinki, Finland., Jula AM; National Institute for Health and Welfare, FI-00271 Helsinki, Finland., Kaprio J; National Institute for Health and Welfare, FI-00271 Helsinki, Finland.; Institute for Molecular Medicine, University of Helsinki, FI-00014 Helsinki, Finland.; Hjelt Institute Department of Public Health, University of Helsinki, FI-00014 Helsinki, Finland., Kee F; UK Clinical Research Collaboration Centre of Excellence for Public Health (NI), Queens University of Belfast, Belfast, Northern Ireland., Keinanen-Kiukaanniemi SM; Institute of Health Sciences, Faculty of Medicine, University of Oulu, Oulu, Finland.; Unit of Primary Health Care/General Practice, Oulu University Hospital, Oulu, Finland., Kooner JS; Ealing Hospital NHS Trust, Middlesex UB1 3HW, UK.; National Heart and Lung Institute, Imperial College London, London SW3 6LY, UK.; Imperial College Healthcare NHS Trust, London W12 0HS, UK., Kooperberg C; Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA., Kovacs P; Integrated Research and Treatment Center (IFB) Adiposity Diseases, University of Leipzig, D-04103 Leipzig, Germany.; Department of Medicine, University of Leipzig, D-04103 Leipzig, Germany., Kraja AT; Department of Genetics, Washington University School of Medicine, St. Louis, MO 63110, USA., Kumari M; Department of Epidemiology and Public Health, University College London, London WC1E 6BT, UK.; Department of Biological and Social Epidemiology, University of Essex, Wivenhoe Park, Colchester, Essex, CO4 3SQ, UK., Kuulasmaa K; National Institute for Health and Welfare, FI-00271 Helsinki, Finland., Kuusisto J; Department of Medicine, Kuopio University Hospital and University of Eastern Finland, FI-70210 Kuopio, Finland., Lakka TA; Kuopio Research Institute of Exercise Medicine, Kuopio, Finland.; Department of Physiology, Institute of Biomedicine, University of Eastern Finland, Kuopio Campus, Kuopio, Finland.; Department of Clinical Physiology and Nuclear Medicine, Kuopio University Hospital and University of Eastern Finland, Kuopio, Finland., Langenberg C; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge Biomedical Campus, Cambridge, CB2 0QQ, UK.; Department of Epidemiology and Public Health, University College London, London WC1E 6BT, UK., Le Marchand L; Epidemiology Program, University of Hawaii Cancer Center, Honolulu, HI USA., Lehtimäki T; Department of Clinical Chemistry, Fimlab Laboratories and School of Medicine University of Tampere, FI-33520 Tampere, Finland., Lyssenko V; Steno Diabetes Center A/S, Gentofte DK-2820, Denmark.; Lund University Diabetes Centre and Department of Clinical Science, Diabetes & Endocrinology Unit, Lund University, Malmö 221 00, Sweden., Männistö S; National Institute for Health and Welfare, FI-00271 Helsinki, Finland., Marette A; Institut Universitaire de Cardiologie et de Pneumologie de Québec, Faculty of Medicine, Laval University, Quebec, QC G1V 0A6, Canada.; Institute of Nutrition and Functional Foods, Laval University, Quebec, QC G1V 0A6, Canada., Matise TC; Department of Genetics, Rutgers University, Piscataway, NJ USA., McKenzie CA; UWI Solutions for Developing Countries, The University of the West Indies, Mona, Kingston 7, Jamaica., McKnight B; Department of Biostatistics, University of Washington, Seattle, WA 98195, USA., Musk AW; Department of Respiratory Medicine, Sir Charles Gairdner Hospital, Nedlands, Western Australia 6009, Australia., Möhlenkamp S; Clinic of Cardiology, West-German Heart Centre, University Hospital Essen, Essen, Germany., Morris AD; Medical Research Institute, University of Dundee, Ninewells Hospital and Medical School, Dundee DD1 9SY, UK., Nelis M; Estonian Genome Center, University of Tartu, Tartu 51010, Estonia., Ohlsson C; Centre for Bone and Arthritis Research, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg 413 45, Sweden., Oldehinkel AJ; Department of Psychiatry, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands., Ong KK; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge Biomedical Campus, Cambridge, CB2 0QQ, UK.; MRC Unit for Lifelong Health and Ageing at University College London, London WC1B 5JU, UK., Palmer LJ; Epidemiology and Obstetrics & Gynaecology, University of Toronto, Toronto, Ontario, Canada.; Genetic Epidemiology & Biostatistics Platform, Ontario Institute for Cancer Research, Toronto, Ontario M5G 0A3, Canada., Penninx BW; Institute for Research in Extramural Medicine, Institute for Health and Care Research, VU University, 1081BT Amsterdam, The Netherlands.; Department of Psychiatry, Neuroscience Campus, VU University Amsterdam, Amsterdam, The Netherlands., Peters A; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, D-85764 Neuherberg, Germany.; Deutsches Forschungszentrum für Herz-Kreislauferkrankungen (DZHK) (German Research Centre for Cardiovascular Research), Munich Heart Alliance, D-80636 Munich, Germany.; Institute of Epidemiology II, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, Germany, D-85764 Neuherberg, Germany., Pramstaller PP; Center for Biomedicine, European Academy Bozen, Bolzano (EURAC), Bolzano 39100, Italy - Affiliated Institute of the University of Lübeck, D-23562 Lübeck, Germany.; Department of Neurology, General Central Hospital, Bolzano 39100, Italy., Raitakari OT; Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, FI-20521 Turku, Finland.; Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, FI-20521 Turku, Finland., Rankinen T; Human Genomics Laboratory, Pennington Biomedical Research Center, Baton Rouge, LA 70808, USA., Rao DC; Department of Genetics, Washington University School of Medicine, St. Louis, MO 63110, USA.; Division of Biostatistics, Washington University School of Medicine, St. Louis, MO 63110, USA.; Department of Psychiatry, Washington University School of Medicine, St. Louis, MO 63110, USA., Rice TK; Division of Biostatistics, Washington University School of Medicine, St. Louis, MO 63110, USA.; Department of Psychiatry, Washington University School of Medicine, St. Louis, MO 63110, USA., Ridker PM; Division of Preventive Medicine, Brigham and Women's Hospital, Boston, MA 02215, USA.; Harvard Medical School, Boston, MA 02115, USA., Ritchie MD; Center for Systems Genomics, The Pennsylvania State University, University Park, PA 16802, USA., Rudan I; Center for Human Genetics Research, Vanderbilt University Medical Center, Nashville TN 37203, USA.; Croatian Centre for Global Health, Faculty of Medicine, University of Split, 21000 Split, Croatia., Salomaa V; National Institute for Health and Welfare, FI-00271 Helsinki, Finland., Samani NJ; Department of Cardiovascular Sciences, University of Leicester, Glenfield Hospital, Leicester LE3 9QP, UK.; National Institute for Health Research (NIHR) Leicester Cardiovascular Biomedical Research Unit, Glenfield Hospital, Leicester, LE3 9QP, UK., Saramies J; South Carelia Central Hospital, 53130 Lappeenranta, Finland., Sarzynski MA; Human Genomics Laboratory, Pennington Biomedical Research Center, Baton Rouge, LA 70808, USA., Schwarz PE; Department of Medicine III, University Hospital Carl Gustav Carus, Technische Universität Dresden, D-01307 Dresden, Germany.; Paul Langerhans Institute Dresden, German Center for Diabetes Research (DZD), Dresden, Germany., Shuldiner AR; Division of Endocrinology, Diabetes and Nutrition, University of Maryland School of Medicine, Baltimore, MD 21201, USA.; Program for Personalized and Genomic Medicine, University of Maryland School of Medicine, Baltimore, MD 21201, USA.; Geriatric Research and Education Clinical Center, Vetrans Administration Medical Center, Baltimore, MD 21201, USA., Staessen JA; Department of Epidemiology, Maastricht University, Maastricht, The Netherlands.; Research Unit Hypertension and Cardiovascular Epidemiology, KU Leuven Department of Cardiovascular Sciences, University of Leuven, B-3000 Leuven, Belgium., Steinthorsdottir V; deCODE Genetics, Amgen inc., Reykjavik 101, Iceland., Stolk RP; Department of Epidemiology, University Medical Center Groningen, University of Groningen, 9700 RB Groningen, The Netherlands., Strauch K; Institute of Genetic Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, D-85764 Neuherberg, Germany.; Institute of Medical Informatics, Biometry and Epidemiology, Chair of Genetic Epidemiology, Ludwig-Maximilians-Universität, D-81377 Munich, Germany., Tönjes A; Integrated Research and Treatment Center (IFB) Adiposity Diseases, University of Leipzig, D-04103 Leipzig, Germany.; Department of Medicine, University of Leipzig, D-04103 Leipzig, Germany., Tremblay A; Department of Kinesiology, Laval University, Quebec, QC G1V 0A6, Canada., Tremoli E; Dipartimento di Scienze Farmacologiche e Biomolecolari, Università di Milano & Centro Cardiologico Monzino, Instituto di Ricovero e Cura a Carattere Scientifico, Milan 20133, italy., Vohl MC; Institute of Nutrition and Functional Foods, Laval University, Quebec, QC G1V 0A6, Canada.; Department of Food Science and Nutrition, Laval University, Quebec, QC G1V 0A6, Canada., Völker U; Interfaculty Institute for Genetics and Functional Genomics, University Medicine Greifswald, D-17475 Greifswald, Germany.; DZHK (Deutsches Zentrum für Herz-Kreislaufforschung - German Centre for Cardiovascular Research), partner site Greifswald, D-17475 Greifswald, Germany., Vollenweider P; Department of Internal Medicine, University Hospital (CHUV) and University of Lausanne, 1011, Switzerland., Wilson JF; Centre for Population Health Sciences, University of Edinburgh, Teviot Place, Edinburgh, EH8 9AG, Scotland, UK., Witteman JC; Department of Epidemiology, Erasmus MC University Medical Center, 3015GE Rotterdam, The Netherlands., Adair LS; Department of Nutrition, University of North Carolina, Chapel Hill, NC 27599, USA., Bochud M; Institute of Social and Preventive Medicine (IUMSP), Centre Hospitalier Universitaire Vaudois and University of Lausanne, Lausanne, Switzerland.; Ministry of Health, Victoria, Republic of Seychelles., Boehm BO; Lee Kong Chian School of Medicine, Imperial College London and Nanyang Technological University, Singapore, 637553 Singapore, Singapore.; Department of Internal Medicine I, Ulm University Medical Centre, D-89081 Ulm, Germany., Bornstein SR; Department of Medicine III, University Hospital Carl Gustav Carus, Technische Universität Dresden, D-01307 Dresden, Germany., Bouchard C; Human Genomics Laboratory, Pennington Biomedical Research Center, Baton Rouge, LA 70808, USA., Cauchi S; CNRS UMR 8199, F-59019 Lille, France.; European Genomic Institute for Diabetes, F-59000 Lille, France.; Université de Lille 2, F-59000 Lille, France., Caulfield MJ; Clinical Pharmacology and Barts and The London Genome Centre, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, Charterhouse Square, London EC1M 6BQ, UK., Chambers JC; Ealing Hospital NHS Trust, Middlesex UB1 3HW, UK.; Department of Epidemiology and Biostatistics, Imperial College London, London W2 1PG, UK.; Imperial College Healthcare NHS Trust, London W12 0HS, UK., Chasman DI; Division of Preventive Medicine, Brigham and Women's Hospital, Boston, MA 02215, USA.; Harvard Medical School, Boston, MA 02115, USA., Cooper RS; Department of Public Health Sciences, Stritch School of Medicine, Loyola University of Chicago, Maywood, IL 61053, USA., Dedoussis G; Department of Dietetics-Nutrition, Harokopio