Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Hisashi Oishi"'
Autor:
Adel Abdel-Moneim, Ahmed A G El-Shahawy, Sanaa M. Abd El-Twab, Hossam H. Shawki, Ahmed I. Yousef, Hisashi Oishi
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 133, Iss, Pp 111027-(2021)
Several reports have been shown the pivotal role of oxidative stress in the progression of diabetes mellitus and its complications. Polydatin (PD), a natural phytochemical, has wide range of pharmacological actions, however, the underlying beneficial
Autor:
Satoru Takahashi, Shayida Maimaiti, Kiyohito Ogata, Takashi Kudo, Hisashi Oishi, Hossam H. Shawki, Gulibaikelamu Xiafukaiti, Akihiro Kuno
Publikováno v:
Molecular and Cellular Biology
The pancreatic-islet-enriched transcription factors MafA and MafB have unique expression patterns in β cells in rodents. MafA is specifically expressed in β cells and is a key regulatory factor for maintaining adult β-cell function, whereas MafB p
Autor:
Satoru Takahashi, Chioma M. Ugboma, Yunshin Jung, Hisashi Oishi, Walaa A Basha, Miki Shimbo, Akihiro Kuno, Takashi Kudo, Megumi C. Katoh
Publikováno v:
Molecular and cellular biology. 38(8)
The MafB transcription factor is expressed in pancreatic α and β cells during development but becomes exclusive to α cells in adult rodents. Mafb-null (Mafb-/- ) mice were reported to have reduced α- and β-cell numbers throughout embryonic devel
Autor:
Megumi C. Katoh, Ahmed A. H. Abdellatif, Satoru Takahashi, Salah E. El-Morsy, Gulibaikelamu Xiafukaiti, Hisashi Oishi, Takashi Kudo, Yu-Hsin Chang, Kiyohito Ogata
Publikováno v:
Experimental Animals
The members of the MAF family of transcription factors are homologs of v-Maf -the oncogenic component of the avian retrovirus AS42. The MAF family is subdivided into 2 groups, small and large MAFs. To elucidate the role of the large MAF transcription
Autor:
Satoru Takahashi, Wataru Nishimura, Kazuki Yasuda, Hisashi Oishi, Nobuaki Funahashi, Toshiyoshi Fujiwara
Publikováno v:
Endocrine Journal. 62:37-51
MafA and MafB are basic leucine zipper transcription factors expressed in mature pancreatic β- and α-cells, respectively. MafA is not only an insulin gene transcription factor but is also critical for the maturation and maintenance of β-cell funct
Autor:
Satoru Takahashi, Margarete M. S. Heck, Jeffrey K Usui, Hisashi Oishi, Yunshin Jung, Ruyi Zhou, Toshiki Kato, Masafumi Muratani
Publikováno v:
Endocrinology. 159(2)
Adenoviral gene transfer of key β cell developmental regulators including Pdx1, Neurod1, and Mafa (PDA) has been reported to generate insulin-producing cells in the liver. However, PDA insulin secretion is transient and glucose unresponsive. Here, w
Autor:
Xiafukaiti, Gulibaikelamu, Maimaiti, Shayida, Kiyohito Ogata, Akihiro Kuno, Takashi Kudo, Shawki, Hossam H., Hisashi Oishi, Satoru Takahashi
Publikováno v:
Molecular & Cellular Biology; Sep2019, Vol. 39 Issue 17, p1-22, 22p
Autor:
Takashi Moriguchi, Miwako Kajihara, Michito Hamada, Satoru Takahashi, Masayuki Yamamoto, Ritsuko Esaki, Hisashi Oishi, Kazuteru Hasegawa, Chuan Zhang, Homare Shimohata, James Douglas Engel, Ayako Harada, Naoki Morito, Takashi Kudo
Publikováno v:
Molecular and Cellular Biology. 25:4969-4976
MafA is a transcription factor that binds to the promoter in the insulin gene and has been postulated to regulate insulin transcription in response to serum glucose levels, but there is no current in vivo evidence to support this hypothesis. To analy
Autor:
Masashi Yanagisawa, Yoshiharu Miyamoto, Joji Yamamoto, Mitsuyo Okazaki, Katsumi Imaizumi, Shinichi Usui, Minoru Okubo, Takahiro Fujino, Hisashi Oishi, Yukio Ikeda, Masao Ono, Kenta Magoori, Hiroko Tomoyori, Hideyuki Sone, Sadao Takahashi, Shinji Takada, Masato Nose, Akihisa Kamataki, Hiroshi Asaba, Ryoichi X. Ioka, Juro Sakai, Toshio Murase, Dong Ho Kim, Tokuo T. Yamamoto, Man Jong Kang
Publikováno v:
Proceedings of the National Academy of Sciences. 100:229-234
A Wnt coreceptor low-density lipoprotein receptor-related protein 5 (LRP5) plays an essential role in bone accrual and eye development. Here, we show that LRP5 is also required for normal cholesterol and glucose metabolism. The production of mice lac
Autor:
Satoru Takahashi, Yoko Tanimoto, Atsushi Yoshiki, Yoko Daitoku, Fumihiro Sugiyama, Yoshikazu Hasegawa, Hisashi Oishi, Yoshihiro Miwa, Saori Mizuno-Iijima, Seiya Mizuno, Miki Matsuo, Masatsugu Ema, Noriko Kajiwara, Ken-ichi Yagami, Kazuyuki Mekada
Publikováno v:
Experimental Animals
Cre/loxP system-mediated site-specific recombination is utilized to study gene function in vivo. Successful conditional knockout of genes of interest is dependent on the availability of Cre-driver mice. We produced and characterized pancreatic β cel