Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Maria Diaz"'
Autor:
Matthew C. Coffey, Richard G. Vile, Timothy Kottke, Hardev Pandha, Alan Melcher, Jill Thompson, Kevin J. Harrington, Shane Zaidi, Kevin G. Shim, Christopher Parrish, Liz Ilett, Rosa Maria Diaz, Karishma Rajani
Publikováno v:
Molecular Therapy. 24:166-174
Oncolytic reovirus can be delivered both systemically and intratumorally, in both preclinical models and in early phase clinical trials. Reovirus has direct oncolytic activity against a variety of tumor types and antitumor activity is directly associ
Autor:
Kevin G. Shim, Timothy Kottke, Nicolas Boisgerault, Kevin J. Harrington, Shane Zaidi, Jill Thompson, Laura Evgin, Peter Selby, Diana Rommelfanger, Hardev Pandha, Richard G. Vile, Rosa Maria Diaz, Elizabeth Ilett, Alan Melcher, Matthew C. Coffey
Understanding how incompletely cleared primary tumors transition from minimal residual disease (MRD) into treatment-resistant, immune-invisible recurrences has major clinical significance. We show here that this transition is mediated through the sub
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de43de651a3b9fba7a3b2ea55d6d0393
https://europepmc.org/articles/PMC5858196/
https://europepmc.org/articles/PMC5858196/
Autor:
Alan Melcher, Feorillo Galivo, Jill Thompson, Kevin J. Harrington, Steven M. Albelda, Rosa Maria Diaz, Timothy Kottke, Phonphimon Wongthida, Candice Willmon, Richard G. Vile
Publikováno v:
Molecular Therapy. 19(1):140-149
Despite having potent oncolytic activity, in vitro, direct intratumoral injection of oncolytic vesicular stomatitis virus (VSV) into established AE17ova mesothelioma tumors in C57Bl/6 mice had no therapeutic effect. During studies to combine systemic
Autor:
Jill Thompson, Rosa Maria Diaz, Phonphimon Wongthida, Timothy Kottke, Alan Melcher, Feorillo Galivo, Richard G. Vile
Publikováno v:
Molecular Therapy. 19:150-158
We show here, for the first time to our knowledge, that the antitumor therapy of oncolytic vesicular stomatitis virus (VSV) in the B16ova model depends upon signaling through myeloid differentiation primary response gene 88 (MyD88) in host cells. VSV
Autor:
Jill Thompson, Timothy Kottke, Jose S. Pulido, Rosa Maria Diaz, Richard G. Vile, Feorillo Galivo, Phonphimon Wongthida, Alan Melcher, Larry R. Pease, Kevin D. Pavelko
Innate immune effector mechanisms triggered by oncolytic viruses may contribute to the clearance of both infected and uninfected tumor cells in immunocompetent murine hosts. Here, we developed an in vitro tumor cell/bone marrow coculture assay and us
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20bbc3b37fe5741984a5c61681073a1a
https://europepmc.org/articles/PMC3896099/
https://europepmc.org/articles/PMC3896099/