University, Athens, Greece., Ferrucci L; Translational Gerontology Branch, National Institute on Aging, Baltimore MD 21225, USA., Froguel P; Department of Genomics of Common Disease, School of Public Health, Imperial College London, Hammersmith Hospital, London, UK.; CNRS UMR 8199, F-59019 Lille, France.; European Genomic Institute for Diabetes, F-59000 Lille, France.; Université de Lille 2, F-59000 Lille, France., Grabe HJ; Department of Psychiatry and Psychotherapy, University Medicine Greifswald, HELIOS-Hospital Stralsund, D-17475 Greifswald, Germany.; German Center for Neurodegenerative Diseases (DZNE), Rostock, Greifswald, D-17475 Greifswald, Germany., Hamsten A; Atherosclerosis Research Unit, Center for Molecular Medicine, Department of Medicine, Karolinska Institutet, Stockholm 17176, Sweden., Hui J; PathWest Laboratory Medicine of Western Australia, NEDLANDS, Western Australia 6009, Australia.; Pathology and Laboratory Medicine, The University of Western Australia, Perth, Western Australia 6009, Australia.; School of Population Health, The University of Western Australia, Nedlands, Western Australia 6009, Australia., Hveem K; Department of Public Health and General Practice, Norwegian University of Science and Technology, Trondheim 7489, Norway., Jöckel KH; Institute for Medical Informatics, Biometry and Epidemiology (IMIBE), University Hospital Essen, Essen, Germany., Kivimaki M; Department of Epidemiology and Public Health, University College London, London WC1E 6BT, UK., Kuh D; MRC Unit for Lifelong Health and Ageing at University College London, London WC1B 5JU, UK., Laakso M; Department of Medicine, Kuopio University Hospital and University of Eastern Finland, FI-70210 Kuopio, Finland., Liu Y; 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Department of Clinical Genetics, Erasmus MC University Medical Center, Rotterdam, The Netherlands., Palmer CN; Medical Research Institute, University of Dundee, Ninewells Hospital and Medical School, Dundee DD1 9SY, UK., Pedersen NL; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm 17177, Sweden., Perola M; Estonian Genome Center, University of Tartu, Tartu 51010, Estonia.; National Institute for Health and Welfare, FI-00271 Helsinki, Finland.; Institute for Molecular Medicine, University of Helsinki, FI-00014 Helsinki, Finland., Pérusse L; Institute of Nutrition and Functional Foods, Laval University, Quebec, QC G1V 0A6, Canada.; Department of Kinesiology, Laval University, Quebec, QC G1V 0A6, Canada., Peters U; Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA., Power C; Population, Policy, and Practice, University College London Institute of Child Health, London WC1N 1EH, UK., Quertermous T; Department of Medicine, Stanford University School of Medicine, Palo Alto, CA, USA., Rauramaa R; Kuopio Research Institute of Exercise Medicine, Kuopio, Finland.; Department of Clinical Physiology and Nuclear Medicine, Kuopio University Hospital and University of Eastern Finland, Kuopio, Finland., Rivadeneira F; Netherlands Consortium for Healthy Aging (NCHA), 3015GE Rotterdam, The Netherlands.; Department of Epidemiology, Erasmus MC University Medical Center, 3015GE Rotterdam, The Netherlands.; Department of Internal Medicine, Erasmus MC University Medical Center, 3015GE Rotterdam, The Netherlands., Saaristo TE; Finnish Diabetes Association, Kirjoniementie 15, FI-33680 Tampere, Finland.; Pirkanmaa Hospital District, Tampere, Finland., Saleheen D; Biological Psychology, VU University Amsterdam, 1081BT Amsterdam, The Netherlands.; Center for Non-Communicable Diseases, Karatchi, Pakistan.; Department of Medicine, University of Pennsylvania, Philadelphia, USA., Sinisalo J; Helsinki University Central Hospital Heart and Lung Center, Department of Medicine, Helsinki University Central Hospital, FI-00290 Helsinki, Finland., Slagboom PE; Netherlands Consortium for Healthy Aging (NCHA), Leiden University Medical Center, Leiden 2300 RC, The Netherlands.; Department of Molecular Epidemiology, Leiden University Medical Center, 2300 RC Leiden, The Netherlands., Snieder H; Department of Epidemiology, University Medical Center Groningen, University of Groningen, 9700 RB Groningen, The Netherlands., Spector TD; Department of Twin Research and Genetic Epidemiology, King's College London, London SE1 7EH, UK., Stefansson K; deCODE Genetics, Amgen inc., Reykjavik 101, Iceland.; Faculty of Medicine, University of Iceland, Reykjavik 101, Iceland., Stumvoll M; Integrated Research and Treatment Center (IFB) Adiposity Diseases, University of Leipzig, D-04103 Leipzig, Germany.; Department of Medicine, University of Leipzig, D-04103 Leipzig, Germany., Tuomilehto J; National Institute for Health and Welfare, FI-00271 Helsinki, Finland.; Instituto de Investigacion Sanitaria del Hospital Universario LaPaz (IdiPAZ), Madrid, Spain.; Diabetes Research Group, King Abdulaziz University, 21589 Jeddah, Saudi Arabia.; 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Institute of Cellular Medicine, Newcastle University, Newcastle NE1 7RU, UK., Wareham NJ; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge Biomedical Campus, Cambridge, CB2 0QQ, UK., Watkins H; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.; Division of Cardiovacular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford OX3 9DU, UK., Wichmann HE; Institute of Medical Informatics, Biometry and Epidemiology, Chair of Epidemiology, Ludwig-Maximilians-Universität, D-85764 Munich, Germany.; Klinikum Grosshadern, D-81377 Munich, Germany.; Institute of Epidemiology I, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, Germany, D-85764 Neuherberg, Germany., Abecasis GR; Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, MI 48109, USA., Assimes TL; Department of Medicine, Stanford University School of Medicine, Palo Alto, CA, USA., Berndt SI; Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA., Boehnke M; Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, MI 48109, USA., Borecki IB; Department of Genetics, Washington University School of Medicine, St. Louis, MO 63110, USA., Deloukas P; Wellcome Trust Sanger Institute, Hinxton, Cambridge CB10 1SA, UK.; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, EC1M 6BQ UK.; Princess Al-Jawhara Al-Brahim Centre of Excellence in Research of Hereditary Disorders (PACER-HD), King Abdulaziz University, 21589 Jeddah, Saudi Arabia., Franke L; Department of Genetics, University Medical Center Groningen, University of Groningen, 9700 RB Groningen, The Netherlands., Frayling TM; Genetics of Complex Traits, University of Exeter Medical School, University of Exeter, Exeter EX1 2LU, UK., Groop LC; Institute for Molecular Medicine, University of Helsinki, FI-00014 Helsinki, Finland.; Lund University Diabetes Centre and Department of Clinical Science, Diabetes & Endocrinology Unit, Lund University, Malmö 221 00, Sweden., Hunter DJ; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA.; Department of Nutrition, Harvard School of Public Health, Boston, MA, USA.; Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA., Kaplan RC; Albert Einstein College of Medicine. Department of Epidemiology and Population Health, Belfer 1306, NY 10461, USA., O'Connell JR; Division of Endocrinology, Diabetes and Nutrition, University of Maryland School of Medicine, Baltimore, MD 21201, USA.; Program for Personalized and Genomic Medicine, University of Maryland School of Medicine, Baltimore, MD 21201, USA., Qi L; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA.; Department of Nutrition, Harvard School of Public Health, Boston, MA, USA., Schlessinger D; Laboratory of Genetics, National Institute on Aging, Baltimore, MD 21224, USA., Strachan DP; Division of Population Health Sciences & Education, St George's, University of London, London SW17 0RE, UK., Thorsteinsdottir U; deCODE Genetics, Amgen inc., Reykjavik 101, Iceland.; Faculty of Medicine, University of Iceland, Reykjavik 101, Iceland., van Duijn CM; Genetic Epidemiology Unit, Department of Epidemiology, Erasmus MC University Medical Center, 3015 GE Rotterdam, The Netherlands.; 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Broad Institute of the Massachusetts Institute of Technology and Harvard University, Cambridge 02142, MA, USA.; Department of Genetics, Harvard Medical School, Boston, MA 02115, USA., Zillikens MC; Netherlands Consortium for Healthy Aging (NCHA), 3015GE Rotterdam, The Netherlands.; Department of Internal Medicine, Erasmus MC University Medical Center, 3015GE Rotterdam, The Netherlands., McCarthy MI; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford OX3 7LJ, UK.; Oxford NIHR Biomedical Research Centre, Oxford University Hospitals NHS Trust, Oxford, OX3 7LJ, UK., Speliotes EK; Department of Internal Medicine, Division of Gastroenterology, and Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI 48109., North KE; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.; Carolina Center for Genome Sciences, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA., Fox CS; National Heart, Lung, and Blood Institute, the Framingham Heart Study, Framingham MA 01702, USA., Barroso I; Wellcome Trust Sanger Institute, Hinxton, Cambridge CB10 1SA, UK.; University of Cambridge Metabolic Research Laboratories, Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge CB2 OQQ, UK.; NIHR Cambridge Biomedical Research Centre, Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge CB2 OQQ, UK., Franks PW; Department of Public Health and Clinical Medicine, Unit of Medicine, Umeå University, Umeå 901 87, Sweden.; Department of Clinical Sciences, Genetic & Molecular Epidemiology Unit, Lund University Diabetes Center, Skåne University Hosptial, Malmö 205 02, Sweden.; Department of Nutrition, Harvard School of Public Health, Boston, MA, USA., Ingelsson E; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.; Science for Life Laboratory, Uppsala University, Uppsala 75185, Sweden.; Department of Medical Sciences, Molecular Epidemiology, Uppsala University, Uppsala 75185, Sweden., Heid IM; Department of Genetic Epidemiology, Institute of Epidemiology and Preventive Medicine, University of Regensburg, D-93053 Regensburg, Germany.; Institute of Genetic Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, D-85764 Neuherberg, Germany., Loos RJ; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge Biomedical Campus, Cambridge, CB2 0QQ, UK.; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.; The Genetics of Obesity and Related Metabolic Traits Program, The Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.; The Mindich Child Health and Development Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Cupples LA; Department of Biostatistics, Boston University School of Public Health, Boston, MA 02118, USA.; National Heart, Lung, and Blood Institute, the Framingham Heart Study, Framingham MA 01702, USA., Morris AP; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.; Estonian Genome Center, University of Tartu, Tartu 51010, Estonia.; Department of Biostatistics, University of Liverpool, Liverpool L69 3GA, UK., Lindgren CM; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.; Broad Institute of the Massachusetts Institute of Technology and Harvard University, Cambridge 02142, MA, USA., Mohlke KL; Department of Genetics, University of North Carolina, Chapel Hill, NC 27599, USA.
