Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Manabu, Igarashi"'
Autor:
Haruhiko Kamiki, Shin Murakami, Takashi Nishikaze, Takahiro Hiono, Manabu Igarashi, Yuki Furuse, Hiromichi Matsugo, Hiroho Ishida, Misa Katayama, Wataru Sekine, Yasushi Muraki, Masateru Takahashi, Akiko Takenaka-Uema, Taisuke Horimoto
Publikováno v:
J Virol
Avian or human influenza A viruses bind preferentially to avian- or human-type sialic acid receptors, respectively, indicating that receptor tropism is an important factor for determining the viral host range. However, there are currently no reliable
Publikováno v:
International Journal of Molecular Sciences, Vol 18, Iss 12, p 2649 (2017)
Influenza A virus (IAV) matrix protein 2 (M2) is among the smallest bona fide, hence extensively studied, ion channel proteins. The M2 ion channel activity is not only essential for virus replication, but also involved in modulation of cellular homeo
Externí odkaz:
https://doaj.org/article/1e770c9ba383496cbd3a7db66493504d
Publikováno v:
PeerJ
PeerJ, Vol 9, p e11552 (2021)
PeerJ, Vol 9, p e11552 (2021)
Background Oseltamivir (OTV)-resistant influenza virus exhibits His-to-Tyr mutation at residue 274 (H274Y) in N1 neuraminidase (NA). However, the molecular mechanisms by which the H274Y mutation in NA reduces its binding affinity to OTV have not been
Autor:
Hiroko Miyamoto, Ayato Takada, Reiko Yoshida, Rashid Manzoor, Yoshihiro Takadate, Masahiro Kajihara, Junki Maruyama, Hirohito Ogawa, Wakako Furuyama, Tatsunari Kondoh, Masahiro Sato, Naganori Nao, Manabu Igarashi
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-8 (2019)
Scientific Reports
Scientific Reports
Two novel influenza A virus-like genomes were detected in fruit bats in Central and South America. However, the biological properties of these bat-derived influenza viruses (BatIVs) are still largely unknown since infectious viral particles have neve
Autor:
Manzoor, Rashid1 manzoor@czc.hokudai.ac.jp, Manabu Igarashi1,2 igarashi@czc.hokudai.ac.jp, Ayato Takada1,2,3 atakada@czc.hokudai.ac.jp
Publikováno v:
International Journal of Molecular Sciences. Dec2017, Vol. 18 Issue 12, p2649. 16p.
Autor:
Manabu Igarashi
Publikováno v:
YAKUGAKU ZASSHI. 135:1015-1021
For the prevention and control of infectious viral diseases, vaccines and antiviral drugs targeting viral proteins are of great importance. Amino acid substitutions in viral proteins occasionally cause the emergence of antibody-escape and drug-resist
Autor:
Shinichiro Nakamura, Yasushi Itoh, Misako Nakayama, Kazumasa Ogasawara, Masatoshi Okamatsu, Michiko Doi, Masanori Shiohara, Hiroshi Kida, Yoshihiro Sakoda, Hideaki Ishida, Hirohito Ishigaki, Akihiro Ishii, Naoko Kitagawa, Hideaki Tsuchiya, Manabu Igarashi, Shintaro Shichinohe, Takako Sasamura
Publikováno v:
Antimicrobial Agents and Chemotherapy. 59:4962-4973
The number of patients infected with H7N9 influenza virus has been increasing since 2013. We examined the efficacy of neuraminidase (NA) inhibitors and the efficacy of a vaccine against an H7N9 influenza virus, A/Anhui/1/2013 (H7N9), isolated from a
Autor:
Naganori Nao, Junya Yamagishi, Hiroko Miyamoto, Manabu Igarashi, Rashid Manzoor, Aiko Ohnuma, Yoshimi Tsuda, Wakako Furuyama, Asako Shigeno, Masahiro Kajihara, Noriko Kishida, Reiko Yoshida, Ayato Takada, Mary K. Estes
Publikováno v:
mBio, Vol 8, Iss 1 (2017)
mBio, Vol 8, Iss 1, p e02298-16 (2017)
mBio
mBio, Vol 8, Iss 1, p e02298-16 (2017)
mBio
Highly pathogenic avian influenza viruses with H5 and H7 hemagglutinin (HA) subtypes evolve from low-pathogenic precursors through the acquisition of multiple basic amino acid residues at the HA cleavage site. Although this mechanism has been observe
Autor:
Bernard M. Hang’ombe, Wilbroad Chansa, Jack Chulu, Chuma Simukonda, Boniface Namangala, Yuka Suzuki, Manabu Igarashi, Chihiro Sugimoto, Ayato Takada, Hiroshi Kida, Ichiro Nakamura, Aaron S. Mweene, Akihiro Ishii, Kimihito Ito, Rashid Manzoor, Hirofumi Sawa, Edgar Simulundu, Ladslav Moonga
Publikováno v:
Journal of General Virology. 92:1416-1427
Although the quest to clarify the role of wild birds in the spread of the highly pathogenic H5N1 avian influenza virus (AIV) has yielded considerable data on AIVs in wild birds worldwide, information regarding the ecology and epidemiology of AIVs in