Zobrazeno 1 - 10
of 73
pro vyhledávání: '"Gerhard Schenk"'
Autor:
Luel M.O. Costa, Iago S. Reis, Christiane Fernandes, Marcelo M. Marques, Jackson A.L.C. Resende, Elizabeth H. Krenske, Gerhard Schenk, Lawrence R. Gahan, Adolfo Horn
Publikováno v:
Journal of inorganic biochemistry. 239
We report the synthesis of a new asymmetric heptadentate ligand based on the 1,3-diaminopropan-2-ol backbone. The ligand 3-[[3-(bis-pyridin-2-ylmethyl-amino)-2-hydroxy-propyl]-(2-carbamoyl-ethyl)-amino]-propionamide (HL1) contains two amide and two p
Publikováno v:
Journal of Inorganic Biochemistry. 238:112061
Biomimetics hold potential for varied applications in biotechnology and medicine but have also attracted particular interest as benchmarks for the functional study of their more complex biological counterparts, e.g. metalloenzymes. While many of the
Autor:
Filipy Gobbo Maranha, Cláudia Donald Pereira, Nathalia Castilho, Giliandro Farias, Hernán Terenzi, Gerhard Schenk, Rosely A. Peralta, Bernardo de Souza, Ademir Neves
Publikováno v:
JBIC Journal of Biological Inorganic Chemistry. 24:675-691
In this paper, the catalytic effects of aminoguanidine and aminopurine groups in the second sphere of a FeIIIZnII complex that mimics the active site of the metallohydrolase purple acid phosphatase (PAP) are investigated, with a particular view on DN
Autor:
Marc T. Morris, Yonatan Mendels, Rozanne Stroek, Taeuk Kang, Gerhard Schenk, William Goracke, Alice Clark, Andrew Douw, Febe Vermue, Elaine B. Schenk, Stefan Krco, Maria C.R. Gutierrez, Liam A. Wilson, David García, Esmée Gianna Knaven, Marcelo Monteiro Pedroso, Nataša Mitić
Publikováno v:
Journal of Inorganic Biochemistry. 226:111637
Resistance to β-lactam antibiotics, including the “last-resort” carbapenems, has emerged as a major threat to global health. A major resistance mechanism employed by pathogens involves the use of metallo-β-lactamases (MBLs), zinc-dependent enzy
Autor:
Rosely A. Peralta, Hernán Terenzi, Tiago Bortolotto, Ademir Neves, Adailton J. Bortoluzzi, Marcos Paulo da Silva, Cristine Saibert, Gerhard Schenk
Publikováno v:
Journal of inorganic biochemistry. 213
The research reported herein focuses on the synthesis of two new Cu(II) complexes {[Cu2(2-X-4,6-bis(di-2-picolylamino)-1,3,5-triazine], with X = butane-1,4-diamine (2) or N-methylpyrenylbutane-1,4-diamine (3)}, the latter with a pyrene group as a pos
Autor:
Krzysztof Brzezinski, Monalisa Mohanty, Sonaleen Biswal, Ekkehard Sinn, Adolfo Horn, Atanu Banerjee, Saswati, Hans Reuter, Gerhard Schenk, Rupam Dinda
Publikováno v:
Journal of inorganic biochemistry. 203
Two new dimeric Zn(II) ([{ZnL1(DMSO2)}2]·DMSO (1), [{ZnL2Cl}2] (2)) and a novel tetrameric Zn(II) complex ([(Zn2L3)2(μ–OAc)2(μ3–O)2] (3)), where H2L1 = 4–(p–methoxyphenyl) thiosemicarbazone of o–hydroxynapthaldehyde, HL2 = 4–(p–metho
Autor:
Cláudia Chaves, Hernán Terenzi, Douglas R. Norberto, Edgar H. Lizarazo-Jaimes, Dawidson Assis Gomes, Tiago Bortolotto, Gerhard Schenk, David L. Tierney, Ademir Neves, Tiago P. Camargo, Elene Cristina Pereira Maia, Rosely A. Peralta
Publikováno v:
Inorganic Chemistry. 57:187-203
Herein, we report the synthesis and characterization of two dinuclear FeIIIZnII complexes [FeIIIZnIILP1] (1) and [FeIIIZnIILP2] (2), in which LP1 and LP2 are conjugated systems containing one and two pyrene groups, respectively, connected via the dia
Autor:
David L. Ollis, Dean E. Wilcox, Nataša Mitić, Gerhard Schenk, Margaret C. Carpenter, Lawrence R. Gahan, Marcelo Monteiro Pedroso, Fernanda Ely
Publikováno v:
Biochemistry. 56:3328-3336
Glycerophosphodiesterase (GpdQ) from Enterobacter aerogenes is a binuclear metallohydrolase with a high affinity for metal ions at its α site but a lower affinity at its β site in the absence of a substrate. Isothermal titration calorimetry (ITC) h
Autor:
David L. Paterson, Mark A. T. Blaskovich, Alysha G. Elliott, Hanna E. Sidjabat, Soumya Ramu, Gerhard Schenk, Theresa Kolmar, Kevin Synnatschke, Zyta M. Ziora, Mark E. Cooper, Marcel Hergert, Jasper S. Möhler, Liam A. Wilson
Publikováno v:
Journal of Inorganic Biochemistry. 167:134-141
Alternative solutions need to be developed to overcome the growing problem of multi-drug resistant bacteria. This study explored the possibility of creating complexes of antibiotics with metal ions, thereby increasing their activity. Analytical techn
Autor:
Nelson Carvajal, Liam A. Wilson, Elena Uribe, David García, José Manuel Benítez, María De Los Ángeles García-Robles, Vasthi López, Gerhard Schenk, Arlette González, Nicol Romero, Leonardo Bennun
Publikováno v:
Journal of Inorganic Biochemistry. 166:122-125
Agmatine (1-amino-4-guanidinobutane) plays an important role in a range of metabolic functions, in particular in the brain. Agmatinases (AGMs) are enzymes capable of converting agmatine to the polyamine putrescine and urea. AGMs belong to the family