Publikováno v:
Nature [Nature] 2015 Feb 12; Vol. 518 (7538), pp. 187-196.
Autor:
Mahajan A; Wellcome Trust Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom., Sim X; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, Michigan, United States of America., Ng HJ; Oxford Centre for Diabetes, Endocrinology and Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, United Kingdom., Manning A; Program in Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts, United States of America., Rivas MA; Wellcome Trust Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom., Highland HM; Human Genetics Center, The University of Texas Graduate School of Biomedical Sciences at Houston, The University of Texas Health Science Center at Houston, Houston, Texas, United States of America., Locke AE; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, Michigan, United States of America., Grarup N; The Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Im HK; Department of Health Studies, Biostatistics Laboratory, The University of Chicago, Chicago, Illinois, United States of America., Cingolani P; School of Computer Science, McGill University, Montreal, Quebec, Canada; McGill University and Génome Québec Innovation Centre, Montreal, Quebec, Canada., Flannick J; Program in Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts, United States of America; Department of Molecular Biology, Massachusetts General Hospital, Boston, Massachusetts, United States of America., Fontanillas P; Program in Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts, United States of America., Fuchsberger C; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, Michigan, United States of America., Gaulton KJ; Wellcome Trust Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom., Teslovich TM; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, Michigan, United States of America., Rayner NW; Wellcome Trust Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom; Oxford Centre for Diabetes, Endocrinology and Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, United Kingdom; Department of Human Genetics, Wellcome Trust Sanger Institute, Hinxton, Cambridgeshire, United Kingdom., Robertson NR; Wellcome Trust Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom; Oxford Centre for Diabetes, Endocrinology and Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, United Kingdom., Beer NL; Oxford Centre for Diabetes, Endocrinology and Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, United Kingdom., Rundle JK; Oxford Centre for Diabetes, Endocrinology and Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, United Kingdom., Bork-Jensen J; The Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Ladenvall C; Department of Clinical Sciences, Diabetes and Endocrinology, Lund University Diabetes Centre, Malmö, Sweden., Blancher C; High Throughput Genomics, Oxford Genomics Centre, Wellcome Trust Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom., Buck D; High Throughput Genomics, Oxford Genomics Centre, Wellcome Trust Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom., Buck G; High Throughput Genomics, Oxford Genomics Centre, Wellcome Trust Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom., Burtt NP; Program in Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts, United States of America., Gabriel S; Program in Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts, United States of America., Gjesing AP; The Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Groves CJ; Oxford Centre for Diabetes, Endocrinology and Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, United Kingdom., Hollensted M; The Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Huyghe JR; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, Michigan, United States of America., Jackson AU; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, Michigan, United States of America., Jun G; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, Michigan, United States of America., Justesen JM; The Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Mangino M; Department of Twin Research and Genetic Epidemiology, King's College London, London, United Kingdom., Murphy J; Program in Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts, United States of America., Neville M; Oxford Centre for Diabetes, Endocrinology and Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, United Kingdom., Onofrio R; Program in Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts, United States of America., Small KS; Department of Twin Research and Genetic Epidemiology, King's College London, London, United Kingdom., Stringham HM; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, Michigan, United States of America., Syvänen AC; Department of Medical Sciences, Molecular Medicine and Science for Life Laboratory, Uppsala University, Uppsala, Sweden., Trakalo J; High Throughput Genomics, Oxford Genomics Centre, Wellcome Trust Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom., Abecasis G; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, Michigan, United States of America., Bell GI; Departments of Medicine and Human Genetics, The University of Chicago, Chicago, Illinois, United States of America., Blangero J; Department of Genetics, Texas Biomedical Research Institute, San Antonio, Texas, United States of America., Cox NJ; Department of Medicine, Section of Genetic Medicine, The University of Chicago, Chicago, Illinois, United States of America., Duggirala R; Department of Genetics, Texas Biomedical Research Institute, San Antonio, Texas, United States of America., Hanis CL; Human Genetics Center, School of Public Health, The University of Texas Health Science Center at Houston, Houston, Texas, United States of America., Seielstad M; Blood Systems Research Institute, San Francisco, California, United States of America; Department of Laboratory Medicine & Institute for Human Genetics, University of California, San Francisco, San Francisco, California, United States of America., Wilson JG; Department of Physiology and Biophysics, University of Mississippi Medical Center, Jackson, Mississippi, United States of America., Christensen C; Department of Internal Medicine and Endocrinology, Vejle Hospital, Vejle, Denmark., Brandslund I; Department of Clinical Biochemistry, Vejle Hospital, Vejle, Denmark; Institute of Regional Health Research, University of Southern Denmark, Odense, Denmark., Rauramaa R; Foundation for Research in Health, Exercise and Nutrition, Kuopio Research Institute of Exercise Medicine, Kuopio, Finland., Surdulescu GL; Department of Twin Research and Genetic Epidemiology, King's College London, London, United Kingdom., Doney AS; Division of Cardiovascular and Diabetes Medicine, Medical Research Institute, Ninewells Hospital and Medical School, Dundee, United Kingdom., Lannfelt L; Department of Public Health and Caring Sciences, Geriatrics, Uppsala University, Uppsala, Sweden., Linneberg A; Department of Clinical Experimental Research, Glostrup University Hospital, Glostrup, Denmark; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark; Research Centre for Prevention and Health, Glostrup University Hospital, Glostrup, Denmark., Isomaa B; Department of Social Services and Health Care, Jakobstad, Finland; Folkhälsan Research Centre, Helsinki, Finland., Tuomi T; Folkhälsan Research Centre, Helsinki, Finland; Department of Endocrinology, Helsinki University Central Hospital, Helsinki, Finland., Jørgensen ME; Steno Diabetes Center, Gentofte, Denmark., Jørgensen T; Research Centre for Prevention and Health, Glostrup University Hospital, Glostrup, Denmark; Faculty of Medicine, University of Aalborg, Aalborg, Denmark., Kuusisto J; Faculty of Health Sciences, Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland, Kuopio, Finland; Kuopio University Hospital, Kuopio, Finland., Uusitupa M; Institute of Public Health and Clinical Nutrition, University of Eastern Finland, Kuopio, Finland., Salomaa V; National Institute for Health and Welfare, Helsinki, Finland., Spector TD; Department of Twin Research and Genetic Epidemiology, King's College London, London, United Kingdom., Morris AD; Clinical Research Centre, Centre for Molecular Medicine, Ninewells Hospital and Medical School, Dundee, United Kingdom., Palmer CN; Pat Macpherson Centre for Pharmacogenetics and Pharmacogenomics, Medical Research Institute, Ninewells Hospital and Medical School, Dundee, United Kingdom., Collins FS; Medical Genomics and Metabolic Genetics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland, United States of America., Mohlke KL; Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America., Bergman RN; Cedars-Sinai Diabetes and Obesity Research Institute, Los Angeles, California, United States of America., Ingelsson E; Wellcome Trust Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom; Department of Medical Sciences, Molecular Epidemiology and Science for Life Laboratory, Uppsala University, Uppsala, Sweden., Lind L; Department of Medical Sciences, Uppsala University, Uppsala, Sweden., Tuomilehto J; Diabetes Research Group, King Abdulaziz University, Jeddah, Saudi Arabia; Instituto de Investigacion Sanitaria del Hospital Universario LaPaz (IdiPAZ), University Hospital LaPaz, Autonomous University of Madrid, Madrid, Spain; Center for Vascular Prevention, Danube University Krems, Krems, Austria; Diabetes Prevention Unit, National Institute for Health and Welfare, Helsinki, Finland., Hansen T; The Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark; Faculty of Health Sciences, University of Southern Denmark, Odense, Denmark., Watanabe RM; Department of Physiology & Biophysics, Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America; Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America; Diabetes and Obesity Research Institute, Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America., Prokopenko I; Wellcome Trust Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom; Oxford Centre for Diabetes, Endocrinology and Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, United Kingdom; Department of Genomics of Common Disease, School of Public Health, Imperial College London, London, United Kingdom., Dupuis J; National Heart, Lung, and Blood Institute's Framingham Heart Study, Framingham, Massachusetts, United States of America; Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, United States of America., Karpe F; Oxford Centre for Diabetes, Endocrinology and Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, United Kingdom; Oxford NIHR Biomedical Research Centre, Oxford University Hospitals Trust, Oxford, United Kingdom., Groop L; Department of Clinical Sciences, Diabetes and Endocrinology, Lund University Diabetes Centre, Malmö, Sweden., Laakso M; Faculty of Health Sciences, Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland, Kuopio, Finland; Kuopio University Hospital, Kuopio, Finland., Pedersen O; The Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Florez JC; Program in Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts, United States of America; Diabetes Research Center (Diabetes Unit), Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts, United States of America; Department of Medicine, Harvard Medical School, Boston, Massachusetts, United States of America; Center for Human Genetic Research, Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts, United States of America., Morris AP; Wellcome Trust Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom; Department of Biostatistics, University of Liverpool, Liverpool, United Kingdom; Estonian Genome Centre, University of Tartu, Tartu, Estonia., Altshuler D; Program in Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts, United States of America; Department of Molecular Biology, Massachusetts General Hospital, Boston, Massachusetts, United States of America; Diabetes Research Center (Diabetes Unit), Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts, United States of America; Department of Medicine, Harvard Medical School, Boston, Massachusetts, United States of America; Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America; Department of Genetics, Harvard Medical School, Boston, Massachusetts, United States of America., Meigs JB; General Medicine Division, Massachusetts General Hospital and Department of Medicine, Harvard Medical School, Boston, Massachusetts, United States of America., Boehnke M; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, Michigan, United States of America., McCarthy MI; Wellcome Trust Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom; Oxford Centre for Diabetes, Endocrinology and Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, United Kingdom; Oxford NIHR Biomedical Research Centre, Oxford University Hospitals Trust, Oxford, United Kingdom., Lindgren CM; Wellcome Trust Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom; Program in Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts, United States of America., Gloyn AL; Oxford Centre for Diabetes, Endocrinology and Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, United Kingdom; Oxford NIHR Biomedical Research Centre, Oxford University Hospitals Trust, Oxford, United Kingdom.
Publikováno v:
PLoS genetics [PLoS Genet] 2015 Jan 27; Vol. 11 (1), pp. e1004876. Date of Electronic Publication: 2015 Jan 27 (Print Publication: 2015).
Autor:
Hruby A; Tufts University Friedman School of Nutrition Science and Policy, Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University, Boston, MA, USA., Ngwa JS, Renström F, Wojczynski MK, Ganna A, Hallmans G, Houston DK, Jacques PF, Kanoni S, Lehtimäki T, Lemaitre RN, Manichaikul A, North KE, Ntalla I, Sonestedt E, Tanaka T, van Rooij FJ, Bandinelli S, Djoussé L, Grigoriou E, Johansson I, Lohman KK, Pankow JS, Raitakari OT, Riserus U, Yannakoulia M, Zillikens MC, Hassanali N, Liu Y, Mozaffarian D, Papoutsakis C, Syvänen AC, Uitterlinden AG, Viikari J, Groves CJ, Hofman A, Lind L, McCarthy MI, Mikkilä V, Mukamal K, Franco OH, Borecki IB, Cupples LA, Dedoussis GV, Ferrucci L, Hu FB, Ingelsson E, Kähönen M, Kao WH, Kritchevsky SB, Orho-Melander M, Prokopenko I, Rotter JI, Siscovick DS, Witteman JC, Franks PW, Meigs JB, McKeown NM, Nettleton JA
Publikováno v:
The Journal of nutrition [J Nutr] 2013 Mar; Vol. 143 (3), pp. 345-53. Date of Electronic Publication: 2013 Jan 23.
Autor:
Ingelsson E; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden. erik.ingelsson@ki.se, Langenberg C, Hivert MF, Prokopenko I, Lyssenko V, Dupuis J, Mägi R, Sharp S, Jackson AU, Assimes TL, Shrader P, Knowles JW, Zethelius B, Abbasi FA, Bergman RN, Bergmann A, Berne C, Boehnke M, Bonnycastle LL, Bornstein SR, Buchanan TA, Bumpstead SJ, Böttcher Y, Chines P, Collins FS, Cooper CC, Dennison EM, Erdos MR, Ferrannini E, Fox CS, Graessler J, Hao K, Isomaa B, Jameson KA, Kovacs P, Kuusisto J, Laakso M, Ladenvall C, Mohlke KL, Morken MA, Narisu N, Nathan DM, Pascoe L, Payne F, Petrie JR, Sayer AA, Schwarz PE, Scott LJ, Stringham HM, Stumvoll M, Swift AJ, Syvänen AC, Tuomi T, Tuomilehto J, Tönjes A, Valle TT, Williams GH, Lind L, Barroso I, Quertermous T, Walker M, Wareham NJ, Meigs JB, McCarthy MI, Groop L, Watanabe RM, Florez JC
Publikováno v:
Diabetes [Diabetes] 2010 May; Vol. 59 (5), pp. 1266-75. Date of Electronic Publication: 2010 Feb 25.
Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge.
Autor:
Saxena R; Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, Massachusetts, USA., Hivert MF, Langenberg C, Tanaka T, Pankow JS, Vollenweider P, Lyssenko V, Bouatia-Naji N, Dupuis J, Jackson AU, Kao WH, Li M, Glazer NL, Manning AK, Luan J, Stringham HM, Prokopenko I, Johnson T, Grarup N, Boesgaard TW, Lecoeur C, Shrader P, O'Connell J, Ingelsson E, Couper DJ, Rice K, Song K, Andreasen CH, Dina C, Köttgen A, Le Bacquer O, Pattou F, Taneera J, Steinthorsdottir V, Rybin D, Ardlie K, Sampson M, Qi L, van Hoek M, Weedon MN, Aulchenko YS, Voight BF, Grallert H, Balkau B, Bergman RN, Bielinski SJ, Bonnefond A, Bonnycastle LL, Borch-Johnsen K, Böttcher Y, Brunner E, Buchanan TA, Bumpstead SJ, Cavalcanti-Proença C, Charpentier G, Chen YD, Chines PS, Collins FS, Cornelis M, J Crawford G, Delplanque J, Doney A, Egan JM, Erdos MR, Firmann M, Forouhi NG, Fox CS, Goodarzi MO, Graessler J, Hingorani A, Isomaa B, Jørgensen T, Kivimaki M, Kovacs P, Krohn K, Kumari M, Lauritzen T, Lévy-Marchal C, Mayor V, McAteer JB, Meyre D, Mitchell BD, Mohlke KL, Morken MA, Narisu N, Palmer CN, Pakyz R, Pascoe L, Payne F, Pearson D, Rathmann W, Sandbaek A, Sayer AA, Scott LJ, Sharp SJ, Sijbrands E, Singleton A, Siscovick DS, Smith NL, Sparsø T, Swift AJ, Syddall H, Thorleifsson G, Tönjes A, Tuomi T, Tuomilehto J, Valle TT, Waeber G, Walley A, Waterworth DM, Zeggini E, Zhao JH, Illig T, Wichmann HE, Wilson JF, van Duijn C, Hu FB, Morris AD, Frayling TM, Hattersley AT, Thorsteinsdottir U, Stefansson K, Nilsson P, Syvänen AC, Shuldiner AR, Walker M, Bornstein SR, Schwarz P, Williams GH, Nathan DM, Kuusisto J, Laakso M, Cooper C, Marmot M, Ferrucci L, Mooser V, Stumvoll M, Loos RJ, Altshuler D, Psaty BM, Rotter JI, Boerwinkle E, Hansen T, Pedersen O, Florez JC, McCarthy MI, Boehnke M, Barroso I, Sladek R, Froguel P, Meigs JB, Groop L, Wareham NJ, Watanabe RM
Publikováno v:
Nature genetics [Nat Genet] 2010 Feb; Vol. 42 (2), pp. 142-8. Date of Electronic Publication: 2010 Jan 17.
Autor:
Nelson,CP, Hamby,SE, Saleheen,D, Hopewell,JC, Zeng,L, Assimes,TL, Kanoni,S, Willenborg,C, Burgess,S, Amouyel,P, Anand,S, Blankenberg,S, Boehm,BO, Clarke,RJ, Collins,R, Dedoussis,G, Farrall,M, Franks,PW, Groop,L, Hall,AS, Hamsten,A, Hengstenberg,C, Hovingh,GK, Ingelsson,E, Kathiresan,S, Kee,F, König,IR, Kooner,J, Lehtimäki,T, März,W, McPherson,R, Metspalu,A, Nieminen,MS, O'Donnell,CJ, Palmer,CN, Peters,A, Perola,M, Reilly,MP, Ripatti,S, Roberts,R, Salomaa,V, Shah,SH, Schreiber,S, Siegbahn,A, Thorsteinsdottir,U, Veronesi,G, Wareham,N, Willer,CJ, Zalloua,PA, Erdmann,J, Deloukas,P, Watkins,H, Schunkert,H, Danesh,J, Thompson,JR, Samani,NJ, Assimes,T, Goldstein,BA, Stirrups,K, Cazier,JB, Johansson,Å, Lee,JY, Chambers,JC, Esko,T, Folkersen,L, Goel,A, Grundberg,E, Havulinna,AS, Ho,WK, Eriksson,N, Kleber,ME, Kristiansson,K, Lundmark,P, Lyytikäinen,LP, Rafelt,S, Shungin,D, Strawbridge,RJ, Thorleifsson,G, Tikkanen,E, Van, Zuydam, N, Voight,BF, Waite,LL, Zhang,W, Ziegler,A, Absher,D, Altshuler,D, Balmforth,AJ, Barroso,I, Braund,PS, Burgdorf,C, Claudi Boehm,S, Cox,D, Dimitriou,M, Do,R, Doney,AS, El, Mokhtari, Eriksson,P, Fischer,K, Fontanillas,P, Franco Cereceda,A, Gigante,B, Gustafsson,S, Hager,J, Hallmans,G, Han,BG, Hunt,SE, Kang,HM, Illig,T, Kessler,T, Knowles,JW, Kolovou,G, Kuusisto,J, Langenberg,C, Langford,C, Leander,K, Lokki,ML, Lundmark,A, McCarthy,MI, Meisinger,C, Melander,O, Mihailov,E, Maouche,S, Morris,AD, Müller Nurasyid,M, Nikus,K, Peden,JF, Rayner,NW, Rasheed,A, Rosinger,S, Rubin,D, Rumpf,MP, Schäfer,A, Sivananthan,M, Song,C, Stewart,AF, Tan,ST, Thorgeirsson,G, van, der, Schoot, CE, Wagner,PJ, Wells,GA, Wild,PS, Yang,TP, Arveiler,D, Basart,H, Boehnke,M, Boerwinkle,E, BRAMBILLA, PAOLO, Cambien,F, Cupples,AL, de, Faire, U, Dehghan,A, Diemert,P, Epstein,SE, Evans,A, Ferrario,MM, Ferrières,J, Gauguier,D, Go,AS, Goodall,AH, Gudnason,V, Hazen,SL, Holm,H, Iribarren,C, Jang,Y, Kähönen,M, Kim,HS, Klopp,N, Koenig,W, Kratzer,W, Kuulasmaa,K, Laakso,M, Laaksonen,R, Lind,L, Ouwehand,WH, Parish,S, Park,JE, Pedersen,NL, Quertermous,T, Rader,DJ, Schadt,E, Sinisalo,J, Stark,K, Stefansson,K, Trégouët,DA, Virtamo,J, Wallentin,L, Zimmermann,ME, Sandhu,MS, Pastinen,T, Syvänen,AC, Blankenberg,SS, Clarke,R, O'Donnell,C, Kooner,JS
Publikováno v:
New England Journal of Medicine; 372(17), pp 1608-1618 (2015)
New England journal of medicine, 372(17), 1608-1618. Massachussetts Medical Society
New England journal of medicine, 372(17), 1608-1618. Massachussetts Medical Society
BACKGROUND: The nature and underlying mechanisms of an inverse association between adult height and the risk of coronary artery disease (CAD) are unclear. METHODS: We used a genetic approach to investigate the association between height and CAD, usin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34f7f0cf42b8ea318d0434af2586dc6a
https://lup.lub.lu.se/record/5386538
https://lup.lub.lu.se/record/5386538
Autor:
Strawbridge, Rj, Dupuis, J, Prokopenko, I, Barker, A, Ahlqvist, E, Rybin, D, Petrie, Jr, Travers, Me, Bouatia Naji, N, Dimas, As, Nica, A, Wheeler, E, Chen, H, Voight, Bf, Taneera, J, Kanoni, S, Peden, Jf, Turrini, F, Gustafsson, S, Zabena, C, Almgren, P, Barker, Dj, Barnes, D, Dennison, Em, Eriksson, Jg, Eriksson, P, Eury, E, Folkersen, L, Fox, Cs, Frayling, Tm, Goel, A, Gu, Hf, Horikoshi, M, Isomaa, B, Jackson, Au, Jameson, Ka, Kajantie, E, Kerr Conte, J, Kuulasmaa, T, Kuusisto, J, Loos, Rj, Luan, J, Makrilakis, K, Manning, Ak, Martínez Larrad MT, Narisu, N, Nastase Mannila, M, Ohrvik, J, Osmond, C, Pascoe, L, Payne, F, Sayer, Aa, Sennblad, B, Silveira, A, Stancáková, A, Stirrups, K, Swift, Aj, Syvänen, Ac, Tuomi, T, van 't Hooft FM, Walker, M, Weedon, Mn, Xie, W, Zethelius, B, Diagram, Consortium, Giant, Consortium, Muther, Consortium, Cardiogram, Consortium, C4d, Consortium, Ongen, H, Mälarstig, A, Hopewell, Jc, Saleheen, D, Chambers, J, Parish, S, Danesh, J, Kooner, J, Ostenson, Cg, Lind, L, Cooper, Cc, Serrano Ríos, M, Ferrannini, E, Forsen, Tj, Clarke, R, Franzosi, Mg, Seedorf, U, Watkins, H, Froguel, P, Johnson, P, Deloukas, P, Collins, Fs, Laakso, M, Dermitzakis, Et, Boehnke, M, Mccarthy, Mi, Wareham, Nj, Groop, L, Pattou, F, Gloyn, Al, Dedoussis, Gv, Lyssenko, V, Meigs, Jb, Barroso, I, Watanabe, Rm, Ingelsson, E, Langenberg, C, Hamsten, A, Voight BF, Florez J. C., Scott, Lj, Steinthorsdottir, V, Morris, Ap, Dina, C, Welch, Rp, Zeggini, E, Huth, C, Aulchenko, Ys, Thorleifsson, G, Mcculloch, Lj, Ferreira, T, Grallert, H, Amin, N, Wu, G, Willer, Cj, Raychaudhuri, S, Mccarroll, Sa, Hofmann, Om, Qi, L, Segrè, Av, van Hoek, M, Navarro, P, Ardlie, K, Balkau, B, Benediktsson, R, Bennett, Aj, Blagieva, R, Boerwinkle, E, Bonnycastle, Ll, Bengtsson Boström, K, Bravenboer, B, Bumpstead, S, Burtt, P, Charpentier, G, Chines, Ps, Cornelis, M, Couper, Dj, Crawford, G, Doney, As, Elliott, Ks, Elliott, Al, Erdos, Mr, Franklin, Cs, Gieger, C, Grarup, N, Green, T, Griffin, S, Groves, Cj, Guiducci, C, Hadjadj, S, Hassanali, N, Herder, C, Johnson, Pr, Jørgensen, T, Kao, Wh, Klopp, N, Kong, A, Kraft, P, Lauritzen, T, Li, M, Lieverse, A, Lindgren, Cm, Marre, M, Meitinger, T, Midthjell, K, Morken, Ma, Nilsson, P, Owen, Kr, Perry, Jr, Petersen, K, Platou, C, Proença, C, Rathmann, W, William Rayner, N, Robertson, Nr, Rocheleau, G, Roden, M, Sampson, Mj, Saxena, R, Shields, Bm, Shrader, P, Sigurdsson, G, Sparsø, T, Strassburger, K, Stringham, Hm, Sun, Q, Thorand, B, Tichet, J, van Dam RM, van Haeften TW, van Herpt, T, van Vliet JV, Bragi Walters, G, Wijmenga, C, Witteman, J, Bergman, Rn, Cauchi, S, Gyllensten, U, Hansen, T, Hide, Wa, Hitman, Ga, Hofman, A, Hunter, Dj, Hveem, K, Mohlke, Kl, Morris, Ad, Palmer, Cn, Pramstaller, Pp, Rudan, I, Sijbrands, E, Stein, Ld, Tuomilehto, J, Uitterlinden, A, Abecasis, Gr, Boehm, Bo, Campbell, H, Daly, Mj, Hattersley, At, Hu, Fb, Pankow, Js, Pedersen, O, Wichmann, E, Florez, Jc, Sladek, R, Thorsteinsdottir, U, Wilson, Jf, Illig, T, Stefansson, K, Altshuler, D, Speliotes, Ek, Berndt, Si, Monda, Kl, Allen, Hl, Mägi, R, Randall, Jc, Vedantam, S, Winkler, Tw, Workalemahu, T, Heid, Im, Wood, Ar, Weyant, Rj, Estrada, K, Liang, L, Nemesh, J, Park, Jh, Kilpeläinen, To, Yang, J, Esko, T, Feitosa, Mf, Kutalik, Z, Mangino, M, Scherag, A, Smith, Av, Welch, R, Zhao, Jh, Aben, Kk, Absher, Dm, Dixon, Al, Fisher, E, Glazer, Nl, Goddard, Me, Heard Costa NL, Hoesel, V, Hottenga, Jj, Johansson, Å, Johnson, T, Ketkar, S, Lamina, C, Li, S, Moffatt, Mf, Myers, Rh, Peters, Mj, Preuss, M, Ripatti, S, Rivadeneira, F, Sandholt, C, Timpson, Nj, Tyrer, Jp, van Wingerden, S, White, Cc, Wiklund, F, Barlassina, C, Chasman, Di, Cooper, Mn, Jansson, Jo, Lawrence, Rw, Pellikka, N, Shi, J, Thiering, E, Alavere, H, Alibrandi, Mt, Arnold, Am, Aspelund, T, Atwood, Ld, Balmforth, Aj, Ben Shlomo, Y, Bergmann, S, Biebermann, H, Blakemore, Ai, Boes, T, Bornstein, Sr, Brown, Mj, Buchanan, Ta, Busonero, F, Cappuccio, Fp, Cavalcanti Proença, C, Ida Chen YD, Chen, Cm, Coin, L, Connell, J, Day, In, den Heijer, M, Duan, J, Ebrahim, S, Elliott, P, Elosua, R, Eiriksdottir, G, Facheris, Mf, Felix, Sb, Fischer Posovszky, P, Folsom, Ar, Friedrich, N, Freimer, Nb, Fu, M, Gaget, S, Gejman, Pv, Geus, Ej, Gjesing, Ap, Goyette, P, Grässler, J, Greenawalt, Dm, Gudnason, V, Hartikainen, Al, Hall, As, Havulinna, As, Hayward, C, Heath, Ac, Hengstenberg, C, Hicks, Aa, Hinney, A, Homuth, G, Hui, J, Igl, W, Iribarren, C, Jacobs, Kb, Jarick, I, Jewell, E, John, U, Jousilahti, P, Jula, A, Kaakinen, M, Kaplan, Lm, Kathiresan, S, Kettunen, J, Kinnunen, L, Knowles, Jw, Kolcic, I, König, Ir, Koskinen, S, Kovacs, P, Kvaløy, K, Laitinen, J, Lantieri, O, Lanzani, C, Launer, Lj, Lecoeur, C, Terho, L, Lettre, G, Liu, J, Lokki, Ml, Lorentzon, M, Luben, Rn, Ludwig, B, Magic, Manunta, P, Marek, D, Martin, Ng, Mcardle, Wl, Mccarthy, A, Mcknight, B, Melander, O, Meyre, D, Montgomery, Gw, Mulic, R, Ngwa, Js, Nelis, M, Neville, Mj, Nyholt, Dr, O'Donnell, Cj, O'Rahilly, S, Ong, Kk, Oostra, B, Paré, G, Parker, An, Perola, M, Pichler, I, Pietiläinen, Kh, Platou, Cg, Polasek, O, Pouta, A, Rafelt, S, Raitakari, O, Rayner, Nw, Ridderstråle, M, Rief, W, Ruokonen, A, Rzehak, P, Salomaa, V, Sanders, Ar, Sandhu, Ms, Sanna, S, Saramies, J, Savolainen, Mj, Scherag, S, Schipf, S, Schreiber, S, Schunkert, H, Silander, K, Sinisalo, J, Siscovick, Ds, Smit, Jh, Soranzo, N, Sovio, U, Stephens, J, Surakka, I, Tammesoo, Ml, Tardif, Jc, Teder Laving, M, Teslovich, Tm, Thompson, Jr, Thomson, B, Tönjes, A, van Meurs JB, van Ommen GJ, Vatin, V, Viikari, J, Visvikis Siest, S, Vitart, V, Vogel, Ci, Waite, Ll, Wallaschofski, H, Walters, Gb, Widen, E, Wiegand, S, Wild, Sh, Willemsen, G, Witte, Dr, Witteman, Jc, Xu, J, Zhang, Q, Zgaga, L, Ziegler, A, Zitting, P, Beilby, Jp, Farooqi, Is, Hebebrand, J, Huikuri, Hv, James, Al, Kähönen, M, Levinson, Df, Macciardi, F, Nieminen, Ms, Ohlsson, C, Palmer, Lj, Ridker, Pm, Stumvoll, M, Beckmann, Js, Boeing, H, Dorret, I. 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S.
Publikováno v:
Morris, A & Rudan, I & Campbell, H & Wilson, J 2011, ' Genome-wide association identifies nine common variants associated with fasting proinsulin levels and provides new insights into the pathophysiology of type 2 diabetes ', Diabetes, vol. 60, no. 10, pp. 2624-34 . https://doi.org/10.2337/db11-0415
Diabetes; Vol 60
Diabetes, Vol. 60, No 10 (2011) pp. 2624-34
Diabetes, 60(10), 2624-2634. American Diabetes Association Inc.
Diabetes, 60, 2624-34
Diabetes, 60(10), 2624-2634. AMER DIABETES ASSOC
Diabetes
Diabetes, 60, 10, pp. 2624-34
Diabetes, 60(10), 2624-2634
Strawbridge, R J, Dupuis, J, Prokopenko, I, Barker, A, Ahlqvist, E, Rybin, D, Petrie, J R, Travers, M E, Bouatia-Naji, N, Dimas, A S, Nica, A, Wheeler, E, Chen, H, Voight, B F, Taneera, J, Kanoni, S, Peden, J F, Turrini, F, Gustafsson, S, Zabena, C, Almgren, P, Barker, D J P, Barnes, D, Dennison, E M, Eriksson, J G, Eriksson, P, Eury, E, Folkersen, L, Fox, C S, Frayling, T M, Goel, A, Gu, H F, Horikoshi, M, Isomaa, B, Jackson, A U, Jameson, K A, Kajantie, E, Kerr-Conte, J, Kuulasmaa, T, Kuusisto, J, Loos, R J F, Luan, J, Makrilakis, K, Manning, A K, Martínez-Larrad, M T, Narisu, N, Mannila, M N, the DIAGRAM Consortium (Torsten Lauritzen, Niels Grarup; members), the GIANT Consortium (Daniel R. Witte; member), the MuTHER Consortium, the CARDIoGRAM Consortium & the C4D Consortium 2011, ' Genome-wide association identifies nine common variants associated with fasting proinsulin levels and provides new insights into the pathophysiology of type 2 diabetes ', Diabetes, vol. 60, no. 10, pp. 2624-2634 . https://doi.org/10.2337/db11-0415
Strawbridge, R J, Dupuis, J, Prokopenko, I, Barker, A, Ahlqvist, E, Rybin, D, Petrie, J R, Bouatia-Naji, N, Dimas, A S, Nica, A, Wheeler, E, Chen, H, Voight, B F, Taneera, J, Kanoni, S, Hottenga, J J, de Geus, E J C, Willemsen, G, Boomsma, D I, Forsen, T J, Clarke, R, Franzosi, M G, Seedorf, U, Watkins, H, Froguel, P, Johnson, P, Deloukas, P, Collins, F S, Laakso, M, Dermitzakis, E T, Boehnke, M, McCarthy, M I, Wareham, N J, Groop, L, Pattou, F, Gloyn, A L, Dedoussis, G V, Lyssenko, V, Meigs, J B, Barroso, I, Watanabe, R M, Ingelsson, E, Langenberg, C, Hamsten, A & Florez, J C 2011, ' Genome-wide association identifies nine common variants associated with fasting proinsulin levels and provides new insights into the pathophysiology of type 2 diabetes ', Diabetes, vol. 60, no. 10, pp. 2624-2634 . https://doi.org/10.2337/db11-0415
Diabetes; Vol 60
Diabetes, Vol. 60, No 10 (2011) pp. 2624-34
Diabetes, 60(10), 2624-2634. American Diabetes Association Inc.
Diabetes, 60, 2624-34
Diabetes, 60(10), 2624-2634. AMER DIABETES ASSOC
Diabetes
Diabetes, 60, 10, pp. 2624-34
Diabetes, 60(10), 2624-2634
Strawbridge, R J, Dupuis, J, Prokopenko, I, Barker, A, Ahlqvist, E, Rybin, D, Petrie, J R, Travers, M E, Bouatia-Naji, N, Dimas, A S, Nica, A, Wheeler, E, Chen, H, Voight, B F, Taneera, J, Kanoni, S, Peden, J F, Turrini, F, Gustafsson, S, Zabena, C, Almgren, P, Barker, D J P, Barnes, D, Dennison, E M, Eriksson, J G, Eriksson, P, Eury, E, Folkersen, L, Fox, C S, Frayling, T M, Goel, A, Gu, H F, Horikoshi, M, Isomaa, B, Jackson, A U, Jameson, K A, Kajantie, E, Kerr-Conte, J, Kuulasmaa, T, Kuusisto, J, Loos, R J F, Luan, J, Makrilakis, K, Manning, A K, Martínez-Larrad, M T, Narisu, N, Mannila, M N, the DIAGRAM Consortium (Torsten Lauritzen, Niels Grarup; members), the GIANT Consortium (Daniel R. Witte; member), the MuTHER Consortium, the CARDIoGRAM Consortium & the C4D Consortium 2011, ' Genome-wide association identifies nine common variants associated with fasting proinsulin levels and provides new insights into the pathophysiology of type 2 diabetes ', Diabetes, vol. 60, no. 10, pp. 2624-2634 . https://doi.org/10.2337/db11-0415
Strawbridge, R J, Dupuis, J, Prokopenko, I, Barker, A, Ahlqvist, E, Rybin, D, Petrie, J R, Bouatia-Naji, N, Dimas, A S, Nica, A, Wheeler, E, Chen, H, Voight, B F, Taneera, J, Kanoni, S, Hottenga, J J, de Geus, E J C, Willemsen, G, Boomsma, D I, Forsen, T J, Clarke, R, Franzosi, M G, Seedorf, U, Watkins, H, Froguel, P, Johnson, P, Deloukas, P, Collins, F S, Laakso, M, Dermitzakis, E T, Boehnke, M, McCarthy, M I, Wareham, N J, Groop, L, Pattou, F, Gloyn, A L, Dedoussis, G V, Lyssenko, V, Meigs, J B, Barroso, I, Watanabe, R M, Ingelsson, E, Langenberg, C, Hamsten, A & Florez, J C 2011, ' Genome-wide association identifies nine common variants associated with fasting proinsulin levels and provides new insights into the pathophysiology of type 2 diabetes ', Diabetes, vol. 60, no. 10, pp. 2624-2634 . https://doi.org/10.2337/db11-0415
OBJECTIVE Proinsulin is a precursor of mature insulin and C-peptide. Higher circulating proinsulin levels are associated with impaired β-cell function, raised glucose levels, insulin resistance, and type 2 diabetes (T2D). Studies of the insulin proc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ca4fdf7c5b7d3a200245a047f2fc720
https://hdl.handle.net/20.500.11820/d6fd0145-660e-41a0-96e6-84d3af65fb9b
https://hdl.handle.net/20.500.11820/d6fd0145-660e-41a0-96e6-84d3af65fb9b
Autor:
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Publikováno v:
Nature, 518(7538), 197-206. Nature Publishing Group
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Nature, 518(7538), 197. Nature Publishing Group
Nature
Nature, 518(7538), 197-U401
Nature, Vol. 518, No 7538 (2015) pp. 197-206
Nature, vol. 518, no. 7538, pp. 197-206
Nature 518(7538), 197-206 (2015). doi:10.1038/nature14177
Repositorio Institucional de la Consejería de Sanidad de la Comunidad de Madrid
Consejería de Sanidad de la Comunidad de Madrid
Locke, A E, Kahali, B, Berndt, S I, Justice, A E, Pers, T H, Day, F R, Powell, C, Vedantam, S, Buchkovich, M L, Yang, J, Croteau-Chonka, D C, Esko, T, Fall, T, Ferreira, T, Gustafsson, S, Kutalik, Z, Luan, J, Maegi, R, Randall, J C, Winkler, T W, Wood, A R, Workalemahu, T, Faul, J D, Smith, J A, Zhao, J H, Zhao, W, Chen, J, Fehrmann, R, Hedman, A K, Karjalainen, J, Schmidt, E M, Absher, D, Amin, N, Anderson, D, Beekman, M & Bolton, J L & Bragg-Gresham, L & Buyske, S & Demirkan, A & Deng, G & Fraser, R M & Hayward, C & McLachlan, S & Campbell, H & Morris, A D & Price, J F & Rudan, I & Walker, M & Wilson, J F & Visscher, P M 2015, ' Genetic studies of body mass index yield new insights for obesity biology ', Nature, vol. 518, no. 7538, pp. 197-U401 . https://doi.org/10.1038/nature14177
Nature, 518(7538), 197-U401. Nature Publishing Group
Nature, 518, 7538, pp. 197-206
Nature, 518, 197-206
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Abecasis, G R, Franke, L, Frayling, T M, McCarthy, M I, Visscher, P M, Scherag, A, Willer, C J, Boehnke, M, Mohlke, K L, Lindgren, C M, Beckmann, J S, Barroso, I, North, K E, Ingelsson, E, Hirschhorn, J N, Loos, R J F & Speliotes, E K 2015, ' Genetic studies of body mass index yield new insights for obesity biology ', Nature, vol. 518, no. 7538, pp. 197-206 . https://doi.org/10.1038/nature14177
Nature, 518(7538), 197. Nature Publishing Group
Nature
Nature, 518(7538), 197-U401
Nature, Vol. 518, No 7538 (2015) pp. 197-206
Nature, vol. 518, no. 7538, pp. 197-206
Nature
Repositorio Institucional de la Consejería de Sanidad de la Comunidad de Madrid
Consejería de Sanidad de la Comunidad de Madrid
Locke, A E, Kahali, B, Berndt, S I, Justice, A E, Pers, T H, Day, F R, Powell, C, Vedantam, S, Buchkovich, M L, Yang, J, Croteau-Chonka, D C, Esko, T, Fall, T, Ferreira, T, Gustafsson, S, Kutalik, Z, Luan, J, Maegi, R, Randall, J C, Winkler, T W, Wood, A R, Workalemahu, T, Faul, J D, Smith, J A, Zhao, J H, Zhao, W, Chen, J, Fehrmann, R, Hedman, A K, Karjalainen, J, Schmidt, E M, Absher, D, Amin, N, Anderson, D, Beekman, M & Bolton, J L & Bragg-Gresham, L & Buyske, S & Demirkan, A & Deng, G & Fraser, R M & Hayward, C & McLachlan, S & Campbell, H & Morris, A D & Price, J F & Rudan, I & Walker, M & Wilson, J F & Visscher, P M 2015, ' Genetic studies of body mass index yield new insights for obesity biology ', Nature, vol. 518, no. 7538, pp. 197-U401 . https://doi.org/10.1038/nature14177
Nature, 518(7538), 197-U401. Nature Publishing Group
Nature, 518, 7538, pp. 197-206
Nature, 518, 197-206
Item does not contain fulltext Obesity is heritable and predisposes to many diseases. To understand the genetic basis of obesity better, here we conduct a genome-wide association study and Metabochip meta-analysis of body mass index (BMI), a measure
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e9c5084ccf8e95018f370ac56cecd0a
https://research.vu.nl/en/publications/58992b26-1689-48dd-bb82-82548598fe61
https://research.vu.nl/en/publications/58992b26-1689-48dd-bb82-82548598fe61
Autor:
Shungin, Dmitry, Winkler, Thomas W, Workalemahu, Tsegaselassie, Hartman, Catharina A, Duncan, Emma L, Ntzani, Evangelia E, Oei, Ling, Albagha, Omar M E, Amin, Najaf, Kemp, John P, Koller, Daniel L, Li, Guo, Liu, Ching-Ti, Minster, Ryan L, Hassinen, Maija, Moayyeri, Alireza, Vandenput, Liesbeth, Willner, Dana, Xiao, Su-Mei, Yerges-Armstrong, Laura M, Zheng, Hou-Feng, Alonso, Nerea, Eriksson, Joel, Kammerer, Candace M, Kaptoge, Stephen K, Hayward, Caroline, Leo, Paul J, Thorleifsson, Gudmar, Wilson, Scott G, Wilson, James F, Aalto, Ville, Alen, Markku, Aragaki, Aaron K, Aspelund, Thor, Center, Jacqueline R, Dailiana, Zoe, Heikkilä, Kauko, Duggan, David J, Garcia, Melissa, Garcia-Giralt, Natàlia, Giroux, Sylvie, Hallmans, Göran, Hocking, Lynne J, Husted, Lise Bjerre, Jameson, Karen A, Khusainova, Rita, Kim, Ghi Su, Herzig, Karl-Heinz, Kooperberg, Charles, Koromila, Theodora, Kruk, Marcin, Laaksonen, Marika, Lacroix, Andrea Z, Lee, Seung Hun, Leung, Ping C, Lewis, Joshua R, Masi, Laura, Mencej-Bedrac, Simona, Helmer, Quinta, Nguyen, Tuan V, Nogues, Xavier, Patel, Millan S, Prezelj, Janez, Rose, Lynda M, Scollen, Serena, Siggeirsdottir, Kristin, Smith, Albert V, Svensson, Olle, Trompet, Stella, Hillege, Hans L, Trummer, Olivia, van Schoor, Natasja M, Woo, Jean, Zhu, Kun, Balcells, Susana, Brandi, Maria Luisa, Buckley, Brendan M, Cheng, Sulin, Christiansen, Claus, Cooper, Cyrus, Holmen, Oddgeir, Dedoussis, George, Ford, Ian, Frost, Morten, Goltzman, David, González-Macías, Jesús, Kähönen, Mika, Karlsson, Magnus, Khusnutdinova, Elza, Koh, Jung-Min, Kollia, Panagoula, Hunt, Steven C, Langdahl, Bente Lomholt, Leslie, William D, Lips, Paul, Ljunggren, Östen, Lorenc, Roman S, Marc, Janja, Mellström, Dan, Obermayer-Pietsch, Barbara, Olmos, José M, Pettersson-Kymmer, Ulrika, Isaacs, Aaron, Reid, David M, Riancho, José A, Ridker, Paul M, Rousseau, François, Slagboom, P Eline, Tang, Nelson L S, Urreizti, Roser, Van Hul, Wim, Viikari, Jorma, Zarrabeitia, María T, Wu, Joseph M W, 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Publikováno v:
Nature, vol. 518, no. 7538, pp. 187-196
Nature
Nature, 2015, 518 (7538), pp.187-96. ⟨10.1038/nature14132⟩
Nature 518(7538), 187-196 (2015). doi:10.1038/nature14132
Nature, 518(7538), 187-U378. Nature Publishing Group
Nature, Nature Publishing Group, 2015, 518 (7538), pp.187-96. ⟨10.1038/nature14132⟩
Nature, 518(7538), 187-196. Nature Publishing Group
Nature, 518(7538), 187. Nature Publishing Group
Nature, 518(7538), 187-U378
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Sennblad, B, Seufferlein, T, Sitlani, C M, Smith, A V, Stirrups, K, Stringham, H M, Sundstrom, J, Swertz, M A, Swift, A J, Syvanen, A, Tayo, B O, Thorand, B, Thorleifsson, G, Tomaschitz, A, Troffa, C, van Oort, F V A, Verweij, N, Vonk, J M, Waite, L L, Wennauer, R, Wilsgaard, T, Wojczynski, M K, Wong, A, Zhang, Q, Zhao, J H, Brennan, E P, Choi, M, Eriksson, P, Folkersen, L, Franco-Cereceda, A, Gharavi, A G, Hedman, A K, Hivert, M, Huang, J, Kanoni, S, Karpe, F, Keildson, S, Kiryluk, K, Liang, L, Lifton, R P, Ma, B, McKnight, A J, McPherson, R, Metspalu, A, Min, J L, Moffatt, M F, Montgomery, G W, Murabito, J M, Nicholson, G, Nyholt, DR, Olsson, C, Perry, J R B, Reinmaa, E, Salem, R M, Sandholm, N, Schadt, E E, Scott, R A, Stolk, L, Vallejo, E E, Westra, H, Zondervan, K T, Amouyel, P, Arveiler, D, Bakker, S J L, Beilby, J, Bergman, R N, Blangero, J, Brown, M J, Burnier, M, Campbell, H, Chakravarti, A, Chiness, P S, Claudi-Boehmi, S, Collins, F S, Crawford, D C, Danesh, J, de Faire, U, de Geus, E J C, Doerr, M, Erbel, R, Eriksson, J G, Farrall, M, Ferrannini, E, Ferrieres, J, Forouhi, N G, Forrester, T, Franco, O H, Gansevoort, R T, Gieger, C, Gudnason, V, Haiman, C A, Harris, T B, Hattersley, A T, Heliovaara, M, Hicks, A A, Hingorani, A D, Hoffmann, W, Hofman, A, Homuth, G, Humphries, S E, Hyppoenen, E, Illig, T, Jarvelin, M, Johansen, B, Jousilahti, P, Jula, A M, Kaprio, J, Kee, F, Keinanen-Kiukaanniemi, S M, Kooner, J S, Kooperberg, C, Kovacs, P, Kraja, A T, Kumari, M, Kuulasmaa, K, Kuusisto, J, Lakka, T A, Langenberg, C, Le Marchand, L, Lehtimaki, T, Lyssenko, V, Mannisto, S, Marette, A, Matise, T C, McKenzie, C A, McKnight, B, Musk, A W, Mohlenkamp, S, Morris, A D, Nelis, M, Ohlsson, C, Oldehinkel, A J, Ong, K K, Palmer, L J, Penninx, B W J H, Peters, A, Pramstaller, P P, Raitakari, O T, Rankinen, T, Rao, D C, Rice, T K, Ridker, P M, Ritchie, M D, Rudan, I, Salomaa, V, Samani, N J, Saramies, J, Sarzynski, M A, Schwarz, P E H, Shuldiner, A R, Staessen, J A, Steinthorsdottir, V, Stolk, R P, Strauch, K, Toenjes, A, Tremblay, A, Tremoli, E, Vohl, M, Voelker, U, Vollenweider, P, Wilson, J F, Witteman, J C, Adair, L S, Bochud, M, Boehm, B O, Bornstein, S R, Bouchard, C, Cauchi, S, Caulfield, M J, Chambers, J C, Chasman, D I, Cooper, R S, Dedoussis, G, Ferrucci, L, Froguel, P, Grabe, H, Hamsten, A, Hui, J, Hveem, K, Joeckel, K, Kivimaki, M, Kuh, D, Laakso, M, Liu, Y, Maerz, W, Munroe, P B, Njolstad, I, Oostra, B A, Palmer, C N A, Pedersen, N L, Perola, M, Perusse, L, Peters, U, Power, C, Quertermous, T, Rauramaa, R, Rivadeneira, F, Saaristo, T E, Saleheen, D, Sinisalo, J, Slagboom, P E, Snieder, H, Spector, T D, Thorsteinsdottir, U R, Stumvoll, M, Tuomilehto, J, Uitterlinden, A G, Uusitupa, M, van der Harst, P, Veronesi, G, Walker, M, Wareham, N J, Watkins, H, Wichmann, H, Abecasis, G R, Assimes, T L, Berndt, S I, Boehnkes, M, Borecki, I B, Deloukas, P, Franke, L, Frayling, T M, Groop, L C, Hunter, D J, Kaplan, R C, O'Connell, J R, Qi, L, Schlessinger, D, Strachan, D P, Stefansson, K, van Dujin, C M, Willer, C J, Visscher, P M, Yang, J, Hirschhorn, J N, Zillikens, M C, McCarthy, M I, Speliotes, E K, North, K E, Fox, C S, Barroso, I, Franks, P W, Ingelsson, E, Heid, I M, Loos, R J F, Cupples, L A, Morris, A P, Lindgren, C M & Mohlke, K L 2015, ' New genetic loci link adipose and insulin biology to body fat distribution ', Nature, vol. 518, no. 7538, pp. 187-196 . https://doi.org/10.1038/nature14132
Nature, Nature Publishing Group, 2015, 518 (7538), pp.187-96. 〈10.1038/nature14132〉
Repositorio Institucional de la Consejería de Sanidad de la Comunidad de Madrid
Consejería de Sanidad de la Comunidad de Madrid
Nature
Nature, 2015, 518 (7538), pp.187-96. ⟨10.1038/nature14132⟩
Nature
Nature, 518(7538), 187-U378. Nature Publishing Group
Nature, Nature Publishing Group, 2015, 518 (7538), pp.187-96. ⟨10.1038/nature14132⟩
Nature, 518(7538), 187-196. Nature Publishing Group
Nature, 518(7538), 187. Nature Publishing Group
Nature, 518(7538), 187-U378
Shungin, D, Winkler, T W, Croteau-Chonka, D C, Ferreira, T, Lockes, A E, Maegi, R, Strawbridge, R J, Pers, T H, Fischer, K, Justice, A E, Workalemahu, T, Wu, J M W, Buchkovich, M L, Heard-Costa, N L, Roman, T S, Drong, A W, Song, C, Gustafsson, S, Day, F R, Esko, T, Fall, T, Kutalik, Z, Luan, J, Randall, J C, Scherag, A, Vedantam, S, Wood, A R, Chen, J, Fehrmann, R, Karjalainen, J, Kahali, B, Liu, C, Schmidt, E M, Absher, D, Amin, N, Anderson, D, Beekman, M, Bragg-Gresham, J L, Buyske, S, Demirkan, A, Ehret, G B, Feitosa, M F, Goel, A, Jackson, A U, Johnson, T, Kleber, M E, Kristiansson, K, Mangino, M, Leach, I M, Medina-Gomez, C, Palmer, C D, Pasko, D, Pechlivaniss, S, Peters, MJ, Prokopenko, I, Stancakova, A, Sung, Y J, Tanakam, T, Teumer, A, van Vliet-Ostaptchouk, J V, Yengo, L, Zhang, W, Albrecht, E, Arnlov, J, Arscott, G M, Bandinelli, S, Barrett, A, Bellis, C, Bennett, A J, Berne, C, Blueher, M, Buhringer, S, Bonnet, F, Boettcher, Y, Bruinenberg, M, Carba, D B, Caspersen, I H, Clarke, R, Daw, E W, Deelen, J, Deelman, E, Delgado, G, Doney, A S F, Eklund, N, Erdos, M R, Estrada, K, Eury, E, Friedrichs, N, Garcia, M E, Giedraitis, V, Gigante, B, Go, A S, Golay, A, Grallert, H, Grammer, T B, Graessler, J, Grewal, J, Groves, C J, Haller, T, Hallmans, G, Hartman, C A, Hassinen, M, Hayward, C, Heikkila, K, Herzig, K, Helmer, Q, Hillege, H L, Holmen, O, Hunt, S C, Isaacs, A, Ittermann, T, James, A L, Johansson, I, Juliusdottir, T, Kalafati, I, Kinnunen, L, Koenig, W, Kooner, I K, Kratzer, W, Lamina, C, Leander, K, Lee, N R, Lichtner, P, Lind, L, Lindstrom, J, Lobbens, S, Lorentzon, M, Mach, F, Magnusson, P K E, Mahajan, A, McArdle, W L, Menni, C, Merger, S, Mihailov, E, Milani, L, Mills, R, Moayyeri, A, Monda, K L, Mooijaart, S P, Muehleisen, T W, Mulas, A, Mueller, G, Mueller-Nurasyid, M, Nagaraja, R, Nalls, M A, Narisu, N, Glorioso, N, Nolte, I M, Olden, M, Rayner, N W, Renstrom, F, Ried, J S, Robertson, N R, Rose, L M, Sanna, S, Scharnagl, H, Scholtens, S, Sennblad, B, Seufferlein, T, Sitlani, C M, Smith, A V, Stirrups, K, Stringham, H M, Sundstrom, J, Swertz, M A, Swift, A J, Syvanen, A, Tayo, B O, Thorand, B, Thorleifsson, G, Tomaschitz, A, Troffa, C, van Oort, F V A, Verweij, N, Vonk, J M, Waite, L L, Wennauer, R, Wilsgaard, T, Wojczynski, M K, Wong, A, Zhang, Q, Zhao, J H, Brennan, E P, Choi, M, Eriksson, P, Folkersen, L, Franco-Cereceda, A, Gharavi, A G, Hedman, A K, Hivert, M, Huang, J, Kanoni, S, Karpe, F, Keildson, S, Kiryluk, K, Liang, L, Lifton, R P, Ma, B, McKnight, A J, McPherson, R, Metspalu, A, Min, J L, Moffatt, M F, Montgomery, G W, Murabito, J M, Nicholson, G, Nyholt, DR, Olsson, C, Perry, J R B, Reinmaa, E, Salem, R M, Sandholm, N, Schadt, E E, Scott, R A, Stolk, L, Vallejo, E E, Westra, H, Zondervan, K T, Amouyel, P, Arveiler, D, Bakker, S J L, Beilby, J, Bergman, R N, Blangero, J, Brown, M J, Burnier, M, Campbell, H, Chakravarti, A, Chiness, P S, Claudi-Boehmi, S, Collins, F S, Crawford, D C, Danesh, J, de Faire, U, de Geus, E J C, Doerr, M, Erbel, R, Eriksson, J G, Farrall, M, Ferrannini, E, Ferrieres, J, Forouhi, N G, Forrester, T, Franco, O H, Gansevoort, R T, Gieger, C, Gudnason, V, Haiman, C A, Harris, T B, Hattersley, A T, Heliovaara, M, Hicks, A A, Hingorani, A D, Hoffmann, W, Hofman, A, Homuth, G, Humphries, S E, Hyppoenen, E, Illig, T, Jarvelin, M, Johansen, B, Jousilahti, P, Jula, A M, Kaprio, J, Kee, F, Keinanen-Kiukaanniemi, S M, Kooner, J S, Kooperberg, C, Kovacs, P, Kraja, A T, Kumari, M, Kuulasmaa, K, Kuusisto, J, Lakka, T A, Langenberg, C, Le Marchand, L, Lehtimaki, T, Lyssenko, V, Mannisto, S, Marette, A, Matise, T C, McKenzie, C A, McKnight, B, Musk, A W, Mohlenkamp, S, Morris, A D, Nelis, M, Ohlsson, C, Oldehinkel, A J, Ong, K K, Palmer, L J, Penninx, B W J H, Peters, A, Pramstaller, P P, Raitakari, O T, Rankinen, T, Rao, D C, Rice, T K, Ridker, P M, Ritchie, M D, Rudan, I, Salomaa, V, Samani, N J, Saramies, J, Sarzynski, M A, Schwarz, P E H, Shuldiner, A R, Staessen, J A, Steinthorsdottir, V, Stolk, R P, Strauch, K, Toenjes, A, Tremblay, A, Tremoli, E, Vohl, M, Voelker, U, Vollenweider, P, Wilson, J F, Witteman, J C, Adair, L S, Bochud, M, Boehm, B O, Bornstein, S R, Bouchard, C, Cauchi, S, Caulfield, M J, Chambers, J C, Chasman, D I, Cooper, R S, Dedoussis, G, Ferrucci, L, Froguel, P, Grabe, H, Hamsten, A, Hui, J, Hveem, K, Joeckel, K, Kivimaki, M, Kuh, D, Laakso, M, Liu, Y, Maerz, W, Munroe, P B, Njolstad, I, Oostra, B A, Palmer, C N A, Pedersen, N L, Perola, M, Perusse, L, Peters, U, Power, C, Quertermous, T, Rauramaa, R, Rivadeneira, F, Saaristo, T E, Saleheen, D, Sinisalo, J, Slagboom, P E, Snieder, H, Spector, T D, Thorsteinsdottir, U R, Stumvoll, M, Tuomilehto, J, Uitterlinden, A G, Uusitupa, M, van der Harst, P, Veronesi, G, Walker, M, Wareham, N J, Watkins, H, Wichmann, H, Abecasis, G R, Assimes, T L, Berndt, S I, Boehnkes, M, Borecki, I B, Deloukas, P, Franke, L, Frayling, T M, Groop, L C, Hunter, D J, Kaplan, R C, O'Connell, J R, Qi, L, Schlessinger, D, Strachan, D P, Stefansson, K, van Dujin, C M, Willer, C J, Visscher, P M, Yang, J, Hirschhorn, J N, Zillikens, M C, McCarthy, M I, Speliotes, E K, North, K E, Fox, C S, Barroso, I, Franks, P W, Ingelsson, E, Heid, I M, Loos, R J F, Cupples, L A, Morris, A P, Lindgren, C M & Mohlke, K L 2015, ' New genetic loci link adipose and insulin biology to body fat distribution ', Nature, vol. 518, no. 7538, pp. 187-196 . https://doi.org/10.1038/nature14132
Nature, Nature Publishing Group, 2015, 518 (7538), pp.187-96. 〈10.1038/nature14132〉
Repositorio Institucional de la Consejería de Sanidad de la Comunidad de Madrid
Consejería de Sanidad de la Comunidad de Madrid
Body fat distribution is a heritable trait and a well-established predictor of adverse metabolic outcomes, independent of overall adiposity. To increase our understanding of the genetic basis of body fat distribution and its molecular links to cardio
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https://serval.unil.ch/notice/serval:BIB_10C25BFE14DB
https://serval.unil.ch/notice/serval:BIB_10C25BFE14DB